7KZP


Conserved Protein Domain Family
Fanconi_C

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pfam02106: Fanconi_C 
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Fanconi anaemia group C protein
Statistics
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PSSM-Id: 426603
Aligned: 16 rows
Threshold Bit Score: 734.145
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7KZP_C        35 CDYQFWMQKLSVWDQASTLETQQDTCLHVAQFQEFLRKMYEALKEMDSNT-VIERFPTIGQLLAKACWNPFILAYDESQK 113
XP_007497985  10 LNFEFWLNKAVAWGQTTTLESQQDVCLHLPQLQKFLQQIYETLKHMDFSM-AIDRFPLIGQLLGRLCWNPFVIGYDENQK 88 
XP_008101427  10 LSFEFWLHKTLKWGQSTTSESQQDVCLHLPELQEFLLQIYGALKHMNCRT-AVQQFPLVGQLLGRLCWNPLVIGYDECQK 88 
XP_015135800  10 LNFKFWLDKAIEWGQATTLESQKDVCLHLPQLQEFLHQTYETLKHMNSIA-AIQQFPLIGQLLGRLCWNPFVVGYDESQK 88 
XP_015223074  10 DLIEFWLDKAVEWGQATTFTSQQDVCLHLQKLRTFLQQLCQKLQTMNTTV-AMRTFPLVGQLFGRLCWNPYVIADEESQR 88 
XP_023199100  17 QQMPFWLEKAIAWGHTDTTHTRNDISLHLKRLRDFLQQLLSEISSVSSTTeTLNRLPLLGQLLGQLCWNPHVTAEGASRG 96 
XP_005452188  21 QEMQFWLDKAVAWGQADSPDTQKDTCLHMSRLRDFLQQLLTQVNSMSSTTeTMKRLPFLGQLLGRLCWNPYVTVCDTSRG 100
XP_022526809   7 LQVTFWMDKAVTWGQATSLSARLDTTKHLNSLRSFLQQLLEKLQSMSSTAeAMKNLPFVGQFLGRLCWNPYVTADGESSR 86 
AAI42140      10 SNYQFWMQKLSVWTQASTLETQRDICLHLPQFQEFLRRMYETLKEMDSNA-IIERFPTICQLLAKSCWSPFILAYDESPK 88 
XP_011613891  21 QEMQFWLDKAVAWGQAQTVETQRDTCQHLSRLRDFTQQLLKHINSMASTTeTMKRLPLIGQFLGRLCWIPSVTADASSRS 100
7KZP_C       114 ILIWCLCCLINKEPQNSGQSKLNSWIQGVLSHILSa----lRfdkEVALFTQGLGYAPIDYYPGLLKNMVLSLASELREN 189
XP_007497985  89 ILMWCLCCLYCSEPQNSIEVEANIWIRSLLCHLLSssklglN---EVGSVIQALGYTSPDYYPELLKNMVLSLVTELRVN 165
XP_008101427  89 ILMWCLCCLYSGEPQSPVELKANSWIQSSLCHLLSisglgsHn-tDLNSFISTLGFTSADYNSKLLENVVLSLVTELR-N 166
XP_015135800  89 TLMWCLCCLYSSEPQNPVELKANSWIRSLLCHLLSsskwerIe-aETSTFISALGYTSADYYCHLVENIVSSLVTELREN 167
XP_015223074  89 TLLQCLWCLYSAEPQNTVELKANDWLWNLLCHLISe----eDk-sAASTSLQTLSCIPEELHSNLVKDMVSSLVTELAGI 163
XP_023199100  97 LLLQCLLALYSEHPSNAVERKANQWIQKVLCHLATd----eEd-gAAVGLMKHLGVPTKEYHLKVLKKMVTRIQESIGNS 171
