Conserved Protein Domain Family
ST7

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pfam04184: ST7 
ST7 protein
The ST7 (for suppression of tumorigenicity 7) protein is thought to be a tumour suppressor gene. The molecular function of this protein is uncertain.
Statistics
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PSSM-Id: 461214
Aligned: 7 rows
Threshold Bit Score: 857.951
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003220504  39 AGPWAR--SLGLVAALGLLYCLRGPLRLRDNLAAVTV--FLSTLTPKFYVALTGTSSLISGLIFIFEWWYFRKYGTSFIE 114
XP_030856337  17 AWIWVYlwVIWLLLVGVLVYILRSPLKVMENVNVVAM--FLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIE 94 
XP_017946694  23 SRCWAYgcLIFMVFSAVTLYYFRVPLRLYDNLAAVVV--FINTLTPKFYVALTGTSSVISGLILVFEWCYFKKYGTSFIE 100
A7S641        24 GWSWTYlwGFWFLLVIFLLYILRAPLRLKENMNLVIL--FLNTLTPKFYVALTGTSSFISGIILIFEWWYFRKYGTSFIE 101 starlet sea ane...
XP_001949568   7 GWIWRKlwWAWYLAIILVVCYTRECLRKKAIWDVVAV--FMDSLTPKFYIALTATSSFISALIMILEWIYFQKYGVSFIE 84 
Q19337         2 ACSWTFlwLLWIALVAVLLFALRGPLKISESLESVTAtsYFNNLTPKFYVALTGTSSLVSGIILIFEWWYFKN------- 74  Caenorhabditis ...
XP_018668463  32 swSWGYlwGIWLLLVAILVYFLRAPLKLSDNINAMSV--FISSLTPKFYVALTGTSSLLSGIILIFEWWYFRKYGTSFIE 109 vase tunicate
XP_003220504 115 QVSVSHLRPLIGGTENtispqttfsatnGENEMNRQSLSECKVWRNPLNLFRGAEYSRYTWVTGKEPLTYYDMNLSAQDH 194
XP_030856337  95 QVSLNHLSPWLGGAENg-----------GGTSTGQQSPPECKTWRNPLNLIRGAEYNRYNWVTGKDPLTYYDMNQSAQDH 163
XP_017946694 101 QVSVNHLRPLMGGTEPasssvg-ffpsigENEPSRQPLSDCKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDH 179
A7S641       102 HISLAHLGPLIGGGDNta-------------pnSSQNVAECKVWRNPMNLFRGAEYSRYLWVTGREPLTYYDMNLSAQDH 168 starlet sea ane...
XP_001949568  85 QFSLNYISPWIGGGND-----------------NNQQVPECKVWRNPLGLFRGAEYSRYLNYTKREPLTFYDMNLSAQDH 147
Q19337        75 -------NAGIDAGDEegs-------dnDESIENTKTVPECKVWRNPMALFRAAEYNRFRKETNSEPLTYYDMNLSAQDH 140 Caenorhabditis ...
XP_018668463 110 QVSVNHLGPLLGGEDNet--------tsTQANDSKQ---KCKVWRNPLNLLRGSEYNRYNWVTGQEALTYYDMNLSAQDH 178 vase tunicate
XP_003220504 195 QTFFTCETD--SLRPSDSVMQKAWRERNPQARIKAAYQALEINNDCAMAYVLLAEEEAITIVDAEKYFKQALRAGETIYR 272
XP_030856337 164 QTLFTCDSD--PTRHQDEVMMKAWRERNPQNRIKAAHEALEKSGDCATALVLLAEEEATTIVDAEKKFRQALKIAEANFK 241
XP_017946694 180 QTFFTCDTD--SLRPSDSVMQKAWRERSPQARIKAAYQALNVYNDCATAYVLLAEEEAATISDAEIFFQQALKAGESAYR 257
A7S641       169 QTFFTCDADetSSNSADTIMLTAWRERDQEKRINAACRAYECDPTSPTALILLAEEKAQTITEAEWYLKQALKTSDDLIR 248 starlet sea ane...
XP_001949568 148 QAFFICDAD--NGKPDYEIMQAAWRERVPAARVKAAHLALEKNADCVTALIMLAEEEAPTMLKVEKILRKALKLAEANYK 225
Q19337       141 QSLFMCDED--QGRAEYEIMQVAWRERESEERIQTARAALAINPECASALVLLAEEESETVSQAENLLRRALRAIESTLN 218 Caenorhabditis ...
XP_018668463 179 QTFFTCETD--NIRPADNVMQKAWRERNPQARIKAAHQALDLDQDCATGYILLAEEEAVTILEAERLFRRALKAGEGLYR 256 vase tunicate
XP_003220504 273 --KSQHCSTQSPQHEAQLRRDTNVLVYVKRRLAMCARKLGRIKEAVKMMRDLMKEF-PLLSVLNIHENLLEALLELQAYA 349
XP_030856337 242 --RSQALQHHSPPHEKIHRRDLNVLVYIKRRIAMCMRKLGRTKEAVKMMRDLIKEF-PVVSMFQIHENLIEALLEMQLYA 318
XP_017946694 258 --KSQQQQHLSSQHEAQHRRDTNVLIYTKRRLAMCARRLGRVREAVKIMRDLMKEF-PILSMVNIHENLLEALLELQAYA 334
A7S641       249 ---NGASTNGDGKEDTIHRKNTNVCVYIRRRLAMCARKLGRTKEAIKMMRDLMKEF-PLMSVLNIHENLIEALLEVQAYS 324 starlet sea ane...
XP_001949568 226 --RTQKSHHLDSNIEMQHRRDLNVLIYIKRRIAMCCRKLRKLKEAVKMFRDLSKEMpPIMNILNVHENLIEVLLETQSYA 303
Q19337       219 sySNNQIASYAQNGDAVRKRDLTIQTYIKRRLAMCARKQGRLREAIKGFRDLSRDQ-SLSTLLSVQDNLIEACLEVQAYA 297 Caenorhabditis ...
XP_018668463 257 --KSQLLQHHSAMHEAEHRRDTNVLVYIKRRLSMCARKLGKTREAVKMMRDLMKEF-PMLNVLNIHENLLEALLELQAYA 333 vase tunicate
XP_003220504 350 DVQAVLAKYD--------DISLPKSAAICYTAALLKARAVSDRF----SPETASRRGLSTAEISAVEAIHRAVEFNPHVP 417
XP_030856337 319 DVQALLAKYD--------DISLPKSATICYTAALLKARTVCDKF----SPEMASKRGLSTAEMNAVEAIHRAVEFNPHVP 386
XP_017946694 335 DVHAVLSKYD--------DISLPKSATICYTAALLKARAVSESYvfrfSPESASRRGLSTSEMNAVEAIHRAVEFNPHVP 406
A7S641       325 EVQQVLAKYD--------DITLPKSATICYTAALLKARAVCDKF----SPEVAAKRGLSPAEMAAVEAIHRAVEFNPHVP 392 starlet sea ane...
XP_001949568 304 DVQSVLAKYD--------DINLPKSAVICYTSALLKIRVIADKY----NVGNTLKKGLTQAEEVALEAIHRAVEFNPHVP 371
Q19337       298 DVQNLLVRYDgygapcsyELREPRSAAMSYTSALLKVRAVAENFr--cAADSSIRRGLSSAEQTAIEALTRAMEFNPHVP 375 Caenorhabditis ...
XP_018668463 334 DAQALLFKYD--------DISLPKSATICYTAALLKARAVCDKF----SLEVATKRGLSSSEMTAVEAIHRAVEFNPHVP 401 vase tunicate
XP_003220504 418 KYLLEMKSLILPPEHILKRGDSEAVAYAFFHLQHWKRIEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPSCTETADREL 497
XP_030856337 387 KYLLEMKSLILPPEHILKRGDSEAIAYSFLHIAHWKRVEGALQLLHCTWEGTFRMIPYPLEKGHLFYPYPSCTETVDREL 466
XP_017946694 407 KYLLEMKSLVMPPEHILKRGDSEAVAYAFFHLQHWKRVEGALNLLQCTWEGTFRIIPYPLEKGHLFYPYPGCTENVDREL 486
A7S641       393 KYLLEQKSLILPPEHILKRGDSEAVAYAFYHLPHWKQVEGAINLLHCTWEGTFRLVPYPLEKGHLFHPYPGCTENADREL 472 starlet sea ane...
XP_001949568 372 KYLLEMKSYIFPPEHILKRGDSEAVAYAFFHLAHWKRIKGALAVLNVTWESAFNQIPYPLEKGYLFHPYPTCTELADREL 451
Q19337       376 PYLLELRSMIMPPEHFLKRGDSEALAYAFFHIQHWKRIDGALQLLSIVWKDF---VPKVSKDKNAF---SSQLESADKEL 449 Caenorhabditis ...
XP_018668463 402 kyllemKSIILPPEHILKRGDSEAIAYAFYHLPQWKNVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPNCTENADREL 481 vase tunicate
XP_003220504 498 LPT-FHDVSVYPQKELPFFIHFTAGLCSFTAMLALLTHQFPELMVIFTKA---FFGTLLSPLSFMMEKIERLMPAGLWHQ 573
XP_030856337 467 LPSaFHEVSVYPKKELPFFILFTAGLCTFTASLALLTHQFPEPMGAIAKA---FLSSLSAPFSFMMERLEGIIPASLLQQ 543
XP_017946694 487 LPA-FHDVSVYPKKELPFFIHFTAGLSSFTAMLALLTHQFPELMGAFAKT---FLVTLLTPLSFVVEKIESIIPYNFWHQ 562
A7S641       473 LPV-HHQLSVYPKKELPFFILFTAGLCSFTALLALLTHQFPEPMAHLAKT---SLGWISAPFSLLIQKVEDFFPAHILHQ 548 starlet sea ane...
XP_001949568 452 LPT-YHKVSVFPKKDLPFFIHFTAGLSSFSALLALLIYLHPQFTGNLVYI---ICMWIIVPVNYCLDRLETMLPNNVMDI 527
Q19337       450 LPS-WHEQSVFPKTEGTLMMLLQTFICLAICILAVLAQQFPASSGEIFRT---AATIGMQFYENSVYTVSQWAPGNIIPY 525 Caenorhabditis ...
XP_018668463 482 LPS-FHYVSVYPKKEWPFFIVFVGCLCSFTAMLAILTHQYPDIMILFAKAlseFLGMLVAPITFILEKLDSLMPTSIWHV 560 vase tunicate
XP_003220504 574 LSQ 576
XP_030856337 544 LTR 546
XP_017946694 563 LTR 565
A7S641       549 LTR 551 starlet sea anemone
XP_001949568 528 LSN 530
Q19337       526 LAS 528 Caenorhabditis elegans
XP_018668463 561 LTR 563 vase tunicate
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