Conserved Protein Domain Family
McrB

?
COG1401: McrB 
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms]
Statistics
?
PSSM-Id: 441011
Aligned: 162 rows
Threshold Bit Score: 146.453
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_066850818 297 RDYlpgqrnapfeqrghpatamriratgvvtqvsddglsvkvdwtpltepklwwlytnndtiwrlpvekkeaarrlagfi 376 
WP_011274428 117 ENIieletd----------------------------------------------------------------------k 126 
WP_083825933 155 iefleqirekdfgnkinsiinerillvnknidnylkeiknkiqtqeerlkelenivsekefeikeleilrnkyielgiln 234 
WP_051120440     --------------------------------------------------------------------------------     
WP_045473360 200 ENFhahlqewfelaredalkiqqtmvhtysvn------------------------rsptaviplrgpfeglknldikkp 255 
WP_071479613 223 vasvrealtkveaelaaiavekrsveadidrlreartvlearnahleqktataggssietddplrelkvvpqvvsvlrdw 302 
WP_083957698 259 STLdarlahlkaeiarregrtvdgetge--------------------------------tdplrelketppvitamrtw 306 
WP_087455678 215 wfedsilnpsqeilfvgsdiyqkmesalldapaltrdnalepiqaeepaaeaeqplkaeekvqpvspapavrseeaakge 294 
WP_096300121 132 aqlaeaktteetlaeaiaqlerqlreggakvdaidacaakrraeldkkltelealikakgermvalrlidpadmtrlfps 211 
WP_106719945 525 QNFdpcpaftdldqstei----------------------------------------------------yekdlekreg 552 
WP_066850818 377 yedesQDLDWFr-------------NHKYWrdr------fgdSAAKVLSMAK---PTNLILYGPPGTGKTYRTALEAVRL 434 
WP_011274428 127 ktendELERKFlk----------hfMNKLsnenlv--yspkdILNFHTAMKT---SKLVILSGMSGTGKSKLIKAYANSL 191 
WP_083825933 235 ednvnekkeeiikeeyidikdkkeqidyiqkylalnkglyyddhilkrfflalhtnqIIILSGEPGTGKTSLVRGFSEAI 314 
WP_051120440   1 -------------------------------------------------MKI---GSLVVLSGLSGTGKSKLVRAYAKAL 28  
WP_045473360 256 itttvITTHKPikngtlsptypiieKEATkekikt-iyskevLDAVMAASFT---KNILILTGSPGVGKSSLAIDLID-- 329 
WP_071479613 303 keseiieenDAlh----------rvQLHFratglt--ypertLRAFHTAMKVnesTQMAVLAGISGTGKSQLPRQYAAGM 370 
WP_083957698 307 nnaprENEADAik----------rvERRLrakgld--ypartLRAFHAAMKVnetTQMAVLAGISGTGKSQLPRQYAAGM 374 
WP_087455678 295 anagsagEEQFin----------dfIKTAtnrgll--yserdLINFHTAMKS---STLVILAGMSGTGKSRLVEVYGQAL 359 
WP_096300121 212 etevdersghdfsedlganwkqlasyvqsylwrrgmhytsaqLQDYLALLRT---NDLIVLAGDSGSGKTSLVKSVAEAL 288 
WP_106719945 553 fkvkeTSLNDLvn----------fvVEYARnsrlhlsytpedIATFVSGMGA---SKLSILQGMSGTGKTSLPKIFSEAI 619 
WP_066850818 435 CDgdaddgdddegraalmerygelvKEKRIEFVTFHQNFGYEDFVEGLRPTTgsadgqtAGgfELKPEP-GiFRRIADRA 513 
WP_011274428 192 G------------------------LKDNFKFIPVSPSWSEDSDIIGYADTL-------NM--IYRPDDhG-LIETLIQA 237 
WP_083825933 315 SA--------------------------KHKIISVQPNWTDNQDLLGFYNPI-------EN--VYVPTP---FLDAIIEA 356 
WP_051120440  29 QL-----------------------GQEQLNFVSVRPFWQDDSDLLGYADTI-------NS--IYRAGDsG-LVDTLIEA 75  
WP_045473360 330 -------------------------DYERKLIVSVGSTWRGREDLLGYVNPI-------SN--EFEPTD---FTKFLCKA 372 
WP_071479613 371 GI--------------------------GFLQVPVQPRWDSPQDLMGFYNYV-------EG--RFRPTD---MARALWAM 412 
WP_083957698 375 GI--------------------------GFLQVPVQPRWDSPQDLMGFYNYI-------EG--KFRPTD---MARALWAL 416 
WP_087455678 360 GL-----------------------DPEQLRIIPVSPSWTDDADLIGYVDSI-------HN--VYRPGDsR-LIDTLVTA 406 
