Conserved Protein Domain Family
lgt

?
TIGR00544: lgt 
prolipoprotein diacylglyceryl transferase
The conversion of lipoprotein precursors into lipoproteins consists of three steps. First, the enzyme described by this model transfers a diacylglyceryl moiety from phosphatidylglycerol to the side chain of a Cys that will become the new N-terminus. Second, the signal peptide is removed by signal peptidase II. Finally, the free amino group of the new N-terminal Cys is acylated by apolipoprotein N-acyltransferase. [Protein fate, Protein modification and repair]
Statistics
?
PSSM-Id: 273128
Aligned: 7 rows
Threshold Bit Score: 267.351
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
P75547   1 MNPSVSSRPPW-STAFYLGp-gFPIQWYGIIVAIGIAFGILMFVLKLIYF---YKIQDNSFYFFIFIAVLTMVLGARAWY 75  Mycoplasma pneumoniae...
P37149   1 MTSSYLHFPEFdPVIFSIGp--VALHWYGLMYLVGFIFAMWLATRRANRPg--SGWTKNEVENLLYAGFLGVFLGGRIGY 76  Escherichia coli
P44930   1 MNSNYLLLPHFdPSIFTLGdsnIGLRWYGLMYLLGFVFARWLAVRRANRPn--SGWTVDQVDSLLFNGFMGVFIGGRVGD 78  Haemophilus influenza...
O25609   1 MNAWNTIYDQFnPIAFSLGs--IEVHWYGLAYACAIVTAFYMALRMIQKDpkrFPIERKEFESYFLWAELGIVLGARIGY 78  Helicobacter pylori 2...
O34752   1 MNEAIE--PLN-PIAFQLGp--LAVHWYGIIIGLGALLG-LWIAMRESEK---RGLQKDTFIDLVLFAIPIAIICARIYY 71  Bacillus subtilis sub...
P72846   6 FFGQFQ--SPG-PVMFQIGg--FALRWYGFLIASAVIIG-LNLCQWLGQK---RGINPDLFNDLVIWLVVAAIPSARLYY 76  Synechocystis sp. PCC...
P47332   1 MN-----RPSW-STAFNIGg-gFPIQWYGIIVSIGIIFAILMFVFKLIYC---YKLQDNSFYFFIFIAVLTMVLGARLWS 70  Mycoplasma genitalium...
P75547  76 FLIEA---VDGRSSGSNFFDFRNG--------GLAIQGGVLLTTLAGIIYFnvflnmkttktkttakllnnknqiktvyV 144 Mycoplasma pneumoniae...
P37149  77 VLFYNf--PQFMADPLYLFRVWDG--------GMSFHGGLIGVIVVMIIFA----------------------------R 118 Escherichia coli
P44930  79 VFFYNl--DHFLQEPLYLFRVWEG--------GMSFHGGLIGVIVAMIWTS----------------------------Y 120 Haemophilus influenza...
O25609  79 ILIYEpnsGYYLTHFWQIFNPFDShgnfvgirGMSYHGGLVGFLIASYLYS----------------------------R 130 Helicobacter pylori 2...
O34752  72 VAFEW---DYYAAHPGEIIKIWKG--------GIAIHGGLIGAILTGYVFS----------------------------R 112 Bacillus subtilis sub...
P72846  77 VAFEW---PRYAQHWLNIFAIWQG--------GIAIHGALIGGTIAILVFS----------------------------R 117 Synechocystis sp. PCC...
P47332  71 FVIG-----DSNFANNNFFDFRNG--------GLAIQGGILLTSIVGVIYFnfflnsktnktktiaellnnkneikavyV 137 Mycoplasma genitalium...
P75547 145 ERNISVFVMLDLIAPCVLIGQAIGRWGNFFNAEVYGAALVGskndtlsaanTTWGFLRILMp------------kVWDGM 212 Mycoplasma pneumoniae...
P37149 119 RTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPN----------FPFAMLFPGSrtedilllqtnpqwQSIFD 188 Escherichia coli
P44930 121 SQKRNFWQTADFVAPLIPFGLGLGRIGNFINLELWGR-ETN----------VPWAMIFP--------------------N 169 Haemophilus influenza...
O25609 131 KDLKKLLIYLDLIAISLPLGYVFGRIGNFLNQELVGRIVPKd---------SHLGQIIG--------------------I 181 Helicobacter pylori 2...
O34752 113 VKNLSFWKLADIAAPSILLGQAIGRWGNFMNQEAHGEAVSRa---------FLENLHLPEF--------------IINQM 169 Bacillus subtilis sub...
P72846 118 YHQLSFWNLLDVLTPAVILGQAIGRWGNFFNSEAFGAPTN-----------LPWKLYIPFA--------------NRPLN 172 Synechocystis sp. PCC...
P47332 138 ERNISVLVMLDLIAPCVLIGQAIGRWGNFFNQEVYGFALAGtmndpqalanTQWGFLKILMp------------kVWDGM 205 Mycoplasma genitalium...
P75547 213 FINGSFRIPLFLIESFFNTifFVFIYFVMDHIKGIRS------GTIGFSYFLATGIVRLILETQRDEAFKYNT----SIV 282 Mycoplasma pneumoniae...
P37149 189 TYGVLPRHPSQLYELLLEG--VVLFIILNLYIRKPRPm-----GAVSGLFLIGYGAFRIIVEFFRQPDAQFTGawvqYIS 261 Escherichia coli
P44930 170 DPLLLPRHPSQLYEAFLEG--LVLFTILNIFIKKPRPm-----ASVAGLFLIGYGVFRFIVEYVREP--E-VEnffgIIT 239 Haemophilus influenza...
O25609 182 MVDNELRYPSQLIEAFLEG--VIVFLMVMWAKKHTKTh-----GLLIVVYGLGYSLMRFIAEFYREPDSQ-MGvyflNLS 253 Helicobacter pylori 2...
O34752 170 YINGQYYHPTFLYESLWSf--VGVIVLLLLRRANLRR------GEMFLIYIIWYSIGRYFIEGMRTDSLMLTDslriAQV 241 Bacillus subtilis sub...
P72846 173 LTSYAYFHPTFLYESVWNl--GIFAILIALFFYGLRNpekiktGTITCVYLIGYSLGRVWIEGLRLDSLMLGPlr-iAQV 249 Synechocystis sp. PCC...
P47332 206 WIDGQFRIPLFLIESFFNTifFVLIYFVMDFIRGVKS------GTIGFSYFLATGIIRLILENFRDQTFYFQT----SIT 275 Mycoplasma genitalium...
P75547 283 FSALLILVGIVGIIYCQTLAIKLRGyfWTYFF 314 Mycoplasma pneumoniae M129
P37149 262 MGQILSIPMIVAGVIMMVWAYRRSP--QQHVS 291 Escherichia coli
P44930 240 RGQALCLPMIIGGAFIMAWAYSRK---SAVIK 268 Haemophilus influenzae Rd KW20
O25609 254 MGQILSLFMVIVSLGILLYATKNSKk-IKENQ 284 Helicobacter pylori 26695
O34752 242 ISIVLIVLAVAAIIFRRVKGYSKEr--YAE-- 269 Bacillus subtilis subsp. subtilis str. 168
P72846 250 VSITLVLLGTAGIVWLYLLQKNLPd--WSERK 279 Synechocystis sp. PCC 6803 substr. Kazusa
P47332 276 TSILFIVVGILGIFYCQFIHVKLRNyfWTYFF 307 Mycoplasma genitalium G37
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap