Conserved Protein Domain Family
Lon

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COG0466: Lon 
ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 440234
Aligned: 746 rows
Threshold Bit Score: 929.041
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_025413420   1 M------------AQRRTLPVLPLRGTVIFPGVTQPIAAGRP----GTLRAIEAALK---------------------G- 42 
WP_015894159   1 MprgqrkeeilraELPPTLPLMALRSTIVYPLGTIAVQMGAP----ENLALLRAHEE---------------------S- 54 
WP_015941610   1 Msdetlh-dqpneETPETLPLIPLEGVVVFPHTVVSLTLDD-----LGVPAAEAAVR---------------------E- 52 
WP_015804567   1 M------------GDTLALPVLPLDDTVVLPGMVVPVRLTGSdagaEARAAVEAATSaa-----------------ggVn 51 
WP_015794247   1 Msen-------mtGATKAFPVIPLDDAVVLPGMVVPLDLSDS----ETRAAVDAAANgp-----------------trGg 52 
WP_012918125   1 M------------TETLNLPVLPLDDVVVLPGMVVPVRLADT----EARAAIDAAQA---------------------Sg 43 
WP_012889934   1 M------------SESLILPVLPLDDEVVLPGMVVPLDLSEN----EIRAAIDAAQAl-------------------aDn 45 
NP_629430      1 Maaes------aafTPLTLPVLPLDDEVVLPGMVVPLDLSDA----EVRAAVEAAQAaar----------------sePg 54 
WP_091802026   1 M------------SQPQVLPVLPVDDDVVLPGMIVPLDLGDT----ESRAVIEAAQArvpngislpgirsaqpsaaanTs 64 
WP_054055109   1 M------------SEALTLPVLPLDDTVLLPGMVVPIHLTGSdnaaEARAAIEAAQAg--------------------Te 48 
WP_025413420  43 DRVVFAVAQR-D-NTDEPT--PDILYSMGVIARIGQIQRGL--GgVQLLLQGEQRATALQYNTGDG------YLQAVIMP 110
WP_015894159  55 GLVVALVVASgD--NDDAIepERFVGRVGVAARVHERINLPg-DtVQITLQGLRRITIDAIDQVTP------FSIARIQG 125
WP_015941610  53 GRYVLLAARRpDpPADAPI--VEQFFRVGVVARIEQLGTLPn-GsTGVVVRGLVRAELGEATQTAP------FLRFTFTR 123
WP_015804567  52 GARVLLVPRL-D----------GRYAKVGALATVEQVGRLAg-GeRAAVLRATERVRIGTGTTG-Pg----aALWVEATV 114
WP_015794247  53 KPQVLLVPRL-D----------GTYAKSGVVAIIEQTGRMAgsGrMVAVVRGTNRAAIGVGTTG-Pg----aALWVEAIV 116
WP_012918125  44 QDQVLLVPRL-D----------GKYAKAGTLGEIEQIGRLPg-GaQAAVIRGTARVLIGAGTTG-Pg----aALWVGATV 106
WP_012889934  46 KPEVLLVPRI-D----------GRYGSVGVRAIVEQVGRLPg-GePAAVVRGVDRVRVGSGTTG-Pg----aALWVQATL 108
NP_629430     55 KPRVLLVPRI-D----------GTHAATGVLGTVEQVGRLAd-GdPGALIRGRGRVRIGAGTTG-Pg----aALWVEGTR 117
WP_091802026  65 KAEVLLVPRV-E----------DDLAELGTVATVERIGRMPg-GgSAAVLRGSRRVFLGERADS-PakdadqVQWVHAEP 131
WP_054055109  49 PARVVLVPRL-D----------GKYASVGTLAVVEQVGRLPg-GdLAAVVRGTGRVRIGAGTTG-Pg----aALWVHVET 111
WP_025413420 111 AEEMLplnERDPAFEALHKETRERAAELGERr-GLPEEVVhQVLD-SVSEAGKFSDLVAGYIDLSVPEKQGLLETLSVEE 188
WP_015894159 126 AKETP---PEPAELDELVARTVAAAETLAELvdRIPNEVP-QILKmNVSDPGRFADLAATNMNLRIADKEEVLQRLDIGQ 201
WP_015941610 124 RPDVF---ERTPELEQLMVEAHAAIDAVLELrpGVTQEIR-NFVR-SIDDPGHLADNTGYSPDYTFAERQDLLETFDVVE 198
WP_015804567 115 VEEP----PPDERARSLARDYRAVVTTILq--qRGAWQVV-DSVR-QVDGPSALADLAGYAPYLENDQKVWLLETGDVGD 186
WP_015794247 117 LEEP----AVTSRTRELAKEYKDLAIEILq--hREAFQVV-DMVQ-QISDPSQLADSAGYAPYLKAVQKVELLETLSVDE 188
WP_012918125 107 LNEI-----TDAQSAELAREYKTLITSVLe--rRGAWQVI-DSVR-QVNAPAELSDLAGYASYLSDAQKLELLENANVTE 177
WP_012889934 109 VEAV----QVGERAEELAKQYKALSTTILq--kRGAWQVV-DAVN-QMDDPSVLADSSGYAPWLSTQRKAEILETADPAD 180
NP_629430    118 VDETvp-dPLPGQVAELVKEYKALATAWLr--kRGAWQVV-DRVQ-AIDDVSALADNSGYSPFLTTEQKVELLETTDPVA 192
WP_091802026 132 AIEP----PSGERERELAAEFKAVVVSLLq--qRGGWQML-DAVQ-QLDDPSAIADLAGNAPYLSVEQKLELLRTLDVGA 203
WP_054055109 112 ADET-----VTDEARELAREYKGLVTTILq--qRGAWQVV-DTVN-QIDDPSILADMAGYAPYLTDERKVWLLETTDVAA 182
WP_025413420 189 RLRRVLVHVQRQIGLLEAQEDIKSAVQEELGERQREMFLREQMKAIQKELGE-D--DQN-KEIEELREKLSKLELPREAR 264
WP_015894159 202 RIRFILSRLEREVARARVMEDVKKQTEIKIEQHQREFYLRQQLRAIQSELGEaD--PNE-KESIDLLRRIDEAKLPEKVG 278
WP_015941610 199 RLRKVCDFYRKQFALLEVQARLRQEVQESAAKQQREFYLRQQLKAIQKELGEdG--GEA-AELDDLRQKLAAANLPDVAR 275
WP_015804567 187 RLERLLEWGRAHLAELDVAESIAKDVKEGVEKQQREFLLRQQLAAIRKELAElDg-KPA-TEEQDYRARVEAAELPEKVR 264
WP_015794247 189 RLEKLLTWGREHLVELDVSESIRKDVEDGMEKQQREFLLRRQLAAIRKELAElDg-KEA-SEEEDYRSRVETADLPDKVR 266
WP_012918125 178 RLTKLIGWVKDHLAELEVSESIQKDVQEGMEKQQREFLLRQQLAAVRKELAElDg-STA-SEEEDYRARVEAADLPEHVR 255
WP_012889934 181 RLSLLVEWAREHLAELDVAETIRKDVQEGMEKQQREFLLRQQLAAVRKELSElNgtSPE-TEEEDYRARVEAADLPEKVR 259
NP_629430    193 RLKIATQQLRDHLAEQDVAETIAKDVQEGVDKQQREFLLRRQLEAVRKELREiNg-EQEgEESDDYRARVEAADLPEKVR 271
WP_091802026 204 RLEQALETGRAYLAELRVTDTIRKDVEQDMEKQQKEFLLRRQLDAIRKELGElDg---S-EDKDDYRARVEAADLPEHVR 279
WP_054055109 183 RLAKLLAWGKEHLAELDVAETIRKDVKEGMEKQQREFLLRQQLSAIRKELAElDg-KPA-SEEQDYRARVEQADLPEKVR 260
