3L0A


Conserved Protein Domain Family
DUF3799

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pfam12684: DUF3799 
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PDDEXK-like domain of unknown function (DUF3799)
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 265 and 420 amino acids in length. It appears that these proteins are distantly related to the PDDEXK superfamily and so these domains are likely to be nucleases. This family has a C-terminal cysteine cluster similar to that found in pfam01930.
Statistics
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PSSM-Id: 432717
Aligned: 24 rows
Threshold Bit Score: 202.149
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3L0A_A            20 SVSGYKDFAGtygkxpCEFYGXEKLNGRWED------EKSTALLVGSYVDSY-FEGSL--DQFKK----------DNPEI 80  [Eubacteriu...
jgi:Rpic12D_5087  48 SSTQLKSILK------TPKHFLAAVQGAG--------KDKQVLEFGRLAHMAvFEPWRfeDMVLPydgefdrrlrNCKTF 113
Q12DB2            51 SCSMLKPLLE------SPAHFQAHLLSLN--------KATKAMDFGSLVHGLvLEPHLigTEFSIypgiadgraaEYKSF 116 Polaromonas...
CDE30498          13 SKSDLDLAHR------SPMHYQYRKEHPQG-------SQTPALLIGSAVHKMvLESSTfdEEFAVlddaidrrtkAGKEA 79 
jgi:Galf_0946     20 SHSGIVQLLK------SPEHYKNYKEGIV--------EPTPAMEFGSACHSFiLEPELfaKEYVLapkfd-krtkDGKEA 84 
Q9CIB7             6 SFSSLKAFSD------CEAEAVAVMAGDWDRqatfspSTIEAMNAGSYVHKY-FESNKalEEFKL----------EHESD 68  Lactococcus...
Q832T7            26 SVSQYKNFNE------CEAATIARLKKIWLPc-----SDPKALLVGNYVHSY-FESSKihDLFKK----------ENKDK 83  Enterococcu...
BAH17617          19 SVSTFKKFSQ------CEAAAMAFLTGEYKQ------SSSPAMLVGNFVHSA-FDSEEehEKFVN----------EHSKV 75 
CCC78120          38 SATWFKKFLA------CEAEALAELTGKWQPv-----RDAKALVVGNWLHSY-FESKQahEKFKD----------EHPES 95 
jgi:Lreu_0812     19 SVSLFKDFEK------CEARALAKLKEDWQPv-----SSPVPLLVGNYVHSY-FESAKshQDFIE----------ANKKE 76 
3L0A_A            81 FTQ-------KGELKAN-FKQAEEIIARIERDEYFXK----YXS-G-QKQVIXTGELF-GAKWKIKXDSYIPg-VAIVDL 144 [Eubacteriu...
jgi:Rpic12D_5087 114 IADhpn----hivIGQDkFDALLSMREAVRAHHFRGRtlgeWFDeGeQEKAIYFVERVtNVKCRIKVDNLHP--EFIFDL 187
Q12DB2           117 LTKhas----rlvVDEPtFARARKLAEKILHRIVFGRpfgdFVNeGiPEASIYVEEPTtGLMLRTRLDLYHP--EYSFDL 190 Polaromonas...
CDE30498          80 YSTfleqsagKFILTQEiYQQAMDMADAVHHHPTARK----LLTgGkAEQSYFWEDLRtGLPCKCRPDYLRP--GFCVDY 153
jgi:Galf_0946     85 AAKwdeenvgKIPLAAEqIDALAAMRVSVFNHTGTAK----ILSaGeAETSLFWTDEYtGLQCRIRPDWMFD--RGIADL 158
Q9CIB7            69 MFTk------KGSLKSQ-FQIAEKMVQTLDHDPLFKT----IYQ-G-VKELEIFGKIQ-GIEFHGFLDCLNLerNIFIDI 134 Lactococcus...
Q832T7            84 MFSsr---kpYGLLKD--FQIAEQMIQRLKEEPAFMN----LYK-G-EKEVIVTGQIE-NVNWKGKIDCLNLedGYFVDI 151 Enterococcu...
BAH17617          76 IFNr------KGDYYKD-YAVAKQMIEALKNDELAMF----ALE-G-EKEVILTGELF-GIQWKCRIDSINHerKTFADI 141
CCC78120          96 ISKrg---ptKGQLKSD-FKVANAMIQSLTNDHDFNL----LYQ-G-DKEVIVTGEIG-GYPWKGKIDCLNLkqGYFVDL 164
jgi:Lreu_0812     77 LMTrptktnpNGHLRAE-FKGANSMIQTLQADDMFNY----FYApG-DKEVIVTGEID-GYLWKGKIDSLVLdkGYFCDL 149
3L0A_A           145 KVXA-SITDLKWVKDIGyldf-vryWGYDIQGAVYQEIVRQ----NTGEK--LPFFIAGATKQTEPDIRIIHV----TDN 212 [Eubacteriu...
jgi:Rpic12D_5087 188 KSTV-DVRPAAFNGSVHa-------YHYDLSAFMYQTGVQY----FTGEE--RPFVFIAVEKEAPYSVMTYTA----GDS 249
Q12DB2           191 KTTR-HGTINAFIRDAVd-------LHYDFQAFMYTIARSL----YEGRTtpAKFVFIAAETEAPSSIHQITA----GQS 254 Polaromonas...
CDE30498         154 KTTQ-DASLEAFQRSAYk-------YRYNVQAYWYLHGLRL----NGMQD--LDFVFIAQEKEPPYAIAIYYA----DAA 215
jgi:Galf_0946    159 KSCI-TASKDGFSKAVAn-------LGYDVQAAFYIDGMKA----VTGKT--VNFYFIAVEKSAPFSTACYMA----SQE 220
Q9CIB7           135 KTIRgSIRDKEWSEIEYrrvswikaRKYLWQMAIYQEILRQsddeKIGKN--ISPVIYAVTKETFPDSAGITI----PQE 208 Lactococcus...
Q832T7           152 KTTK-DIHERKWNDSYAerctfienYGYVLQMAVYKELLSQ----KYNRE--FVPIIAAVSKQTPSEVKLITL----DED 220 Enterococcu...
BAH17617         142 KTTQ-DLHKRIWSDKHGgyvsfveaYDYIFQMYIYRELIFQ----KFGEY--YEPYIVAVTKETPSNKAVIEIa--hDRY 212
CCC78120         165 KTTA-DIYKVYWNPETRekesfvyaYNYPLQMAVYQELIKQ----QFGVT--CKPYIVAVSKQDPPDKQAIDL----PEY 233
jgi:Lreu_0812    150 KTVD-DIHKGHWNTYEHryvpfiqdREYDLQMAVYRELIKQ----TFGKK--CQPLIFAISKQTPPDKMAIDFngvdDDY 222
3L0A_A           213 YLQEALHXVEXNXPRILRVKNGEVEPDR--CELCDCCRHN 250 [Eubacterium] rectale ATCC 33656
jgi:Rpic12D_5087 250 LLDNGAQKFEDGLNRLNHARAHDSWPGY-----------A 278
Q12DB2           255 FMSNGAKKFQEVLSVYTACMQTGFWPDS--SGNAEAEIEP 292 Polaromonas sp. JS666
CDE30498         216 TLKLGQIDAEADLEALSSCIHAGVFDGY--TNEIQPLTPP 253
jgi:Galf_0946    221 MVEVGRAKYRGALELLKWCQENSRFPGYqpSGEIESIDLP 260
Q9CIB7           209 WLDDSLDEVCEFTDKYIEVLNGRV-PVR--CEQCNYCKAT 245 Lactococcus lactis subsp. lactis
Q832T7           221 KMHFEMIQLKENIEHIIKVKNGEEKPTL--CGRCEYCRGQ 258 Enterococcus faecalis
BAH17617         213 TFESSFAEVTMK-DDILPLLKKERQPDR--CEKCEYCRQT 249
CCC78120         234 RLTNAMNQVLESQQHLQDIIKGEADPIQ--CGHCAYCRST 271
jgi:Lreu_0812    223 QMQADLDKVKELQPHFWKVMTGEEEPVH--CGKCDYCRET 260
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