Conserved Protein Domain Family
MSMEG_0569_nitr

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TIGR04046: MSMEG_0569_nitr 
flavin-dependent oxidoreductase, MSMEG_0569 family
Members of this protein family belong to a conserved seven-gene biosynthetic cluster found sparsely in Cyanobacteria, Proteobacteria, and Actinobacteria. Distant homologies to characterized proteins suggest that members are enzymes dependent on a flavinoid cofactor.
Statistics
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PSSM-Id: 274942
Aligned: 12 rows
Threshold Bit Score: 712.566
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EEI37524       7 HPVVIVGAGQAGLSVSWYLGRAGVDHLLVESKT-PTHAWADSRWDNFTLVTPNWHCRLPGYVY----DGPDPDGFMTRDE 81  Gordonia bronch...
EAQ75652      25 VPVVVIGAGQAGLSVASCLQQQGLTPVVLERHR-VAHSWQHQRWDSFCLVTPNWQCRLPEFPY----DGDDPEGFMGRDA 99  Synechococcus s...
EEI98034       7 VPVVVIGAGQAGLATSYLLKQARVEHVVLERHR-PGHAWRSERWDSFCLVTPNWQCQLPGHPY----AGSDPDGFMVKDE 81  Haliangium ochr...
WP_011615421  18 YGVIIVGGGQAGLSMSYFLKQAGIDHLIIEKHT-VTHTWRTQRWDAFCLVTPNWQCALPGYPY----QGDDPHGFMKKDE 92  Cupriavidus nec...
WP_012162714   5 YSVIIVGGGQAGLSVSYCLGERQIDHIIFEQDQ-IAHSWRNKRWDSFCLVTPNWQCQLPGFSY----PGDDPNGFMQKEQ 79  Acaryochloris m...
WP_012306291   5 YPVIIVGGGQAGLALSYLLKQNNIDHLIFEKHK-IGHAWRNERWNSFCLVTPNWQCRLPGFPY----AGPDPTGFMAKEE 79  Synechococcus s...
WP_011145551  13 YDVVIIGGGQAGLCISHYLQKAGIDHVVLEKESeLTHSWCHKRWNNFTLVTPNWQCLLPEHPY----QGNDPDGFMKKHE 88  Photorhabdus lu...
WP_011863250  13 CSVIIIGAGQAGLSIAHSLQKKGIKPLILEKNY-VGFSWKEQRWDSFCLVTPNWQCTLPDYQY----SGKDPNGFMDKEN 87  Prochlorococcus...
WP_012228476   8 IPVIIIGGGQAGLSLSWYLCREQVGHVVFEART-ACHSWDDERWDNFCLVTPNWQCALPGHPY----AGTDPHGFMVKDE 82  Gluconacetobact...
WP_011650431  10 YSAVVIGGGQAGLSASYYLKSHGIDHVVFEKKT-VAHKWKNERWDAFCLVTPNWQCQLPDHPY----DGTDPHGFMVKDE 84  Rhizobium legum...
WP_011981320  12 HPVVVVGAGQAGLSLSWHLTRRGVDHVLLERGT-TAHEWRDGRWDAFTLVTPNFQCRLPGWSYtgefAGTDPDGFMERDE 90  Kineococcus rad...
WP_011607021  20 LPVAVIGAGQAGLAMSWHLTADGVDHAVLERDT-ALHTWSDARWDSFCLVTPNWQCRLPGHAY----DGPDPNGFMVKSE 94  Frankia alni
EEI37524      82 VVTWLQGWLATFTPPVREHTTVTRLTETG--------AHG-FELTlngpDGIESVTCEQVVVATGGYPLPVIPPYAGTLD 152 Gordonia bronch...
EAQ75652     100 IVDYLRRFAYHAAVPVREGIAVERLQPLE--------TGG-YRLS----TSDGVIETPQVVIATGAYHRPRRHPLAARLP 166 Synechococcus s...
EEI98034      82 IAAYLEAYVASFDPPLRQGVEVQRVSRA---------ADG-YRVQ----TGDVAYLCDALVVATGGYHSPRVPACARLVP 147 Haliangium ochr...
WP_011615421  93 ITAYLDGFIRTVGAPVLEHTEVRQVKARA--------QGG-FAVV----TSQGAFTADQVVVASGGYHTPIVPRMAERLP 159 Cupriavidus nec...
WP_012162714  80 IVDYIEAYARSFNPPVREGVSVQRVRKNP--------ISDvFEVS----TSIGEFSADQIVVATGGYHRPRIPGMAQRLP 147 Acaryochloris m...
WP_012306291  80 IVSYLEAYARSFNPPIREGVTVSKVSSAG--------T-K-FAVK----TSIGNYTADQVAIATGGYHVPKIPPIAAQLP 145 Synechococcus s...
WP_011145551  89 IVAYLDEFIEKTNPPAILNIQVEHVKKVA--------AHE-FVIE----TNHGTTTAKQLVVAAGGYHTPIYPKLSDTLP 155 Photorhabdus lu...
WP_011863250  88 IVKYLKKYSEFVKADILEGIEVKHLVK-K--------NEK-YFIS----TNRGNFEADQVVIATGAYHVPNRHPLSERLP 153 Prochlorococcus...
WP_012228476  83 IIAYVKGFTDSFTPPLREHTRVTSVTRHE--------GGG-YRVV----AGGEAWHARHVVIASGAYHDAVIPGYAGAID 149 Gluconacetobact...
WP_011650431  85 ILAYVDRFVKKVDAPIFEQTGVTSLEKHG---------GL-FRLE----TSAGAVTADAVVIATSLYADPAIPRAGERLP 150 Rhizobium legum...
WP_011981320  91 VHRFVTEYARSFAAPVREGVAVTSLRQHG---------GG-FALS----TSAGEFSADQVVIATGGYHVPVVPAAAERLP 156 Kineococcus rad...
WP_011607021  95 IVAWLDGYRASFDPPVREHTAVNSLRPLGdgpgaadpAGG-FAVR----TTAGELVADQVVVATGGYHTPAIPRLAERLP 169 Frankia alni
EEI37524     153 PSVTQIHSEQYFNADQLPDGAVLVVGSGQSGTQIAEDLHLAGRDVHLAIGNAPRVARFYRGRDSMTWLADMGLYDTPTQQ 232 Gordonia bronch...
EAQ75652     167 ARLLQLDARDYRRPDQLPDGPVLVVGSGQSGCQIAEDLFLAGRRVHLSVGSAPRSPRRYRGKDVVDWLDRMSYYDTPIEQ 246 Synechococcus s...
EEI98034     148 ADVHQLHSGSYRNPAALPPGAVLVVGSGQSGCQIAEDLHLAGRQVHLAVGSAPRCARRYRGRDVVAWLDEMGHYRRPIDS 227 Haliangium ochr...
WP_011615421 160 ASVRQLQSSEYRNPESLPEGAVLVVGSGQSGAQIAEDLHLAGRKVYLAVGEAPRCARFYRGRDVVDWLADMKYYDLPVTE 239 Cupriavidus nec...
WP_012162714 148 AGIRQLHSSEYKNPESLADGAVLVVGTGQSGCQIAEDLHLSGKQVHLCVGSAPRSPRQYRGKDVVDWLDQLGYYDLTIED 227 Acaryochloris m...
WP_012306291 146 RELQQIHSVQYKNPQDLPD-EVLIVGTGQSGCQIAEDLHLAGKTVHLVTGSAPRAPRRYRGKDVVEWLERMGYYDLPIDQ 224 Synechococcus s...
WP_011145551 156 NHVKVMHSEEYLNVEQLPKGAVLVVGSGQSGAQIAEDLHLAGKKVYLSTGNAPRCARFYRGKDVVKWLFDMGYYETTVKH 235 Photorhabdus lu...
WP_011863250 154 TNILQIDAREYKNANTLPDGPVLVVGSGQSGCQIAEDLFFEKRKVHLSVGSAPRSPRMYRGRDVVDWLDRMGYYSMPIGE 233 Prochlorococcus...
WP_012228476 150 SSIMQVHSQAYRSAAQLPEGAVLVVGSGQSGAQIVEDLHLEGRKVHLCVGSAPRVSRFYRGRDVVDWLADMKFYDLTVDD 229 Gluconacetobact...
WP_011650431 151 EDITQIHTAAYRNADQLPDGGVIVVGSGQSGCQIAEDLHLAGRKVHLVTGNAPRCARFYRGRDVVDWLSDIGQYDITV-E 229 Rhizobium legum...
WP_011981320 157 RDVVQLHSSAYRSAQRLPEGAVLVVGSGQSGAQIAEDLHLAGRRVHLAVGNAPRCARTYRGRDCIAWLEDMGTYDVTAGE 236 Kineococcus rad...
WP_011607021 170 ADLHQVHSARYRRPADLPAGPVLVVGTGQSGAQIAEDLHLAGRQVHLAVGYAPRFARRYRGRDVIAWMHDTGHYARPVTD 249 Frankia alni
EEI37524     233 YPGGKAAQEKTNHYVTGRDGGRDIDLRRFATEGMRLYGALEDGKDSTLRFAPTLTAALDKADAVYNSICADIDRYIDANG 312 Gordonia bronch...
EAQ75652     247 HPDPRSVRRKTNHYLTGRDGGREIDLRRRALEGMVLHGRLEEISVSGFRFAPDLAANLDGADAVYRRIRASIDTYIESNG 326 Synechococcus s...
EEI98034     228 FPDPDEVRRKTNHYVTGRDGGHDLDLRRFATEGMRLYGTLDDIDEHGLRFRPDLRSNLDAADDVYRRINASIDAYIAEHD 307 Haliangium ochr...
WP_011615421 240 HPLREGVRDNTNHYVTGRDGGRDIDLRRFATEGMELYGLLDDYLEGQLRFAPDLRRNLDDADATYNRINASIDKFIAERG 319 Cupriavidus nec...
WP_012162714 228 HPQKEQVRTKTNHYVTGRGGGREIDLRHFALEGMQLYGRLTDIREAQLTFHANLRENLDQADAVAESIKGTIDAYIDKHQ 307 Acaryochloris m...
WP_012306291 225 HPQKEMVRHKTNHYVTGRDGGRDIDLRRFAQQGMHLYGRLQSITRQTLHFGKDLKHNLDQADATVVRIQRNIDKFIADNN 304 Synechococcus s...
WP_011145551 236 HRYSEEVRNSTNHYVTGRDGGRDIDLRKFALEGMQLFGHFDDFKEGQFWFKPNLSENLDLADATYNRINASIDEYLEKNN 315 Photorhabdus lu...
WP_011863250 234 HDDPKSVRNKTNHYLTGRDNGREIDLRKRAIEGMNLHGRLKEITIDNIQFSNDLSKNLDGADSVYCRIRNSIDEWISKNN 313 Prochlorococcus...
WP_012228476 230 HPLRDGARDKTNHYVTGRHGGHDLDLRLFAKQGVGLHGTLRTIRDEVALFQPDLKDNLDDADRTNADIKASIDAYIAREG 309 Gluconacetobact...
WP_011650431 230 HGGMTKKKHDTNHYLTGRDGGRDIDLRKFALEGIALYGRMSGVAAGRMLFEPNLKANLDGADRVYNGINALIDRHIAEKG 309 Rhizobium legum...
WP_011981320 237 VPGGAAAQEKTNHYMTGRDGGRDIDLRAFAREGMGLHGRLEDVRDGVARFAPTLEQALDHADSVMESIKDVIDRHISARG 316 Kineococcus rad...
WP_011607021 250 RPVEERSADRTNHYVTGRDGGRDIDLRAFARQGMVLHGRLTGVDAGRFAFADDLAANLDAADEVYNGINELIDAHIAANG 329 Frankia alni
EEI37524     313 ID-A-PPATRYQPVWAPDTDPTELDLAAAGITSIVWAIGFRPDYRWIEASAFDGAGRPMQTRGITQVPGLSFIGLPWMHT 390 Gordonia bronch...
