1GYT,3H8E,3JRU,6OME


Conserved Protein Domain Family
PepB

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COG0260: PepB 
Leucyl aminopeptidase [Amino acid transport and metabolism]
Statistics
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PSSM-Id: 440030
Aligned: 854 rows
Threshold Bit Score: 250.421
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1GYT_A         1 ME------F-S------V---KSgspEKqR-SAC--IV-----V-GVFEP-R---RLspiaEQL-D-KISDG-Y-I--SA 45 
WP_046789491   1 MK------F-D------Y---REn--yTv--TEAp-II-----I-GLpANfR---EMdn-fEEV-D-TLLNG---Lt-AR 43 
NP_764191      1 MQ------F-F------I---NQd--TPtS-IET--IV-----V-GVpDHlN---QLge-iKYH-K-TLIKE-R-L--ET 43 
WP_052590572   1 MQ------F-K------V---SSs-lSK-K-SSAkeLNtaksnIy-IYNS-KtqkDV----HSIvS-KEFSTwQ----KS 50 
WP_013344423   1 MSkllivnAdH------A---DAl-fGE-GgWDA--VV-----V--V--G-Ep------------E-RLEAH-PeI--RQ 41 
WP_127020418   1 MSypvaiaVsS------V---QAa-lND-SqWDA--LI-----I--I--A-S-------------DfTAV-T-E-L--QS 39 
ARU40696       1 MFs----sV-Eh---------SNh----pH-PEA--VVh----F--LFTD-Kd--------APL----SLS----IeaNS 36 
WP_013046353   1 MAd----iF-SnatdfgLmepSS----E-P-DTV--LP-----LyVV-TT-K---SW----QAWy--QAAAD-H-H--QR 47 
WP_001009692   1 MN------F-K------L---NNt--LSnE-INT--LI-----I-GIpEHlN---QLer-iSFN-H-IDITE-S-L--ER 43 
WP_011276276   1 MV------N-F------N---LSn--TVlN-SEV--LI-----I-GLpEHiN---QLgy-iSYN-N-EDITK-Q-I--DT 43 
1GYT_A        46 LLR---R-GELEGKPGQTL--LLHHVPNVL-SERILLIGCGKERELDERQYK---QVIQKTINTLNdtgsMEAVCFL-T- 113
WP_046789491  44 IVE---E-KVLSAEPGVVT--TTGVTiQTD-YRKVIAVGLGDAAGLDQTDIQ---RYLGKLFQYLKdtgtKEGQLLM-G- 111
NP_764191     44 LKQ---Y-HVINSSIGKIS--STLIYiDEK-PKRLLTVGLGNLKILSYQRLL---KVWGQLFQYLKdvhvTDCELLL-D- 111
WP_052590572  51 ALKnsnE-TTYTGKNGPIYlcKLEAKSSDS------HSGLlER-SLy-ASAR---EQIGRLTNSLVadksKEITFNFyTe 118
WP_013344423  42 LVS---HaAHVDARiGREP--LMLLAPGLA-GGRLVLAPTGDlTA-EyEDVRrfaEAAQAGVGIALragaRKPLLVV--- 111
WP_127020418  40 EIN---AaAAIDSRIGKET--VLLLSAKAP-GQRLVLSPTGPlDR-DyDDVRsfyDAAKQGISQAKaagaKSPALYViAp 112
ARU40696      37 AAN---R-PEFKSKPGQIA--QAFPPSGP----REIIVGLGDSSKLKVETVR---KAAIKLAQHIDncqlEVIHFA--En 101
