Conserved Protein Domain Family
NrdD

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COG1328: NrdD 
Anaerobic ribonucleoside-triphosphate reductase [Nucleotide transport and metabolism]
Anaerobic ribonucleoside-triphosphate reductase is part of the Pathway/BioSystem: Thymidylate biosynthesis
Statistics
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PSSM-Id: 440939
Aligned: 294 rows
Threshold Bit Score: 422.789
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015732220   1 MIFTVKKRDGREMPFNIEKIADAVIKAFRASGEldeqikasqaqmnllgsddlLTNVALKVAAEAVGHLEAenkTKPDIE 80 
WP_012802661   1 --MKVIKRNGSEVIFDVTKIVNAIAKANEEVVPen----------------rlSQAQILTAANNVTTECEAc-gHAPAVE 61 
WP_013252350   1 --MKIIKRNGSEVQFDLEKIVNAINAANAEVTAde----------------rlTEREVRFAALNVEDACKAa-gHTVTVE 61 
WP_013282300   1 --MKIIKRSGKEVDFDVSKISAAIEKANKEVTEek----------------rlTHGQIIDIATGVEKLCATl-tRAASVE 61 
WP_013498514   1 --MKIIKRNGAEEVFDPDKIINAVKKANIA-GEkg----------------riSDEEIADVTDYVEYKCNKl-gRAVTVE 60 
WP_041738569   1 --MKIIKRSGVEVAFDVDKISSAIRGANKEVKEad----------------rlTERQVIYASQNVAEACERa-gHTVSVE 61 
WP_014116946   1 --MKIIKRNGSEEVFDRAKIAAAVEKANRACDQtp----------------elSQAQTDQIALNVETAAEKv-gRTLSVE 61 
WP_009204371   5 VKTKIIKRNGEEVTFDLDKIINAITKANEEVTKih----------------qmNQYQIMAIAEKVADQVANs-sHAVNVE 67 
WP_005934848   1 --MKIIKRNGSEVPFDITKIITAVTKASDSVSRks----------------slTQEQILSIANDVTEQCQAl-nRAVSVE 61 
WP_106056481   1 --MNVIKRNGSEVTFDKAKIENAIIKANNSVEEav----------------rlTPIQIKRITDSVILSCEDl-gRSPAVE 61 
WP_015732220  81 EIQDAVEKALTEGGYAdtaksyiLYRAERTRVrevntRLMQTLHDITFSsakeSDLKRENANIdGDTAMGTMLKYGSESA 160
WP_012802661  62 EIQDMVEDQIMALGCFevarkyiIYRYLQNQKrasntTDDKILSLIECNn---EEVKQENSNKnPAVVSVQRDYMAGEVS 138
WP_013252350  62 EIQDLVEDQIMALDRFavarkyiIYRYLQNQKrhkntTDDKILSLIESNn---EEVKQENSNKnPTVVSVQRDYMAGEVS 138
WP_013282300  62 EIQDMVEDGLMRAGKFdvarkyiTYRYKHALVrksntTDEQIMSLIECSn---EEVKQENSNKnPTVNSVQRDYMAGEVS 138
WP_013498514  61 EIQDMVENQLMAKGAFelarryvRYRYTRSLVrksntTDNKILSLIECAn---EEVKQENSNKnPAVNSVQRDYMAGEVS 137
WP_041738569  62 EIQDLVEDEIMALDRFevarryiIYRYLQGLKrqkntTDDKILSLIEHNn---EEVKQENSNKnPTVNSVQRDYMAGEVS 138
WP_014116946  62 EIQELVETELMRHSAYetakryiRYRYTRTLAraantTDNQILSLIECNn---EEVMQENSNKnPTVNSVQRDYMAGEVS 138
WP_009204371  68 DIQNMVETGIMEMRGYevaqkyvRYRFKRELRrksntTDDGILSLLDNIn---EEVNQENSNKnPVINSTQRDYMAGEVS 144
WP_005934848  62 EIQDMVENKLMDIQAHdvarhyiTYRYVQSLKrqtntTDERILSLIECQn---EEVKQENANKnPTVNSVQRDYMAGEIS 138
WP_106056481  62 EIQDMVEEHIMQHGAYevakayiTYRYTRSLVrqsntTDDKILSLIELNn---EEAKQENSNKnPIINSTQRDYMAGEVS 138
WP_015732220 161 KHFYTMmMLKPEHSRAHMDGDIHIHDLDFYsLt-MTCCQIDLIKLFKNGFntgHGHLREPKDIRSYAALAAIAIQSNQND 239
WP_012802661 139 KDLASRmLLPQDVVWAHENGLIHFHDSDYYaQrmHNCDLVNLEDMLQNGTvisGTLIEKPHSFSTACNIATQIIAQVASC 218
WP_013252350 139 KDLAMReLLPADVVEAHKAGIIHFHDADYYaQhmHNCDLVNLEDMLQNGTvisGTMIEKPHSFSTACNIATQIIAQVAST 218
WP_013282300 139 KDITRRfLLPEDVVKAHEEGLIHFHDSDYFaQhmHNCCLVNLEDMLQNGTvisETMIERPKSFSTACNIATQAIAQIASS 218
WP_013498514 138 RDLTKRlLLPPDIVEAHEAGIIHFHDTDYYaQhmHNCDLVNLEDMLQNGTvisETLIEKPHSFSTACNIATQIIAQVASN 217
WP_041738569 139 KDLTARvLLPRDIVKAHNEGIIHFHDSDYFaQhmHNCDLVNLDDMLQNGTvisGTLIEKPHGFSTACNIATQIIAQVASN 218
WP_014116946 139 KDITKRlLLPPDIVEAHQEGIIHFHDMDYYaQhmHNCDLVNLEDMLQNGTvisGTLIEKPHSFSTACNIATQIIAQVASS 218
WP_009204371 145 KDLSKRvLLPNEIIRAHEEGIIHFHDSDYFaQreHNCDLINLEDMLQNGTvisETLIEKPHSFFTACNVTTQIVAQVASN 224
WP_005934848 139 KDLTARlLLDPEIVKAHNEGLIHFHDSDYFaQhmHNCDLVNLEDMLQNGTvisGTYIEKPHSFSTACNIATQIIAQVASN 218
WP_106056481 139 KDLTRRiLLPEEISAAHDAGIIHFHDSDYFaQkeHNCDLIDLEDMLQNGTvisETLIEKPHSFYTACNITTQIIAQVASN 218
WP_015732220 240 QHGGQSVPnfDYAMANGVrityrkaylsnmvkalmlltgkteeeiqpvvkklhsemaemgmvatlvpnekfqtteahels 319
WP_012802661 219 QYGGQSIS--LAHLAPFVdisrqkirraviaeln---------------------------------------------- 250
WP_013252350 219 QYGGQSIS--LAHLAPFVdvsrkkirrqvyaeme---------------------------------------------- 250
WP_013282300 219 QYGGQSIT--LSHLVPFVdvsrqkfrkevalefe---------------------------------------------- 250
WP_013498514 218 QYGGQSIS--LAHLAPFVqisrvkirkelevema---------------------------------------------- 249
WP_041738569 219 QYGGQSIS--LTHLAPFVevsrrkirreverela---------------------------------------------- 250
WP_014116946 219 QYGGQSIS--LAHLAPFVqvsreklrsdvlaeaa---------------------------------------------- 250
WP_009204371 225 QYGGQSFT--LAHLAPFVdisrkklrknvvkerk---------------------------------------------- 256
WP_005934848 219 QYGGQSIS--LTHLAPFVdvsrkkiaaeveaem----------------------------------------------- 249
WP_106056481 219 QYGGQSFS--LAHLAPFVdvsrqkirtkvekefk---------------------------------------------- 250
WP_015732220 320 ktydaetvknaqkfaekmaYEETDKATFQAMEAFVHNLNSMHSRAGaQTPFSSINYGMCT------EPEARMVMKNLLLT 393
WP_012802661 251 ----dlgleatgdrldtvvEARVRDEIRRGVQTIQYQVVTLMTTNG-QAPFITVFMYLNEarneqeKHDLAMCIEEMLRQ 325
WP_013252350 251 ----aigarpgadkigqlvEKRLREEVARGVQTIQYQVVTLMTTNG-QAPFITVFMYLNEakdeqeKSDLALCIEEMLRQ 325
WP_013282300 251 ----tagvkvnkkqvdeiaEMRVRKEIERGCQVIQYQVITLMTTNG-QAPFITVFMYLDEvpegqqREDLALVIEEMLKQ 325
WP_013498514 250 ----klgvtptqekldmitEERLRKEITRGVQTIQYQVVTLLTTNG-QAPFVTVFMYLNEakndqeKKDLAMIIEETLKQ 324
WP_041738569 251 ----elgahadeddiskvvEDRLRDEIRRGVQTIQYQVVTLMTTNG-QAPFVTVFMYLNEarsadeKRDLAMIIEETLRQ 325
WP_014116946 251 ----amgghpdedtlnrivEKRLRSEIRRGVQTIQYQVVTLLTTNG-QAPFVTVFMYLGEvsdpqsKHDLAVIIEETLNQ 325
WP_009204371 257 ----vigesmddaiidkitEMRLYDEIKQGIQTIQYQLVTLMTCNG-QAPFVTVFMYLDEvpegqtRDDLALVIEEVLKQ 331
WP_005934848 250 -----egldvtperkkeivERRLRNEINRGVQTIQYQVVTLMTTNG-QAPFITVFMYLGEarnaqeKADLAIIIEETIRQ 323
WP_106056481 251 ----dagiettqealnkvvEDRLRDEIKSGIQTIQYQLITLMTCNG-QAPFVTMFMHLEEapegrtRDDLALCIEEVLKQ 325
WP_015732220 394 TEEGLG-GGE---TAIFPIQIFRVKDGiNLNPGEPNYDLFKLACRVSAKRLFPNFSFQDApynlqyYkp-----gHpETE 464
WP_012802661 326 RHQGVKnEAGvwiTPAFPKLIYVLEDD-NIEADSPYYYLTQMAAKCTARRLVPDYISEKKmk--eyKlsageeagN-GDC 401
WP_013252350 326 RYQGVKnEEGvwiTPAFPKLIYVLEDD-NVHEGDPYFYLTRLAAKCTAKRMVPDYISEKKmr--eyKlstgevegE-GDV 401
WP_013282300 326 RILGVKnEKGqliTPAFPKLIYVLDED-NIHEDSKYWYLTELAAKCTAKRLVPDYISAKKmk--elK--------K-GDV 393
WP_013498514 325 RTEGVKnESGvwvTPAFPKLIYVLEED-NVEEGTPYFYLTKLAAKCTAKRMVPDYISEKVml--klKvdk---ngD-GHC 397
WP_041738569 326 RYEGVKnEAGvwiTPAFPKLIYVLEED-NVEEGAPFFYLTQMAAKCTAKRMVPDYISEKKmr--elKlsageqpgE-GDC 401
WP_014116946 326 RYQGVKnEAGvwiTPAFPKLIYVLEED-NVRPGTPYYYLTELAAKCTAKRMVPDYISEKIml--esKidk---ngE-GHC 398
WP_009204371 332 RIQGVKnEKGvwiTPAFPKLIYALDDD-NITPDSKYWHLTELAAKCTAKRMVPDYISAKVmr--elK--------N-GEV 399
WP_005934848 324 RYQGVKnEAGvwiTPAFPKLIYVLEED-NIRPGTPYYYLTELAAKCTAKRMVPDYISEKKml--elKvdk---ngE-GHC 396
WP_106056481 326 RMQGVKnEKGvwiTPAFPKLIYVLDDC-NIREDAPYWHLTEIAAECTSKRLVPDYISAKVmr--elK--------K-GNV 393
WP_015732220 465 ISYMGCRTRVIGNhyd------------------psrEISYGRGNLSFTSINLPRIAIKMK-SVDLFFKELDRMLQLVSD 525
