Conserved Protein Domain Family
GIY-YIG_unchar_3
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cd10448: GIY-YIG_unchar_3 
GIY-YIG domain of uncharacterized hypothetical protein found in bacteria
The family includes a group of uncharacterized bacterial proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.
Links
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Statistics
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PSSM-Id: 198395
Aligned: 79 rows
Threshold Bit Score: 104.885
Created: 7-Oct-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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putative activeputative metalGIY-YIG
Feature 1:putative active site [active site]
Evidence:
  • Comment:Based on similarity to the sequence of Enterobacteria phage T4 homing endonuclease I-Tevi (1LN0).
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1           #           # #             #   #                                 #          
NP_966153      4 SYIYILTNk-aNSTLYIGVTA------NLIKRIWEHKNKiv-sgFTSRYNVNKLVYFEEFEDIsLAIARERRLKEWPRQW 75  Wolbachia endos...
ZP_01916450   30 YWLYILSNskpNGPLYLGDTN------CLLTRMDEHIQGlr-rdYAHYHRLDRLVYFEVWTDHdKFVARLRRVRNWPRDM 102 Limnobacter sp....
ZP_08183153   21 SVVYLLAHa-rREAFYIDVASglgaisDTRRRIIVQQEAs---lPRERVMPLLLVWFEACTDLaAAKARATQLRAWPHAW 96  Xanthomonas gar...
YP_003092183   3 KFVYVVTDr-nRTSLHVGMSS------DLIKTLDFYKQMpc-llFDSGQQLTRLVYFEELKTEaQALSRFKLISRFTRTQ 74  Pedobacter hepa...
YP_004273595   3 NIVFIVTDa-nRKTLHVGMSS------DLIKTMDFYAKIpn-llFHTDQKLTSLVYFEEFNSEiTANKRFSALSKYTRAQ 74  Pedobacter salt...
ACX76174       5 YYTYMMTNq-sNTTLYVGVTN------DISRRALEHIEGcg-atFTSRYKINKLIYFERYTEItDAIKREKQLKGWRREK 76  Fibrobacter suc...
ZP_03129703   19 LFVYILTSe-rRTTLYIGVTN------NLEGRLWQHQNGeg-skFAHHYNLTVLVYYETWPDPaSAIARETQLKGWTRAK 90  Chthoniobacter ...
YP_004273654   6 GFVYILTNk-nKTVLYIGVTS------DLKGRIWEHMNSnnrqsFTFRYNVLYLVYYEFLDSIsQAIDREKQLKRWSREK 78  Pedobacter salt...
ZP_01062387    5 FYIYILTNk-nHTVLYIGVTS------DLKRRLKQHKQKsn-kgFTRKYNVEKLLYFESSPYVeNAIKREKQLKKWNRAW 76  Leeuwenhoekiell...
AEB27359       4 GYVYILTNk-nNSVLYVGVTS------DIVKRIYEHKNKfv-dgFSRRYNLEKLVYFELYQNIeDAIIREKQLKKWNRAW 75  Francisella tul...

Feature 1                #      
NP_966153     76 KinLINQKNPSWIDL 90  Wolbachia endosymbiont of Drosophila melanogaster
ZP_01916450  103 RllLIESLNPDWDNL 117 Limnobacter sp. MED105
ZP_08183153   97 RrqLVETLNPAWIDL 111 Xanthomonas gardneri ATCC 19865
YP_003092183  75 KerLVRSCNPDWIDL 89  Pedobacter heparinus DSM 2366
YP_004273595  75 KekLIRDVNNNWLDL 89  Pedobacter saltans DSM 12145
ACX76174      77 KeiLIMQMNPLWKDL 91  Fibrobacter succinogenes subsp. succinogenes S85
ZP_03129703   91 KdaLISTLNPTWEDL 105 Chthoniobacter flavus Ellin428
YP_004273654  79 KedLINKMNPTWGFL 93  Pedobacter saltans DSM 12145
ZP_01062387   77 KenLINEMNPDWNDL 91  Leeuwenhoekiella blandensis MED217
AEB27359      76 KnrIINGMNPKWDDL 90  Francisella tularensis subsp. novicida GA99-3549

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