WP_013046353  48 WID---G-QGFTPKPGRVI--TLPGQDG-TlAG--AVAIISD------QPi----WDAATIANALPv-----qTWQI-D- 101
WP_001009692  44 LKH---Q-HIIGSKVGKIY--TTAFDvQDQ-TYRLITVGLGNLKARSYQDML---KIWGHLFQYIKsehiEDTYLLM-D- 111
WP_011276276  44 YRH---H-HLISSQLGKIS--STLLPlKDS-SKRLITVGLGNLKTLDYGALL---KAFGNLFQFLKeervTEADVLF-D- 111
1GYT_A       114 ELhvkgrnN---YW-KVrQAVETAKETLYSF-DQLKTNKSEP--RrPlrKMVFN-VPT-RreltsgerAIQHGLAIAAGI 184
WP_046789491 112 TFpy---dQ---EK-LAeALGLMSVISIYEF-ESYKTDRGPLf---Sd-EAALL-ITG-Srdv---rePVSRGVRLGESI 174
NP_764191    112 TFkskhgnI---VE-ICqTLGLQSAQSIFEF-DHYKSDKKPPy---Qg-RVYIQ-TT--Ehni---etKINEGQQLGESI 176
WP_052590572 119 --------S---EE-EIiGSIVGIELALYRF-NG--S---E-----NigTLKFns-fN-Kkvs---tsLVNKAKAIALGV 170
WP_013344423 112 -Aeh---dDlrySN-ALeVALLGAGHEIYQPfDV----AG------PdvTLGVLgLd-----------DMARANALENGR 165
WP_127020418 113 -------dPdayQY-AAeVAYLGACQALWQPlEG-REARGEAviE-PvtQIGVIgVTe---------yQARYMDAVEAGK 173
ARU40696     102 SIl----nE---IQ-FGqAIGIGFQLASYNP-RQMPGSRTEP--E-P--EVSLQ-IKAlSeqf---dkGLARGIGLGSAV 163
WP_013046353 102 HHa----lG---TSfDd-SFLLGWALAHYRY-TTYRDKPAPA----Ra-SI--M-VPae--------sdSTRIMGLASGT 156
WP_001009692 112 SFiskydqL---SD-VLmACGIQSERATYEF-DHYKSSKKAPf---Kt-NLNLI-SE--Slie---ldFIHEGISIGQSI 176
WP_011276276 112 TLiskkieQ---TK-VAeVMGLQSEQAVYSF-DNYKSDKFAPy---Ql-ELNIS-TN--Kedl---qrYFINGAIIGQSV 176
1GYT_A       185 KAAKDLGNMPPNICNAAYLASQARQLAD-S-YskN-VITRVIGEQQMKELGMHSYLAVGQGS----QNESLMSVIEYK-G 256
WP_046789491 175 AMARNFSETPPNIMTPEHMADKVAAIFK-D-R--KyISGRVKDDETLEEEGYGLITAVGKAS----KAKPRLVTIEYKhP 246
NP_764191    177 NYARELSQMPPNILTPQYFAEEIKKHFE-G-S--S-VSVDIKDHRQIIDEGFGLIHAVGKGS----NHGPRLITVSYY-G 246
WP_052590572 171 NQARHLVNLPPNDLNPVSYANEVKDLFKtS-K--T-MKVTILDEKKLQKENCNLLLSVGMSS----NNKPRIVHLKYR-P 241
WP_013344423 166 IAARDLCGGDPEQMAPPAFADYCVELFA-D-S--P-VSVSVIDDPETLVRDYPLLSAVARASfavpRHAPRVVRLEYV-G 239
WP_127020418 174 RVARDLCGTEPERMAPRRFADYCVETFA-G-T--D-VQVSVETKVDTLQKDYPLLMAVARSSlqveRHKPAVIRLEYQ-G 247
ARU40696     164 NFTRRLVNTPPNIANPLWIADQALELSS-RcP--G-LSVRVIQGQELEEEWLIGHINVGRAS----SNPPCMTRIEWN-P 234