XP_005452188 101 LLLGCLWELYSERPSNAVEQKANQWIRKVLCQLSTe----eDd-tAAQALMKCTGVPAKEYHLKVLRKKVALLQENVGQS 175
XP_022526809  87 LLLQCVWHLYSVNPQNAVERRANEWIQNLLYHLTSe----eEg-sVGHALEKHSGSLNQHYYSETLKKMVALLTEEVSMN 161
AAI42140      89 ILIWCLCCLIKKDPQNSRESKLNSWTRRLLSHIVStsrfdiK---EVGLFNQVLGYAPTDYYPGLLKNMVLSLVSELREN 165
XP_011613891 101 LLLQCLWGLFSEHPGSAVERKANQWIRTVLCQLVTe-----Ed-aKVEPLIRQMGVAPKDYHLGVLRKRLALLQQNFEKN 174
7KZP_C       190 HLNGFNTQRRMAPERVASLSRVCVPLITLTDVDPLVEALLICHGREPQEILQPEFFEAVNEAILLKKISLPMSAVVCLWL 269
XP_007497985 166 HLNGFSIQKIIPERQIKAISLLCVPLLTLPDILPLLEALLTYHGGEPKEILSSEFLEGVNEAFLQKKIVLSESAVFSLWL 245
XP_008101427 167 QFNQFKSQQSIS-SRITSISLLCMPLITLPDVIPLVEALLSYHDGGSQEVLHSTFLEAVNKALLQKKISLSESAVVQLWL 245
XP_015135800 168 QFNELNIQERISVSRVNAVSLFCLPLITLPDLTPLLETLLLYHGGASKEILSSEFLEAVNDAVLKKKISLSESAIFSLWH 247
XP_015223074 164 CHNGIHMPARPLSDRLHSLSVLCLPLVTHPEAAPLIGTLLLCPEFGHNGALSAEFLEAVGKAVLEKKLVLDEPEVMSLWL 243
XP_023199100 172 RCSVSSTNKGCSCGSIWAASEACVPLITCPEASPLIGALLQQQMTCIREGLSENFLDALHSAYLRCDLLLDEQAVVSLWY 251
XP_005452188 176 C--TLFNSQRCSCDRIVAISEACIPIVACPEASSLISLLLQRPVACVTEVLSEDFLDALTSAYSRQGLALEEQALVSLWY 253
XP_022526809 162 CISSTPFTERCSCNRLRAVSVACVPLVTCPLVAPLTGALLKHQVSCGCSHLSEEFIEAVSTAWLSKKLVIEDLAVIALWC 241
AAI42140     166 HLNGFSSQRRMSPERVRSLSRICVPLLTLPDFEPLVEALLTYHGHEPQEVLCPEFFDAVNEAFLLKKISLPTSAILCLWL 245
XP_011613891 175 CNCLADKNQRCPHDDSLAVSESCIPLVTCQEAAPLINTLLQRPASCISAALSEDFLDALNSAHSRQSLLLEEQGIISLWY 254
7KZP_C       270 RHLPSLEKAMLHLFEKLISSERNCLRRIECFIKDSSLPQa-ACHPAIFRVVDEMFRCALLETDGALEIIATIQVFTQCFV 348
XP_007497985 246 RHLPSLEKATLHLFEKLTSRYINIPEELEGVIKDSLLPQa-ACHPSIFRIVDEIFRNALLETNGTSEVLTIIQVFTQCFV 324
XP_008101427 246 RHLPSLEKAVLQTLGNLISSQPCSVQEMACLIKDSLLDRa-ACHPAIFRTADEILKNALLETDGAPEVMTVMQVFTQCFV 324
XP_015135800 248 RHLPSLESATLSLLDQLTSLQINSLEKVACVIKDSLLPQa-ASHPAIFRIVNEIFKNALLETDGAPEVMTIIQVFIQLFI 326
XP_015223074 244 RCLPSLEKATLHLIDSLVSNESLLPQDMEHLMMDSLLPKasAYHAPIFLTVKDIFRQMLLESSENTPVQSIIRLFTRCFV 323
