3RPH,3K5W


Conserved Protein Domain Family
yjeF_cterm
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TIGR00196: yjeF_cterm 
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yjeF C-terminal region, hydroxyethylthiazole kinase-related
E. coli yjeF has full-length orthologs in a number of species, all of unknown function. However, yeast YNL200C is homologous and corresponds to the N-terminal region while yeast YKL151C and B. subtilis yxkO correspond to this C-terminal region only. The present model may hit hydroxyethylthiazole kinase, an enzyme associated with thiamine biosynthesis. [Unknown function, General]
Links
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Statistics
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PSSM-Id: 272955
Aligned: 10 rows
Threshold Bit Score: 296.603
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3RPH_A         7 PFWTEEHVRATLPE-RDA-ESHKGTYG-TALLLAGSDDMPGAALLAGLGAMRSGLGKLVIGTSENVIPLIVPVLPEATYW 83  Bacillus subtilis
P31806       231 QRFSAEQLSHWLKP-RRP-TSHKGDHG-RLVIIGGDHGTAGAIRMTGEAALRAGAGLVRVLTRSENIAPLLTARPELMVH 307 Escherichia col...
Q58981       229 EYIVGWGDLKALRK-RDS-NSHKGQNG-KVLIIGGSKDFYGAPILAGLAALKI-VDLVGILSVGKVIDKVN--HPEFIMY 302 Methanocaldococ...
P94368         4 PFWTEEHVRATLPE-RDA-ESHKGTYG-TALLLAGSDDMPGAALLAGLGAMRSGLGKLVIGTSENVIPLIVPVLPEATYW 80  Bacillus subtil...
P74217       227 QVLGADQAQQTLPLsRPL-VTHKYQQG-HLLLICGSQQYAGGALLTTLGARASGVGMVTVAVPMGIKALLHSQCPEVLVK 304 Synechocystis s...
P56176       211 DTFLLEKSDLKLPLrDRK-NAHKGDYG-HAHVLLGK--HSGAGLLSALSALSFGSGVVSVQALECEITSNN--KPLELVF 284 Helicobacter py...
AIG97727     192 ENLCGPGDVAFSYK-RYE-DAHKGVHG-KVLVVGGG-DYTGAPALASLAALYAGADIVTTAVPMAIRKVVASFSPNLIVR 267 Archaeoglobus f...
WP_010876880 232 EIFMGPGDLLRIPS-RRP-GSHKGENG-RVLIIGGSRQYSGAPAIAAKAALRAGADIVMVAAPGSAARAIRSLSPDLIVR 308 Methanothermoba...
P36059         8 RELIKLAQKRCIPP-LLP-KFHKGQSGgRVCIIGGCEDYTGAPYFSANATALMGCDLTHVICEYNAGTVIKSYTPNLMVH 85  Saccharomyces c...
3K5W_A       212 DTFLLEKSDLKLPL-RDKkNAHKGDYG-HAHVLLGK--HSGAGLLSALSALSFGSGVVSVQALECEITSNN--KPLELVF 285 Helicobacter py...

3RPH_A        84 RDg------wKKAADAQ------LEETYRAIAIGPGLPQTES----VQQAVDHVLTADC---PVILDAGALAKRTYP--- 141 Bacillus subtilis
P31806       308 EL--------TMDSLTE------SLEWADVVVIGPGLGQQEW----GKKALQKVENFRK---PMLWDADALNLLAINp-- 364 Escherichia col...
Q58981       303 RVegdylssqHVDYTLE------IAKKYDVVVLGNGLGANNRt---KAFLNEFLAKYDG---KVVIDADAIKVIDYNn-- 368 Methanocaldococ...
P94368        81 RDg------wKKAADAQ------LEETYRAIAIGPGLPQTES----VQQAVDHVLTADC---PVILDAGALAKRTYP--- 138 Bacillus subtil...
P74217       305 GLletp-sgaIAGLGNL------DLSRYSAVALGPGLGSDVG-----P-LVEEVLSVNC---PLILDADGLNQLAQQqll 368 Synechocystis s...
P56176       285 CEn--------------------FPNLLSAFALGMGLENIPK-------DFNKWLELA----PCVLDAGVFYHKEVLq-- 331 Helicobacter py...
AIG97727     268 GVgeeriemkNLEELEE------LVKRHDVVVAGMGVGENPE----FKEVVEELLKSCK---KAVLDAQGI---VDSv-- 329 Archaeoglobus f...
WP_010876880 309 ELeggyigmeSLDEILE------LAEKADSVLMGCGAGRETStartFMRAIEDLHEMEK---PIVLDADALRLMDYSd-- 377 Methanothermoba...
P36059        86 PYlrmsntklDVDMDEQrkkinsLLDRIHVVVIGPGLGRDPLmlksIKDIIRYILEKHEgkiPLVIDADGLFLVTQDsev 165 Saccharomyces c...
3K5W_A       286 CEn--------------------FPNLLSAFALGXGLENIP-------KDFNRWLELA----PCVLDAGVFYHKEILq-- 332 Helicobacter py...

