Conserved Protein Domain Family
PRK01213

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PRK01213: PRK01213 
phosphoribosylformylglycinamidine synthase subunit PurL
Statistics
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PSSM-Id: 234921
Aligned: 421 rows
Threshold Bit Score: 824.738
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
298491990  18 GIKPEEYAEIVRRLGRHPNKAELGMFGVMWSEHCCYKNSRPLLKQF-----PTTGP--RILVGPGENAGVVDIGN--GLR 88 
15669450    1 -MDENDLKYIEKVLGRKPNHIELAMFENLWSEHCAYRTSKKLLRMFaktvnEKTSK--NIVVGIGDDAAVIRLKN--DIC 75 
150401881   1 -MDLNDLKFIEEQLGRKPNDVEIGMFENLWSEHCSYRSTKKLLSMFg----KTVKEnqNIVVGPGDDAALIKIDDetDLC 75 
256810000   1 -MDENDLRYIEKVLGRKPNHIELAMFENLWSEHCAYRTSKKLLRMFaktvnEKTSK--HIVVGIGDDAAVIRLKD--DIC 75 
261402801   1 -MDENDIKYIENTLGRKLNDIELAMFENLWSEHCAYRTSKKLLRMFaktvnEKTSK--NIVVGIGDDAAIIRLKD--DIC 75 
289192150   1 -MDENDLKYIEKVLGRKPNHVELAMFENLWSEHCAYRTSKKLLRMFaktvnEKTSK--NIVVGIGDDAAVIRLKD--DIC 75 
294494948   1 MLPEDDLKIIVEKMGRQPNDVEQGCFLNLWSEHCSYRSSAPLLKSF-----TTTGD--RVIIGPGDDAAIVRFGD--GWV 71 
296109179   1 -MDENDLKYIQKTLGREINEIEKAMFENLWSEHCSYRTSKKLLRMFsktinERTSK--DIVVGIGDDAAVIRLKD--NIC 75 
298676042   1 MLPENDLKIITEKMGRKPNLVEQGCFLNLWSEHCSYRSSAPLLKTF-----TSTGE--KVVIGPGDDAAIIQFDD--EWV 71 
91773985    1 MLPENDLKIITEEMGREPNLVEQGCFLNLWSEHCSYRSSAPLLKTF-----TTVGD--RVIIGPGDDAAIIRFGE--GWV 71 
298491990  89 LAFKIESHNHPSAVEPFQGAATGVGGILRDIFTMGARPIALLNSLRFGD---L---DDAKTQRLFTGAVAGISYYGNCVG 162
15669450   76 LAIAMESHNHPSYIDPYNGAATGVGGIVRDVLSMGAKPIALLDPLRFGD---IfgkEGDKVRWLIEGVVKGIGDYGNRIG 152
150401881  76 VAMAMESHNHPSYIDPYNGAATGVGGIVRDIISMNAKPIALLNALRFGD---IngeEKDKVRWLVEGVVDGIRDYGNRIG 152
256810000  76 LAIAMESHNHPSYIDPYNGAATGVGGIVRDVLSMGAKPIALLDPLRFGD---IfgkEGDKVRWLVEGVVKGIGDYGNRIG 152
261402801  76 LAIAMESHNHPSYIDPYNGAATGVGGIVRDVLSMGAKPIALLDPLRFGD---IfgkEGDKVRWLIDGVVRGIGDYGNRIG 152
289192150  76 LAIAMESHNHPSYIDPYNGAATGVGGIVRDVLSMGAKPIALLDPLRFGDifgKe--GD-KVRWLIEGVVKGIGDYGNRIG 152
294494948  72 LALGMESHNHPSYVDPYNGSATGVGGIVRDIISMGARPIALMDPLYFGP---L---NTPKNLYLFEHIIEGIGGYGNCIG 145
296109179  76 LALAMESHNHPSYIDPYNGAATGVGGIVRDVLSMGAKPIALLDPLRFGDprvE------KVRWLIDGVVRGIGDYGNRIG 149
298676042  72 LALGMESHNHPSYVDPYNGAATGVGGIVRDILSMGARPIALMDPLYFGP---L---NNSKNLYLFEHIIEGIAGYGNCIG 145
91773985   72 LAIGMESHNHPSYVDPYNGSATGVGGIVRDIISMGARPIALMDPLYFGP---L---NTPKNLYLFEHIIEGIAGYGNCIG 145
298491990 163 VPTVGGEVYFDSAYSGNPLVNVMALGLMETEDIVKSGASGFGNPVLYVGSTTGRDGMGGASFASTELTD-QSMDDRPAVQ 241
15669450  153 VPTVGGECEFDSSFDYNNLVNVVCVGLVKENEIITGKAKEPGLSLILIGS-TGRDGIGGASFASKDLTE-ESEEERPSVQ 230
150401881 153 VPNVGGECEFDKSYDYNNLVNVVCIGLVKEGDIVTGKAKETDLTLILVGS-TGRDGIGGASFASKDLTS-ESEGDRPSVQ 230
256810000 153 VPTVGGECEFDSSFDYNNLVNVVCVGLVRENEIITGKAKEPGLSLILVGS-TGRDGIGGASFASKDLTE-ESEEERPSVQ 230
261402801 153 VPTVGGECEFDSSFDYNNLVNVVCVGLVKENEIITGKAKEPGLSLILVGS-TGRDGIGGASFASKDLTE-ESEEDRPSVQ 230
289192150 153 VPTVGGECEFDSSFDYNNLVNVVCVGLVKENEIITGKAKEPGLSLILVGS-TGRDGIGGASFASKDLTE-ESEEERPSVQ 230
294494948 146 VPVVRGEAFFDESYSGNPLVNVVCVGLAREDQLVTATAQKAGNKIILIGSTTGRDGLGGASFASRDLSEsAEAEDRPSIQ 225
296109179 150 VPTVGGECEFDESFNYNNLVNVVCVGLVKEEDIVRGKTKEKELSLILVGS-TGRDGIGGASFASKDLTE-ESEEERPSVQ 227
298676042 146 VPVVRGEAFFDDSYSGNPLVNVVCIGLAHKENLITAKAEKAGNKLVLMGATTGRDGLGGASFASRDLSEeAESEERPSIQ 225
91773985  146 VPVVRGETYFDESYSGNPLVNVVCVGLAREENIVTACAQKAGNKLVLIGSTTGRDGLGGASFASRDLSEeAEAEDRPSIQ 225
298491990 242 VGDPFLEKSLIEACLEAFKTGAVVAAQDMGAAGITCSTSEMAAKGSVGIEFDLDKIPARELGMIPYEYLLSESQERMLFV 321
15669450  231 VGDAFSEKCLIDAVLEAVKTGKVKAMKDLGAAGLSGASSEMCYGGGVGCELYLENVVLREP-LTPYEIMVSESQERMLLA 309
150401881 231 IGDAFTEKCVIDSTLEACATKKVKAIKDLGAAGITSSCSELCYSGGVGAELYLENVILRDEGMTAYEIMVSESQERMLLA 310
256810000 231 VGDAFSEKCLIDAVLEAIKTGKIKAMKDLGAAGLSGASSEMCYGGGVGCELYLENVVLREP-LTPYEIMVSESQERMLLA 309
261402801 231 VGDAFSEKCLIDAVLEAVKTGKVKAMKDLGAAGLSGASSEMCYGGGVGCELYLENVILREP-LTPYEIMISESQERMLLA 309
289192150 231 VGDAFSEKCLIDAVLEAVKTGKVKAMKDLGAAGLSGASSEMCYGGGVGSELYLENVVLREP-LTPYEIMVSESQERMLLA 309
294494948 226 IGDPFTEKLLIELSLEAVAEGVVKSCRDLGAAGLAGASSEMASKGDLGIHIIADRVAQREAGMNAFEIMIAESQERILFE 305
296109179 228 VGDAFSEKCLIDAILEAVKTKKVKAMKDLGAAGLSGAATEMCLS---GCELYLENVPLREP-LTPYEIMVSESQERMLLA 303
298676042 226 IGDPFTEKLLIEATLEGIDKGYVKSCRDLGAAGIVGASSEMASKGNLGAYMYLDNVVLRESGMKPFEILIAESQERILLE 305
91773985  226 IGDPFTEKLAIEATLEAIGAGYVLSCRDLGAAGLAGASSEMASKGKLGMRLEADKVILREDGMTPYEIMIAESQERILME 305
