Conserved Protein Domain Family
PRK06187

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PRK06187: PRK06187 
long-chain-fatty-acid--CoA ligase; Validated
Statistics
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PSSM-Id: 235730
Aligned: 148 rows
Threshold Bit Score: 624.903
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
154174438   2 QYKYQNLYEMLSDVANQRFGCTAIFDDKQK----IKYGELKSSVDKAAMYLQAIGVKFGDKVGMAVVNSQEFIIAYFAVT 77 
160899759   1 --MQQTLGDTLAWPARYLPNKEALVAWEGGerrvWTYAQLDAEVNRHAHGLAELGIGHGDVVAAFLYNTPAFVFTMLAAA 78 
194291921   1 MTRGITLGDTLTWPARNLPRKTALVTGIGTgrraWTYAQLDAEVNRHAHALQSLGIGKGDVVAAFLYNTPAFVFTLLATA 80 
284165366   1 MSQHPTIGDTLEQTVDRYPDRDAIVYPRKDq--rWTYAEFDERVNRLANALADRGIEKGDRVATVLHNGSEMALTVYACA 78 
138894834   1 --MYVTIGDMFSQTVRKFPMREAVVEVATGr--rYTYAEWEVEVNRWANAFLEAGVRKGDRVSTVLYNTLELATALFACA 76 
239826720   1 --MYMTIGEVFAQTVRKFPKKEAVVDMAKGr--rYTYEQWEKEVHRLANALLEAGVQKGDRVSTVLFNTLELGTAFFACA 76 
261419521   1 --MYMTIGEMFSQTVRKFPNREAVVDAATGr--rYTYAEWEREVNRWANAFLEAGVRKGDRVSTVLYNTLELATALFACA 76 
297530509   1 --MYMTIGEMFSQTVRKFPNREAVVDAATGr--rYTYAEWEREVNRWANAFLEAGVRKGDRVSTVLYNTLELATALFACA 76 
56419850    1 ----MTIGEMFSQTVRKFPNREAVVDAATGr--rYTYAEWEREVNRWANAFLEAGVRKGDRVSTVLYNTLELATALFACA 74 
212639346   1 --MYLTIGEVFTQTVRKFPKKEALVDVRTGl--rYTYKQWAKEVDKLANAFLKAGVRKGDRVSTVLFNTAELATAFFACA 76 
154174438  78 AIGAVAVPMNTFLKSEEFSYILNDCGAEILFASSQLAKELAPLNELKQL--------QKIIWIGEVPkslqvtrlepkqn 149
160899759  79 RLGAIFNPINYRLAAQELAFILKDGAARALVFEHEGGEVAARAQALLKAegggtgagIEHWIFADDApadp--------- 149
194291921  81 RIGAVYNPVNYRLAAQELAYILNDGGARALLFEREGAAVVEKAAELAPG--------TTLRLYADADpa----------- 141
284165366  79 KLGAVFTPLNFRLPAGEIEYIVTDAEAELVLFESETREAVEGARPSLET--------VSEYVYIDDDree---------- 140
138894834  77 KIGAVFNPINFRLKAEEIAYILMDAEPKIVIFERSVEPQLAAISSRFPH--------VSFWSIDGDPp------------ 136
239826720  77 KIGAIFNPINFRLKSKEIAYILEDATPKVVLFEKAVEPQIASIHHEFPH--------ILFWYIDDDTp------------ 136
261419521  77 KIGAVFNPINFRLRAEEIAYILTDAEPKIVLFERAVEPELAAIHSRFPH--------VSFWSIDRDPp------------ 136
297530509  77 KIGAVFNPINFRLRAEEIAYILTDAEPKIVLFERAVEPELAAIHSRFPH--------VSFWSIDRDPp------------ 136
56419850   75 KIGAVFNPINFRLRAEEIAYILTDAEPKIVLFERAVEPELAAIHSRFPH--------VSFWSIDRDPp------------ 134
212639346  77 KIGAVFNPINFRLRPKEIAYILTDATPKIVLFEQAVEPQITAIHHEFPH--------ISFWIIDGQVp------------ 136
154174438 150 ldeeygesvylapalqqeggidaqyfslqgvnERNINFVDLLSHKYSLSIAKTPEIDDLVHIIYTSGTTGKPKGAMISYK 229
160899759 150 -----------------------------lpvWATQRLSALARGRSSAPPQAHVRESDPCILMYTSGTTGRPKGVLHTHR 200
194291921 142 ------------------------------paCATHRLDALAADQPDTLPAVMVDENDPCILMYTSGTTGRPKGVMHTHR 191
