Conserved Protein Domain Family
TMEM117

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pfam15113: TMEM117 
TMEM117 protein family
The function of this family of transmembrane proteins has not, as yet, been determined. Members of this family are as yet uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 181 and 504 amino acids in length.
Statistics
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PSSM-Id: 434469
Aligned: 8 rows
Threshold Bit Score: 648.325
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_028913802   4 DFRYYFQHPWSRLVVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPrEGGWRLLKVLLWLLAILIGLIAG 83 
XP_001626351   2 NSRYYFQHPYLRLFICYFIIFCNFLIYAEDPVAHSLSQCTIPVIGNVFAFVVNNYP-PNGWAALKFFMWFFGMITGMLIG 80 
XP_001623999   1 -WRYYFRHPWSRIITSYLVVFLNFFIFAEDPVSHSYEECTIDYIGDVYTFLFIRWP-SGSFVLVKLGTWLFAISLGLLIG 78 
EDO31898       2 GFKYWLRHPYLRLMTSYLVVFCNFLIFAEDPVSHSYTDCVIDIIGNIYAFILARYPpHGGYVALKIFMFVLAFITGMVIG 81 
XP_002434058 202 DFRYFLQHPYARLFVSYFVIFCNFLVFAEDPISHSRTESEIPVFGNVFSFMCTKYPpEWGWRCLKVLLWLVALFWGLVCG 281
EEN64576       4 DFRYYFQHPYARLFVAYLVVFCNFLMFAEDPVSHGITPANVIVVGNIYSFIVDKYP-GGAWNVFKVFMWLLAIVVGMILG 82 
CAG08648       6 RFRYYFQHPWSRLIVAYLVTFFNFLIFAEDPVSHSQTEARMIVVGNCFSFLFNKYP-GLGWNVLKVVCWILAMITGLLAG 84 
NP_001094703   4 DFRYYFQHPWSRMIVAYLVIFFNFLIFAEDPVSHSQTEANVIVVGNCFSFVTNKYPrGVGWRLLKVLLWLLAILIGLIAG 83 
XP_028913802  84 KFLFHQRLFGQVLRLKMFRED-HGSWMTMFFSTILFLFIFSHIYNMILLMEG-NMGAYIITDYMGIRNESFMKVAAVGTW 161
XP_001626351  81 KFFVHKLLLRKWMKLSMFQED-KGSWMVMFLTTIVLLFVFSLIFNGLVSLGG-SIAAYKVTSFLGFTNKTFMKAAAMGTW 158
XP_001623999  79 KFLLHKWLFCQKLKLKIFTEDgQGSWMVMFLSCFFFLFVFSYAYNGFLMLEGkYMDTLHASSRMGMQNQTFMKFAAMGTW 158
EDO31898      82 KYFVHKFLLCRVFRLKMFSEEgQGSWMIMFLMVLVFTFVWSFCFNEFLLLGRpDYLRYKVSSNMGIENQTFMKFAAIGTW 161
XP_002434058 282 KYIIHHFLLRNLCRLKMFREE-QGTWMIMLLTMVIFVYMFSLVYNFFLMSAYpEPELFRINALMGITNANFMKFAACGTW 360
EEN64576      83 KFLVHKLFFGRLLRLKMFHRD-GGSWFIMFLTTLMSLFIFSNIYNGIILAAG-LNYDLQISDVMGLRNSSFMKAAALGTW 160
CAG08648      85 KFIFHRQLFGRYLRLKMFRED-HGSWMTMFFSTILFLFIFSHIYNLFLLMAG-NMKPHMVTDYMGIRNESFMKIAAVGTW 162
NP_001094703  84 KFLFHRRLFGQLLRLKMFRED-HGSWMTMFFSTILFLFIFSHIYNTILLMDG-TMGAYIITDYMGIRNESFMKLAAVGTW 161
XP_028913802 162 MGDFFTAWMVTDMMLQDKPYPDWGKSARAFWKK-GNIRIILFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRA 240
XP_001626351 159 MGDFVTAWMVTDMMLQDKLYPHWNKRLRKWWQA-GWNRIVMFWIVLIVATVIVATAITTDYLDWDRYNRWIVSSNELSRA 237
XP_001623999 159 LGDFFTAWMVTDMMLQGLKYDNWAKGVRVFWNK-GLNRVYVFWFVALAMTIVVSTAISTDYLDWDRISRNFMPTNELSRA 237
EDO31898     162 FGDFITAWMVTDMMLQEDQYEWWSRGLRRWWRR-GLNRVYAFWGVAFTMTVIVCTAITTDYLDWDRISDDFMPTNELSRA 240
XP_002434058 361 LGDFLTAWMVTDMMLQDQLYPSWARSLRAFWQShGRTRIIVFWSGTVILSTVVISLIVSDYISWDYLNREFVATTELSRA 440
EEN64576     161 MGDFVTAWMVTDMMLQDTLYETWARPVRHWWRQ-GWHRIILFWAVLLSLTGVVVMVITTDYIDWDYLNRGFLPTNELSRA 239
CAG08648     163 MGDFVTAWMVTDMMLQDQNYPDWAGAARRFWKR-GNNRIVLFWTVLISLTSVVVLVISTDWISWDNLNRGFLPSDEVSRA 241
NP_001094703 162 MGDFVTAWMVTDMMLQDKPYPDWGKSARAFWKK-GNVRIILFWTVLFTLTSVVVLVITTDWISWDKLNRGFLPSDEVSRA 240
XP_028913802 241 FLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFK-------LPffQKIFKEEYRIHITGKWFNYGVIFLVLI 313
XP_001626351 238 FLAAIILVFDLCIVMQDWDFPMFRGNMDIKLPGVDTASVRIR-------LP--RCLRKEKWYIHITGKWFNYGIIMLVII 308
XP_001623999 238 FLASFILVMDLTIVMQDWEFPHFAGALDIKLPGANTDSIDFS-------LP--GCFGGERLDVYITGKWFNYGIIFIVMI 308
EDO31898     241 FLASFILVMDLMIVMQDWEFPLFAGGMDIKLPGINTGDINFK-------MP--------GGDVHITGKWFNYGIIFIVMI 305
XP_002434058 441 FLASFILVMDLLIVMQDWDFPHFVCDLDIKLPGMHAASFKYRmfqkyvhLP--------EIVFHITGKWFNYGIIIIVML 512
EEN64576     240 FLASFILVMDLLIVMQDWDFPHFMGSLDIKLPGINTTHIRLH-------IP--KCLRKDEWTIHVTGKWFNYGIIMLVII 310
CAG08648     242 FLASFILVFDLLIVMQDWEFPHFMGDLDLNLPGMSTTHVKVK-------LPvcKSIFKEEYHIHITGKWFNYGIIFLVLI 314
NP_001094703 241 FLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFK-------IPffQKIFKEEYHIHITGKWFNYGIIFLVLI 313
XP_028913802 314 LDLNMWKNQIFYKPHEYGQYIGPGQKIYTVEDSESLKD--LNRTKLSWEWRSNNTNPLTNRTYAEGDMFLHSRFTGTSLD 391
XP_001626351 309 LDLNMWKNQIFYNPYEFGQYTLPSHHICYIEDRAFLAT--ANETMVSYDWRATHINPATNLSYASADRKMNAKYFGYSLG 386
XP_001623999 309 LDLNMWKNQIFYEPLTYGQYTDPLGYIYTIADKQYLRW--ANDSMKTYEWRWNHVNPKTNRTYGSDDHKMNTRYHGYTLG 386
EDO31898     306 LDLNMWKNQIFYEPFIYGQYTDPDGYIYTVMDRAWLRN--ATRETLSYAWRWNHTNPLTNVTYGLADHRMNSRYHGYPLS 383
XP_002434058 513 LDLNMWKNQIFYYPPDYGQYTGTDNKVRTVASYAVLAT--GNRTLWTLENRQNVLNPRTNESLMEDDILMNSRYLGYPLS 590
EEN64576     311 LDLNMWKNQIFYKPFDYGQYVGPDDSIHFVRDIDTLQGdlFNRTTLTYDWRANHTDPATNLTYLERDLHMHSKYIGFTLG 390
CAG08648     315 LDLNMWKNQIFYRPYEYGQYVGPGDKIYTVEEPETLVN--FNRSTLTYDWRSTNIDPETNRSYVERDMFLHSRYTGASLD 392
NP_001094703 314 LDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKD--LNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIGASLD 391
XP_028913802 392 VKCLAFVPSLIAFVWFGFFIWFFGR 416
XP_001626351 387 VKSTAFIPSIAVFILFGLLIWFYGR 411
XP_001623999 387 LKSMAFVPSLLAFCLFGYLVWLFGR 411
EDO31898     384 VKGIAFGPSIAAFVAFGYLA---KR 405
XP_002434058 591 VKGLAFLPSLLGFSMFGVLTYLYGR 615
EEN64576     391 VKGIAFVPGLMAFVTFGVLIWWYGR 415
CAG08648     393 VKCLAFIPSLAAFVLFGFFIWLFGR 417
NP_001094703 392 VKCLAFVPSLIAFVWFGFFIWFFGR 416
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