3RPH_A       142 ------KREGPVILTPHPGEFFRMTG------VpvNELQKKR---AEYAKEWAAQLQTVIVLKGNQTVIAFPD--GDCWL 204 Bacillus subtilis
P31806       365 ------DKRHNRVITPHPGEAARLLGc----sV--AEIESDR---LHCAKRLVQRYGGVAVLKGAGTVVAAHP--DALGI 427 Escherichia col...
Q58981       369 -----fEFSENYIFTPHKREFE--------------YMGIDL-------D-NIENIKSTIVLKGKYDIIFNA---NNLKI 418 Methanocaldococ...
P94368       139 ------KREGPVILTPHPGEFFRMTGv----pV--NELQKKR---AEYAKEWAAQLQTVIVLKGNQTVIAFPD--GDCWL 201 Bacillus subtil...
P74217       369 p--llaVRTAPTVLTPHGGEFKRLFP---------DIDQGDR---LTAVQTAAAMCQATVLLKGAKTVIASPT--GPTWA 432 Synechocystis s...
P56176       332 ------ALEKEVILTPHPKEFLSLLKlvginiS--MLELLDNk--LEIARDFSQKYPKVVLLLKGANTLIAHQ--GQVFI 399 Helicobacter py...
AIG97727     330 ------PENCECILTPHRGEFG--------------RVFGDT-----EVQKAALKAKAVILLKGREDVITDG---SRVKV 381 Archaeoglobus f...
WP_010876880 378 -----vSEYRELTVTPHMAEFSSFFk-----lK--SMIFNDFresVSAFQSISSRIRGTVLLKGRIDMIFQG---DRLRL 442 Methanothermoba...
P36059       166 kemlksYPKGRVILTPNVVEFKRLCD------A--IGKKGDSh--SEMGSLIAQELNCIVVEKGQSDKIFSPDseKDMLT 235 Saccharomyces c...
3K5W_A       333 ------aLEKEAVLTPHPKEFLSLLNlvginiS--XLELLDNk--LEIARDFSQKYPKVVLLLKGANTLIAHQ--GQVFI 400 Helicobacter py...

3RPH_A       205 NPTGNGALAKGGTGDTLTGMILGMLCCH--EDPKHAVLNAVYLHGACA-ELWTDEHSAHTLLAHELSDILPRVWKR 277 Bacillus subtilis
P31806       428 IDAGNAGMASGGMGDVLSGIIGALLGQK--LSPYDAACAGCVAHGAAA-DVLAARFGTRGMLATDLFSTLQRIVNP 500 Escherichia coli K-12
Q58981       419 NKTGNAGLTKGGTGDVLAGLIGALFAV---NEAFLSACCGAFINGYAG-DLLLKEKG-YYYTPLDLIEKIPNVLKI 489 Methanocaldococcus ...
P94368       202 NPTGNGALAKGGTGDTLTGMILGMLCCH--EDPKHAVLNAVYLHGACA-ELWTDEHSAHTLLAHELSDILPRVWKR 274 Bacillus subtilis s...
P74217       433 IKDSTPALARGGSGDVLTGLMGGILAQPekFDLAQRVATAAWWHAQAG-ILASQQRTILGVDAQHLAEYLIPACRQ 507 Synechocystis sp. P...
P56176       400 NILGSVALAKAGSGDVLAGLILSLLSQN--YTPLDAAINASSAHALAS-LEFKNNYA---LTPLDLIEKIKQL--- 466 Helicobacter pylori...
AIG97727     382 NRSGNAGMTVGGTGDVLAGIAAAFLCN---DDAFHSACAAAFLNGLAG-DVCFEKFG-YNYTATDLVKAIPEAILR 452 Archaeoglobus fulgi...
WP_010876880 443 NKTGCPGMTVGGTGDALAGLTAGLRALG--LSSFDSASLAAFINGMAG-ELAMERHG-NGFTASDMVDMIPSVMDP 514 Methanothermobacter...
P36059       236 NSEEGSNKRVGGQGDTLTGAISCMLAFS--RAMYDFKICEQEEKGESSnDKPLKNWVDYAMLSCYAGCTITRECSR 309 Saccharomyces cerev...
3K5W_A       401 NILGSVALAKAGSGDVLAGLILSLLSQN--YTPLDAAINASLAHALAS-LEFKNN---YALTPLDLIEKIKQLegh 470 Helicobacter pylori
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