WP_096300121 289 GG--------------------------KCTVVPVKPNWTSSEDLLGYYNPI-------EK--RFHPTQ---FLSALLEA 330 
WP_106719945 620 YG--------------------------NIDIIEVESSWKDKNELLGYYNEF-------SM--KYTPKK---FTLALYKA 661 
WP_066850818 514 aapvmkadaafslddrsvfklslgeagkaewewvfedsleegyaifgfknvdwsderfrdrdailrelherfpdekltvq 593 
WP_011274428     --------------------------------------------------------------------------------     
WP_083825933     --------------------------------------------------------------------------------     
WP_051120440     --------------------------------------------------------------------------------     
WP_045473360     --------------------------------------------------------------------------------     
WP_071479613     --------------------------------------------------------------------------------     
WP_083957698     --------------------------------------------------------------------------------     
WP_087455678 407 e------------------------------------------------------------------------------- 407 
WP_096300121     --------------------------------------------------------------------------------     
WP_106719945     --------------------------------------------------------------------------------     
WP_066850818 594 ngdvkspdrfrnrinegdvvivskglnafraigvvegsyeyaprpdgrychrrkvrwlwddpegvdvreisekrfsldtv 673 
WP_011274428     --------------------------------------------------------------------------------     
WP_083825933     --------------------------------------------------------------------------------     
WP_051120440     --------------------------------------------------------------------------------     
WP_045473360     --------------------------------------------------------------------------------     
WP_071479613     --------------------------------------------------------------------------------     
WP_083957698     --------------------------------------------------------------------------------     
WP_087455678     --------------------------------------------------------------------------------     
WP_096300121     --------------------------------------------------------------------------------     
WP_106719945     --------------------------------------------------------------------------------     
WP_066850818 674 yevpksrlniteierlvnaaaasevedE----S------AE-----REPHVLIIDEINRANISKVFGELITLLEPDKRLg 738 
WP_011274428 238 ---------------------------K----L------NP-----DKLFIICFDEMNLARIEHYFSQFLSLLESDVE-- 273 
WP_083825933 357 ---------------------------K----E------NQ-----DRLYILCLDEMNLSHVEYYFSEFLSKIQSDKI-- 392 
WP_051120440  76 ---------------------------S----K------HK-----DKLYLVCFDEMNIAKVEHYFSQFLSVLEMDTE-- 111 
WP_045473360 373 ---------------------------EtawrK------ND-----KRTYVVIFEEFNLSQPEYWFADILVRSQYPEEq- 413 
WP_071479613 413 ---------------------------D----El----nNPegaleDRMLMILLDEMNLARVEYYFSDFLSRLESRPA-- 455 
WP_083957698 417 ---------------------------D----ElnnddaEQ-----DRMMMILLDEMNLARVEYYFSDFLSRLESRPRPd 460 
WP_087455678 408 --------------------------dE----K------NR-----DKLYVVAFDEMNLSRVEHYFSKFLSVLEASPG-- 444 
WP_096300121 331 ---------------------------S----R------NP-----GVPHFICLDEMNLARVEYYFADFLSLLESRDSLp 368 
WP_106719945 662 ---------------------------A----L------NK-----EIFTIILLDEMNLSRIEYYFSDFLSLMENEEE-- 697 
WP_066850818 739 qgnALT-V---------------------------------------RL------------------------------- 747 
WP_011274428 274 ---NRK-Lqly----------------------------------nkeLggk---------------------------- 287 
WP_083825933 393 -------Ldlyskkiydenlkelnm------kwekylkyenkeslkeELsneefnef-----------------lalkrr 442 
WP_051120440 112 ---YRK-Inly----------------------------------nddLtsr---------------------------- 125 
WP_045473360 414 --eKLRmI---------------------------------------ELgg----------------------------- 423 
WP_071479613 456 -----A-Ievt--------------------------------------------------------------------d 461 
WP_083957698 461 dvg----------------------------------------------------------------------------d 464 
WP_087455678 445 ---RRK-Lqlyne----------------------------------------------------------------aqr 456 
WP_096300121 369 ------wIhlystdeeqqtaldnrlfltleqearsrtglgqdatledILlndeashqlrklagfqesdtllshharlrrs 442 
WP_106719945 698 ---YRE-Ikli----------------------------------nikLnrked------------------------de 715 
WP_066850818 748 --PYS-----KREFGVPS------------NLHVIGTMNTADRSIAQIDTALRRRFKFEEIAPDPSll---------tTa 799 
WP_011274428 288 lyNSSk---yNHEITIGK------------NVRFVGTVNIDESTYHFSNKVLDRADLITLEVMPFK------------Ql 340 
WP_083825933 443 ynLLKk---yKAQVEIPD------------NIRFVGTVNKDETTKSLSPKVIDRSFVIEVKEydenlvskfselekenyq 507 
WP_051120440 126 fyNSEr---yPATVTIGT------------NIMFVGTVNLDESTHQFSDKVLDRANLISLKLLPFT------------Em 178 
WP_045473360 424 -kSIRgvsnnTSKVLISP------------ALRFIATINNDHTTLSLSPRVLDRTSIVELSLEPRTtldrakldleekQi 490 
WP_071479613 462 raRRKd---aEIELEIPTpdgqiprifpgyNLLFAGTMNEDESTQSLSDKVVDRANVIRFAAPRQI------------Vr 526 
WP_083957698 465 anERKd---aEIELEIPNmerppr-ifpgyNLLFAGTMNEDESTQSLSDKVVDRANILRFSAPKKI------------Kg 528 
WP_087455678 457 lyNSKe---yPPEVTIGD------------NVMFVGTVNIDESTYHFSDKVLDRANVITLEVLPFQ------------Ql 509 
WP_096300121 443 vsTLIr---iPPGFRYPS------------NVWIIGAINVDETTHYLSPKILDRVHVLRFLNPVLV------------Dw 495 
WP_106719945 716 eiEYKal-ehGNTLKVPA------------NVWFIGTANRDESTFVISDKVYDRAHTMNFTKRAPKv----------rNy 772 
WP_066850818 800 d-----------------------------------gISlRQVLTVINQRI-EYlidRDHRI--GHA 828 
WP_011274428 341 veitniekikttegisf--eqeyiksffknsktidldNDtIDFLQEMHNTL-LN---INNQSgiGPR 401 
WP_083825933 508 krlylkesdfkmeskdildeikeeleeiklifkkmrvylnnrfdnqvkqilgndyidrddlldyiis 574 
WP_051120440 179 vesnqdkidniptpais---dkeyrsfknnnsklkleRNeLEFLWELHNEI-HE---VNKNIgiGWR 238 
WP_045473360 491 m-----------------------------------------sIEELDALL-Ky---KNAMF--SLR 510 
WP_071479613 527 gaaqgdrpatealkr------svwagwsrprrdqqerDVaQAKIADMVDLM-KE---LGRPF--GHR 581 
WP_083957698 529 gqaegtveptlalsq------qaweswgrssasvdgdRRvTNRIEQMVDLM-RD---FKRPF--GHR 583 
WP_087455678 510 levrevsskrndrewt----lkdfrniktgsdalmltSEeTAFFWELHQLL-EQt--RGQGF--GPR 567 
WP_096300121 496 qeeenslvdfdldttlpvrmratdlgvrasyppfdrsQSeVAWLAHLSSKFlDP---LGVEF--GLR 557 
WP_106719945 773 qnpiarkyydyeii---------ndlfmdakaagdfdAEqNEIIKKVEVLL-AP---FNISF--GNR 824 
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap