5O2U


Conserved Protein Domain Family
Gag_p6

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pfam08705: Gag_p6 
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Gag protein p6
HIV protein p6 contains two late-budding domains (L domains) which are short sequence motifs essential for viral particle release. p6 interacts with the endosomal sorting complex and represents a docking site for several cellular and binding factors. The PTAP motif interacts with the cellular budding factor TSG101. This domain is also found in some chimpanzee immunodeficiency virus (SIV-cpz) proteins.
Statistics
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PSSM-Id: 312289
Aligned: 131 rows
Threshold Bit Score: 31.8116
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5O2U_A 449 LQSRPEPTAPPEESFRFGEEtTTPSQK---QEPIDK-El-----yPL 486
Q5U6U1 448 PQSRLEPTAPPAEILGMRDE-ICPPLRgrsRRTRSRpH-------PL 486 Human immunodeficiency virus 1
Q87621 477 KEEVVEPTAPPIEIYQ--EE----------HKRTQKgLkgeeelpPS 511 Simian immunodeficiency virus
Q66Q77 450 LQKQVAPSAPPMEEGMQGQE----------NQEQ-Kegpt--elyPF 483 Human immunodeficiency virus 1
Q6Y939 454 VQKQVPPSAPPMEEVMQGQK----------NQNQ-ExRedpnelyPF 489 Human immunodeficiency virus 1
Q6Y903 454 MQKQVPPSAPPMEEMMKGQE----------NQEQ-Kgdtt--elyPF 487 Human immunodeficiency virus 1
Q6Y8S3 454 VQKQVHPSAPPMEEETKGQE----------SQEQ-Kgspn--elyPF 487 Human immunodeficiency virus 1
Q6Y8Z4 454 AQRQVSPTAPPMEEEVKRQE----------NQEQ-Kgdqn--elyPF 487 Human immunodeficiency virus 1
Q6Y8U9 454 VQRQVPPSAPPMEEVVKGQE----------NQNQ-NqGgdqnelyPF 489 Human immunodeficiency virus 1
Q6Y912 449 LQKQVSPSAPPMEEVVKEQE----------DQNQ-Gkdqn--elyPF 482 Human immunodeficiency virus 1
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