Conserved Protein Domain Family
dnaK

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PRK00290: dnaK 
molecular chaperone DnaK; Provisional
Statistics
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PSSM-Id: 234715
Aligned: 1009 rows
Threshold Bit Score: 932.207
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
29654590    1 MAEIIGIDLGTTNSCVAVMEGGKVRVIENAEGS----RTTPSIVAYTKDGEVLVGASAKRQAVTNADRTLYAIKRLIGRR 76 
48477912    1 MSKIIGIDLGTSNSAAAVVISGKPTVIPAAEGVslggKAFPSYVAFTKDGQLLVGEPARRQALLNPEGTVYAAKRKMGTD 80 
16082111    1 MSKIIGIDLGTSNSAAAVVISGKPTVIPSSEGVsiggKAFPSYVAFTKDGQMLVGEPARRQALLNPEGTIFAAKRKMGTD 80 
13541319    3 MSKIIGIDLGTSNSAAAVVISGKPTVIPSSEGVsiggKAFPSYVAFTKDGQMLVGEPARRQALLNPEGTIFAAKRKMGTD 82 
148643169   6 KEKIIGIDLGTSNSAASVLVGGKPTVVPSAEGAsqygKAFPSYVAFTDDGQMLVGEPARRQAVTNPENTISAIKRSMGTD 85 
282164689   1 MSKIIGIDLGTSNSEAAVLEGGKPTIIPSAEGA----RLFPSYVAFTKTGERLVGEAARRQAVTNPERTVLAIKRKMGTD 76 
288561295   6 KEKIIGIDLGTSNSAASVLVGGKPTVIPSAEGAsqygKAFPSYVAFTEDGQQLVGEPARRQAVTNPENTISAIKRKMGTD 85 
304315414   4 KEKILGIDLGTSNSAAAVLIGGKPTIIPSAEGAsqygKSFPSCVAFTEDGQMLVGEPARRQAVTNPENTITAIKRSMGTD 83 
84490297    3 EEKVIGIDLGTSNSAAAALIGGKPTIIPSAEGAtqygKSFPSYVAFSDDGEVLVGEPARRQAVTNPENTISAIKRHMGSN 82 
116754043   1 MSKIIGIDLGTSNSAAAVLIGGRPTIIPSAEGTslggKAFPSYVAFTKDGQVLVGEPARRQAITNPEGTITGIKRKMGTD 80 
29654590   77 fddnvvqkdikmvpykiikadngdawV--EVKDKegksqKLAPPQISAQVLIKMKKTAEDYLGHEVKDAVITVPAYFNDS 154
48477912   81 --------------------------YkyKIFGK-----EYTPQQISAFILQKIKRDAEAFLGEPVTDAVITVPAYFNDN 129
16082111   81 --------------------------YkfKVFDK-----EFTPQQISAFILQKIKKDAEAFLGEPVNEAVITVPAYFNDN 129
13541319   83 --------------------------YkfKVFDK-----EFTPQQISAFILQKIKKDAEAFLGEPVNEAVITVPAYFNDN 131
148643169  86 --------------------------YkvTIHGK-----QYSPQEISAFILQKIKKDAESFLDEKVEKAVITVPAYFDDN 134
282164689  77 --------------------------HkvDIDGK-----KYTPQEISAMILSKIKQDAEAFLGEKISKAVITVPAYFNDN 125
288561295  86 --------------------------YkvTIQGK-----QYTPQEISAKILQKIKKDAESFLGEPVEKAVITVPAYFDDN 134
304315414  84 --------------------------RkvKVQGK-----EYTPQEISAFILQKIKKDAEAFLGEEIKKAVITVPAYFDDN 132
84490297   83 --------------------------YtvNIKGK-----DYTPQEISALILQKIKKDAEAFLGEPVKKAVITVPAYFDDN 131
116754043  81 --------------------------YkvKVFGK-----EYTPEEISAHILRKIKQDAEAFLGEKVEKAVITVPAYFNDN 129
29654590  155 QRQATKDAGKIAGLNVKRIINEPTAAALAYGMDK-KkGd-RK--IAVYDLGGGTFDISIIEIaevdGEHQ-FEVLATNGD 229
48477912  130 QRQATKDAGAIAGLNVRRIINEPTAACLAYGIDKlN-Qt-LK--IVIYDLGGGTLDVTIMDF----GQGV-FQVLSTSGD 200
16082111  130 QRQATKDAGTIAGFDVKRIINEPTAAALAYGVDKsG-Ks-EK--ILVFDLGGGTLDVTIMDF----GDGV-FQVLSTSGD 200
13541319  132 QRQATKDAGTIAGFDVKRIINEPTAAALAYGVDKsG-Ks-EK--ILVFDLGGGTLDVTIIEI----SKRPnVQVLSTSGD 203
148643169 135 QRTATKDAGTIAGLDVVRLVNEPTAASLAYGIDKq--Ed-DDvnIMVYDLGGGTLDVTIMEF----GGGI-FEVKSTSGD 206
282164689 126 QRQATKDAGTIAGLEVLRVINEPTAAALAYGLDK---TgtQK--ILVFDLGGGTLDVTIMEM----GEGV-FEVLSTSGD 195
288561295 135 QRTATKDAGTIAGLDVVRLVNEPTAASLAYGIDKqD-Dd-DDvnILVFDLGGGTLDVTIMEF----GGGV-FEVQSTSGD 207
304315414 133 QRTATKDAGTIAGLDVVRLVNEPTAASLAYGLDK---Ed-EDmvIMVFDLGGGTLDVTIMEF----GGGV-FEVRSTSGD 203
84490297  132 QRTATKDAGKIAGLEVLRLVNEPTAASLAYGLDKt--De-EDvnILVFDLGGGTLDVTIMEF----GEGI-FEVKSTSGD 203
116754043 130 QRQATKDAGTIAGLDVVRIINEPTAAALAYGLDK---GgeQK--IMVFDLGGGTLDVTIMEM----GEGV-FEVKSTSGD 199
29654590  230 TFLGGEDFDLRLIDYLAGEFKKDEGVDLHNDPLALQRLKEAAEKAKIELSSSQQTDVNLPYITADASG-PKHLNIRLTRA 308
48477912  201 THLGGTDMDEAIVNFLADNFQRENGIDLRKDHSAYIRLRDAAEKAKIELSTVLETEINLPYITATQDG-PKHLQYTLTRA 279
16082111  201 TRLGGTDMDEAIVNYIADDFQKKEGIDLRKDRSAYIRLRDAAEKAKIELSTTLSTDIDLPYITVTNSG-PKHIKMTLTRA 279
13541319  204 TQLGGTDMDEAIVNYIADDFQKKEGIDLRKDRGAYIRLRDAAEKAKIELSTTLSSDIDLPYITVTSSG-PKHIKMTLTRA 282
148643169 207 TQLGGTDMDNVLLKYLSDEFEKENGINLMDDDQAVQRLREAAEKAKIELSTTLTTEVNLPFITMGKDGsPKNLIVSLTRA 286
282164689 196 TQLGGTDMDNRIIDYIANSFQKENGIDLRKDKMAMQRLRDAAEKAKIELSSTLQTNVNLPFITADQNG-PKHLDMTLTRA 274
288561295 208 TQLGGTDMDNAIMKYLADEFKAETGIDLMNDDQAVQRLREAAEKAKIELSTTLTSEVNLPFISMGADGkPHNLINNLTRA 287
304315414 204 TQLGGTDMDNAIMNYLADEFKKETGIDLMEDDQAVQRLREAAEKAKIELSTTLTTEVNLPYITVAQDG-PKHLIKTITRA 282
84490297  204 TNLGGTDMDTALMKYIAEEFKKENGVDLLNDDQAAQRLREAAEKAKIELSTTLTTDINLPFITATQAG-PLHLNMSLSRA 282
116754043 200 TQLGGRDMDERLLDYIVEKFRQETGINLRNDVMAMQRLREAAEVAKIELSSMLQTTINLPYITADASG-PKHLNMTITRA 278
29654590  309 KLESLVEDLVERTIEPCKVAIKDAGLKVSEIDDVILVGGQTRMPKVQEAVKNFFGKEARKDVNPDEAVAIGAAIQGAVLS 388
48477912  280 KFEELIAPIVDRSKVPLDTALEGAKLKKGDIDKIILIGGPTRIPYVRKYVEDYFGRKAEGGVDPMEAVAMGAAIQGAVLA 359
