Conserved Protein Domain Family
VacB

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COG0557: VacB 
Exoribonuclease R [Transcription]
Statistics
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PSSM-Id: 440323
Aligned: 687 rows
Threshold Bit Score: 473.825
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013581757   6 YPqSDRDLIRFIERspsHRAGYKQLIRELGLGGGRERRLLLEQLARITLRGDLVKIDDG-QWALPratpdkterpgaprp 84  
WP_108125521   1 -------MLD------------------------------ANALAQL----------QSlKSDIQ--------------- 18  
WP_095986506   1 -----------MDS--------------------------------------------------P--------------- 4   
WP_095983112   1 -----------MDSs---------------L--------------------------S------P--------------- 7   
WP_011378237   1 MNfSIATLLTQFSEg--KFVAPKQLEKKLGCEDEDKSRKLQIILDALERLGLLTKDR-G-KYRRN--------------- 61  
WP_044290753   1 MEfSIATLLANFTDd--KLVARKLLEKKLGCEDDDSIQKLQIALDVLEKIGILAKER-G-KYRRL--------------- 61  
WP_002611359   1 -----------MDSs---------------A--------------------------R------P--------------- 7   
WP_012164530   1 MEfSISTLLNNFADd--KLLAPKALEKKLDCQASDGIRQLQITLEALEKVGILTKER-G-KYKRL--------------- 61  
WP_075999297   1 -------MLN------------------------------QDSLSQL----------KGlKSQME--------------- 18  
WP_043322480   1 -----------MDTs---------------A--------------------------S------P--------------- 7   
WP_013581757  85 dsgtwdrgtrphgriTRENLVAGKLDLHRDGFGFVRPNgsSKrE-D--DLFIPPHELNGAMQGDEVLVDEAPP-AVDGR- 159 
WP_108125521  19 ---------------SSQPRLSGRVKGTGRSFGFVVGD--DG---L--EYFLPPEGMARVFPGDKVTFLVEQQ--GDGK- 73  
WP_095986506   5 ---------------TS-RTVTGHIDVHHRGHGFLIvR--PSnTsEglSAFIPPPELRHHLADDVVSARITRA--EDGR- 63  
WP_095983112   8 ------------------RTVTGHVDVHPRGFGFLLvR--SSgAdPglSAFIPPAELAPYLTDDVVSATVSRA--EDGR- 64  
WP_011378237  62 ---------------EENEWVEARLRCSSKGFCFAIQDa-ED-A-E--DIYIREHQLNHAWNGDRVLVNVLREgSRR-Rs 120 
WP_044290753  62 ---------------SEDSLIEAKLRCSSKGFCFAIQDv-EA-A-E--DIYIRESHLSNAWNGDRVLVRVLKEgSRR-Rs 120 
WP_002611359   8 ------------------RPVTGRIDVHPRGFGFLVvQ--PPpSgEvlSAFIPPPELASFLADDTVSATVSQG--ADGR- 64  
WP_012164530  62 ---------------PEEGVVEGKLRCSSKGFCFAIQDq-DD-T-E--DIYIRESQLNTAWNGDRVLVKVTKEgRRR-Rs 120 
WP_075999297  19 ---------------AEKERAEAVVKGTQARYGFAVLD--DG---R--EVFIPPDEMLKVFPEDRVQVCIRPA--KDNK- 73  
WP_043322480   8 ------------------RTVTGRVDVHPRGFGFLTvQ--KPgTpEvlSAFIPPPDLNPLFAGDVVSATVTAS--GEGR- 64  
WP_013581757 160 RSGRIARILTRRNTTVVGIFHY--ARgrgsrgttpdsyntaN--FHYIVPLDERMTQPILIES--APDgqptlpaT-PAe 232 
WP_108125521  74 VRASLEALEESALDVFVGRYVE--RG---------------K--AQGVEPEDAGHAKWLFVPP--KKT-------A-DA- 123 