284165366 141 ------------------------------apEYATGFYDLLESGSTDRPDVHVEEDDVYAFIYTSGTTGRPKGVVHEHR 190
138894834 137 --------------------------------PFAKNAYEQVVQATDEAPHVHVEESDLYAIMYTSGTTGRPKGVMHRHR 184
239826720 137 --------------------------------SYAANYHALVSNAQTTAPSIEVFERDIYAMMYTSGTTGRPKGVLHRHR 184
261419521 137 --------------------------------PFAKNAHEQAARALGEAPRVHVDESDLYAIMYTSGTTGRPKGVMHRHR 184
297530509 137 --------------------------------PFAKNAHEQAARALGEAPRVHVDESDLYAIMYTSGTTGRPKGVMHRHR 184
56419850  135 --------------------------------PFAKNAHEQAARALGEAPRVHVDESDLYAIMYTSGTTGRPKGVMHRHR 182
212639346 137 --------------------------------TYAASYHEQIQCASNELPTIDVSENDLYAIMYTSGTTGRPKGVMHRHR 184
154174438 230 NIFSNIEGAHnrFIVRSSDRFIVFLPMFHSFTLTAMILlPMFVGASMVLIKSVfPFSNVLKQTLLKRVTVFLGIPAIYTA 309
160899759 201 SKLAHNALMHqtMQFTRDDVGLAMAPLNHTAELHTSFLpRLQAGATQVLLRRF-DVTEAWRLIHEERVSFFFAAPTMVTM 279
194291921 192 SKLQHNAMMHqaMMLSREDVGLSIAPLNHTAELHTSFLpRLQLGATQVLQRRF-DAGEAWQLVEAEGVTHFFAAPTMVAM 270
284165366 191 SMVEHNLLCIaeLDLTRDDVGLSIMPLYHCAELHCSLFaRVHRGATNVIHHEF-DPEAALEAIEAHGVTVLFAAPTAWNA 269
138894834 185 DMIEQSVVCQgvMRIRETDRGLAAAPLFHCAELHCCLLpRVHAGAASVILHHF-DAKLVLETIERERITLMFGAPTMWNM 263
239826720 185 DMIEQSMICNavMRIRDTDRGLVSAPMFHCAELHCCFLpRVHAGAANIILHHF-DPKLVLKTIEQEKITLLFAAPTMWNM 263
261419521 185 DMIEQSVICHgvMRIRETDCGLAAAPLFHCAELHCCLLpRVHAGAASIILHHF-DAKLVLETIERERITIMFGAPTMWNM 263
297530509 185 DMIEQSVICHgvMRIRETDRGLAAAPLFHCAELHCCLLpRVHAGAASVILHHF-DAKLVLETIERERITILFGAPTMWNM 263
56419850  183 DMIEQSVICHgvMRIRETDRGLAAAPLFHCAELHCCLLpRVHAGAASVILHHF-DAKLVLETIERERITIMFGAPTMWNM 261
212639346 185 DMIEQSLICNsvMRIRETERGLVTAPMFHCAELHCCFLpRVHAGATNVIVHHF-DPKQVLTVIEQEQITVLFAAPTMWNM 263
154174438 310 IGKAKIPwYFRWFNRIRLFISGAAPLAKQTIDDFKVKFpHARLVEGYGLSECSPVVAANLYDKQ--KSLSVGPALEGYEV 387
160899759 280 LLADPIA-SPEQAPALRLVEYGGASMAPHLIREWTRKV-GSDLVQVYGTTEMGPCMSILLPREQlsHAGSAGLPSMGHDL 357
194291921 271 LLNHPDA-EARDVSSLRLVEYGGASMAPHLIREWDRKV-GAGLVQVYGTTEMGPCMSVLYPHEQlsHAGSAGLPALGHEL 348
284165366 270 LSLTAAE-TDVDVSSLRIGLYGAAPMPERVLENCMDHL-CEDYVQAYGMTEIGPAGVFQPPEDQvpKQGSAGLPALNHRV 347
138894834 264 ILQENVS--GYDISSLRLGLYGAAPMAPALVRQCQERL-GIGLIQAYGMTEMGPAVTFLLEDEQlkKAGSAGRACVNHEI 340
239826720 264 LLQENLR--AYDLSSLRLGLYGAAPMAPVLVKECKERL-GIDLIQAYGMTEMGPAVTFLLEDEQltKAGSAGRACLNHEV 340
261419521 264 ILQENVS--GYDLSSLRLGLYGAAPMAPALVRQCQEQL-GIELIQAYGMTEMGPAVTFLLEDEQlkKAGSAGRACLNHEI 340
297530509 264 ILQENVS--GYDLSSLRLGLYGAAPMAPALVRQCQEQL-GIELIQAYGMTEMGPAVTFLLEDEQlkKAGSAGRACLNHEI 340
56419850  262 ILQENVS--GYDLSSLRLGLYGAAPMAPALVRQCQEQL-GIELIQAYGMTEMGPAVTFLLEDEQlkKAGSAGRACLNHEI 338