16082111  280 KLEELISPIVERVKGPIDKALEGAKLKKTEITKLLFVGGPTRIPYVRKYVEDYLGIKAEGGVDPMEAVAIGAAIQGAVLK 359
13541319  283 KLEELISPIVERVKAPIDKALEGAKLKKTDITKLLFVGGPTRIPYVRKYVEDYLGIKAEGGVDPMEAVAIGAAIQGAVLK 362
148643169 287 KLEELVDDIVKKSGKPMQQALDDAKMSKSDIDKIILVGGPTRMPIVQKYVEKFIGKTIERGIDPMECVSMGAAIQGGVLA 366
282164689 275 KLEELVREVVDRCYAPMRQAISDAKLTATNIDHIILVGGPTRMPMVQEMVRKFFGKEPERGIDPMECVAMGAAIQGGVLA 354
288561295 288 KLEELVDPIVNKCGQPIKQALDDAKMTKNDINKIILVGGPTRMPVVQKFVENYIGKPVERGIDPMECVAMGAAIQGGVLA 367
304315414 283 KLEELVDPIVQRCAGPMEQALKDAKMTREDVDKIILVGGPTRMPIVQKFVEDFIGKPVERGIDPMECVAMGAAIQGGVLA 362
84490297  283 KLEEIVDPIIQKCGAPIKQAIDDAKLENNEIDRIILVGGPTRMPSIQQYVEDFVGQKVERGIDPMECVASGASIQGGVLA 362
116754043 279 KLEELIQDVLERCRGPMEQALSDAKLSKSDIDKIILVGGPTRMPAVQEFVKRVMGKDVERGVDPMECVAMGAAIQAGVLA 358
29654590  389 GEVKDVLLLDVTPLSLGIETLGGVMTKLIEKNTTIPTKANQVFSTADDNQTAVTVHVLQGEREMASANKSLGRFDLSDIP 468
48477912  360 GEVKDIVLLDVTPLTLGIETLGGVMTPLIPANTTIPTKKSQIFTTAADMQTTVTIHVVQGERPLAKDDVSLGMFNLDGIP 439
16082111  360 GEIKDIVLLDVTPLTLSVETLGGIATPIIPANTTIPVRKSQIFTTAEDMQTTVTIHVVQGERPLAKDNVSLGMFNLTGIA 439
13541319  363 GEIKDIVLLDVTPLTLSVETLGGIATPIIPANTTIPVRKSQVFTTAEDMQTTVTIHVVQGERPLAKDNVSLGMFNLTGIA 442
148643169 367 GEIKDLVLLDVTPLSLGIETLGGVSTTLIERNTTIPTKKSQIFSTAADNQPSVDINVLQGERKMAADNTSLGRFQLVGIP 446
282164689 355 GEVKDLLLLDVTPLSLGIETFGAVFTKLIERNTTIPTRKSQVFSTAADNQTSVEIHVLQGERPMASDNTTLGRFHLIGIP 434
288561295 368 GEIKDLVLLDVTPLSLGIETLGGVSTTLIERNTTIPAKKSQIFSTAADNQPSVDIHVVQGERKMAADNTTLGRFQLVGIP 447
304315414 363 GEIKDLVLLDVTPLSLGIETLGGVFTKLIERNTTIPTKKSQIFSTAADNQTSVDIHVLQGERPMAADNTSLGRFQLVGIP 442
84490297  363 GEIDDLVLLDVTPLSLGIETMGGVATKLIERNTTIPTKKSQIFTTAADGQTSVDIHVVQGERPMANDNTTLGRFQLVGIP 442
116754043 359 GEVKDILLLDVTPLSLGVETLGGIMTRLIERNTTIPTRKSQIFTTAADNQTSVEIHVLQGERPLAKDNISLGRFTLVGIP 438
29654590  469 PAPRGVPQIEVTFDIDANGILHVSAKDKATGKEQSIVIKASSGLSDEEVEKMVKDAEAHRDSDRKFHELVDARNQADAMI 548
48477912  440 PAPRGVPQIEVTFDIDANGILNVSAKDLGTGKQQSISITATNKLSKDEIERMKKEAEQYAEQDKKAKEEIETINNAETLA 519
16082111  440 PAPRGVPQIEVTFDIDSNGILNVTAVDKATGKKQGITITASTKLSKEEIERMKKEAEQYAEQDRKAKEQIELLNNAESLA 519
13541319  443 PAPRGIPQIEVTFDIDSNGILNVTAVDKATGKKQGITITASTKLSKDEIERMKKEAEQYAEQDRKMKEQIETLNNAESLA 522
148643169 447 PAPRGVPQIEVTFDIDANGIINVSAKDKGTGKEQAITITSSTKLSDEEIEQKIKEAEMNAEADKQKQEEIEVRNNADSLI 526
