3JD5


Conserved Protein Domain Family
DAP3

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pfam10236: DAP3 
Mitochondrial ribosomal death-associated protein 3
This is a family of conserved proteins which were originally described as death-associated-protein-3 (DAP-3). The proteins carry a P-loop DNA-binding motif, and induce apoptosis. DAP3 has been shown to be a pro-apoptotic factor in the mitochondrial matrix and to be crucial for mitochondrial biogenesis and so has also been designated as MRP-S29 (mitochondrial ribosomal protein subunit 29).
Statistics
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PSSM-Id: 431160
Aligned: 24 rows
Threshold Bit Score: 284.192
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3JD5_g        98 LMVRKPALELLHYLKNT-NFAHPAVRYVLYGEKGTGKTLSLCHIIHFCAKQ-DWLILHIPDAHLWVKNCRDLLQSTy-NK 174 cattle
O59677       170 LLHRKITTELVNVLQRSkDQGTKDGRFLLDGAPGSGRSIALIQAELFALSQpNFIVLPVHNCEGWVNSTSSYGYDE--QL 247 Schizosaccharom...
NP_001092207  98 VMVRPAALELISYLKKA-DYNKPPLRYVLYGQTGSGKSISLCHTLHYCYTQ-GWLILHVPDAHLWVKNCKEMLPSTy-NP 174
CAG11844      37 iMVRSPALEVISYLKKT-DNTRPAVRYLFYGLKGSGKTMSLCHVVHFCYTQ-GWLVLHIPDAHIWVKNCKELLPSSy-NR 113
Q9W253        93 LMVRNPALELLQYIKDG-DLTKPVVRYVLYGENGTGKTLTMAHVLHYGALN-DFLLVHVPWAPNWMKRPKEASNAAg-QE 169 fruit fly
Q6FQ32       106 SLVREST---TKKLIDE-LKNGTSKKLIITGEPGVGKSVLLSQVHAYGLES-NMLLINISYPESFLNGRNDFMFDE--SL 178 [Candida] glabrata
Q01163       124 CLVREDA---TNSFLKK-LVSHPVKKFIITGEPGVGKTVLLSQAHAYAVDS-KQIIINISYPELFLNGRNDFSYDD--DL 196 Saccharomyces c...
EDO14441     116 SLVREGT---TKKFLDL-LKKSANKKFIVTGEPGVGKTVLLSQVHAFATEA-KSITVNISYPELFLNGRNDFFYDE--NS 188
Q755C9       113 CYTREATGQLLERLSGT-----EHQRVILTGQPGVGKSTLLAQAQVAAFEK-GSVIINISHPELFLNGRNDFRHDTtgEQ 186 Eremothecium go...
Q6CWQ9       111 SLVRDST---TRKLYEA-LRKSENKKLVLTGEPGVGKSTLLAQLHAHALEN-KGLVLTVSNSELLTNGRNDFFLDE---- 181 Kluyveromyces l...
3JD5_g       175 QRFDQPLEASIWLKNFKTANE-RFLSQIK--VQDKYVWNk-----------RESTEKGsPLAEVVEQGIMRVRNATDAVG 240 cattle
O59677       248 KLWVQPDLIKGFLTSVMKTNS-DKLKKLK--TFESHELLq-----------NECIPAGtDLLSFLHKLIASSNAPK-SLE 312 Schizosaccharom...
NP_001092207 175 LRFDQPVQATQWLKDFKITNE-HFLSKIK--TTRRYVWTk-----------RESTEEGrTLGELIDQGVNRMKSSSDVVG 240
CAG11844     114 ARFDQPLQANEWLRNFKTTNE-KFLSTIK--TKHRYVWTk-----------RESTNEGsTLGELVDQGINRMKSSSDVVA 179
Q9W253       170 GMIDLPFDAAAWLVHFKTQNG-PLLQRLQlkTSKEYVWSk-----------RESTPAGsSLIELVEHGIARIKYASETTA 237 fruit fly
Q6FQ32       179 KLYTQPMYTKELIRKILKANKpEVLEKIP--LTKNYKFTganskdsghtatIQLKEGQhTLSNLLSVKANPQNVGI-QFQ 255 [Candida] glabrata
Q01163       197 KLFIQPMYLKKLIRKILKANDpALLKSIE--LSKDYKFSnanpknasvkpfVTLNKTKnTVLDLLSVMTHPHNRGK-LMK 273 Saccharomyces c...
EDO14441     189 KLYVQPMYLKSFIRKILKGNDkSVLKSIT--LANDYKFPnndskd-vnrkhLTLFGGKnTLYDLLSVKTVSRSRGE-LFQ 264
Q755C9       187 EQYTQPMYLKKLLTKILKSNKkSVLSSVA--LTQEYKFPvadtresaskrvTRLVPGKtPLYGLLSMKTTPAARGM-LFQ 263 Eremothecium go...
Q6CWQ9       182 DRYIQPMYIKNLLTKFVKSNKkELLQSIK--LSKDYKLVhsggkdlsvkrnVNLSAGKsTLYDLLSVKAPSRHRGA-VFD 258 Kluyveromyces l...
3JD5_g       241 IVLKELKRQSSl-----gVFRLLVAVDGVNALWGR--TTLKREDKSPITPEELALIYNLRKM--VKNDWQGGAIvltVSQ 311 cattle
O59677       313 IFLQELNNNTKsn----sNMKVLLVIDNISILSVV--TKYKDKKNNFLPPKDFYFINLLFKYisGSLTFNRGTV---LAA 383 Schizosaccharom...
NP_001092207 241 AVLRELRLQAGattegeeVFKLAVAVDGVNALWGN--TTLKKEDRTMCEPEELTLIHNLRKM--MKTDWRGGAIltaLSQ 316
CAG11844     180 AVMKELRLQSGqp---esNFRLAVAVDGVNALWGR--STIKKEDKSFVDPEELTLVYNLRKL--MRNDWAGGAIittLSQ 252
Q9W253       238 ALIAELKQLSTa-----gQCKVMVAIDGFNAFFHPv-TRIFSDNKQLVTPDRVTLTQPFLDI--TNYDWTNGVCilsVDK 309 fruit fly
Q6FQ32       256 AVMEELLAQEK--------VPVLFTIDNFSRFLTKayTDYRNVKNQQIYSLQFQLGKTIMDIisGDSRFKNKRSafvAAI 327 [Candida] glabrata
Q01163       274 AIIDELSVQSK--------VPIMFTVDNFSKVLTTaySAYRNTENKQIYSLDLQMGKLMMDIisGETKFANGESstiLAI 345 Saccharomyces c...
EDO14441     265 SIMQELKSQSK--------VPVYFTIDNFSRILVTsdCAYKNVNNKNIRSLDLQIVKTIMDFvsGDSKFKNKNSaivMAT 336
Q755C9       264 AVIDELVAQSA--------VPVYLTVDNFSRILSEplSAYKDTSCRSIHVLKLQLGRIIMNFvsGATKLNHKDSrvvLAT 335 Eremothecium go...
Q6CWQ9       259 AFIKELTNQTD--------HPVYFTVDNFSHLLTTpfTAYKDTSNKNIHILKFQVGQSIFDLvsGDLQFAAKDScvvLAT 330 Kluyveromyces l...
3JD5_g       312 TGSLFKPRKAYLPQELLGKEGFdtlDPFI-------------------PILVSNYNPKEFEGCIQYYLENNWLQHEk--- 369 cattle
O59677       384 TSSQPRVSTPSLDIALGVAHR----NPYKssdetil-----dslqsvhILNMEPYTLDESRRMMEYLVSSNVCLEK---- 450 Schizosaccharom...
NP_001092207 317 TGSLFKPRSAYLPSELLGEEGFdemEPFV-------------------PVCVSGYNEKEFGSCYLYYLDRNWLQHPr--- 374
CAG11844     253 TGSLYTSRAEYLPQELLGEMGFdnmDPFV-------------------PVSVPNYSEKEFESCYLYYTDRHWLQHPq--- 310
Q9W253       310 IAMTEGHMDSYMPRYLLGKEGFehlDPFV-------------------PIHVENYTDKEFHSYISYYLDRHWIN------ 364 fruit fly
Q6FQ32       328 SGVDRTNK--TLPVGLGKLEE----DPYVtryhyekkfadllkrgrveEFEVPKWSKEEIRTLINFYRDSGIISGKelds 401 [Candida] glabrata
Q01163       346 SGVDRTNK--TLPVALGKIPV----DPYVtryhyepkfvellqkgnvtEFEVPKLNKQEVNELIDYYKQSNVLLDKditg 419 Saccharomyces c...
EDO14441     337 SGDDRTNR--TLPIALGKAQH----DEYIprkqydpefaeilkkgkveEFQVPKLTKEEVKELMSFYLESDIVLKKdkds 410
Q755C9       336 SGVDRETK--TLPTGLGQTPH----DPYAakynydavlaemmlkggvkEFRVEPLSKPEVAELVDFYAKAGILSEKdqen 409 Eremothecium go...
Q6CWQ9       331 SGLDRTNR--TLSIGLQKLPH----DPYLtryhyeqilaekllkgkvqEFEVTKLNKDEVAKLMEFYQKAGIVLDKdlqn 404 Kluyveromyces l...
3JD5_g       370 -AHTEEGKKELLFLsNrnpglleRL 393 cattle
O59677       451 -VDNYLQNHVLS---GgnprkffDA 471 Schizosaccharomyces pombe 972h-
NP_001092207 375 -SRSEEGKKELIFLsNrnpsileRL 398
CAG11844     311 -SLTEDGKKELIFLsNrnpsvfeRL 334
Q9W253       365 -KTPQGFEEQLKFMsNknpyslmQL 388 fruit fly
Q6FQ32       402 kTPEQYTDEKYFVSgNgnprellKS 426 [Candida] glabrata
Q01163       420 kKWENLIDEKYFLSgNgnprellKS 444 Saccharomyces cerevisiae S288C
EDO14441     411 kSLDQLVDEKYFLSgNgnpreliKS 435
Q755C9       410 rREGRLVDEKYLLSgNgnlrellKS 434 Eremothecium gossypii
Q6CWQ9       405 kTFEQLTEEKYFLSgNgnprellKS 429 Kluyveromyces lactis
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