WP_025413420 265 QEVERELGRLERAGRESMEAQVIRTYLEWIAELPWNTRSD-D-KLDINGASTILDEDHYGLQDVKDRVLEFLAVRQLR-A 341
WP_015894159 279 AEARRETERLRMLSPASSEYQVLRTYLDWVLALPWHTRSAnDqQILLSKVEDALGERHYGLDEAKERIIEYLAVRKLRgG 358
WP_015941610 276 KEADRELNRLARINASSPEYQMVRTYLEWLAELPWNKYTG-Q-PIDIAYTRQVLDEDHHGLQKVKERILEYLAVKQRR-A 352
WP_015804567 265 EAALREVDKLERTSEQSPEVGWIRTWLDTVLDLPWGERTE-D-SYDIAGARAVLDADHAGLDDVKERITEYLAVRRRR-A 341
WP_015794247 267 EAALKEVDKLERSGDQNPEAGWIRTWLDTVLEMPWSERSE-D-SYDIAGARAVLDADHAGLDDVKERIVEYLAVRKKR-Q 343
WP_012918125 256 KAALTEVDKLERTAEQSPEVGWIRTWLDTVLEMPWNERTE-D-SYDIREARAVLDADHAGLDDVKERITEYLAVRRRR-A 332
WP_012889934 260 EAALKEVDKLERTSDQSPETGWIRTWLDTVLDIPWNERTE-D-SYDIAAARAVLDADHTGLDDVKDRIIEYLAVRGRR-A 336
NP_629430    272 EAALKEVDKLERSSDQSPEGSWIRTWLDTVLEMPWSERTE-D-AYDIQGAQAVLDAEHAGLEDVKERITEYLAVRKRR-G 348
WP_091802026 280 KAALAEVDKLERTSEQSPEGGWIRTWLDTVLDIPWTKRTT-D-VHDIAGARAVLDADHAGLDDVKERIIEYLAVRQRR-A 356
WP_054055109 261 AAALSEVDKLERTSEQSPEVGWIRTWLDTVLELPWNSRTE-D-AYDIPGARAILDADHAGLDDVKDRIIEYLAVRKRR-D 337
WP_025413420 342 --------QqiaeevektgevaaaklmpdgddatptlasstndgerqitdkkeakaramARGPILLFTGPPGVGKTSIAK 413
WP_015894159 359 --------D--------------------------------------------------PTGPILCFVGPPGTGKTSLGE 380
WP_015941610 353 llgeenlrA--------------------------------------------------NREPILAFVGPPGVGKTSLGQ 382
WP_015804567 342 --------Drgmgl-----------------------------------------vggrGGGAVLALVGPPGVGKTSLGE 372
WP_015794247 344 --------Dkglel-----------------------------------------vggrRSGAVLALVGPPGVGKTSLGE 374
WP_012918125 333 --------Drglgv-----------------------------------------vggrRSGAVLALVGPPGVGKTSLGE 363
WP_012889934 337 --------Ekglgv-----------------------------------------vggrRSGAVLALAGPPGVGKTSLGE 367
NP_629430    349 --------Drglgv-----------------------------------------vggrRGGAVLALVGPPGVGKTSLGE 379
WP_091802026 357 --------Astvdtvge----------------------------------aevdragrRAGAVLALAGPPGVGKTSLGE 394
WP_054055109 338 --------Erglgi-----------------------------------------vggrRSGAVLALAGPPGVGKTSLGE 368
WP_025413420 414 SIAKALGREYVRVALGGARDEADIRGHRRTYVGAMPGRIIQGMKQAGTKNPVFLLDEVDKLGH-GFQGDPAAALLEVLDP 492
WP_015894159 381 AIAKSIDRAFYRISVGGVRDEAEIRGHRRTYVGAMPGMLIQALRRVEVRDPVIMIDEIDKMSSgGSGGDPTAAMLEVLDP 460
WP_015941610 383 SIARALGRSFVRMSLGGVRDEAELRGFRRTYIGSQPGRIIQELRRAGTADPVILLDEIDKLGI-DYRGDPAAALLEVLDP 461
WP_015804567 373 SVARAMGRKFVRVALGGVRDEAEIRGHRRTYVGALPGRIARAISEAGSMNPVVLLDEIDKVGA-DHRGDPTAALLEVLDP 451
WP_015794247 375 SVARAMGRKFVRVALGGVRDEAEIRGHRRTYVGALPGRIVRAIKDAGTMNPVVLLDEIDKVGA-DYRGDPTAALLEVLDP 453
WP_012918125 364 SVARAMGRKFVRVALGGVRDEAEIRGHRRTYVGALPGRIVRAITEAGSMNPVVLLDEIDKVGA-DYRGDPTAALLEVLDP 442
WP_012889934 368 SVARAMGRKFVRVALGGVRDEAEIRGHRRTYVGAQSGRIVRAVREAGSMNPVVLLDEVDKVGS-DYRGDPTAALLEVLDP 446
NP_629430    380 SVAHAMGRKFVRVALGGVRDEAEIRGHRRTYVGALPGRIVRAIKEAGSMNPVVLLDEIDKVGS-DFRGDPAAALLEVLDP 458
WP_091802026 395 SVAKAMGREFVRVALGGIRDEAEIRGHRRTYVGALPGRIVRAIKEAGSMNPVVLLDEVDKVGA-DYRGDPTAALLEVLDP 473
WP_054055109 369 SVARAMGREFVRVALGGVRDEAEIRGHRRTYVGALPGRIVRAITEAGSMNPVVLLDEIDKVGS-DYRGDPTAALLEVLDP 447
WP_025413420 493 AQNNSFVDHYLGVPFDLSECLFIATANFPQNIAGPLMDRMEVVEFAGYTEREKAEIAKKYLIPRQLEESGLGDKNVSFTD 572
WP_015894159 461 SQNTTFVDHYLNLPFDLSSTLFICTANNLFDIPGPLRDRMEVIRIAGYTIEEKVEIAQRYLIPRLLEDHGLTESDLHIPE 540
WP_015941610 462 EQNHTFTDHYLNLPFDLSRVLFLATANTWDTVPPALRDRMEVIELSGYIEDEKVQIALSHLVPRQLRANGLRPDEATVSE 541
WP_015804567 452 AQNHTFRDHYLEVELDLSDVVFLATANVLESIPGPLLDRMELVRLDGYTEDEKVTIARDHLLPRQVERAGLEPGDVEVTG 531
WP_015794247 454 AQNHTFRDHYLEVELDLSDVVFLATANVLESIPGPLLDRMELVRLDGYTEDEKVLIGRDHLLPRQIDRAGLSVDEVEFDD 533
WP_012918125 443 AQNHTFRDHYLEVELDLSDVVFLATANVLDSIPAPLLDRMELVQLDGYTEDEKVVIARDHLLPRQLERAGLSAEEVSVED 522
WP_012889934 447 AQNHTFRDHYLEVELDLSDVLFLATANVLESIPGPLLDRMEIVTLDGYTEDEKVAIARDHLLPRQLDKAGLTTEDVTVEE 526
NP_629430    459 AQNHTFRDHYLEVELDLSDVVFLATANVLEAIPEALLDRMELVRLDGYTEDEKVVIARDHLLPRQLERAGLDDDEVTVDE 538
WP_091802026 474 EQNHTFRDHYLEVELDLSDVVFLATANALETIPGPLLDRMELVTLDGYTEHEKVTIGRDHLLPRELERAGFAEGDVTVTD 553
WP_054055109 448 AQNHTFRDHYLEVELDLSDVVFLATANVIESIPAPLLDRMELVRLDGYTEDEKVVIAADHLLPRQLERAGLTAEEVAVDE 527
WP_025413420 573 EAVMKVVSEYTREAGVRQLERQVGAVARKVARRVATGD----S------------------------------------- 611
WP_015894159 541 SVLGFITSRYSREAGLRTFERSIASIMRKRARAKADGD----D------------------------------------- 579
WP_015941610 542 EALRCIINEYTREAGVRNLERSIGAVLRKVARRLSEGEidpaN------------------------------------- 584
WP_015804567 532 AALRRLAGEYTREAGVRQLERSLARVLRKVTAGVALDRa---E------------------------------------- 571
WP_015794247 534 EALRLLAQQYTREAGVRDLERAISRVLRKVAAKTALADs---Eaavkskaavldqdadvaaedapgadaadvevttdvev 610
WP_012918125 523 SALRLLAGEYTREAGVRQLERSISRVLRKVTAKLALGEd--lG------------------------------------- 563
WP_012889934 527 DALRRLAGEYTREAGVRSLERSIARILRKVTANVALGEg---E------------------------------------- 566
NP_629430    539 GALRKLAGEYTREAGVRTLERSIARLLRKVAAQHELGEr---E------------------------------------- 578
WP_091802026 554 AALSRIAAEYTREAGVRDLNRTLAKVLRKVATEVALDKv---A------------------------------------- 593
WP_054055109 528 SALRSLAGEYTREAGVRQLERSIARILRKVTAKLALGEs---V------------------------------------- 567
WP_025413420 612 -----------------------SMLadnKIDAGEVRELLGRPRVHPEKA-----GEQNEVGVATGMYYTPMGGDIMFVE 663
WP_015894159 580 -----------------------TAW---EINAVRTEDILGAPRFPMEEA-----EKEPEIGAVTGLAWTSTGGELMTIE 628
WP_015941610 585 -----------------------LPF---VVDAAFVRTALGRPRFTNETR-----ERIDQPGVAIGLVWTPVGGDIIFVE 633
WP_015804567 572 -----------------------LPV---TVDGGDLEGYLKSPKFTPESA-----ERTAVPGVATGLAVTGAGGDVLFVE 620
WP_015794247 611 tdveataeataeptaepapegpkTKL---TITVENLKDYLGRPRHTPETA-----DRLAVPGVATGLAVTGAGGEVLFVE 682
WP_012918125 564 -----------------------GSV---TIAAENLKGYLGSPKFTPESA-----ERTALPGVATGLAVTGAGGDVLFVE 612
WP_012889934 567 -----------------------LPV---TV--GDLVPYLGRPRHVPESSlpesrQRTAVPGVATGLAVTGAGGDVLYVE 618
NP_629430    579 -----------------------LPF---TVTEGDLRSLIGRPHHVPESAqdpaeRRTAVPGVATGLAVTGAGGDVLYVE 632
WP_091802026 594 -----------------------LPL---VVGDAELESYLGRPRHVPESSlpvnvQRTSIPGVATGLAVTGAGGDVLYVE 647
WP_054055109 568 -----------------------LPL---SVGAADLRGYLGSPKHTPESA-----ERTAVPGVSTGLAVTGAGGDVLFVE 616
WP_025413420 664 AAIR---RltgarrasdsddhtqvsgyGNVSLILTGQLGDVMKESARAALTYAATHASGLQIPEDrLGSIEVHVHVPQGA 740
WP_015894159 629 ALRM---P-------------------GNGKLTVTGQLGDVMRESVDAAYSFVRSRAQALGIEETeFREADLHLHFPAGS 686
WP_015941610 634 ASAV---E-------------------GKKELIITGQLGDVMRESAEAALTYVRSRARSLGIEPSfFENHAIHIHVPAGA 691
WP_015804567 621 AALAepgT-------------------GAGGVVLTGQLGEVMKESAQIALSYLRAHDER----AAtLDGRGVHVHVPAGA 677
