Conserved Protein Domain Family
DUF4614

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pfam15391: DUF4614 
Domain of unknown function (DUF4614)
This domain family is found in eukaryotes, and is approximately 180 amino acids in length. There is a conserved EALT sequence motif.
Statistics
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PSSM-Id: 464698
Aligned: 27 rows
Threshold Bit Score: 136.712
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_007246256 452 QSHSYSVDDHTLSeeSPKSTGVQYSKSESSlshsRSSPSDSysSDDTITPSKPQSQS---VRRRPVKDATVQTQ---RDA 525
OCA49884     467 ESMHTETSKSIHS--ESDSSASLTSSSRRG----GSSPHGSytNRSKHHQTKRRADK---VQKITIKETWVQTS---EPE 534
XP_005451185 543 RAFSE--ASHSSTsrTSDRSHTSKSNSQGR----SEDSRSSllHEGQASYQQSRRHT---SARKVLKETAVQTH---SGR 610
4_pfamImport   1 ----PDLEHSNTSrrRTQDDYSSTVSGHSQpltkSDDSRSSvsHDGRISSRQSRWPN---SSRKVLKETAVQTQ---HDP 70 
XP_019856021 199 SNTQTVTDREEEEsiKTDNGDLLADYSSDDfeedDDDETLVgsSSNLDASTRPHSLP---RQPDTLKNIGTQTD------ 269
XP_015220961 512 SSFSSPAPQSEVDrkKADLSCRQGVYSRSSasspSASGSGTltPPHETQSP---------HQRKAVKDTAVQTQ---FDG 579
5_pfamImport   8 LKDTESITHDVSSiqEESSKSASSVSSQSEa--sHSVVTPSytETFESDTSRSQSPPvslKRLETKIETAVQTE-----P 80 
XP_001637505 288 SSRSPHSSRSSHSsrSSHSSRSSHSSRSSHhrsnKSNDSNSrsYNRKNESNKHNRNTceiATQTVPEISSMQST------ 361
EEN62869     567 DVSRSDRSRRSKGsrKTDSEDSYSETTRSRtltdSTVSDSRtsRTRSRTPPRKAVKA---------SDVGVQTSvedQLG 637
XP_005989966 619 lSERFEENKRKYSqsFSSHTSSFSSSSSSSlqtsQSTGNQRnrRKSSAQG----------------KEAAVQTE---HAA 679 coelacanth
XP_007246256 526 LTYSWST----GPAVL---GPSIGMSYVDPTPIASHTVSAEAVEALSAYSPAVFALNDMLKQQLALTRSFIESSRYLHHT 598
OCA49884     535 LGYYWPL----GTSDL---RLSSAPVFLEPASIARHAVSPEVIESLTTYSPMALALNDMLKQQLLLTQTFVDMARQLHLS 607
XP_005451185 611 LASTWPT----DIPAV---DPMVSMTYINPSPVVTHTLNAEMVEAISTFNPAVFALNELLKQQLAMTRRFIESSRHLHSS 683
4_pfamImport  71 LAYTWPA------GAL---APPVRMTYMDPTPVGAYTLSAEMVEALSTSNPAVFALNEMLKQQLAMTRRLMESRHRLHSS 141
XP_019856021 270 ----GEReveeKTSFL---LPPVDGGHLNTTPLLPHIVRPEALEVLAGYSPALLAIKDLTNSQLALTRHFIARAQCLSDS 342
XP_015220961 580 LSYSWSN----GMAVL---GPSIGTSHLDPTPVASHVVSADAIEALTAYSPAVFALNDMLKQQLALTRQFIDNTRHLHTS 652
5_pfamImport  81 VDIRSTEnifrGLECSpafPPTL-------------LVSNEALAALTSYSPATLALQDMMKRQLALTRDFIERSERFHKS 147
XP_001637505 362 ----LPQglgvGMAAV---GPQLGMQYVDPSPIATHVVSPEAMEAITAYNPAVVALTDMLRQQIRLVEQFVDANNRMYQA 434
EEN62869     638 LVHQWTAe--sGYAAL---GPQYGAGYTDPTPVATHVVNPDALEAMTSYSPSVLGLNDLLRQQLQLTQQFVTNTRRLHQF 712
XP_005989966 680 FTYSWANd--gGTAVL---GPSHGMMYVDPTPIASHIVSPDAVEALTAYSPAIFALNDMLRNQLLLTKEFVKISSHLHAS 754 coelacanth
XP_007246256 599 MVESLGPADYRYTTLEDTKEFIRCHRA 625
OCA49884     608 TVRSLEAEVYHYTTLEDTKKYIRHQKS 634
XP_005451185 684 LVQSLEPPNYKYTTLEDTKKLIPMHKS 710
4_pfamImport 142 LVQSLGPANYRYTTLEDTKEYIRIHRR 168
XP_019856021 343 ILTSTQPD-HQYVTLDGTQEYIKAHKP 368
XP_015220961 653 LLQSLGPARYRYTTLEDTKEFIQSHKS 679
5_pfamImport 148 AMSSMKPS-YHYTTLEETKKIINAHRK 173
XP_001637505 435 YTSNMNNN-YKYTTLEDTMEFIRRNRP 460
EEN62869     713 YVNSLQAD-HSYTTLQDTLQFIQEHRR 738
XP_005989966 755 VVNSLERDPYHYTTLAEVKQFIRENKA 781 coelacanth
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