Conserved Protein Domain Family
BTB_POZ_KCTD20

?
cd18386: BTB_POZ_KCTD20 
BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 20 (KCTD20)
KCTD20, also called potassium channel tetramerization domain containing 20, is a positive regulator of Akt signaling. It may play an important role in regulating the death and growth of some non-nervous and nervous cells. It contains a BTB/POZ domain, a common protein-protein interaction motif of about 100 amino acids. KCTD family BTB domains can adopt a wide range of oligomerization geometries, including homodimerization, tetramerization, and pentamerization.
Statistics
?
PSSM-Id: 349694
Aligned: 3 rows
Threshold Bit Score: 227.924
Created: 13-Oct-2017
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q7Z5Y7       115 APEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGReYNFTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGIS 194 human
XP_015154631 108 APEKVTLVVDGTRFAVNPQIFTAHPDTMLGRMFGPGReYNFTRPNEKGEYEIAEGISSAVFRTVLDYYKTGIINCPDGIS 187 chicken
XP_014347480  45 TPERVTLIVDNTRFVVDPNIFTAHPDTMLGRMFGPAReYNFTRPNEKGEYEIAEGISCTVFHAILDYYKTGIIHCRDGVS 124 coelacanth
Q7Z5Y7       195 IPDLRDTCDYLCINFDFNTIRCQD 218 human
XP_015154631 188 IPDLRDTCDYLCINFDFNTIKCQD 211 chicken
XP_014347480 125 IPELREACDYLCINFEYNTIKCRD 148 coelacanth
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap