Conserved Protein Domain Family
RMI1_N

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pfam08585: RMI1_N 
RecQ mediated genome instability protein
RMI1_N is an N-terminal family of eukaryotic proteins. The domain probably carries an oligo-nucleotide-binding domain or OB-fold, and forms a stable complex with Bloom syndrome protein BLM and DNA topoisomerase 3-alpha.
Statistics
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PSSM-Id: 462527
Aligned: 99 rows
Threshold Bit Score: 125.075
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:MYCTH_116885  11 LSTTSIPVPSLAWLEALAGARSpap-------plaSLLATARARLLASDLTAPgll--darYAAAhsLPARLAQthagtr 81  
OWR54467          14 LKNS-HINVKHDWLQGCIEYLHekgy------dpnSISKITKEQWLLNDLKEV--------S--LgcLPSNLKKqtl--- 73  
PDM80685          14 FLEN-HILLRDDWVKAVLNFALqkfpt----ysgrRLYNLLFEQWLYSNLSES--------C--YptLEGIDAQart--- 75  
CAP36665          12 FGDR-HILLKEEWLNSVIDFLHnhvpls-rdfdneTFANIVLDQWTCSNIESTsfpafgnhG-----IDSSIQKq----- 79  
XP_003104405      12 FNER-HILLKDEWLNSVIEFLHqklpss-rgfsdeKFANLVLDQWTCSHIENTsfpvfgnhG-----IDANVAKq----- 79  
CDP90636          10 FSEKLNVTLHEEWLTEVMKYLYslgf------ssnSLLSSVYEQWLYTNLKIS--------TKPLlsLSADNCSkr---- 71  
CAP23335          10 FAKK-HMQLKAAWLKTCIEFLKrtvnse--iqssdAICDQVMLQFLYSNLSDS--------LVPVmkIPDHaak------ 72  
XP_003111476      13 LAQK-HLPLKLEWLKICIKYLEksvdan--mrrslKMFDLVMQQFLNSKISDT--------LNPVmkIPINask------ 75  
EGT38899          13 FKRK-HIPLKSEWLKICIEYLEqnlgkk--lplseETLNLVIQQFLHSNLSES--------LNPVlkIPTNavk------ 75  
P91399            13 LARK-HYPFKREWLRICVQYIEgslgqriktvdvkQIGELVIQQFLNSKISEA--------LDPTmkIPTSavk------ 77   Caenorhabd...
jgi:MYCTH_116885  82 eaaLPHDVVV--------------QVLDVEDVARSRWEQVEALEAlergegtrgreiirlntassssssssgadgtaega 147 
OWR54467          74 -viLDGNFVL--------------QVNSEIDLSTSVYQQYSKLKN----------------------------------- 103 
PDM80685          76 -idVHQPLVL--------------QITSLIDIGTSLLSQFNKLTYe---------------------------------- 106 
CAP36665          80 --hLQGPIVC--------------QVNGFIDTGSPYYQQYCNLNRsg--------------------------------- 110 
XP_003104405      80 --rLQGPIVC--------------QINGFIDTGSPYYQQYCNLSGrng-------------------------------- 111 
CDP90636          72 -mmLGGNTVV--------------QVNSVVDIGTSMYSQYRNLTNk---------------------------------- 102 
CAP23335          73 vilVKKMVF---------------QVVTYVNISVSLFEQLSECTRhnddlsw---------------------------- 109 
XP_003111476      76 vmiVKRMVF---------------QITSYTNISVSLYEQLSVCTRhnedlsw---------------------------- 112 
EGT38899          76 viiVKRMIFEvpfitflnpqmlvvQMTSCTNVSTSLYEQLSECTRhnedlsw---------------------------- 127 
P91399            78 vviVKRMIF---------------QVISSTNISTSLYEQLSECTRhnedlaw---------------------------- 114  Caenorhabd...
jgi:MYCTH_116885 148 eeeeeeeggnaaagAGGGGggggrggAtstsnnnnnnnssssSSSSKNGTHKLVVQDCkGQKVHAIELKRVERLGVgRTF 227 
OWR54467         104 --------------VNNENieatiktE---------------EKITSNRLLKFFLTDG-VQDVTAIEYKCINKIKN-DLN 152 
PDM80685         107 -------------fMDNSGfdidpndQked----------nlYQPKPSRCLMLTLSDG-EKELKGMERRHIPSLSL-LTT 161 
CAP36665         111 ------------kkEDNSGfekvfheKed------------dSDQKPSRLLKLSLTDG-ESFLNAIEFWKCPQLSL-HCK 164 
XP_003104405     112 ------------kkEDNSGfervfheKed------------dSDQKPSRLLKLSLTDG-ESSLHAIEFWKCPQLSL-HLK 165 
CDP90636         103 -------------fEDNSGfqlkmeeNetn----------tdPFQNAKRMLSMEVTDG-QLSMKAVEYSMLSALSL-LTC 157 
CAP23335         110 -------fhggaelHDDRNlekdhtc---------dknnnmrVIPKKRGMLKLEITDG-QNKLEAVELEDVFDESL--LV 170 
XP_003111476     113 -------fhggsnmHHDEEnretekdTifqaad---knnnfrPIPKKRGMFKLEITDG-LNTVKAIELEEIFDETL--VV 179 
EGT38899         128 -------fhggskmIPDESnrekeedTtfnnqvd-dnnnkkrTIYKKRGMLKLELNDG-VNSVKAIEIEEVFEEEH--LV 196 
P91399           115 -------fhggskaDHEEEnrdkekdVasdrmn----htqtkNAIKKRGMLKIELTDG-VNTLKAIELDEVFDEKI--ML 180  Caenorhabd...
jgi:MYCTH_116885 228 IGEKILLRAGTVLARGVVLLDPAHCVVLGGKVESWHRAWLDGR 270 
OWR54467         153 SGYKILVKGPIVCRNGVIFLTDKDVEMMWGEVKEFSITNSKIS 195 
PDM80685         162 PGCKVVLRPPLVCRKGVFLLTPQNVQVLGGDEPNLMETGRPLN 204 
CAP36665         165 PGTKLLIEPPCDIRRGTFLLKPGNCRILGGEVLPLLNCHLPVE 207 
XP_003104405     166 PGTKLLIEPPCDIRKGNFLLKPNNFKILGGEVLPLLNSYLPVE 208 
CDP90636         158 PGCKILLTNNVCIRRGILLLTELNCIVLGGDDESLMKTGRPVE 200 
CAP23335         171 PGVKILLTGSVKCRRGILLLEKSNCDLLGGRVDSLKIDKVTQL 213 
XP_003111476     180 PGSKILLTGSVKCRRGVFLLEKSNCMFLGGQIESLHIDKIKQL 222 
EGT38899         197 PGVKILLTGRVKCRRGTLFLEKSNCSLIGGRIEALKFDKVKQL 239 
P91399           181 PGAKIILTGKVKCRRGNLLLDKSNCAFLGGRVESLSFDKVAQL 223  Caenorhabditis elegans
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