298491990 322 AHKGREKELIDIFHRWGLQAVVAGTVIAEPIVRILFQGKVAAEIPADALAENTPLYERELLTNPP---QYALEawawtvd 398
15669450  310 VEPGSEEEIIEIFKKYELPASVIGKTIPEKRIIAKYKGEVVVDLPLDLLC-EAPLYDREGKEDLK---EKEDD------- 378
150401881 311 VEKGSEEEIIKIFEKYELPVSIIGKTTDTKRFFVKMNDEVVVDLPLDLLC-EATLTDSEEKETIL---ETPDNk------ 380
256810000 310 VESGSEEEVIKIFKKYELPASVIGKTIEEKRIIAKYNGEVVVDLPLDLLC-EAPLYDREAKEDLK---EREDD------- 378
261402801 310 VEPGSEEEIIEIFKKYELPASVIGKTIKEKKIIAKYNEEEVVNLPLDLLC-EAPLYDREAKEDLK---EKEDD------- 378
289192150 310 VEPGSEEEIIEIFKKYELPAAVIGKTIKEKRIIAKYKGEVVVDLPLDLLC-EAPLYDREAKEDLK---EKEDD------- 378
294494948 306 VEPENVDYMLQLAEKYDLNGAVIGELTERPYFTVDFEGNTETDIPIHLLTEGAPTFERPSTPFTV---KKDPV------- 375
296109179 304 VEKGSEEEIIKIFEKYDLPAAVIGRTTDTGRIIAKYKGEVVVDLPISLLC-NAPLYDREEEERIL---EKEGRi------ 373
298676042 306 VEPENVDYMLDVAEKYELSASVIGELKNDQKYTAEFGDEIVADMPVKLLTEGCPTFERPATPPSSqniGAKPEf------ 379
91773985  306 VEPENVDAVLAIGKKYDLHASMIGELTERLYYTVEFEGEMVADIPVMLLTEGAPTFERPSTAPPE---REIGEk------ 376
298491990 399 slpacDAt-----GietgriwkSWNEILLILLNTPTIASKSWVYRQYDHQVQNNTVLLPGGaDAAVLRLrpledilnltt 473
15669450  379 -----KEkik-mpE--------DLNAVLLKLLESPNICSKEWIYQQYDHEVQIRTVVKPGK-DAAVLRIn---------e 434
150401881 381 -----ENiaepepA--------ELNNILLKLLKSPNINSKKWIYEQYDHEVQLNTVVRPGK-DASVLRLke--------- 437
256810000 379 -----KEkik-mpE--------DLNAVLLKLLESPNICSKEWIYQQYDHEVQIRTVIKPGK-DVAVLRIm---------e 434
261402801 379 -----KEkik-mpE--------DLNAVLLKLLESPNICSKEWIYQQYDHEVQIRTIIKPGK-DAAVLRIl---------e 434
289192150 379 -----KEkik-mpE--------DLNDVLLKLLESPNICSKEWIYQQYDHEVQIRTVVKPGK-DAAVLRIte-------vy 436
294494948 376 -----PDa-----Tg-------DLKQAILDVLASHNVASKEWIYRQYDHEVQIRTVAKPGS-DSAIQRIvg--------- 428
296109179 374 -----EEr-----V--------DLEEAILKLLESPNICSKEWIYSQYDYDVQLRTVIKPGR-DAAVLRIl---------- 424
298676042 380 -----PY---------------DLKTTVLDVVSSYNTTSKDWIYSQYDHEVQIRTAVNPGD-DSGVLRIsg--------- 429
91773985  377 -----PDl-----Pa-------DMKKVVLDILSSHNIASKEWIYRQYDHEVQVRTVEKPGS-DAAVLRIgd--------- 429
298491990 474 KaenlKSGVAATVDCNSRYVYLDPYEGAKAVVAEAARNLSCVGAEPLAVTDNLNFGSPEKPIGYWQLASACQGLSEGCQE 553
