Conserved Protein Domain Family
VMA21

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pfam09446: VMA21 
VMA21-like domain
This presumed short domain appears to contain two potential transmembrane helices. VMA21 is localized in the ER where it is needed as an accessory factor for assembly of the V0 component of the vacuolar ATPase.
Statistics
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PSSM-Id: 462801
Aligned: 46 rows
Threshold Bit Score: 45.6059
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EHY54251             36 SVIYKLLGFTMAMIFFPIGSYFLSVNLVFGGkeiscpsapaVRYLHPdtsnsLGNATYAGAFAAIMANVVLVAYIIVA 113
XP_002073296        139 lIILMLLFYGSLIVLFPISVFFALKFIVLKN----------FFLITN-----MDIDIISVIGTVIAVHAAAGFYIYRV 201
Q9VCQ2              137 FIVLLLMSYCSLIIGFPIATFFALKFVVLKS----------Y---AH-----INADIISTICTVVAVHAAVGFYIYRA 196 fruit fly
XP_001844545         20 rnfrVVFFYCILIILLPVSTFFATKYVLFDG----------YFQLSS-----VSSNIYAAVAAVIALHIALGLYIYRA 82 
XP_001607695         11 QVFKTVLMHCIVIIAFPVISFFVSKIFIFDG----------ILGLST-----VTSNVYAAGVAVLVLHVALAAFIYRA 73 
XP_001689091         21 RTFKTVFLYCILIIALPVLTFFTSKHWIFDQ----------LLQLSS-----VSSNIYSAVSAVVALHGALFLFIYKA 83 
XP_002048110         32 SAFKVVLFYCSLIVFLPVVTFFALKGFLLER----------FFTMSD-----MKVNIGSAVGAVAALHIALGVYIYRA 94 
EDW34671             33 SSFKTVLFYCMLIVFLPVITFFLLKAVVLDG----------FFEMSE-----LKVNIFSAVGAVVALHIALGLYIYRA 95 
Q9VCQ2               46 ERMQRLLLFLTVFLLFPVVIFVIFKFLIMEP----------LYGNSD-----DNVGIGSGVATVIVMHVLVTGYILRL 108 fruit fly
WGS:AAPP:GF18026-PA  46 RRMQQLIIFPTVFFLCPVLIFFIFKFALLAP----------FVGFDD-----ANAAIGSAVATVIVMHVLIAGYTLRL 108
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