EAQ75652     327 LE-A-PEDPAYEPCWQPPPQDPPLDLGDEPLAAVIWCTGYRSDFRWVEVPIFDGAGEPVHQRGVTPAAGLYVLGLPWLHT 404 Synechococcus s...
EEI98034     308 ID-A-EPGSVYEPVWTPAEEDASLSWSDAAITSVIWCTGFGANYEWIDLPVFDDAGHPVHERGVTDAPGLFFVGLPWLHT 385 Haliangium ochr...
WP_011615421 320 IE-A-SPPSVYEPVWTPPAERTELDPQAAGIGSIIWCIGFRPDFSWLEVPVFNGRGYPGHERGVTAHAGLYFLGLPWLHT 397 Cupriavidus nec...
WP_012162714 308 IE-A-PVEAPYCPVWEPATEPTALNLEAAHITTVIWSIGYDMNYSWVEIPVFDGKGYPGHDRGVTGVKGLYFVGLPWLYT 385 Acaryochloris m...
WP_012306291 305 IT-A-PPEAHYQPVWEPELEPSSLNLKETNIGAVIWATGFRLNFSWIDLPIFNELGEPLHDRGVTAVDGLYFLGLPWLYT 382 Synechococcus s...
WP_011145551 316 IA-TdEPASVYQPVWQPEQEITHIDLAKENMTSVIWCIGFKPDYSWLDLDIFQTNGYPKHDRGITIDPNVTFIGLPWLYT 394 Photorhabdus lu...
WP_011863250 314 IE-A-PKGEIYTPCWEPTEDVKGTQLECKNLAVVIWCTGYKSDFSWVDISVFDGTGIPVHERGVTQSSGLYFIGLPWLYT 391 Prochlorococcus...
WP_012228476 310 IS-A-PVEAPYVPVWEPDGENAPLDLKAAGITSIVWCIGFRPDYRWIDVPVFNGANKPVWNRGVTGQAGFYFLGLPWLHT 387 Gluconacetobact...
WP_011650431 310 IE-A-PAGSPYVPVWEPEAEIAELDLKAEGITSVIWATGFSPDWSFVGLPIFDGNAYPVHRRGVTAVDGVYVLGLPWLWT 387 Rhizobium legum...
WP_011981320 317 ID-A-PNEARYVPVWRPEQEVTELDLAAAGITSVVWSVGYRADHRWVELGVFDGRGRPRQTRGVTGTPGLFFLGLPWMHT 394 Kineococcus rad...
WP_011607021 330 LDvA-VGPSRYTPVWQPPSATGP-ALAVTDVAAVVWATGFTRDYRWLHAGIFDGAGHPQHRRGVTAVPGLYLLGLPWLHT 407 Frankia alni
EEI37524     391 WGSGRFLGIDRDARHVADHV 410 Gordonia bronchialis DSM 43247
EAQ75652     405 WGSGRFCGVGSDAAYLAGLI 424 Synechococcus sp. WH 5701
EEI98034     386 WGSGRFCGVGDDARFIVSQV 405 Haliangium ochraceum DSM 14365
WP_011615421 398 WGSGRFSGIARDAEYLAALI 417 Cupriavidus necator
WP_012162714 386 WGSGRFSGIARDVRYLADYV 405 Acaryochloris marina
WP_012306291 383 WGSGRFSGVARDAEYLATQI 402 Synechococcus sp. PCC 7002
WP_011145551 395 WGSGRFLGIDQDAAYVVQHI 414 Photorhabdus luminescens
WP_011863250 392 WGSGRFCGVKDDANFLADII 411 Prochlorococcus marinus
WP_012228476 388 WGSGRFSGISRDAAWLAGQI 407 Gluconacetobacter diazotrophicus
WP_011650431 388 WGSGRFLSVGRDAEHVVGHL 407 Rhizobium leguminosarum
WP_011981320 395 WGSGRFAGIARDAEFLADQL 414 Kineococcus radiotolerans
WP_011607021 408 WGSGRFAGIARDAAYLAEQV 427 Frankia alni
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