1GSZ


Conserved Protein Domain Family
hopene_cyclase

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TIGR01507: hopene_cyclase 
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squalene-hopene cyclase
SHC is an essential prokaryotic gene in hopanoid (triterpenoid) biosynthesis. Squalene hopene cyclase, an integral membrane protein, directly cyclizes squalene into hopanoid products. [Fatty acid and phospholipid metabolism, Other]
Statistics
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PSSM-Id: 273661
Aligned: 4 rows
Threshold Bit Score: 1119.59
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1GSZ_A         1 MAEQLVEAPAYART--------LDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDRVDRDRMEKIRRYLLHEQ 72  Alicyclobacillu...
CAA71098       6 TAISNLEPPLTASYvespldaaIRQAKDRLLSLQHLEGYWVFELEADCTIPAEYILMMHFMDEIDAALQAKIANYLRHHQ 85  Methylococcus c...
WP_010872605   4 AASPSVPCPSTEQVrq-----aIAASRDFLLSEQYADGYWWSELESNVTITAEVVILHKIWGTAAQRPLEKAKNYLLQQQ 78  Synechocystis s...
BAA25185       1 MAEQLVEAPAYART--------LDRAVEYLLSCQKDEGYWWGPLLSNVTMEAEYVLLCHILDRVDRDRMEKIRRYLLHEQ 72  Alicyclobacillu...
1GSZ_A        73 REDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEEPMQKALRFIQSQGGIESSRVFTRMWLALVGEYPWEKVPMVPPEI 152 Alicyclobacillu...
CAA71098      86 SADGSYPLFRGGAGDISCTVKVYYALKLAGDSIDAPHMKKAREWILAQGGAARSNVFTRIMLAMFEQIPWRGIPFTPVEI 165 Methylococcus c...
WP_010872605  79 RDHGGWELYYGDGGELSTSVEAYTALRILGVPATDPALVKAKNFIVGRGGISKSRIFTKMHLALIGCYDWRGTPSIPPWV 158 Synechocystis s...
BAA25185      73 REDGTWALYPGGPPDLDTTIEAYVALKYIGMSRDEEPMQKALRFIQSQGGIESSRVFTRMWLALVGEYPWEKVPMVPPEI 152 Alicyclobacillu...
1GSZ_A       153 MFLGKRMPLNIYEFGSWARATVVALSIVMSRQPVFPLPERARVPELYETDVP-PRRRGAKGGGGW--IFDALDRALHGYQ 229 Alicyclobacillu...
CAA71098     166 MLLPKWFPFHLDKVSYWSRTVMVPLFILCSHKVTARNPSRIHVRELFTVEPQkERHYFDHVKTPLgkAILALERFGRMLE 245 Methylococcus c...
WP_010872605 159 MLLPNNFFFNIYEMSSWARSSTVPLMIVCDQKPVYDIAQGLRVDELYAEGMEnVQYKLPESGTIWd-IFIGLDSLFKLQE 237 Synechocystis s...
BAA25185     153 MFLGKRMPLNIYEFGSWARATVVALSIVMSRQPVFPLPERARVPELYETDVP-PRRRGAKGGGGW--IFDALDRALHGYQ 229 Alicyclobacillu...
1GSZ_A       230 KLSVHPFRRAAEIRALDWLLERQAGDGSWGGIQPPWFYALIALKILDMTQHPAFIK-GWEGLELYGVELDYGgWMFQASI 308 Alicyclobacillu...
CAA71098     246 PLIPKAVRKKATQKAFDWFTARLNGVDGLGAIFPAMVNAYEALDFLGVPPDDERRRlARESIDRLLVFQGDS-VYCQPCV 324 Methylococcus c...
WP_010872605 238 QAKVVPFREQGLALAEKWILERQEVSGDWGGIIPAMLNSLLALKVLGYDVNDLYVQrGLAAIDNFAVETEDS-YAIQACV 316 Synechocystis s...
BAA25185     230 KLSVHPFRRAAEIRALDWLLERQAGDGSWGGIQPPWFYALIALKILDMTQHPAFIK-GWEGLELYGVELDYGgWMFQASI 308 Alicyclobacillu...
1GSZ_A       309 SPVWDTGLAVLALRAAGLPADHD----RLVKAGEWLLDRQIT--VPGDWAVKRPNLKPGGFAFQFDNVYYPDVDDTAVVV 382 Alicyclobacillu...
CAA71098     325 SPIWDTALTSLTLQEVARHTADLrldaALSKGLKWLASKQIDkdAPGDWRVNRAGLEGGGWAFQFGNDYYPDVDDSAVVA 404 Methylococcus c...
WP_010872605 317 SPVWDTAWVVRALAEADLGKDHP----ALVKAGQWLLDKQIL--TYGDWQIKNPHGEPGAWAFEFDNNFYPDIDDTCVVM 390 Synechocystis s...
BAA25185     309 SPVWDTGLAVLALRAAGLPADHD----RLVKAGEWLLDRQIT--VPGDWAVKRPNLKPGGFAFQFDNVYYPDVDDTAVVV 382 Alicyclobacillu...
1GSZ_A       383 WALNTLrlpDERRRRDAMTKGFRWIVGMQSSNGGWGAYDVDNTSDLPNHIPFCDFGEVTDPPSEDVTAHVLECFGSFGYD 462 Alicyclobacillu...
CAA71098     405 HALLGS---EDPSFDDNLRRAANWIAGMQSRNGGFGAFDADNTYYYLNSIPFADHGALLDPPTADVSARCAMFLARWVNR 481 Methylococcus c...
WP_010872605 391 MALQGItlpDEERKQGAINKALQWIATMQCKTGGWAAFDIDNDQDWLNQLPYGDLKAMIDPSTADITARVVEMLGACGLT 470 Synechocystis s...
BAA25185     383 WALNTLrlpDERRRRDAMTKGFRWIVGMQSSNGGWGAYDVDNTSDLPNHIPFCDFGEVTDPPSEDVTAHVLECFGSFGYD 462 Alicyclobacillu...
1GSZ_A       463 DA--WKVIRRAVEYLKREQKPDGSWFGRWGVNYLYGTGAVVSALKAVGIDTREPYIQKALDWVEQHQNPDGGWGEDCRSY 540 Alicyclobacillu...
CAA71098     482 QPelRPVLERTIDYLRREQEADGSWFGRWGTNYIYGPGAVLLAYEGRRVPNDDPSVRRAVAWLKSIQREDGGWGEDNFSY 561 Methylococcus c...
WP_010872605 471 MD--SPRVERGLTYLLQEQEQDGSWFGRWGVNYLYGTSGALSALAIYDAQRFAPQIKTAIAWLLSCQNADGGWGETCESY 548 Synechocystis s...
BAA25185     463 DA--WKVIRRAVEYLKREQKPDGSWFGRWGVNYLYGTGAVVSALKAVGIDTREPYIQKALDWVEQHQNPDGGWGEDCRSY 540 Alicyclobacillu...
1GSZ_A       541 EDPAYAGK-GASTPSQTAWALMALIAGGRa---------ESEAARRGVQYLVETQRPDGGWDEPYYTGTGFPGDFYLGYT 610 Alicyclobacillu...
CAA71098     562 HDPSYRGRfHTSTAFQTGFALIALMAAGEx---------GSPEVQAGVDYLLRQQRPDGFWNDECFTAPGFPRVFYLKYH 632 Methylococcus c...
WP_010872605 549 KNKQLKGQ-GNSTASQTAWALIGLLDALKylpslgqdakLTTAIEGGVAFLVQGQTPKGTWEEAEYTGTGFPCHFYIRYH 627 Synechocystis s...
BAA25185     541 EDPAYAGK-GASTPSQTAWALMALIAGGRa---------ESEAARRGVQYLVETQRPDGGWDEPYYTGTGFPGDFYLGYT 610 Alicyclobacillu...
1GSZ_A       611 MYRHVFPTLALGRYKQAIER 630 Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446
CAA71098     633 GYDKFFPLWALARYRNERYA 652 Methylococcus capsulatus str. Bath
WP_010872605 628 YYRQYFPLIALARYSHLQAS 647 Synechocystis sp. PCC 6803
BAA25185     611 MYRHVFPTLALGRYKQAIER 630 Alicyclobacillus acidocaldarius
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