WP_095986506  64 WRASGLSVVHRPRQELYGEVVV--RE---------------E--RVLLQPDRDVGAGAWPL-E--AEG-------I-EV- 112 
WP_095983112  65 WSASGLSLVKRPRQEVFGEVVL--RD---------------S--RVFLQPDREVGRGDWPL-E--TQG-------T-EL- 113 
WP_011378237 121 PEGEVKLILERANSSVLARITEkaEG---------------Eg-F-RAVPLDDRLLCELDLES--NGL-------DlAA- 173 
WP_044290753 121 PEGEVRLVLERSNHTLLARIKQ--IE---------------Gg-F-RAVPLDDRLLFELKLRQ--NGI-------VlDN- 171 
WP_002611359  65 WTASGLSLLQRPREQVYGEVVL--RK---------------G--TPFLRIDREVASSDWPL-E---TG-------T-AV- 112 
WP_012164530 121 PEGEVRLILERSNPSVIARVKK--TE---------------AgeY-RAVPLDDRLLFELALHQetDGP-------DlEA- 174 
WP_075999297  74 TIADIEKLIDCPLGDFTGRCVR--KG---------------K--ALFVEPDLQQLSRWLFIPP--HAR-------N-GV- 123 
WP_043322480  65 WTASGLSLVERTRTVVYGEVVS--RK---------------G--AFFLRIDKEVSNTDWPL-D--PGT-------T-PV- 113 
WP_013581757 233 sqhrvlgeearrelsfdpslphfLEGLAVDVEVTSFPTESRPAQGRILEILGHPDAFGVDVEIVIRKHHLPYAFPANVLA 312 
WP_108125521 124 -----------------------QSGQWVKARVTRHPWETGKAQAEIEGILGAENEAGTWHRLAIEKYQLVSEFSAEELA 180 
WP_095986506 113 -----------------------QPGDAVVARIDED-------KVRLVRKLAp--gVDRSLERLLLRHGLRREFGPEAHA 160 
WP_095983112 114 -----------------------RAGDAVVAQVDTG-------TLRLLRRFEp--gVDLSLERLLVRHGLRRDFGPEARA 161 
WP_011378237 174 -----------------------NRDHLASVAVQRYPLAQLPPVGKVTQILGSDPESASPVDLIRCKHNLPADWSEAAIA 230 
WP_044290753 172 -----------------------AIDHLAHVQVLRYPLAQYPPLGKVVQILGSDAEAAADIDLVTCKHDLSRTFSDNVEE 228 
WP_002611359 113 -----------------------QTGDAVVARIVEG-------KAVLLHRLEp--gVDRSVARIIARHDLRRDFPPEVLE 160 
WP_012164530 175 -----------------------AIDQLVHVEIVRYPLGQLSPLGRVTQVLGSDAQSAADTELVFCKYDLPRSFPEDVLA 231 
WP_075999297 124 -----------------------QEGDYVRCAILRHPIRDGKPQAKILSVIGGEDTPGIENLYSMAKYRLSADWGASSRK 180 
WP_043322480 114 -----------------------QHNDAVVARIADG-------KVVLLYRLEp--gADRSLERVIARHGLHRDFPSEVVQ 161 
WP_013581757 313 EAAA-SAdqtvDTLTPEDL-SLRHDFRGLPIVTIDG--ETARDFDDAILVQPLp-NGNWQLQVHIADVSHYVRPGTDLDL 387 
WP_108125521 181 AADA-LD----ANLIEQLA-DTRSDLTDLPFVTIDG--ATTRDMDDALFAEEId-TG-WLLHVAIADPSAWFETNSALDN 250 
WP_095986506 161 EVPQ-VL----AR--PLTR-EGRRDLREVPTVTVDA--PITRIIDDALSVLPAggDGALRLFVSIADAAEFIPEGSALDR 230 
WP_095983112 162 EVPA-LL----AR--PHAL-GSRRDLRGVPTVTVDS--SSTRVIDDALSILPAggDGALRVFVSIADAAEFVPEGSALER 231 
WP_011378237 231 ALTD-LA----QTADANAI-QGRLDLRSVFTVAIAA--DDSRPLDVALSLQPGe-SGGWQVMVHTVEVAPYLPLQSDLDL 301 
WP_044290753 229 VAAK-LP----KRILKADR-KSRLDLTDKYTICICAnaDSSKVRENAISLEETe-EGNWLLGFHIADVSHYVKPDEALDR 301 
WP_002611359 161 EARA-VR----GV--PHAL-GARRDLRALPTVTVDA--PSTRDIDDAISVLPAgeDGALRLLVSIADVAEFVTEGSALDR 230 
WP_012164530 232 EAEA-LP----KKLRKADQ-KKRVNLLKVPTFTICDrtPNPTQLDHAFSVEKLk-GSKWRVGVHVTDLVYYLDPDSSIER 304 
