1WEE


Conserved Protein Domain Family
PHD_MMD1_like
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cd15556: PHD_MMD1_like 
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PHD finger found in Arabidopsis thaliana PHD finger protein MALE MEIOCYTE DEATH 1 (MMD1), PHD finger protein MALE STERILITY 1 (MS1), and similar proteins
MMD1 is a plant homeodomain (PHD) finger protein expressed in male meiocytes. It is encoded by the gene DUET, which is required for male meiotic chromosome organization and progression. MMD1 has been implicated in the regulation of gene expression during meiosis. The mmd1 mutation triggers cell death in male meiocytes. MS1 is a nuclear transcriptional activator that is important for tapetal development and pollen wall biosynthesis. It contains a Leu zipper-like domain and a PHD finger motif, both of which are essential for its function.
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Statistics
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PSSM-Id: 277031
Aligned: 10 rows
Threshold Bit Score: 77.4198
Created: 12-Aug-2013
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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Zn binding siteputative
Conserved site includes 8 residues -Click on image for an interactive view with Cn3D
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C C H C C CClick to see conserved feature residue pattern help
Evidence:
  • Structure:1WEE; Arabidopsis thaliana At1g33420 binds two Zn2+ ions through its PHD finger.
  • Comment:The PHD zinc finger is characterized as Cys4HisCys3.
  • Citation:PMID 7583761
  • Citation:PMID 7701562
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1          #  #                #  #    #  #                #  #
1WEE_A         18 DCk-CGTk----dDDGERMLACDgCGVWHHTRCIGInnad--alpsKFLCFRC 63   thale cress
XP_003079461  927 QCm-CGTg----dDDGERMIACDkCGVWMHTRCVGIkdnk--napsHWICPNC 972  Ostreococcus tauri
XP_001780078  607 DCp-CGTk----dDDGERMIACDvCEVWQHTRCGGIsdmd--vipqRFLCHRC 652  Physcomitrella patens subsp. patens
XP_001695692 1902 ACl-CGTq----dDDGERMIACDvCGVWSHTRCNDIadel--deppAFVCREC 1947 Chlamydomonas reinhardtii
EIE21728      877 ACs-CGTr----dDDGERMIACDgCCEWSHTRCAGFadal--pspdHFLCPRC 922  Coccomyxa sp. C-169
ETV66193      544 SCs-CGIvav-nyDDGCRMIACDrCNTWQHTLCAGIpnet--eppdVYLCRSC 592  Aphanomyces astaci
EEY60006      169 DCv-CDIrrqlnhDDGQRMVECEsCETWQHTKCVGIpmte--epadDYRCPRC 218  Phytophthora infestans T30-4
EQL35725      449 DCsgCGVhge-nlDDGSHIVACEkCNVWQHIKCLGIaqdeaekddfHFVCRDC 500  Ajellomyces dermatitidis ATCC 26199
Q9FMS5        616 ECe-CGAt----eEDGERMVCCDiCEVWQHTRCVGVqhne--evprIFLCQSC 661  thale cress
Q7X6Y7        608 KCi-CRAr----dDDGERMISCDvCEVWQHTRCCGIddsd--tlppLFVCSNC 653  thale cress

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