WP_013046353 157 YLGRDMINMPPNKMNPAGLEDTARALAK-T-H--K-AKITVIAGAKLAS-DFPAIDCVGRAA----ECPPRLIDMRW--- 223
WP_001009692 177 NLARDFSNMPPNVLTPQTFAEDIVNHFK-N-T--K-VKVDVKDYDTLVSEGFGLLQAVGKGS----KHKPRLVTITYN-G 246
WP_011276276 177 NVARDYSNMPPNILTPNYFAEQVTQHFD-Q-T--S-VKVDIKDGKQLLDEGFGLIHAVGKGS----ENPPVVITMTYN-G 246
1GYT_A       257 nA-SEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAE-LQLP-INVIGVLAGCENMPGGRAYR 333
WP_046789491 247 -S-AESCRPVALVGKGVTYDTGGYSIKSKTGMPGMKYDMSGAANVIGMMHAVSE-LELP-VHVVGVIALAENMVDGNGMR 322
NP_764191    247 -A-EADEPPISLVGKGITYDSGGYSIKSKIGMQTMKYDMCGAANVIGMIDVISK-QNLP-VNIVGIIASAENMIGESSMK 322
WP_052590572 242 -K-GASKKSVALIGKGITFDSGGLDMKPAAGMRYMKKDMGGSACLVGFSRWLES-SGVR-KNVDIYLALAENAVSENASR 317
WP_013344423 240 -E-GVISRNWFLAGKGVTFDTGGADLKIGGAMAGMSRDKGGAAAVAGLMATLAQ-LQPKgVRVVAELGLVRNSIGSEAFV 316
WP_127020418 248 -E-GDIEQTLLFAGKGLVYDTGGADLKIGGGMAGMSRDKGGAAAVAGFIKTVAL-LKTKgIRIIAEIGAVRNSIGSDAFV 324
ARU40696     235 -NpSANQKPIVLVGKTITYDTGGLSIKSKTGMPGMKHDKAGGCAVLGVMQAVSEvIK-PnFPVVALLTAAENSIDATAYR 312
WP_013046353 224 -G--KSGPKITLIGKGITFDSGGLDLKPSKAMEMMKKDMGGSAIALGLANALMH-ANVP-IKLRVLVPTAENAVSERSMR 298
WP_001009692 247 -K-DKDVAPIALVGKGITYDSGGYSIKTKNGMATMKFDMCGAANVVGIIEAASR-LQLP-VNIVGVLACAENMINEASMK 322
WP_011276276 247 -G-DSEDAPIALVGKGITYDSGGYSIKSKIGMQTMKFDMCGAANVVGMIDAISR-LQLP-INIVGVIASAENMISSNAMK 322
1GYT_A       334 PGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYV-ER---F-EPEAVIDVATLTGACVIALGHHITGLMAN---HNP-LAH 404
WP_046789491 323 PDDVYTSYSGQTVEVKNTDAEGRLVLGDAVFHAsQ----Y-SPSLIMDFATLTGAVVAALGTKRSGIFTN---KKPgFLT 394
NP_764191    323 PDDVFTALNGETVEMLNSDAEGRMVLGDAVFYAtQ----F-KPQLILDFATLTGAAIVALGDDKAVAFQSh--AEN-ELK 394
WP_052590572 318 PSDIYKARNGLTVEIHNTDAEGRLALADAMDLAlE----L-KPEVMIDVATLTGAGKVALGQDIASLFSN---NDA-LAD 388
WP_013344423 317 PDEIIESHAGVKVRIGNTDAEGRLVLADVLSHLrLAaaeSdDP-VMMSLATLTGHVGRAYGPYSAVIENGvarGQA-MGG 394
WP_127020418 325 PDEIITSHAGVRVRIGNTDAEGRLVLADLLSHLrEDaktAvNP-TLYSIATLTGHAARAVGPYSALVENGaarRMG-LSA 402
