4N31


Conserved Protein Domain Family
sigpep_I_bact

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TIGR02227: sigpep_I_bact 
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signal peptidase I, bacterial type
This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking]
Statistics
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PSSM-Id: 274044
Aligned: 30 rows
Threshold Bit Score: 98.455
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4N31_A        27 YVFGV--MIINTNDMSPALSAGDGVLYYRL---------------TDRYHINDVVVYeVDNTLK---------------V 74  Streptococcus p...
AAO80666      88 FVLKTssYPIAGQSMKPTLNAGERVLVQR----------------TKQVARYDVIAFkAPLASKgt------------yV 139 Enterococcus fa...
AAS69099      38 FLFQI--YFISGYSMAPSYKEGDLILVTKFgfptrig-kweisfvESKVNRFDVLVLdGFEEELs--------------L 100 Leptospira inte...
P72364        24 FVIVG--HVIPNNDMSPTLNKGDRVIVNKIkv------------tFNQLNNGDIITYrR---GNei------------yT 74  Staphylococcus ...
AAK34129      26 FVFST--FKVSPETANTYLKSGDLVTIKKN----------------IQPKYKDFVVYrVG--KKd-------------yV 72  Streptococcus p...
AAS11830      25 CVFDV--KKVSGPSMEPSLKDGDCVFIFKFaygikhplnnkyifrWARPKSGDIIVYrKDGHFT---------------I 87  Treponema denti...
AAL96937      35 FQYIFgvMIINTNVMSPALSAGDGILYYRLt---------------DRYHINDVVVYeVDNTLK---------------V 84  Streptococcus p...
WP_010887963  35 FAFTL--ARVDGESMEPSLHSRELLLLLKYprwlr-----awglgGDYLQHGDVVIFkAPADSPyayetlygvrhrpynI 107 Deinococcus rad...
WP_002656888  28 FLSf---YIVKGESMTPAIFEKNWIVNHKFayglrikkhqkylllWKTPQKNEMVLIkDPITNKi-------------aI 91  Lyme disease sp...
WP_010925431  27 FFQFFsiIKISGNSMFPTFKDGSLKLFKKTnq---------------nLNLFQIVVFnK---NDnl------------yV 76  Mycoplasma pulm...
4N31_A        75 GRIAAQAGDEVSFTQeGG-LLING-----HPPEKE------VPYLTYPHSSGPNf---------PYKVPTGTYFILNDYR 133 Streptococcus p...
AAO80666     140 KRIIGVPGDRIWVNE-GK-LYLSE-----EPIASDne---aLPENASRFDLSEEaaaq---lrlFQKIPAGHYFVLGDNR 206 Enterococcus fa...
AAS69099     101 KRVVGLPGDYFRFEN-DR-ILIND-----SPLQETflkpgfKTIAPSLSMIPMTaakgnvpigdtgRIPPGYFLMLGDNR 173 Leptospira inte...
P72364        75 SRIIAKPGQSMAFRQ-GQ-LYRDD-----RPVDASy-----AKNRKIKDFSLRNfke-----ldGDIIPPNNFVVLNDHD 137 Staphylococcus ...
AAK34129      73 SRVIAVEGDSVTYMD--DiFYLNNmvesqAYLEKMkahylnHAPFGTLYTDDFTvati--tadkYQKVPKGKYLLLNDNR 148 Streptococcus p...
AAS11830      88 KRCLGISEEPIEFSKkLGyNYDYS-----MKVSGKni---pLTAIQFRNLGGMSdk-------eKVRVPAGYVLALGDNL 152 Treponema denti...
AAL96937      85 GRIVAQAGDEVSFTQeGG-LLING-----HPPEKE------VPYLTYPHSSGPNf---------pYKVPTGTYFILNDYR 143 Streptococcus p...
WP_010887963 108 KRVIGLPGDLIAFRD-GE-LWRNG-----HKVAESy-----ASTEGYVNde------------gPLRVPPGKVWVMGDNR 163 Deinococcus rad...
WP_002656888  92 KKIFAIPGEKFKQIEkNT-ICIHDl---nFKIDENi-----LKKN----TKK---------------IPEDHYLVIGENK 143 Lyme disease sp...
WP_010925431  77 KRIIALPGDNLIFEN-GK-VFRND-----QDITNl------FDPNELTLEKKLV-------------VPNNAYFVIGDNT 130 Mycoplasma pulm...
4N31_A       134 EE--RLDSRYYGALPINQIKGKISTLLRVRG 162 Streptococcus pyogenes
AAO80666     207 TH--SSDSRtFGFVEIQAIEGIVVFKMAPFK 235 Enterococcus faecalis V583
AAS69099     174 EN--STDSRNYGLVPFQKLRGRVWIFL---- 198 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130
P72364       138 NN--QHDSRQFGLIDKKDIIGNISLRYYPFS 166 Staphylococcus aureus subsp. aureus Mu50
AAK34129     149 KN--TNDSRRFGLINASQIKGLVTFRVLPLS 177 Streptococcus pyogenes M1 GAS
AAS11830     153 KE--SHDSRDYGFVLVDGIYGKVFIWKK--- 178 Treponema denticola ATCC 35405
AAL96937     144 EE--RLDSRyYGALPINQIKGKISTLLRVRG 172 Streptococcus pyogenes MGAS8232
WP_010887963 164 RTgaSLDSRSYGPVDLRDVAGPVAWRLWPAP 194 Deinococcus radiodurans
WP_002656888 144 QI--SLDSRDYGFIKIDNILGKIIYYF---- 168 Lyme disease spirochete
WP_010925431 131 TQ--STDSRhFGFVFDQEIIAKY-------- 151 Mycoplasma pulmonis
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