Conserved Protein Domain Family
Vps52

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pfam04129: Vps52 
Vps52 / Sac2 family
Vps52 complexes with Vps53 and Vps54 to form a multi- subunit complex involved in regulating membrane trafficking events.
Statistics
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PSSM-Id: 282044
Aligned: 5 rows
Threshold Bit Score: 636.817
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P39904  47 NKDQSPFAKLKs--LQETHSNNEAAINIIIPQLIDYLTEFTNRLSNYTQDLDFIKKKSNELQSLLEYNSTKLAHISPMVN 124 Saccharomyces cerevis...
Q9UST3   1 MQRASTQDVYD---GSGDDLNKLDSLKSVLNDVLSSLERFQVDLDVATSDIYKVSERSNKIQVNLNNLKAVESALGAEID 77  Schizosaccharomyces p...
Q94KD3  86 veldsieDYIKesdNLVSLHDQIRDCDSILSQMETLLSGFQEEIGSISSDIKILQEKSMDMGLRLKNRRVAESKLAKFVE 165 thale cress
Q9VMQ8  42 VENKSIEDYIAesqNIANLHNQINDCDDVLERMENMLMSFQSVLNNISTEITQLQRKSVSMSLQLTNRQSVKAQLSQFIE 121 fruit fly
O55166  94 IEQKSIRDYIQeseNIASLHNQITACDAVLERMEQMLGAFQSDLSSISCEIRTLQEQSGAMNIRLRNRQAVRGKLGELVD 173 Norway rat
P39904 125 DLMIPPELIDDIIKGKINEswqdniTFIADKEEIYNKYRSNNLDQDnkdaeNSAMLAPKDFDklcQLLDILKNVILERSK 204 Saccharomyces cerevis...
Q9UST3  78 GAILPPDLIKTISTGDMDH------PSWNSALEKLTSFLEGGEDDSslgnmFNSLQINKDQK---KLVDKLRDKAIERIR 148 Schizosaccharomyces p...
Q94KD3 166 DIIVPPKMIDVIVDGEVNE------EYMKTLEILSKKLKFVEADQA-----VKSSKALKDVE---PELEKLRQKAISKVY 231 thale cress
Q9VMQ8 122 DMAVSEEMINIIMETPVTE------RDFSTQLNVLNHKLSLVKELS-----FKESKSTSDVS---DVLQKLRLKAMAKIR 187 fruit fly
O55166 174 GLVVPSALVTAILEAPVTE------PRFLEQLQELDAKAAAVREQE-----ARGTAACADVR---GVLDRLRVKAVTKIR 239 Norway rat
P39904 205 RLIISKIKTLRSHNpVPSQRIQN-KLLKVQKIFPFIRDNNLSLALELRQAYCYTMKWYYREYFSRYIRSLTILQFQQIDS 283 Saccharomyces cerevis...
Q9UST3 149 NYIVVTIKMFRQAF-VDVFPIRKhRLIANKNYYLFLFKFNRKLALELQRAYINTMNWFYLYHFEQYSRFLDKVHVLKGET 227 Schizosaccharomyces p...
Q94KD3 232 DFIVQKLIALRKPK-TNIQILQQsVLLKYKYIISFLKEHGKEVFMDVRAAYIDTMNKVLSAHFRAYIQALEKLQLDIATA 310 thale cress
Q9VMQ8 188 SYLLEQIYKFRKPM-TNYQIPQN-AMLKHKFFFEFILSNERHVAQEICSEYIDTMGKIYYSYFKSYSTRLTSLKFEESCT 265 fruit fly
O55166 240 EFILQKIYSFRKPM-TNYQIPQT-ALLKYRFFYQFLLGNERATAKEVRDEYVETLSKIYLSYYRSYVGRLMKVQYEEVAE 317 Norway rat
P39904 284 QfalgnGLSTTSVsgfnnspSLFFSnylttsasnafynkLPVTDEKIDKYFQIKKRLNILT--QEDNTVMVSQIAENNtt 361 Saccharomyces cerevis...
Q9UST3 228 I-----RVEEDRK-------GLFNLs-------------KGAQQSYGNQMLSVNLRPQDFDmnSVLTASTMHHIESSP-- 280 Schizosaccharomyces p...
