Conserved Protein Domain Family
Miff

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pfam05644: Miff 
Mitochondrial and peroxisomal fission factor Mff
This protein has a role in mitochondrial and peroxisomal fission.
Statistics
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PSSM-Id: 461701
Aligned: 20 rows
Threshold Bit Score: 244.739
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
OCA35587      13 MAEINRMQYEIEYTEGISQRMRVPEKLKVAPSNS--GVDPKVQP-D----MSL----PGVMMEVPERIVVAGHNEESPFS 81 
XP_011484419  12 VTEISRIHYDLEYMEGISQRMRIPETLKVGPESS--AGRMQAQE-P----PPP----HSTLMQVPERIVVAGDDGDLTFP 80 
XP_005476071  13 VAEMNRIHFELEYTEGISQRMRIPETLKVAPESQ--TGSMPLQQ-P----LPT----HTALMQVPERIVVAGDDEDPRFA 81 
XP_005802419  12 VAEINRIHYELEYTEGISQRMRIPETLKVAPESR--SGAALLQP-P----LPV----HTTLMQVPERIVVASDNGESRFV 80 
1_pfamImport   1 VAEMDRIHFELEYTVGISQRMRIPETLKVASENH--PGSLSLQH-P----LPL----HTTMMQVPERIIVAGDDGDLQFS 69 
XP_005171224  12 MAEVNRIHYELEYTEGISQQMRIPERLKIASGSS--EEPPGLLNaS-----------HSTMMHVPERIVIAGDDNDARFG 78 
XP_002412416  12 FSGDYDAFYDPEFTAEISNKMRVPQKISVVDQ----DEYKLIEDmG----PNKlhfnDAAYMHVPDRILVRGGNQHIEGR 83 
EDW35932      14 L--DDDLYNEAKFAHEINDKMRVPKRIKATGEYS--DEDLLLSNqNgnqfISSwnyhDKIDMNVPDRIVVLGHNQHLETR 89 
XP_001866796  12 NYEDDALYQNAAFTHDISEQMRVPKRIRATGGSYfdDEPELLSNgNg--eINSwnyhNKIEMNVPDRIVVLGQDQHLGTK 89 
XP_321339     12 NYDDDAMFQNAAFTHDISEQMRVPKRIRATGDYY--DDQDLLPNgNg--eINSwnyhNKIDMTVPDRIVVLGQDQHLGTK 87  Anopheles gambi...
OCA35587      82 RP-SDLDFIPGT-N-IE--T-LALKTPPRVLTLSERPLDFLDLEgsTPATPHNEE-VRSSVHLKKERLASEN--PLRQNG 152
XP_011484419  81 RP-RDLDLIQSV-P-PA--DlLNMKAPPNVLTLTEQPLDSLETDqtANAQRNSSN--ATSLHARARRERSDNv-SSRHGN 152
XP_005476071  82 CP-RDLDLIQSI-P-PA--DlLNMKAPPRVLTLTEQPLDSLETDqtVNSQRNPSQaANFHGRPRRERSASENv-SGRHSS 155
XP_005802419  81 QP-RDLDLIQSV-P-SV--DlLNMKAPPRVLTLTEQPLDSLEMDqaANSQSNPSQtASYSTRSRRERSASENi-PGRHGS 154
1_pfamImport  70 HP-RDLDLIQSL-P-PM--DlLSMKAPPRILTLSEQPLDSLETEqtATSQSNPIHaAHFHARPRRERSASENl-SGRHSN 143
XP_005171224  79 RP-RDLDLIQST-P-LE--T-VELKTPPRVLTLNDQPLDFLEPEpaANSTAQPREeMKSHFRSRRERCRSENs-TMRRNG 151
XP_002412416  84 DPlPETRLEQSLvGsAE--EtILLSTPPRTLTLDMHAYPAVDME------DENAE-NRSALKFRRKTTLSKL-----HNG 149
EDW35932      90 SApREIQLENSIlPkNPsaSyARVQTPPRVITLTDHHF--------PSASEESSP-IRANGHHLYGQDQDYDedEQGNAT 160
XP_001866796  90 SApREIMLENSIlPkDP--GfVRVSTPPRVITLSEHHF--------PSASDELED--EDRDLTMRGDGGDDDdyEPRSLD 157
XP_321339     88 SApREIMLENSIlPkDP--GfVRVSTPPRVITLSEHHF--------PSASDEPEE--------NAKDNHQEDnyGPASLE 149 Anopheles gambi...
OCA35587     153 QLVRHDSI-------------------------PTPSAPAGRLCPAPSPPAV-GADLFSARGILSLIQTSTRRAYQQVLD 206
XP_011484419 153 QISRGDVSv-----------------------tSSPHAPPLRLCPPLYSPEDaNINLFTAAGLLSYIQSTTRRAYQQVLE 209
XP_005476071 156 QISRGDVSv-----------------------tPSPSAPPVRLCPPLCSPEDvNINLFTAAGLLSYIQSTTRRAYQQVLE 212
XP_005802419 155 HCSRGDVRffqpsp--------------casvtPSPSAPPVRLCPPLCSPEDaNINLYTAAGFLSYVQSTTRRAYQQVLE 220
1_pfamImport 144 QIVRGDASyadftpeknlislpflptyfsdsvtPSPSAPPVRLCPPLCSPEDaNIHLFTTAGFLSYVKSTTRRAYQQVLE 223
XP_005171224 152 QINKHDFAs------------------------PSPSRAPVRVCPPLISPED-SQNLNSASGVLNYIKSTTRRAYQQVLE 206
XP_002412416 150 DITFVNs----------------------------------------------GVNVHHSQNDFNFVACVSEIGATHNSH 183
EDW35932     161 QYVRANg----------------------------------------------TARMGFHTNDANSVESDSQ-------- 186
XP_001866796 158 SMLGAE----------------------------------------------------AVGGGGGSVGKGGQRQRQQQQQ 185
XP_321339    150 SIEDPN----------------------------------------------------------SSNAYFSRPSL----- 166 Anopheles gambi...
OCA35587     207 VLDENRR-------PILRGGSSNSAPVTHHD---------NPRSAMSTLD-ATLDATP------DDLALADAASLRRQII 263
XP_011484419 210 VLDDGH---------R-----------------------------RTHLD-STLDINP------DESGLVDASSLRRQIV 244
XP_005476071 213 VLDDSHR-------R-------------------------------THLD-LALDLNP------DESGLVDASSLRRQIV 247
XP_005802419 221 ILDDSH---------R-----------------------------RTHLD-LALDMNP------DESGLVDASSLRRQIV 255
1_pfamImport 224 VLDESHR-------RVMNGARLCGHYAPVHQ-----------SFLGTHLD-LALDINP------DESGLVDASSLRRQIV 278
XP_005171224 207 VLDDSQR-------G---------------------------RASLVTFD-ASVENTP------DDAGLTDAASLRRQII 245
XP_002412416 184 RIEPWTPvqhpfkgS-----------------------------PRPSFC-RSAPATPpgipgsDD----ELGMLKRQIR 229
EDW35932     187 ---------------LTTGSASKRSQLNQQQhnnldasmlAQREGTPMGE-----LTP------HE----EILYLRRQLA 236
XP_001866796 186 RFGAGR---------GVNGELQRKTAFAKHNssel-vlgrSFREETPTFGgSVENLTP------AE----EMTHMRRTVA 245
XP_321339    167 ---------------AHGREPSKRSAFSKYNnelt--ltrSMREETPTFGgSVENLTP------SE----ELTHLRRQVA 219 Anopheles gambi...
OCA35587     264 KLNRRLLLLEEENKERVKHEMTMYSIIIIFGLLNSWLWFRR 304
XP_011484419 245 KLNRRLQLLEEENKERSKREMILYSATVAFWLINTWIWLRR 285
XP_005476071 248 KLNRRLQLLEEENKERSKREVILYSATVAFWLINTWIWFRR 288
XP_005802419 256 KLNRRLQLLEEENKERSKREVALYSTTVAFWLINLWIWLRR 296
1_pfamImport 279 KLNRRLQLLEEENKERSKREVILYSATLAFWVINTWIWLRR 319
XP_005171224 246 KLNRRLQLLEHENKERAKREMVMYSLTVAFWLVNSWIWLRR 286
XP_002412416 230 NVSRRLVAVEQENQQRQQREVVLYSVGLLYFLLKGLFWLNR 270
EDW35932     237 KLNRRVLNIEINNEQRMQREKIVYCLGLAYFVLKTIFWLNR 277
XP_001866796 246 KINRRLLAVEIDNAQRQQREKIIYCVGLAYLLLKTFMWLSR 286
XP_321339    220 KINRRLLAVEIDSVQRQQREKIIYCVGMAYFLFKTFMWLSR 260 Anopheles gambiae str. PEST
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