212639346 264 LLQEKLS--DYDLSSLRIGLYGAAPMAPVLVKECKERL-GIDLIQAYGMTEMGPAVTFLYEEEQltKAGSAGRACLNHEI 340
154174438 388 KIVNDEM----------IEVgtGEIGEIIVKGDCVMQGYFGMPN-ITDETIING---WLKTGDLGKVDDEGFIYIVDRKK 453
160899759 358 IVARLREdnaptdpaeaCLP--GEVGEILVRGPCMMAGYLNRPD-ANTRALAHG---WYHTGDLGHIDDDGYLWIRDRID 431
194291921 349 VVARLREdgaptdpsqpCAP--GEVGEVLVRGPCMMQGYLNRPE-ANARALAHG---WYHTGDLGSLDADGYLWIRDRID 422
284165366 348 RVVDPDAdp-------aAAVetGEIGEILISSPCTMREYWNRPEaTARSLREADgttWYYTGDLGYRDEDGYLFVVDRKD 420
138894834 341 RVVRAREdgpsd-pddvLPP--GEVGEIVMRGPCMMAGYYKREE-ATEKALYKG---WYHSGDLGYVDEDGYLYVADRVD 413
239826720 341 RIVKPREdgpsd-pddvLPP--GEVGEIIMRGPCMMVGYYNREE-ATAKAMYKG---WYHSGDLGYMDEEGYLYVADRVD 413
261419521 341 RVVRAREdgpsd-pddvLPP--YEVGEIVMRGPCMMAGYYKREE-ATEKALYKG---WYHSGDLGYLDEDGYLYVADRVD 413
297530509 341 RVVRAREdgpsd-pddvLPP--YEVGEIVMRGPCMMAGYYKREE-ATEKALYKG---WYHSGDLGYLDEDGYLYVADRVD 413
56419850  339 RVVRAREdgpsd-pddvLPP--YEVGEIVMRGPCMMAGYYKREE-ATEKALYKG---WYHSGDLGYLDEDGYLYVADRVD 411
212639346 341 RIVKPREdgpsd-pddiLPP--GQVGEIIVKGPCMMVGYYNRED-ATEKAMYKG---WYHSGDLGYMDEDGYLYVADRVD 413
154174438 454 DLIISKGINIYPREIEEVLYKLEEVEAAAVIGIKDEHADEEVAAFIQL-KEGMDLDEKQVRDYL--KKHLANFKIPKSIY 530
160899759 432 YMINSGAENVYPREVEDALVEHADVLEVAVIGEADERWGQIVAAHVVA-KPGATPTAEALDAFLvhGDRLAAYKRPRRYH 510
194291921 423 YMINSGAENVYPREVEDALIEHPGVLEVAVLGEPDPTWGQVVGAYVVA-RGEETLSADQLDAFLlqGDRLAAYKRPRRYH 501
284165366 421 DMIVSGGENVYPAEVEDVLFAHDAVEEAAVVGEPDEEWGERVVAYVVVdG----VDAAALDEFVleSDRLADFKRPRTYY 496
138894834 414 DMIISGGENVYPREVEDVLYEHPGVLDVAVLGEPDELWGEKVVAFVV--KKDALLTADELEQFCktSDRLAPYKRPRAYY 491
239826720 414 DMVISGGENVYPREVEDVLYEHPGVLDVAVVGEPDEIWGEKVVAFVV--KKDPNVTEEDLEQFCktSDRLAPYKRPRAYY 491
261419521 414 DMVISGGENVYPREVEDVLYEHPKVLDVAVLGEPDELWGEKVVAFVV--KKDDLLTADELEQFCktSDRLAPYKRPRAYY 491
297530509 414 DMVISGGENVYPREVEDVLYEHPKVLDVAVLGEPDELWGEKVVAFVV--KKDDLLTADELEQFCktSDRLAPYKRPRAYY 491
56419850  412 DMVISGGENVYPREVEDVLYEHPKVLDVAVLGEPDELWGEKVVAFVV--KKDDLLTADELEQFCktSDRLAPYKRPRAYY 489
212639346 414 DMIISGGENVYPREVEDVLYEHEGVLDVAVLGEPDALWGEKVVAFIV--KKDQQLTAEQLEAFCkqSDKLAPYKRPRAYY 491
154174438 531 FAEQLPRNATGKVLKRVLKEQVKDKI 556
160899759 511 FREALPKTASGKIQKQLLRVVVAA-- 534
194291921 502 FLEALPKTTSGKIQKHLLRAAGAT-- 525
284165366 497 FVDELPKNPSGKIQKFKLREDEADVD 522
138894834 492 FIDVLPRNASGKIQKFLLRERLKQQA 517
239826720 492 FVDALPRNASGKIQKFLLREQVKNAA 517
261419521 492 FIDALPRNASGKIQKFLLREQLKKQA 517
297530509 492 FIDALPRNASGKIQKFLLRKQLKKQA 517
56419850  490 FIDALPRNASGKIQKFLLREQLKKQA 515
212639346 492 FVEALPRNASGKIQKFLLREQMKKMA 517
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