WP_012802661 402 YTCMGCRSFLTPDrsgngynnva-----nvanwdptkPKYYGRFNQGVVTINLVDVALSSEgDINKFWEVFDERLELCHK 476
WP_013252350 402 YTCMGCRSFLTPDrseggygnva-----nagnyvpgkPKYYGRFNQGVVTINLPDVALSSGqDADRFWQILDERLELCHK 476
WP_013282300 394 YPCMGCRSFLTPDseenaeglcnkgnksharnyeegdHKYYGRFNQGVVTINLVDVACSSFkDEEKFWAILEERTELCKR 473
WP_013498514 398 YTCMGCRSFLTPYide------------------ngkPKYYGRFNQGVVTINLVDVALSSGrNKDTFWKIFDERLALCYK 459
WP_041738569 402 YTCMGCRSFLTPDrsgdgygnva-----rarnhvpgaPKYYGRFNQGVVTINLPDVALSSGkDEDEFWRIFDERLELCHR 476
WP_014116946 399 YTCMGCRSFLTPYvdpe-----------------tgkPKYYGRFNQGVVTINLVDVALSSGgDYDRFWEIFSERLELCYR 461
WP_009204371 400 YPCMGCRSFLTVEdsqrn---------------adgsHKFYGRFNQGVVTINLVDVACSSNgDMDKFWDILEERLELCHR 464
WP_005934848 397 YTCMGCRSFLTPYvdpe-----------------tgkPKYYGRFNQGVVTINLVDVALSSGgNFEKFWKIFDERLALCHK 459
WP_106056481 394 YTCMGCRSFLTVEesqkn---------------adgsYKFYGRFNQGVVTINLVDVACSSYgNMDKFWEILDERLELCHR 458
WP_015732220 526 QLMERFAV-QSrRKVKNFPFLMGQgvwidsdkLGWEDTVGEVIKHGTLS--IGFIGLAETLVMLTGKHHGeSEASQELGL 602
WP_012802661 477 ALLCRHNRlKG-TLSDAAPILWQYgal---arLEKGETIDKLLYGGYSTisLGYAGLYECTKYMTGKSHT-NPEATPFAL 551
WP_013252350 477 ALRYRHDRlCG-TLSDAAPILWQYgal---arLRKGETIDRLLYGGYSTisLGYAGLYECVKYMTGKSHT-DEEAKPFAL 551
WP_013282300 474 ALMCRHERlLG-TPSDVAPILWQNgal---arLQKGEVIDPLLFGNYSTisLGYAGLCECTKYMKGVSHT-DPRGKDFAL 548
WP_013498514 460 ALMCRHERlKG-TLSDAAPILWQYgal---arLKKGEPIDKLLYGGYSTisLGYAGLYECVKYMTGKSHT-DPEAKPFAI 534
WP_041738569 477 ALRLRHERlLG-TPSDAAPILWQYgal---arLSKGETIDRLLFGGYSTisLGYAGLYECVKYMTGHSHT-EKAGTPFAM 551
WP_014116946 462 ALMCRHNRlKG-TLSDAAPILWQYgal---arLQKGETIDKLLYGGYSTlsLGYAGLYECVKYMTGKSHT-DPEATPFAL 536
WP_009204371 465 ALRCRHERlKG-AVSDVAPILWQHgal---arLKKGEKIDKLLYDGYSTisLGYAGLYEMCVRMTGKSHT-SDEGKEFAL 539
WP_005934848 460 ALQARHQRlMG-TPSDAAPILWQYgal---arLKKGEKIDKLLFGGYSTisLGYAGLYECVKYMTGKSHT-DAGAKPFAL 534
WP_106056481 459 ALRLRHERlLG-TPSDVAPILWQYgai---arLKKGETIDKLLYNGYSTisLGYAGLCEMCYRMVGKSHT-TDEGREFAL 533
WP_015732220 603 KIIGHMREFCDKESERLGLNFSLLATPAEGLSGRFVRMDKKKFGIIPGvtDRDYYTNSFHVPVYYKISAFKKLSLEAPYH 682
WP_012802661 552 EVMQHMNDKCNTWKEEHDIDFSLYGTPLESTTYKFSKCLQRRFGIIEGitDKGYITNSYHVHVAEEIDAFNKLKFESQFQ 631
WP_013252350 552 SVMQRMNDKCAEWKAAEDIDYSLYGTPLESTTYKFSKCLQKRFGMVKGitDHGYITNSYHVNVREDIDAFTKLRFESDFQ 631
