Conserved Protein Domain Family
Whi5

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pfam08528: Whi5 
Whi5 like
In metazoans, cyclin-dependent kinase(CDK) dependent phosphorylation of the retinoblastoma Tudor suppressor protein (Rb) alleviates repression of E2F and thereby activates G1/S transcription. The cell size regulator Whi5 appears to be an analogous target of CDK activity during G1 phase.
Statistics
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PSSM-Id: 462511
Aligned: 69 rows
Threshold Bit Score: 37.715
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EOA86221     158 QLKTRLSYAMVKVQNGWEKQSLDEL 182
ESA43272     194 ILRLRLSLAAYKIQTGQTDVPLEQL 218
EHA53965     163 TLRLRLRLAAYKLKTGQADVPLEQL 187
CDP32564     171 ILRLRLGLANYKVRTGQEDVSLDQL 195
Q2H6R4       197 iIRLRLGLASYKVRTGQTDVPLDRL 221 Chaetomium globosum CBS 148.51
CCE31714     147 ILRLRLGLASYKLRTGQTNVPLADL 171
EFX00111     173 ILKLRLGLASYKLRTGQVSVPLDQL 197
EPE36158     202 KMRLRLQLAAYKVQTNQIDVPMSRL 226
EKD11902     204 eIKLRLRLASYKVRTNQIDIPISRL 228
XP_007778790 213 TLRLRLRIAMYKVRTNQTAVPLSRL 237
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