XP_023199100 252 QSLPSLEEAVLNLLESATTA-GSTPSKVEEQVPKSLLPKacAQHCSVFLVVNDIFRTVLKQNERNERVKNVFQTFTKCFF 330
XP_005452188 254 HSFSSLEEAVLSLLQSVITT-GLTPQKLEQQVAQSLLPKacAQHCSVFLVVNDIFRSVLKQAEVNEFVKALVQTFTKCFL 332
XP_022526809 242 HSLSSLERAVLSLLESVLSDQGSVMQSLEKTVTDSLLPKasALHCHLSLLVNDVFRNVLMTMEENLAVRSLIQVFTACFL 321
AAI42140     246 RHLPSLENTMLHLLEKLISSERNSLRRIKCFMKDSLLPEaaACHPAIFRVVDEIFRSALLETDGAPEVLAGLQVFTRCFV 325
XP_011613891 255 HNLPSLEEAVLRLLESVLANNESSPQKLEQLLEQALLPKacAQHCSMFLVVNDIFRSFLKQAERAESVHCLIHTFTRCFL 334
7KZP_C       349 EALEKASKQLRFALKTYFPYTSPSLAMVLLQDPQDIPRGHWLQTLKHISELLREAVEDQT--------------HGSCGG 414
XP_007497985 325 QAFQKDSKQLKFPLKSYFPYASPSLVMILLQDPEDLPRGLWCQHLNHISKTLKNIVEDQS--------------TQSCGS 390
XP_008101427 325 QAYHENNKQHKFPLKAYFPQNPHLLVMVLFKDPADLSAKGLHQHLNHIAEILKTTVETKG--------------VRSCGN 390
XP_015135800 327 QVQQNENKQHKFPLKAYFPHHHQPLVIALLRRPFELPSTHWLQHLKHISDTLKSIVEDTN--------------VSSFAD 392
XP_015223074 324 QSLLLEDMQERLPLKVFFPHHPQSLVMALLKLPSEVPSHVWEEHLKWISWTLRNVVEVEEl-------------TGSCQR 390
XP_023199100 331 MELSRLQPQTSASLKAFFPQSPPSLLIPLFTMPSEMPQESLKNHLIWVSSSLQRLTEEEEdeeds-----dssnIRGNHK 405
XP_005452188 333 KELALLKPQTSISVKAFFPQSPSSLLVPLLTMPSEMPQGAWRNHLNWLSSSLQRLTEEEEegdg------dgrsTRGHHN 406
XP_022526809 322 QIRTDQNPEERPPLKAFFPHVPQSLLTPLLTTPSEVPKQAWLQHLCWIRELVQEILCERNgeeegkekeeeeksRRQRRA 401
AAI42140     326 EALEKENKQLKFALKTYFPYASPALVMVLLQHPKDIPQGLWHQSLKHISEMLKEIVED----------------HGSYGG 389
XP_011613891 335 RELALVPHQNSVPLKALFPQSPQSLLMPLLTLPSEMHQEAWRHHLKWLSDSLRRLTEEEEeddrdg---srsscLKSHHR 411
7KZP_C       415 PFESWFLFIHFGGWAEMVAEQLLMSAAEP--PTALLWLLAFYYGPRDGRQQRAQTMVQVKAVLGHLLAMS--RSSSLSAQ 490
XP_007497985 391 PFEQWFLFIHFGEWADIAAEELLMWRAES--PEALLWLLAFYYNPHDQNQEWIQTMVDVRAVHGHIMKLF--DRTPLSVK 466
XP_008101427 391 LFENWLLLVHFGEWVDIAAEQLVVSQCES--SGALLWLLVFYYEPSDENQRRTQTMREAKSVCDHLTTLS--RASTISVP 466
XP_015135800 393 LYEIWFLVACFGEWLDIAAEQLMKAAVA---PDALLWLLAFYYCPQNENQQRTQTMVESQAVYSRLMMLY--NRTVLSFG 467
XP_015223074 391 LFENWFLLVQCGDWVDVAAQHLTASDSET--SGALLWLLAFYHHPNNESQQRSESLAVARGVCDHLKSLF--ASAPPTAA 466