WP_075999297 181 ELEKqL-----AECRPLEA-EYRQDLTDLEFISIDA--AKTQDIDDALYAQISd-DG-WTLFVAIADPTSYIPPDSDLQR 250 
WP_043322480 162 EALR-AK----EA--PHALgGSRRDLRSIPTVTVDA--PSTRDIDDAISVLPAgpDGAVRLLVSIADVSESVKENTPLDL 232 
WP_013581757 388 EARLRGTSVYFPDRSVPMLPPSLSSNMCSLRPDEDRLVLSCIAEID-NHGEVVDYQLCEGIIRSARRMTYTQVQSILDTs 466 
WP_108125521 251 AARKRLTTTYLPGQPLDMLPKRLAEDLCSLVPDAVRLALVFHLHVD-RDGTLSKLAITPARIRSTAKLSYTDVSRWLDG- 328 
WP_095986506 231 EARERATNVYLGDTLLPMLPEALAAGSLSLVPGEERLCVTVELRID-PEGRVTSVDVYESLLRSWARLSYTEVTAYLDQ- 308 
WP_095983112 232 EARERATNAYLADAMLPMLPEELSADWISLKPGEDRSCLTVELRLD-PEGRITSVDVYESLLRSWARLSYTEVAAWLDT- 309 
WP_011378237 302 EAQRHGIDLRLGETALPFLPPVLTQGVGRFAVGEDRRAVSLLIRVD-ATGAVQDYELQPSLVQLDQVLSPAEATDLLAD- 379 
WP_044290753 302 EALKRGRSVYLGKLVLPMLPDAVA-ARSSLVTGSDRLAISFLTTLDgETGEVLDWEIQPSVVNVDTDLNQKQASQVLGA- 379 
WP_002611359 231 AARERGTSVYLAGHVLPMLPEELSSHWLSLVPGEERRCLSVELRID-AEGHVTAADVSESLIRSWARLNYDEVAAYLDR- 308 
WP_012164530 305 QASQRGAAMFLGDTALPLFPETCIERIGALTAGKDHLTFSILVTLD-NEGEVLEFEIQPSVIHVDQHLAYEQVQEILDG- 382 
WP_075999297 251 DVAARGTSVYFHGDILPMLPEELSQETCALSEGADRPALVCKIAIN-DDGRVGEYEFIEATIRSRAKLSYYAVDKYLSG- 328 
WP_043322480 233 EARARATSVYLAGRVLPMLPEELSAHWLSLVPNEERHCLTVELRID-PDGRVTAADVYESLIRSWARLNYDEVAAFLDD- 310 
WP_013581757 467 sttpppgaprpdsgtwvsaylstdlspaesekhtRD-LETRL-QFLDLAPAFEQMYDLALKLNRKRHRRGSIDFDLPEPV 544 
WP_108125521 329 ----------------------------------EE-P------IPAQHWHLETLRACSNALNTWRQNEALVMADRPDYR 367 
WP_095986506 309 ----------------------------------GEvSE----PMARVREAMPWLRAAAARLAVARAGRGGIDQTRDEAH 350 
WP_095983112 310 ----------------------------------GEfSA----PMAPVREAMPWLRAAAARLAVARAGRGGIEMTRDEAF 351 
WP_011378237 380 ----------------------------------S--KA--KgE---GIKALKELQTIADLWRTQRRERGGFELTV--TP 416 
WP_044290753 380 ----------------------------------ET-KE--EpE---VVEMLQQLQALAIVLKEQRLARGSLQLNLPVLQ 419 
WP_002611359 309 ----------------------------------GAvSA----AMEPVREAMPWFRAASARLAVARAGRGGMELAREEAR 350 
WP_012164530 383 ----------------------------------DH-K---DkSL---ADAMQLFQTVSEALKKQRYDRGGFDLLLSTVP 421 
WP_075999297 329 ----------------------------------QN-EELM-----MHASPLEALYQVYRALRGNRETNHLVMEDRQEYR 368 
WP_043322480 311 ----------------------------------NSiSP----AMEPVREAMPWFRLASARLAVSRAARGGMTMSRDEAR 352 
WP_013581757 545 IR-FDPQ-GNMAAITRSERGWANRLIEEFMLTANECVAHWLEALG-PSIYRIHELPDAKRILDFEEVA-----ATYGQTL 616 
WP_108125521 368 IR-VDEQ-LAVTCVDREDRTTAHALVEESMLATNRIAAAWLADDR--ALFMTHPGFRGEREEELKGLLrecapSVADEDg 443 
WP_095986506 351 FT-FDEVtGEVSGIETERPTSAHALVERFMVAANEAIAGWLVERGlPAPFRVQGEPEPQAVADLDAFA-----LHSGFAA 424 
WP_095983112 352 FT-FDDVtGEVSGIETVRPTSAHALVERFMVAANEAIAGWLVERGvPALFRVQEGPDPRRVADLEVFA-----RQSGFAP 425 
WP_011378237 417 AI-GNDE-GALGVI--SRSPAIAGAVQEILIQANRLVTEHLQALElPVLYVGQRSPDLGSIQDAQRLA-----AGLGLAI 487 
WP_044290753 420 NP-FFDE-GASGCVTETD-SSVSSLLTELVLLTNQLMAIHLNALGiPAIWRVQGAPDPDDVQEMLKLA-----INLGVEL 491 
WP_002611359 351 FT-FDAGtGQVSGIENTPPTTAHQLIERFMVAANEAIASWMEDRGlPAVFRVQDEPDRQRVADLSAFA-----HHSGFEA 424 
WP_012164530 422 PQiMGDE-GDLGAVILASPTQAHSIIADLLVLANHLVLSHLQALAiPGVYQIQAPPDAQDLQDLLKLA-----DNIQLSL 495 
WP_075999297 369 WI-MDDN-KQIDHIEPFEKLLSQKLVEECMIAANRCAARFLTENNaGGPFVTHPGFRSDRIDEMRKFLtmhapEVAEADV 446 
WP_043322480 353 FT-FDTAtGAVSGLAGEKDTSAHNMIERFMVAANEAIATWLMTRGvPTVYRVHEQPDPQRVADVNAFA-----LHSGFAA 426 
WP_013581757 617 gfsslpvkkltmksdrrsnraaserhGG-RtrqaqsheipeSiPVTPLMYQKLTAKIAGTPEERILSYLMLRSLKQARYS 695 
WP_108125521 444 --------------------------N------------------QLDGYRRILRAARD-CTDFPLQKVLQKRLERGLWT 478 
WP_095986506 425 --------------------------GL-G-----------R-TLTPLSLAAFARQLSGVPEEAALRSVMFKALASSRYS 465 
WP_095983112 426 --------------------------AM-G-----------R-APTPLALAAFDRQISGTPEEPALRAVLRRALGSSRYT 466 
WP_011378237 488 --------------------------EVdEn---------eT-ELNRLALQQLSDATQTSELASLLDHLLLQTFKPSFYS 531 
WP_044290753 492 --------------------------AL-Pd---------dI-EIQPLDYQHLTKVFAESASEQVLTYLLQDTLKPPTYT 534 
WP_002611359 425 --------------------------GF-G-----------G-RLTPLALAAFDRQITGCAAEPALRSVLRRSLGFARYT 465 
WP_012164530 496 --------------------------GL-Qq---------eD-TVQPQDFQTFSQTFQTSERSAILFELLQSTLKPVQYS 538 
WP_075999297 447 --------------------------T------------------TVAGYQQIMRALSRPGQALPLRTMVNRLLTRAEIT 482 
WP_043322480 427 --------------------------GF-G-----------A-QITPLALAAFDRQISGAKAEAALRSVLRRSLGPSRYT 467 
WP_013581757 696 EKNEGHFALASPS-YTHFTSPIRRYPDLIVHRLIRAALH-AN--ANp------------------------Ngqpifstd 747 
WP_108125521 479 AQAAPHFGLGFEQ-YTTVTSPIRKYSDLTVHRLIKAKLN-DE--AFa--------------------------------- 521 
WP_095986506 466 VVPAPHFGLAARA-YVHFTSPLRRYADLAVHRALKHYLR-GR--RD---------------------------------- 507 
WP_095983112 467 VVPAPHFGLAAPA-YVHFTSPIRRYADLAVHRALKHYLR-GR--RD---------------------------------- 508 
WP_011378237 532 TLAVPHFSLGLET-YGHFVAPSQRYADLWLQRVILALFQqGRdrRSsrskegvnirhssshgqinwsvlppE-------- 602 
WP_044290753 535 TNQGGHFGLALPDgYLHCTSPMRRYPDLLMQRVYYSLIEnGRdrRNtrvkervnlrssnchgdinwnvlppE-------- 606 
WP_002611359 466 VVPSGHFGLAARR-YLHFTSPIRRYADLAVHRTLKQYLR-GR--RD---------------------------------- 507 
WP_012164530 539 AVSGPHFGLALVNnYGHFTSPLNRYGDLLNQRILHAVFTeGRdrRTsrakekvnlrhsdchgqiswnvlppE-------- 610 
WP_075999297 483 ASPAPHMGMALEH-YTNCTSPLRKYLDFLVHLQIKAILR-EQ--PAa--------------------------------- 525 