WP_015794247 683 ASLSdpeT-------------------GGTGVTLTGQLGDVMKESAQIALSYLRSHGAELELPVAdLSKRAVHVHVPAGA 743
WP_012918125 613 ASLAdkeT-------------------GATGVTLTGQLGDVMKESAQIALSYLRSHGAELGLPVGdLAERNAHIHVPAGA 673
WP_012889934 619 ASLAdpeT-------------------GDTGLTLTGQLGDVMKESAKIALSYLRSRGAELELPVAsLKDRSVHIHFPAGA 679
NP_629430    633 ASLAdpeT-------------------GAAGLTLTGQLGDVMKESAQIALSFLRSHGAELELPVGdLKDRGAHIHFPAGA 693
WP_091802026 648 ASLAdneS-------------------GGSGLTLTGQLGDVMKESARIALSYLRSRGAELELPVGdLRNRGVHVHVPAGA 708
WP_054055109 617 ASLAdkdT-------------------GSAGVTLTGQLGDVMKESAQIALSYLRSHGPELGLPVAeLAERGVHVHVPAGA 677
WP_025413420 741 IPKDGPSAGTGIATAIVSAMSGRPVRRDVAMTGEITLRGRVLPIGGVKEKVLGAHRAGITTIILPKANEADMEDIPDEVR 820
WP_015894159 687 IPKDGPSAGIAVTLALASALSRRPVRRDLALTGEVTLRGRVLEIGGVKEKVLAAYRAGLREVILPKGNEKDVRDVPQEVR 766
WP_015941610 692 VPKDGPSAGITIATALASAATGRLVRDDLAMTGEISLRGRVLPIGGIKEKALGAHRAGIRTIILPKRNIHDLDDLPPKVS 771
WP_015804567 678 VPKDGPSAGVTMVSALASLLSGRPVRSDVAMTGEVSLTGRVLPIGGVKQKLLAAHRAGITTVLLPARNGPDLEEVPRDVR 757
WP_015794247 744 QPKDGPSAGVTMTTALASLLSGRLVRKDVAMTGEVSLTGRVLPIGGVKQKLLAAHQAGATTVLLPKRNGPDLDDVPAEVL 823
WP_012918125 674 VPKDGPSAGVTMTTALASLLSGRPVRSEVAMTGEVSLTGRVLPIGGVKQKLLAAHRAGLTTILIPKRNEPDLEDVPASVL 753
WP_012889934 680 VPKDGPSAGVTLTTALASLLSGRPVRNDVAMTGEVSLTGRVLPIGGVKQKLLAAHRAGITTVLIPARNEPDLDDVPEAVR 759
NP_629430    694 VPKDGPSAGVTMTTALASLLSGRLVRTDVAMTGEVSLTGRVLPIGGVKQKLLAAHRAGITTVIIPKRNEPDLDDVPAQVL 773
WP_091802026 709 VPKDGPSAGVTMTTALASLLTGRLVKADVAMTGEVSLTGRVLPIGGVKQKLLAAHRAGMRTVVIPQRNEPDLDDVPSEIL 788
WP_054055109 678 VPKDGPSAGVTMTTALASLLSGRPVRADVAMTGEVSLTGRVLPIGGVKQKLLAAHRAGITTVVLPKRNEPDLDDVPESVR 757
WP_025413420 821 NVLTFHCVETLDEVFDIALLP-AAKPVQ 847
WP_015894159 767 AKMAFTFANSMDEVLHLALLPhADAHSA 794
WP_015941610 772 TEMTFIPVETLDEVLNIALLP-PGENAP 798
WP_015804567 758 DALTVHLVGDVREVLELALEP-EAVAAA 784
WP_015794247 824 DKLTVHLVGDVREVLDLALEP-AERPVA 850
WP_012918125 754 AELTVHPVSDVREVLDLALVP-AQVDAH 780
WP_012889934 760 SELTVHVVSDVREVLEIALTP-AKVAER 786
NP_629430    774 DKLDVHAVTDVRQVLELALAP-ATNGAE 800
WP_091802026 789 SQLDVRPVSNVRQVLELALEP-ASAPIA 815
WP_054055109 758 EALTVHLVGDVREALDLALEP-VAAQTL 784
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