282164689 435 PAPRGIPQIEVTFDIDANGIMNVKAKDLGTGKEQAITITASTKLSKDQIDRMMKDAEKFASEDAKKKEKAEVTNNADSIL 514
288561295 448 PAPRGMPQIEVTFDIDANGIINVTAQDKGTGKEQSITITSSTKLSDEEIEKAVKEAEMNAEADKKKQEEIEVRNNADSMI 527
304315414 443 PAPRGVPQIEVTFDIDANGILNVSAKDLGTGKEQAITITAPNKLSEEEIKQKIEEAKKHAEEDRRKQEEIEIRNNADSMI 522
84490297  443 SAPRGTPQIEVTFDIDANGIINVSAKDKGTGKEQQITITSSNKLSDEEIEQKVKEAEAHAEEDKKRQEEIEIRNTADSLV 522
116754043 439 PAPRGIPQIEVTFDIDANGILHVSAKDLATKKEQRITITAPHRLSKEEIEQKVKEAERYAQEDARRREEIETRNQADNLI 518
29654590  549 HAAEKSV--KDLGSEVSADEKSAIEKAVNELKEAMKGNDKDAIEAKTKALTEHSSKLAERVYAK------KGG------- 613
48477912  520 YTAEKTI--NDAGDKIDESSKESVRSIVKDLRDAISSKDINKIKELSEKLTKEIQEIGTKMYQS------QAT------- 584
16082111  520 YSVEKTL--NDAGDKVDKETKERLTNEVKDLRKAIEEKNTENVKTLMDKLSKDIQEVGAKMYQQ------ASA------- 584
13541319  523 YSVEKTL--NEAGDKVDKETKDRILSEVKDLRKAIEEKNMDNVKTLMEKISKDIQEVGTKMYQS------ASS------- 587
148643169 527 YTSEKAL--EELKDKVSDDEKEKVEKLVGELRDLVAGDDIAAIKEKSDELSEVVQGISAKIYQE------AQA------- 591
282164689 515 YAAQKTV--AEAGDKITADQKDKINKGIEALKEAQKTDDMNKIKAETENLTKVVNEAATVMYQQ------AAQayqqqqq 586
288561295 528 YTAEKTIneEEIKDKVSDEERTNIERLVAELRELISGDDIPAIKDKTDELTKVVQDIGARIYQE------AAA------- 594
304315414 523 YTAEKTL--EELGDKVPSDKKETIEKQVSELRELIAGDDVQAIKAKTEELTKTVQEIGAVIYQQ------AAQ------- 587
84490297  523 YTADKTL--EELKDQLGEDKQTLIKDQQQELKDAIEKDDIDLIKEKSDALDKTIQEIGAEIYQQ------AAQ------- 587
116754043 519 YTTEKML--KEAGDVATSEQRERIEKAISELRDALSGKDVQEIKSKMEKLQNAVYELSAAMYQRaaqsqsGSAtgs---- 592
29654590  614 ----A----Agappggea---egepqaqaGG-KKEDVVDAEFEEV-KDEK 650
48477912  585 ----Q----Gtsqnss--------qnnnsqN-NNGDTVDADFKESk---- 613
16082111  585 ----N----Tqqsaqs--------nsqnsgS-SDGKTVDAEYKEKs---- 613
13541319  588 ----T----Tqtgsgn---------qnsskQ-ENDKTVDAEYKEKs---- 615
148643169 592 ----Q----Aqaqqqadpn---agaqsnssD-DDDGTIDADYEVKdD--- 626
282164689 587 akqqQqaqpN-------------------GGgKDPNVVDAEFEVK-DEKK 616
288561295 595 ----A----QqaaqgaaggagpdpsagpsnD-DDDGTIDAEFEEKd---- 631
304315414 588 ----Q----Qaenta-----------sqgeN-QGDDTIDADFEVKn---- 613
84490297  588 ----A----Qqqaqqqa------dqsdstqS-DNDDTIDADFEKK----- 617
116754043 593 ---------------------------asGStSGGKTVEADYEVV-NDDK 614
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