3J21,3CC2


Conserved Protein Domain Family
rpl4p_arch
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TIGR03672: rpl4p_arch 
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50S ribosomal protein uL4, archaeal form
One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
Links
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Statistics
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PSSM-Id: 274715
Aligned: 30 rows
Threshold Bit Score: 320.716
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3J21_D         1 MKVKVFDLNGQPVGEIELPKVFFTPFRPDLIRRAVIASWTHRIQPQGRDPMAGKRRVT------ENIGK--GHSMARVER 72  Pyrococcus furi...
Q9YFM1        14 KIVPVYDERGGEKDSVVLPQIFRFPVRKDLIRRAFLSEFTARLQPKGRDPMAGKRTSA------VSLGV--GRGVARVPR 85  Aeropyrum perni...
P60847         1 MEVPLYNLQASQVGNIELPPQFNEKIRFDVIKRAFLAIQSHKRQPYGASPIAGKQHSAwtskrrRSWRTsyGRGISRVSR 80  Nanoarchaeum eq...
Q8ZW51        27 EKLKVYGIDGAYVADIEAPLHFLEPIRPDLIRRAYLSALSARFQPKGVYEGAGKEHSC------ESFGV--GLGIARIPR 98  Pyrobaculum aer...
Q4JB41         8 KKVSVLDLKGNQLEEIELPLFFSYPVRKDLIRRVFLSEFTKSLQPKGRDPLAGKRTSA------LSFGI--NLGIARVPR 79  Sulfolobus acid...
Q9UXA6         8 KKSDILDKDGNRIKEVELPIIFSFPVRKDLIRRVFIAEFTHSLQPKGRDPNAGKRTSA------ESFGI--NLGMARVPR 79  Sulfolobus solf...
Q9HIR0         3 TKVPIYSVSGEMKGEIDLPEVFDTEVREDIIRRAFRAISLSMRQPYGSSPLAGMRRVG------HTTRP--GLGISRMPR 74  Thermoplasma ac...
WP_010978401  11 KKTHIFDLKGNKVEEIELPIFFSYPVRKDLIRRVFISEFTKALQPKGRDPMAGKRTSA------LSFGI--NLGLARVPR 82  Sulfolobus toko...
WP_011822451  17 pRVPVYNLEGSVAEEVQLPRVFGLPVRIDLIRRAFLSEFTARLQPKGRDPLAGKRTTA------RSFGV--GLGIARVPR 88  Hyperthermus bu...
WP_011839306  14 qETYVFSSDGEKVEEITLPPIFSLPVRKDLIRRAFLSAFTSMLQPKGRDPLAGKRTTA------RSWGV--GRGLARVPR 85  Staphylothermus...

3J21_D        73 --LKTPP-----RyAAFVPFARGGRRTHPPKVEKIIWEDINKKEKRLALMSAIAATANYDLVRARGHIIDNVpQLPLIVV 145 Pyrococcus furi...
Q9YFM1        86 --IKGSL-----R-AALVNMARGGRAAHPPRVEKVLKEYINKKEKRLATISAISATSREDLVRQRGHRFSAE-TLPIVLD 156 Aeropyrum perni...
P60847        81 aiLRRHGalfywV-ARNIAQAVKGKKAHPPKAEKDWYEKINKKERRLAIRSALAATKELDLVKARGHIIDK--PVPIVV- 156 Nanoarchaeum eq...
Q8ZW51        99 --YKGSLw---pR-GCFAPNTRGGRRAHPPKVEKKLHEEINKKEKKLAIRSAIAATAYRSWVAARGHVVEKVpSLPVVVV 172 Pyrobaculum aer...
Q4JB41        80 --VKGSG-----E-AALAPNTVGGRLAFPPTTEKRLVEEVNLKEKKLGIISALAATADPNFVKARGHRFTSN-NVPIILV 150 Sulfolobus acid...
Q9UXA6        80 --VKNSG-----E-AALAPNTVGGRLAFPPSVNKKLAEEANVKEKRLAVISALSATADIAFVRARGHVFKDSvRFPIVVT 151 Sulfolobus solf...
Q9HIR0        75 --IAGGS-----R-VVGIASAVGGKSAHSPRTTKNLYVKINDRERKMAKYSAIALTASVEAVKKRGHRFKEGlKLPIVVE 146 Thermoplasma ac...
WP_010978401  83 --VKTTG-----E-AALAPNTVGGRLAFPPTVEKKLVEEVNKKEKKLAIISALSATANMNFVKNRGHVFSID-TLPIIVV 153 Sulfolobus toko...
WP_011822451  89 --IPGLG-----R-AAFINSAVGGHLAHPPRVEKKIHEEINKKEKKLATASALAATARKEFVEKRGHRFPAQ-TVPVIVV 159 Hyperthermus bu...
WP_011839306  86 --LPN-S-----R-AAFISFARGGHAAFPPRPDERIHERINKREKAYAVASAIAATAKVDLVRGRGHVFQQD-KLPVVLL 155 Staphylothermus...

3J21_D       146 DDLQ-KVQKTRETREIFKKLGIWDDIVRAKEKSGVRAGKGKMRGRRYKKAKGPLIVVGK-NEG-IVLGARNHPGVDVVVV 222 Pyrococcus furi...
Q9YFM1       157 SSVLaKISTAREARSLLESVGVYEDVLRAKEGKRYNAGKGKMRGRRYKVPKSVLFVLEDpRSP-LALAVKGMPGVDVVTP 235 Aeropyrum perni...
P60847       157 DGLE-QLRKTKEIQQLLLKLGLEKELERVYEIKR-RAGKGKRRGRAYIERKGPLIVVNDyNEQ-LFKAVDNIPGLDIEEV 233 Nanoarchaeum eq...
Q8ZW51       173 GDAE-KINRAKEAKKLFEALGLWPDVERAAEGVKIRAGKGKMRGRRYKEPKSVLVVVSDlNAP-LIAAVRNFPGVDVVAV 250 Pyrobaculum aer...
Q4JB41       151 DDFE-NISKAKEIMDILKSIGVVDDIKRVKESKGVRAGKGKMRGRRYQIAKGPLIVVSNhKSP-VVESASNIPGVNVVSA 228 Sulfolobus acid...
Q9UXA6       152 DDIV-NLKTTSEVEEFLKKIGVYDDVERVKERIRIRAGKGKMRGRKYKEPIGPLIIVHDsNSP-IIKAARNLAGVDVVNA 229 Sulfolobus solf...
Q9HIR0       147 DGVE-GINKTKDAIALLKNLGVYEDIERSREGKHIRAGRGKMRGRRYKQPKSVLIVARN--SS-AMKAFRSLPGVDIASP 222 Thermoplasma ac...
WP_010978401 154 DDIT-KLTKTKEIIEVLESLKVYEDVERVKDRIRIRSGKGKMRGRRYKEPKGPLFVIHE-NNPvFVKAASNIPGVDVILA 231 Sulfolobus toko...
WP_011822451 160 DEVEtSITRVKEAKLLLEKLGVWSDIERAKERTRIRAGKGKRRGRRYITPKSILFIVSNhNSS-FARAVAGLPGVDVAEP 238 Hyperthermus bu...
WP_011839306 156 DDVEdKISKARDAKELLIKLGLWSDIVRSYERIRIRAGKGKMRGRRYVEPRSILFVVTSyDKP-FAKAVRNFPGVDVATP 234 Staphylothermus...

3J21_D       223 DNLGVEHLAPGTHPGRLTVWTVSAIERLREL 253 Pyrococcus furiosus DSM 3638
Q9YFM1       236 TLLSVLHLAPGGHPGRLTIYTTEALKLLSRR 266 Aeropyrum pernix K1
P60847       234 PNLNVELLAPGAKPGRLLIISKDALETLRER 264 Nanoarchaeum equitans Kin4-M
Q8ZW51       251 NNLNILVLAPGGVPGRLTLWTAPAVEKLRGL 281 Pyrobaculum aerophilum str. IM2
Q4JB41       229 NLVSVIHLAPGGHPGRLTIYTKSSINILRQR 259 Sulfolobus acidocaldarius DSM 639
Q9UXA6       230 KDVSVIHLAPGAHPGRLTIYTESSIKILDER 260 Sulfolobus solfataricus P2
Q9HIR0       223 NSLSIRKLAPGGVGGRLTIFTEGAIESLKEV 253 Thermoplasma acidophilum DSM 1728
WP_010978401 232 SDLSVIHLAPGGHPGRLTIYTKSSIDVLRKR 262 Sulfolobus tokodaii
WP_011822451 239 WNVNVLQLAPGGVPGRLTVITRSALEELGKR 269 Hyperthermus butylicus
WP_011839306 235 NNLGILHLAPGGVPGRLTVFTRSAIEDISRK 265 Staphylothermus marinus
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