ARU40696     313 PDDVITYRNGVTVEVTNTDAEGRLVLADGLCWAcEI---E-NPVCVVDIATLTGGVVTALGAEFAGLFTE---NQH-LLT 384
WP_013046353 299 PLDIIDTRAKLKVEIGNTDAEGRLVLADAITYAlE----D-EPDLMIDFATLTGAARVALGTELPALFAN---DDN-VAR 369
WP_001009692 323 PDDVFTALSGETVEVMNTDAEGRLVLADAVYYAnQ----Y-QPSVIMDFATLTGAAIVALGDDKAAAFESn--SKV-ILN 394
WP_011276276 323 PDDVLTALNGETVEMLNSDAEGRLVLGDAVFYAnQ----F-QPKIILDFATLTGAAVAALGEDKAALFNSn--ADK-EIE 394
1GYT_A       405 ELIAASEQSGDRAW-RLPLGDEYQEQ-LE-SNFADMANI-G-GRP---G-GAITAGCFLSRFTR--K--------YNWAH 465
WP_046789491 395 PFFDISRETGEEIW-QLPITEIEEKN-VKsSNIADLTNH-V-EKP---G-RASFAACFIKQFAN--G--------TPWVH 456
NP_764191    395 NLLTVARHVDEKVF-ELPITETERHL-IKqSDVADLVNH-T-NGQ---G-KALFAAAFISHFSG--D--------IPHIH 456
WP_052590572 389 ELLSSSHKMGDLVW-RMPLYNPYFSG-LK-SDFADMVNS-A-SGH---G-GAITAALFLQKFVG--K--------TKWAH 449
WP_013344423 395 QLQMVSELWGEPFElSRLRREDYAQvaaR-SPSERLLSS-NnGASvniArGHQFPMAFLVQASGldQhglgsdhpIAYMH 472
WP_127020418 403 DLAMVGDLWADPSEiSRSRREDFSFikgR-SSADDLLSC-NnAPSsvtPrGHQFPMAFLVAAAGldQhalnteqpLPYCH 480
ARU40696     385 EIKTAGELSGEEVW-QLPLTDGFRDM-MK-GSVSDIVNSvP-GGK---G-HASQGAAFLSCFVTp-D--------VPFAH 447
WP_013046353 370 AIIDASNKAHDPLW-QLPLFDDYDRH-LD-AGYAAMSST-GaSGY---G-GAITAALFLRRFAG--Td-------SNWAH 432
WP_001009692 395 DILQISSKVDEMVF-ELPITATERAS-INhSDIADLVNH-T-NGQ---G-KALFAASFVTHFSG--Q--------TPHIH 456
WP_011276276 395 EIRVSAKEMDEYAF-ELPMTQTEQRL-IRqSDVADLVNH-T-NGH---G-KALFAATLITHFSG--S--------TPHIH 456
1GYT_A       466 LDIAGTAWRSGK-----AKGATGRPVALLAQ-FLLN---R 496
WP_046789491 457 FDIAGTGTASKRtp-ygPAGATGVMIHTVVK-YLETgdvH 494
NP_764191    457 FDIAGPATTKSAty-kgPKGPTGYMIPTVVE-WLQQ---K 491
WP_052590572 450 LDIFA--WTNGSkpslvQKGGSGQGVETLIG-YFs----- 481
WP_013344423 473 LDIAASAVEKRDpl---ygQPTAAPVATLLA-NLLD---H 505
WP_127020418 481 IDIAGSGVDGGDwq---hgKPSASPVAALAAhYC-----L 512
ARU40696     448 IDMAGLSHTRGDef--pVDGPSGWGVRLLAQ-FLTA---R 481
WP_013046353 433 IDVMA--WNLSArp-grPKGGEVMSLRALFD-YIDG---L 465
WP_001009692 457 FDIAGPATTNKAsy-ngPKGPTGFMIPTIVQ-WLKQ---Q 491
WP_011276276 457 FDIAGPATTNKTsy-kgPKGPTGSMITTVLN-WLR----- 489
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