15669450  435 Vy---PMGIALTTDCNSRYCKLNPYVGAVNAVAEAVRNLATVGAEPIAMLDNLNFGNPERPERFWQLAECIKGLADAAEF 511
150401881 438 ---ahPKALALVADCNPTYCKLNPYGGSLNLVCESVRNLATVGAKPIGMLDNLNFGNPEKPERFYQIKKCIEGLADGAEI 514
256810000 435 Ty---PTGIALTTDCNSRYCKLNPYVGAVNAVAEAVRNLATVGAEPIAMLDNLNFGNPERSERFWQLAECIKGLSDAAEF 511
261402801 435 Ty---PTGIALTTDCNSRYCKLNPYVGALNAVAEAVRNLATVGAEPMAMLDNLNFGNPERAERFWQLAECIKGLADAAEF 511
289192150 437 P-----MGIALTTDCNSRYCKLNPYVGAVNAVAEAVRNLATVGAEPIAMLDNLNFGNPERPERFWQLAECIKGLADAAEF 511
294494948 429 -----dRGIALSCGCNPRHTYLDPYEGGKGTLAENAMNLAVKGGRGLALLDCLNFGNPEKPDIYWQFKYAINGLADAARE 503
296109179 425 Et--yPVGIALTVDCNSRFCKLNPYVGSLYTVAEAVRNLACVGAKPLAMLDNLNFANPEKPDRFWQLKECIRGLADAAFS 502
298676042 430 -----nKGLVVSCGCNPRHTLLDPYKGGRGTVFENAMNLAVKGGKAIAMVDCLNFGNPEKSDIYWQFKQAILGLGDCARE 504
91773985  430 -----gKGLAMSCGCNPRHTLLDPYEGGKGTLIENSMNLAVKGAEGIALVDCLNFGNPERPDIYWQFKQAILGLGDAARS 504
298491990 554 FSTPVTGGNVSLYNETldsQg--nPQPIYPTPVVGMVGLIEDLTKICGQGL---Qsp----gDLIYLLGidvksrspqpp 624
15669450  512 FEIPVVGGNVSLYNETvie---gkEHPINPTPAIFVLGKVEDVEKVPGVLDnkiKe-----gDILIITN----------- 572
150401881 515 IGVPVVGGNVSLYNETvid---gkDYPINPTPVISIVGTIENINNIPKGAKe---------gDILIITA----------- 571
256810000 512 FEIPVVGGNVSLYNETvie---gkEFPINPTPAIFVLGKVEDVEKVPGVLDnkiRe-----gDMLIITN----------- 572
261402801 512 FEIPVVGGNVSLYNETvie---gkEFPINPTPAIFVLGKVEDVEKVPGVLGnkiKd-----gDVLIITN----------- 572
289192150 512 FEIPVVGGNVSLYNET---IiegkeHPINPTPAIFVLGKVEDVEKVPGV-----LdnkikegDILIITN----------- 572
294494948 504 LSIPVVGGNVSLYNESe-eH----QTSILPTPAIGVVGEVEDVSTVPSSQFt--Gt-----gQSVILVG----------- 560
296109179 503 FDIPVVGGNVSLYNETvie---gkEYPINPTPAIALIGKIDNIEKVPGVLDnkvEe-----gDILIITN----------- 563
298676042 505 LSIPVVGGNVSLYNESe-eR----GTAIAPTPSIGLIGITDDVAQVPPSYFv--Ne-----gETIILVG----------- 561
91773985  505 LSIPVVGGNVSLYNES---Ge--yGTAIAPTPSIGLIGITGELETVPQSHFa--Ge-----gNTIILVG----------- 561
298491990 625 lergaeISkiELGASEYLATIHNTIAGKPPRVDFDLERRVQKVCREGIRAGWVRSAHDTAEGGLTVALAECCLSGHLGAE 704
15669450  573 ------ETkdEMGGSEYYKVIHNTEEGRVPRVDLEKEKKIYEEVREVVKEGLVSEAVDCSRGGLAVALAKMAVLNNIGLE 646
150401881 572 ------PTkdEMGGTEYYKQIHNTEEGIVPKANLEVEKEIYSKVCELVNNGLINEAVDCSKGGLGVAISKLCMTNNIGVE 645
256810000 573 ------ETkdEMGGSEYYKVIHNTEEGRVPRVDLDKEKKIYEEVREVIKEGLVSEAVDCSRGGLAVALAKMAILNNIGLD 646
261402801 573 ------ETrdEMGGSEYYKVIHNTEEGIVPRVDLEKEKKIYKEIREIIKEGLVSEAVDCSRGGLAIALAKMAVLNNIGLD 646
289192150 573 ------ETkdEMGGSEYYKVIHNTEEGRVPRVDLEKEKKIYEEVREVVKEGLVSEAVDCSRGGLAVALAKMAILNNIGLD 646
294494948 561 ------TTkaELGGSEYYNVRRTPNAGDVPQVPADM-VDIVESLITTIREGKVSVSHDISHGGLAAALCEM--CGNVGLE 631
296109179 564 ------ETkeEMGGSEYYKVLFNSEIGRVPRVNLEKEKEIYKKVVSLINRGLISGTKDCSRGGLGIALAKFCINNNIGVE 637
298676042 562 ------EThdELGGSEYYNRIGYRTHGNTPDVPDNAESILDGVRKAVISSK-VSSAHDVSQGGLVVALCEMCDr--IGAD 632
91773985  562 ------NTldEMGGSEYYNMVGLRLNGNVPKVTDES-VKVVETLINVVRDGNVVAAHDVSAGGLAVALSEMCD--SIGAE 632
298491990 705 INLG----ISATHdlrfDEVLFGEGGARILVSVS----EEHLEVWESYlqeYLPENWQkLGVVSNSELGLQICTNDnhdl 776
15669450  647 VDLTeynkNNLRD----DILLFSETSGRIILAVR----DENKDKVLSK-----LSSAYiIGKVGGSRLKIKINEKDvvn- 712
150401881 646 LDLGdyntNGLRN----DILLFSESSGRIILSVDknnaDKVVKELNGA---------I-IGTVKGNELKIKLNDNEli-- 709
256810000 647 VDLTtynkNNLRD----DILLFSETSGRIILAVReenkDKVLSKLSNA---------YvIGKVGGNKLKIKINGKDvid- 712
261402801 647 VDLTsynkNNLRD----DVLLFSETSGRIILAVR----EENKDKVLNK-----LSSAHvIGKVGGNRLKIKVNGRGiid- 712
289192150 647 VDLTsynkNNLRE----DVLLFSETSGRIILAVR----EENKDKVLSK----LSNAHI-IGKVGGNRLKININGKEiid- 712
294494948 632 VDLSei-aGDMST----EAVLFSESHGRALLATD-----DPHVVSAQL---GNIPHIV-VGTTGGDSVRITVNTDHie-- 695
296109179 638 VELDnyniNKLRE----DLLLFSETSGRIILAVKeenlNEVLKEIDGY---------V-IGRVGGKELSIKINNNKis-- 701
298676042 633 VNLNsv-gAGLRT----DEILFSESHARAIISTS-----EPVYVRQML---ADIQHVI-IGSTGGQMLDITHNDQEiv-- 696
91773985  633 IDLTsv-gDNLRA----DDVLFSESHARAILVTS-----SPEKVKEML---ADVPHTV-IGTVGGNNLSIKGNGFDls-- 696
298491990 777 ikvSIQEMSERYDLAISNRLaI 798
15669450  713 -ldV-EEMKKRYYEAFPKMMgE 732
150401881 710 -nlPIEEMKNKYENAFSEMMgE 730
256810000 713 -ldV-EEMKKRYYEAFPKMMgE 732
261402801 713 -ldV-NTMKKRYYEAFPKMMgE 732
289192150 713 -ldV-NEMKKRYYEAFPKMMgE 732
294494948 696 --vGLDEIKDARASLTRLMMe- 714
296109179 702 --iSLGEMKKVYKEAFPKMMgE 721
298676042 697 --lTLDEISNS-RSSLKRLMtE 715
91773985  697 --lSLEEISDARASLTKMMMe- 715
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