XP_023199100 406 VFEAWFLLVQCGYWVQVVVQLLVTSGPED--CGPLLWLLTFYHHPTNRWHHRASQLVQAKAAWDHLYSLFsiEAHLLPAD 483
XP_005452188 407 VFEAWFLLVQCAHWVQVAVQLLVTSGTED--GDPFLWLLIFYHYPTNRWHHRASQLARAKEAWNHIRTLFsgAAHPLPSD 484
XP_022526809 402 VFETWFLLVQCGHWVDAAAELLVSVGSEE--SEPLLFLLTFYHHPTNRGHQNTQQTMVAREAWSHLRILF--LTHTPPPE 477
AAI42140     390 PFESWFLFVHFGGWADITAEQLLMSEAEAepPEALLWLLAFSCSPGAGHQQRARTMVEVKTVLGCLTKLF--RSPALSAR 467
XP_011613891 412 VFEAWFLLVQCVHWVQLTAQLLVTSETQD--CGPLLWLFTFYYHPTNRGHHRASQLGHAKEALDHLRALFspLNPPLPVG 489
7KZP_C       491 DLQTVAGQGTD--TDLRAPa-QQLIRHLLLNFLLWAPGGHTIAWDVITLMAHTAEITHEIIGFLDQTLYRWNRLGIESP- 566
XP_007497985 467 DLQAVAGESSE--DGTRQPstQRFIRHLLLNFLLFSSEGHTIAQEFI--ITQTDEIIDEFLNLIARAKSRWERLGMETP- 541
XP_008101427 467 ELEVVT--SSR--IDARCPgtKHLIRHLIVSFLLFTPGGHTIAREFIDGFAVGSSEILEVIGLLTCISNRVSQDGVKYQ- 541
XP_015135800 468 DLQASVNNAA----DTEQChtQCLITHLLTNFLLFSSGGHMIAQEFISHITETTDMSKEVCSLLIRTAYRIKHNGGENQ- 542
XP_015223074 467 HLETLLSLAAT---DSQQCrtPHLIDQLAVNFVVFSEGGNAVAKEVVRAMMHWSS-RKVVSALKAGIEHRLNRYGLMDF- 541
XP_023199100 484 HLQSFISLLAP--KPQQPSlaPSLTLSLLVNFATFGQLPQSISAEITQKVVHQSGLQDEATRVLSSLRLRLNDRGSFANd 561
XP_005452188 485 RLQSLVTLVSP--QPEQQSlaPSLTVSLLVNVAVFCQLPPSGSAEVLQAVVDQSGLLDEAACVLSSLELRLNEGSCLSRd 562
XP_022526809 478 KLSPVQELLSS-------MfsTNLVLHLLLNFAVFSQASASSVSEVIQKLLMEAGMRRKAAWILSSVQHRLNRADLLDA- 549
AAI42140     468 DLQAAAGENLG--GDPRPPacQQLVRRLLLHFLLWAPGGHTIAREVITLMAQTDAIMNEIIGFLDYTLYRWDHLCVEAH- 544
XP_011613891 490 SLQSVMTLLSPaqQQQQQSlsTLLIINLLVNFAVFSRQSLIGSAEVLQMVVDQSGLLNEAARVLVSLELSLNRGRHLSSd 569
7KZP_C       567 --RSEKLARELLKELR 580
XP_007497985 542 --RTGKLARDLLQELQ 555
XP_008101427 542 --RTIKLANDLLQRLK 555
XP_015135800 543 --RTVKLLNELLQKLA 556
XP_015223074 542 --KAHSRLKIMQEVLQ 555
XP_023199100 562 --RVHLRIEELHNTIK 575
XP_005452188 563 --TVHLRIKELQKTIt 576
XP_022526809 550 --RVHSRLKTLQDSLA 563
AAI42140     545 --RSRKLARELLTELR 558
XP_011613891 570 tnRVQLRVQKLQHTLT 585
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