WP_013282300 549 KVMQFLNDKCAKWRAETNVAFSLYGTPLESTTYKFAKCLQKRFGIIPEvtDKNYITNSYHVHVTEQIDAFTKLKFESEFQ 628
WP_013498514 535 EIMQHMNDACKRWKEKENIDFSIYGTPLESTTYKFARCLQKRFGIIEGitDKSYITNSYHVHVTEKIDAFTKLKFESEFQ 614
WP_041738569 552 RVMQHMNDKCSAWKLAEDIDYSLYGTPLESTTYTFAKALQRRFGIIPGvtDKGYITNSYHVHVSEEIDAFDKLKFESEFQ 631
WP_014116946 537 SVMHRLNEATAAWKAKENIDFSLYGTPLESTTYEFAKCLQKRFGIIPGvtDKAYITNSYHVHVTEPINAFDKLKFESQFQ 616
WP_009204371 540 KVMQKLNDKCNEWKAAENISYSVYGTPMESTTYKFAKCLQKRFGIIPGvtDKNYITNSYHVHVTEEIDAFSKLAFESEFQ 619
WP_005934848 535 SVMQHMNDKCTEWKKAENMDYSLYGTPLESTTYKFAKCLQKRFGIVPGitDKNYITNSYHVHVSEPIDAFTKLKFESEFQ 614
WP_106056481 534 KVMQRLNDKCAEWKAAENISYSVYGTPMESTTYKFAKALQRRFGVIPHvtDKNYITNSYHVHVEEEIDAFQKLKFESDFQ 613
WP_015732220 683 ALTNAGHISYIELdGDPTQNLDAFEKIVKH-MAkvGIGYGSINHPVDRDPVCGFVGVIGD----------VCPRCGRSeg 751
WP_012802661 632 PLSPGGAISYVEV-PDMQDNLEAVMKVLHYiYD--NIMYAELNTKSDYCQVCGFDGEITIieddg-klvwECPHCGNRdq 707
WP_013252350 632 RLSPGGAISYVEV-PNMQDNLEAVVRVMQFiYD--NIMYAELNTKSDYCQVCGYDGEIQIveddg-klvwECPKCHNHdq 707
WP_013282300 629 ALSPGGAISYVEV-PDMNSNIEAVISVMKYiYD--NIMYAELNTKSDYCQCCGYDGEIKIvtdkdgklvwECPNCGNRnq 705
WP_013498514 615 HLSPGGAISYVEV-PNMQKNIPAVLKVIRFiYD--NIMYAELNTKSDYCQVCGYDGEIQIveddg-kliwECPQCHNRdq 690
WP_041738569 632 ALSPGGAISYIEV-PDMQDNLKAVVSVMRYiYD--NIMYAELNTKSDYCQECGFDGEIKIveddg-klvwECPRCGNRdq 707
WP_014116946 617 ALSPGGAISYVEV-PNMQDNLPAVLAVMEYiYN--HIMYAELNTKSDYCQVCGYDGEISIveddg-klvwECPKCGNRdq 692
WP_009204371 620 KLSPGGAISYIEV-PNMQDNIPAVLSVMKFiYN--NIMYAELNTKSDYCECCGYDGEIQIkedesgkliwECPNCGNTdq 696
WP_005934848 615 KLSPGGAISYVEV-PNMQDNLEAVISVLQFiYD--NIMYAELNTKSDYCQCCGYDGEIKIveddg-klvwECPKCGNRdq 690
WP_106056481 614 KLSPGGAISYVEV-PNMQDNIPAILEVMKYiHE--NIMYAELNTKSDFCEECGYSGEIKIvedaegklvwECPNCGNRnq 690
WP_015732220 752 haiSCEKLEELRKKFPGmpAFRGIR 776
WP_012802661 708 --tKLNVARRTCGYIGTq-FWNQGR 729
WP_013252350 708 --sKMNVARRTCGYIGTq-FWNQGR 729
WP_013282300 706 --dKMNVARRTCGYIGTq-FWNQGR 727
WP_013498514 691 --nKMNVARRTCGYIGTq-YWNQGR 712
WP_041738569 708 --eKLNVARRTCGYIGTq-FWNQGR 729
WP_014116946 693 --nRLNVARRTCGYIGTq-FWNQGR 714
WP_009204371 697 --dHMFVARRTCGYIGTq-FWNQGR 718
WP_005934848 691 --nKLNVARRTCGYIGTq-FWNQGR 712
WP_106056481 691 --dKMSVARRTCGYIGTq-FWNQGR 712
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