WP_043322480 468 VKPGPHFGLAAPL-YLHFTSPIRRYADLAVHRLIKAYLH-GR--RD---------------------------------- 509 
WP_013581757 748 pqpwsskrsstkpgaprlasetwvSTTLPPEELAAISLESSQSERRADDAERELMEWKKIKFMQDRVGEEFHATVLSCTK 827 
WP_108125521 522 ---------------------------IDNALVDTLNDRLGASRKAANEVDNHLRLQWLAQLSEQQPEQTWAATIVHINA 574 
WP_095986506 508 -------------------------FPHEDPDVERLSLHLNERVRRAQRAEKERHRLLEARVMAAHVGQEFTGHITRVRS 562 
WP_095983112 509 -------------------------FLHEDPDVERLAVHLNERTRATQRAEKERQRLLEARVMAAHVGREFTGRVTRVRG 563 
WP_011378237 603 ------------------------VQTELETDLKLLAQQLSEAEKRATEASADYQGLQKAAAAKACIGQTFAGVIRGVQS 658 
WP_044290753 607 ------------------------LQQELQADLARVITQINDREKEVQEAEADLEGLKRAALMKQRIGEVFSGVITGVQS 662 
WP_002611359 508 -------------------------FAHQDPAVEQLAVRLNARAKASSRAEQDRHRVLEARLMASHVGKSYPARITRVKP 562 
WP_012164530 611 ------------------------TQRHLDALITDAIPQLNEQADLARQACQDLTGLQKTKQMQTHTGEVLQGIITGIQS 666 
WP_075999297 526 ------------------------R--LEQSVLEALAERISTARAATLEAERWLAGKHLARVVERQEGKTFKARVAHVNS 579 
WP_043322480 510 -------------------------FVHEDPEIEKLSQHINVRARSANRAEADRHHELEARFMSTRIGQQFPARIVRVKP 564 
WP_013581757 828 YGFYVELD------------DLFIEGMVPIQSLseslpfgDPDRFFFRDTDRVIVASHSGR-VFKLGQRVHVLLDRIDRP 894 
WP_108125521 575 GGLIVQLD------------DNGASGFVDLRSG-------EEKF-SYDALRMLM---KSETrQFVLDQALTVRIQANDGQ 631 
WP_095986506 563 TGLLVQLD------------QPLVEGLLPLESL-------PGGPYAPDARETSLVG--PTR-DFTLGMPLRVRVAFTEEH 620 
WP_095983112 564 SGLLVQLD------------SPLVEGLLPTDSL-------PGGPYTPDERETALVG--SAR-TFPLGMPLRVRVASTDEG 621 
WP_011378237 659 YGFFVQIE------------ALQVEGLVHVSSL-------KDDWYEYRSRQQRLIGRKNRR-QFGLGDRVEVEIRNVDYY 718 
WP_044290753 663 YGFFVEIEvpsqeteeisniPLRVEGLVHVSSL-------KDDWYEYRARQQALFGRKNRA-SYRLGDRVAVQVKSVDYY 734 
WP_002611359 563 FGLLIQLD------------GMLVEGVVPMDSL-------PGGPFRPDARETSLVG--KER-SFTVGMPLMAKVVSTDEV 620 
WP_012164530 667 YGFFVRIE------------TLMVEGLVHVSSL-------KDDWYEYRSRQQTLVGRKNRC-QYRLGDRVDVEVKSVDYY 726 
WP_075999297 580 SGFNVRLD------------DNGLDGFVDLRKD-------PEKF-SYDKWTASL---TSTTrRFQLNDEVELRFIGVDRE 636 
WP_043322480 565 FGLVAQLD------------GMWVEGMVPAEGL-------AGGPYRPDTRELSMVG--KTR-TFTVGMPINVKVVSTDEQ 622 
WP_013581757 895 NR-RLQFALVPS-R-TPQG 910 
WP_108125521 632 KL-ELAL--VE-------- 639 
WP_095986506 621 PG-RVGLALVE-------- 630 
WP_095983112 622 LG-RVELALAG-------- 631 
WP_011378237 719 RQ-QIDLGVLPL-P-EAQS 734 
WP_044290753 735 RQ-QIDLVTVGN-D-DGAS 750 
WP_002611359 621 LG-RIEFALAE-------- 630 
WP_012164530 727 RQ-QIDLIVVGG-G-SEAP 742 
WP_075999297 637 NRyQAGFELVEGcGlK--P 653 
WP_043322480 623 LG-RVEFALVE-------- 632 
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