Q94KD3 311 Ydl--iGVETRTT-------GLFSR--------------AREPLKNRSAVFALGDRIKIIK--DIDQPALIPHIAEASsl 365 thale cress
Q9VMQ8 266 Kdd-lmGIEDNAS-------KGLFS--------------KTTSLKHKSTIFTIGKRGDILNq-QLEAPIIVPHAQLKNr- 321 fruit fly
O55166 318 Kdd-lmGVEDTAK-------KGFFS--------------K-PSLRSRNTIFTLGTRGAVISpaELEAPILVPHTAQRGeq 374 Norway rat
P39904 362 kNYIEIGFKNLNLAILDNCTVEYHFLKDFFAMNGDNFEEInglLEQIFQPTFDEATTYTQQLIQYNYDIFGVLISIRVAN 441 Saccharomyces cerevis...
Q9UST3 281 -QYIERVYCSWELVLTEHVSSEYAFLLEYFNLSKDQQATV---FAAIFEKTLHFSRKYITGLISSSIDCIGILKSIRFTQ 356 Schizosaccharomyces p...
Q94KD3 366 kYPYEVLFRSLHKLLMDTATSEYMFCDDFFGE-----ESI---FYEIFAGPFSVIDEHFNPVLSNCFDAIGLMLMIRIIH 437 thale cress
Q9VMQ8 322 -YTAEALFRSEQYALVDNACREYLFVTEFFMVRGTQAQDL---FNQIMGKTLTLMIKNLETSIHDCFDTIAMFLCIHLIF 397 fruit fly
O55166 375 rYPFEALFRSQHYALLDNSCREYLFICEFFVVSGPAAHDL---FHAVMGRTLSMTLKHLESYLADCYDAIAVFLCIHIVL 451 Norway rat
P39904 442 QLQFESERRGIPsMFDSFLNGQLIQLWPRFQQLVDFQCESLRKAAITTNVAkyagnsstsnssPLTSPHELTVQFGKFLS 521 Saccharomyces cerevis...
Q9UST3 357 KLALQAQTNIVP-VIEPHYNSMILFLWPRFQAVMDMHCESLRKTNLSVKPEe-----------ITSRPHPLSQRVAELLY 424 Schizosaccharomyces p...
Q94KD3 438 HHQLIMSRRRIP-CLDSYLDKVNISLWPRFKMVFDSHLSSLRDANIKTLWE------------DDVHPHYVMRRYAEFTA 504 thale cress
Q9VMQ8 398 RYQLMCHKRCVP-ALDKYWDSLQAVIWPRFELVFRLNIQSIHDCDPTKFN-------------KELGPHYITRRYAEFSA 463 fruit fly
O55166 452 RFRNIAAKRDVP-ALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGG------------LDTRPHYITRRYAEFSS 518 Norway rat
P39904 522 SFLTLAITHKQSIderSEPLYNSIIRLRNDFETVMTKCSKKTKSPERFLATNYMYLYNNLQQLHLHLNINDSDAQNYNFD 601 Saccharomyces cerevis...
Q9UST3 425 SLSMLSVNVVEAEp--VARSASRLAQDYVSMLQNLCKTVNDKRRQSRFLSNNYTLISTVLSGVSGNLAIEQKTYFEKLNE 502 Schizosaccharomyces p...
Q94KD3 505 SFIHLNVEYGDGQ---LDINLERLRMAVDGLILKLAKLFPRPKQQIVFLINNYDMTIAVLKEAGPEGGKIQMHFEEMLKS 581 thale cress
Q9VMQ8 464 AIVGISEHFPNEL---VSRLLLELQNEVECFILRMAAIFPTRKDQLIYLINNYDLVLGVLMEHTRDNSKEAEAFREQLNS 540 fruit fly
O55166 519 ALVSINQTIPNER---TLQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNA 595 Norway rat
P39904 602 SAENVG 607 Saccharomyces cerevisiae S288C
Q9UST3 503 NLTNFQ 508 Schizosaccharomyces pombe 972h-
Q94KD3 582 NTSLFV 587 thale cress
Q9VMQ8 541 RSAEYV 546 fruit fly
O55166 596 RTQEFI 601 Norway rat
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