Conserved Protein Domain Family
YxeI

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COG3049: YxeI 
Penicillin V acylase or related amidase, Ntn superfamily [Cell wall/membrane/envelope biogenesis, General function prediction only]
Statistics
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PSSM-Id: 442283
Aligned: 209 rows
Threshold Bit Score: 166.98
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AFZ26817      54 LLGCTRAIYVA-----NEEt--kSIFTMRSMDWA-Dp-N-MSISLWASPRNSYRT-G-V----GEsdeGYPL-TWESKYK 116
YP_170192     22 SLACTALTLV------KNG----QTVSGRTMEWG-F--N-WSWQLIYIPKGTKHY-L-SapsnLN---LAKI-SYASKYS 81 
WP_043878734  18 ALACTAVDIVA-----ADR----TVIAGRTMEWA-F--D-MKWTLVSRPKGFPVK-L-TapkaLN---LPER-TVEAKYA 78 
WP_011903413  29 SNACTSFLLKG-----SDG----GSVYGRTMEFG-I--P-LQSQLMTIPRAYELK-G-Vg--iDGn-yGTGQ-SWITKYA 89 
WP_012114384  21 AVACTAVNVVA-----ADK----TVIAGRTMEWA-F--D-MKWTLKSIPKGTSLT-L-TaptdLG---LPEK-TVATLYS 81 
WP_084593835  37 SIACTAVTLVD-----IKQ----NVVSGRTMEWG-F--D-WDWKVIYIPKNTEQS-L-TapanLR---LPAQ-TYKSKYS 97 
WP_060690446   1 --MCTGIRLIA-----NDG----SPVFGRTEEFA-Ee-M-LHMHLLKAGRGTKFR-G-At--hEG---ENGM-SWEADYG 58 
WP_055731605  22 AHACSRLVTDT-----QHG-----TLVIRTADWY-SaaP-FDGHVSVFPVASQRTmRgEvs-----syKNAYqQWQTKYH 84 
WP_096378912  40 SAMCTNFLLTVpnvpaAAGqpalQHISARCMELT-G--T-LATRLYRVPALQQFPv-------FK---SHSQ-PWVGSYG 104
WP_100920375  24 ANACSDIILDPak--tLNK----QVVSARTMDFPgM--DyWQSQLSRVTRGVTWR-Sfd---fSG---VPGR-QWTNQYG 87 
AFZ26817     117 SLV-VCN---YG--------KSTTDGINEEGLVANLLFLAQ---A-DYTHD--Eq--SNKPRLPISGLAQYVLDNYANVQ 176
YP_170192     82 IIA-TGLv--NAn------qEFLVDGQNDQGLSISANYMPGf--A-EYQKV--Tn--TDKKYASINQISILILSEYANVE 145
WP_043878734  79 LVG-VSAn--IIp------gGALVEGQNAAGLGMSGNFLPGf--T-TYQTV--Tp--QDKNYVEVLSFGAWALGNFATIA 142
WP_011903413  90 VAG-MNG---Lg-------lPEFFDGINEKGLTGGILNFPIs--A-SFPVV--Tq-aESSSSINASQVLTYVLSNFSTVE 152
WP_012114384  82 VVG-ISAe--VIp------gGAIVEGQNAAGLGMSGNFLPGf--T-TYQTV--Tk--ADTSYVSILGFGAWALGMNGSVA 145
WP_084593835  98 ILG-TGIk--NDh------qTILIDGQNDQGLSISANYLPSf--T-QYQEV--Sk--DNDKYMSILEFTTFILSEFTNVK 161
WP_060690446  59 FVAgIP----Fk-------mQAPIEGLNEAGLQGGVFFFQPydkG-RYQNH--Np-eEFDRTISAWQLLTFLLSKAASVA 123
WP_055731605  85 TVS-FEE---HGaf-----nGLSGHTVNDQGLNVAALSQSD---SePFLAQ--Hk-dNGAPAVNIADVATFIAENYATVA 149
WP_096378912 105 FVG-LCDpetIPe------fTMFMDGINQAGLSCAALWLPG---S-EFAEK--Pg--AGEQPVAFHDFVAWVMSQFDSVP 169
WP_100920375  88 FIG-MDFr--VQegtfaihqRVYNDGMNEEGLSAALLWLEV---G-QFVDRtgDnraAQADDLHYLDLVAWVLGQFAKVE 160
AFZ26817     177 EAVDGLKEEPFFi-vTS-DIA-LatldrenskfkvSTk----NIVLHLSISDSQGNSAVLQYVtDeqtkkSK--LVVY-- 245
YP_170192    146 QVKQALQQYKVW---SD-KST-M------------INg---vAPQLHFLITDRNGKGLVVEYI-K-----GE--VKLY-- 195
WP_043878734 143 EVKEALKTTKVW---SD-PSA-A------------SGp---tAPLMHFVFTDRAGASIIVEYV-E-----GE--LHIH-- 192
WP_011903413 153 EIKVGLRSIKVN---GA-RLA-V------------YNn---qVPAAHYTFHDSNGKSIVVEYL-N-----GQ--LVIT-- 202
WP_012114384 146 EVRAALAKIKVW---AD-ASL-P------------SGp---tPPTLHMVFTDRSGASIVVEYV-G-----GE--LQIH-- 195
WP_084593835 162 QAKQVLKEYKVW---SD-STT-M------------VDg---iSPELHFLITDKQGNGLVVEYI-D-----GE--VKLY-- 211
WP_060690446 124 DVKRLVNEIRVV---NSiPQPrT------------PGwe--fEPIAHWAINDDTGAAVVIEYL-D-----GE--LNIF-- 176
WP_055731605 150 EVKAALDNKAFQfawAD-----Ap-----------NGle--hAAGLHYSIVDKDGNIMLIQLG-E-----GG--VPQYel 203
WP_096378912 170 SLVAAMTKVRIV---GP-QPG-Ap-----------------tYLPVHFIATDSQGLSAVIECI-D-----GQ--TIVYgp 219
WP_100920375 161 DVADALDANKAWi-vGT-NVT--------------SGwvplfKLPMHLVVHDRFGHSLIAEWYpTag--sGKptMHLHig 222
AFZ26817     246 ---HfqqdkkdkgkDTVSVMTNS-LYEEQLELLKRFQNEDgefdwagknks-----------fswdklmsnsGFELTPPM 310
YP_170192    196 ---Dv--------nSNVKVMTNApTYDWHLINLRNYLNLSnqtttrvkisdaidps-qnkdiqdinslgqgnGFLGLPGD 263
WP_043878734 193 ---D----------NVAHVLTNApTYDWHLTNLRNYLNLStvgveqrqign-----------vdvtalgqggGLVGLPGD 248
WP_011903413 203 ---D----------NPVTVMTNDpPIGDQLKNIGNYSNLSkvekpplving-----------atfaapssgsGLHGLPGD 258
WP_012114384 196 ---D----------NVASVLTNSpPYDWHLLNLRNYLNLStmgvgdrrfgt-----------anvtaigqggGATGLPGD 251
WP_084593835 212 ---Dl--------nSNVKVMTNApTYDWHLINLRNYLNLSnktivkvkisdfidnkdkqktiqdinglgegnGFLGLPGD 280
WP_060690446 177 ---D----------NPLGTITNApAFPWHQENLKQFTSLPidqrppferqtg----------eqgasgldigsKTNLPGQ 233
WP_055731605 204 --gDa--------dSDLRVKTNDpFQNKQREFVSQFdik------------------------------dpkVAASLPWG 243
WP_096378912 220 dyrDg--------aTNDAVLTNApTYDWHRTNIENYAHLSvvgtgtsrk---------------aggvpvgaGLVGLPGD 276
WP_100920375 223 --sQv---------DSVGVLANDpVYPDQLTNLALYSGIRnkdsae---------------------gagdgAMAGTPGG 270
AFZ26817     311 NGANIRFLRASFYSNRMD-K-IDNnyqnqrpfidetnrvlgnpesysiwvdkwsQNEG-VARAFSLIRNL-STPLNIqGI 386
YP_170192    264 YSPPSRFIKTAILGYYAN-N-KGD------------------------------NNENlVTKVTHILNNV-DITKGT-VT 309
WP_043878734 249 YTPPSRFVRASALRHGMT-P-PKD------------------------------GAEA-VQAVVHVLNTV-DIPVGV-AQ 293
WP_011903413 259 FLSPSRFIRALFLSDSVP-K-TFT------------------------------TAQM-GDAAWHILGSF-DIPPGS-VT 303
WP_012114384 252 FTPPSRFVRAAFMRHSMA-Q-PKD------------------------------AATA-TAAIGHVLNTV-DIPLGV-AQ 296
WP_084593835 281 YSPSSRFIKIAMLAYYAN-N-ENP------------------------------SQESlVTKVAHILHNV-DIVKGT-IV 326
WP_060690446 234 ITSANRFVRASIFTQYAF-P-FAD------------------------------STEG-VKRVLNILNNF-DIPLGY-KT 278
WP_055731605 244 IGGKQRNVRLLAVSEQLNtE-GLN------------------------------YQQT-VARQRSAMDVAgTVPFEI-QD 290
WP_096378912 277 ITSISRYVKAWTLRQGFA-KlPKDgngwlpta---------------kldgatgSTQTiVNVALQLVTTIqATPYGT-AL 339
WP_100920375 271 FDSPSRFVRLAKIRQFLG-E-VVDggev----------------------dlynQVGA-VPQALHAINNV-DLGHGV-DN 323
AFZ26817     387 NNN-PFL--------SSTLWRTVIDHKKNRYFFESTRGL-CPLYVDLDEF--FKD-L----ET----VKK----LDILLS 441
YP_170192    310 EKL-Gnqt-----mfDHTAFTVIKDLNNNKLYIKSYNSPnNAVEIDLNTLd-QNN-S----KQfaidIDK----LPYPNN 373
WP_043878734 294 SRL-PNGql----vsDYTQWVSIKDLTNNRLQIADYAHRtSYLTIDLAPLfaLDKpA----ER----LITd---LPYPAG 357
WP_011903413 304 LPA-SNPyggglggyEVTEWSVVANNKDMTYNVKMYENN-NIYTFDLKKMd-MN--A----KE----IRY----TKL-NQ 365
WP_012114384 297 SKD-Gdtv-----vsDYTQWVAIKDLTHNRMMISDYAHRaTFLTLDLDAIfaQDKpS----AR----LVTd---LPFPAA 359
WP_084593835 327 EKI-Gdkt-----lyDHTAYTVIKDLDKNLLYLSSYSNPtNSVVISLNKLd-QNN-A----KAfdtiIKN----IKTPST 390
WP_060690446 279 YKN-VDGdi----fpQYTSFTTISDLRNRVLYFRLFGNP-TLHKVDLKEVd-FS--K----SE----ITF----VPV-NN 336
WP_055731605 291 PAT-GED--------YPTFFTVQLNLDNGDIWFRSEMTR-ADMSFNIEDTkgFSQ------------AMT----ANIQQQ 344
WP_096378912 340 VDK--DAraq---lgDWTMWQVARDHTNIAYYFNTAFNA-SVHGVQLSGLd-FTG-G----SA----AAKdwpsVPVMPA 403
WP_100920375 324 DPLmPGVpmf--gvyQETGVTLVRDHTNRVIYFKGLHYQ-TLQRIEFAKVd-FTGiAggvvGPs---IPAd--vLPAKSS 394
AFZ26817     442 PtkkgdqgidlledqlnkgIKIGKVNHEF 470
YP_170192    374 N------------------ISANLIT--- 381
WP_043878734 358 Vgadvlkp--------------------- 365
WP_011903413 366 P------------------KIMIPVN--- 373
WP_012114384 360 Vdgtaalrn-------------------- 368
WP_084593835 391 D------------------ITNNFL---- 397
WP_060690446 337 E------------------FTTVPVNMNV 347
WP_055731605 345 Vdngateltwkayq--------------- 358
WP_096378912 404 Qg-----------------PWFQDVSANL 415
WP_100920375 395 Rytqgvdvsakltaprviyphrplpwpan 423
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