Conserved Protein Domain Family
rpoB

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PRK00405: rpoB 
DNA-directed RNA polymerase subunit beta; Reviewed
Links
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Statistics
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PSSM-Id: 234749
Aligned: 973 rows
Threshold Bit Score: 1603.99
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
118579112    1 MAYSIANNHLLRKTFTKIKNIIDIPNLIDIQKNSYRRFLqqegvsesrnNTGLEAVFRSVFPIKDFSESASLEYVSYSLs 80  
83319487     3 YKIRKINRNVERRDYTKVSMNLSLPNLIGIQTETFEWFK----------TKGIQEVLDEFFPILSFDGSSVLTLENWGFk 72  
42561522     3 YKIRKINRNVERRDYTKVSMNLSLPNLIGIQTETFEWFK----------TKGIQEVLDEFFPILSFDGSSVLTLENWGFk 72  
13357745     7 YTEKFITDKVMRRDYSKIKSNFEGPNLLEIQVESFKRFM----------EKDLKEVISSIFPLKSPQGKYTLAFKGLKIk 76  
170761945    7 YTEKFITDKVMRRDYSKIKSNFEGPNLLEIQVESFKRFM----------EKDLKEVISSIFPLKSPQGKYTLAFKGLKIk 76  
162447041    3 YKTVKYGKKAERRDYSKMLHQVELPNLIEIQTKSFEEFV----------ETGIDELLKDISPIEGHNGDLKLYFEESSL- 71  
39938746     3 YHNVKYGKKAQRRNYSKTIYDVDLPNLIEIQNQSFDWFL----------KHGIKELLQDFCPIESYNGDLKIHFDDYFLa 72  
197294699    3 YRNVKYGKKVERRNYSKIIYDVDLPNLIEIQNKSFNWFL----------KDGIEELLQDFCPIESYNGDLKIYFGECYS- 71  
85057741     3 YHNVKYGKKAQRRNYSKTIYDVDLPNLIEIQNQSFDWFL----------KHGIKELLQDFCPIESYNGDLKIHFDDYFLt 72  
50365415     3 YKIKKVNRGVERRDYRKVSGNLELPNLIEIQTKTFEWFK----------TKGIDEVLNEFFAMSSNDASASLFLEGWEIk 72  
118579112   81 K-PKYDVVECHQRGMTFAAPMKVKVRLViwdtg--------------------kesgIRAIK-DI--------------- 123 
83319487    73 -ePRLSVRQAREESKIYDAPIYANLKLSvnkteeiqkefdgvdqedtlkvlthwleeKTGNG-NItfkqqsqnsyffeit 150 
42561522    73 -ePRLSVRQAKEESKIYDAPIYANLKLSvnkteeiqkefdgv-vlddalqilskwleEKTVSkNItfkqqsqnsyffelt 150 
13357745    77 -qPTKDESACRDEGKTFETPIYIDLELT-----------------------------DNYTG-EVk-------------- 111 
170761945   77 -qPTKDESACRDEGKTFETPIYIDLELT-----------------------------DNYTG-EVk-------------- 111 
162447041   72 SePKYSTIETKIRDLNYSRQLSARVKLE-----------------------------NAITG-EV--------------- 106 
39938746    73 -pPKYSIEETKIKDISYVAQLFVKTTLE-----------------------------NVLTG-ET--------------- 106 
197294699   72 TgPKYSVEESKTKDASYVIQLFVKATLE-----------------------------NTLTG-ET--------------- 106 
85057741    73 -pPKYSIEETKIKDISYVAQLFVKTTLE-----------------------------NVLTG-ET--------------- 106 
50365415    73 -eAKISPSKAKEQSKIYDAPIYVDLQLMftktediskefeeivekdvkkvlsnwiaeKTDSK-NVslvkntdniyffdvk 150 
118579112  124 -----------------------------K--------EQEVYFGEIPLMTDNGTFIINGTERVIVSQLHRSPGVFYDHD 166 
83319487   151 ikksekpdliqidiiedkktslicnvsiyK--------SGEVFLGDFPLMTEAGTFIINGSQKVIVSQLVRSPGAYFNKE 222 
42561522   151 ikksekpdliqidiiedkktslicnvsiyK--------SGEVFLGDFPLMTEAGTFIINGSQKVIVSQLVRSPGAYFNKE 222 
13357745   112 -----------------------------RaqrntktgEDGIYLGAIPKMTEKGTFVINGIEKFVISQIVRSPGIYVLGK 162 
170761945  112 -----------------------------RaqrntktgEDGIYLGAIPKMTEKGTFVINGIEKFVISQIVRSPGIYVLGK 162 
162447041  107 -----------------------------R--------ESTVLMTDLPMMTPSGTFIINGAERVVVSQIVRSSGVYYTSE 149 
39938746   107 -----------------------------K--------QSNILLTELPLMTPTGTFVINGTERVVVSQIVRSASVYFAGN 149 
197294699  107 -----------------------------K--------KSSVLLTELPLITDTGTFIINGKERVAVSQIVRSSSVYYSST 149 
85057741   107 -----------------------------K--------QSNILLTELPLMTSTGTFIINGTERVVVSQIVRSASVYFAGN 149 
50365415   151 lkgtekndlfqitileekediivaevsvrK--------WGQVFFGDFPLMTDAGTFVINGSQKVIVSQLVRSPGSYFKTE 222 
118579112  167 KG-KTh-SSGKVL--YSARVIPYRGSWLDFEFDHKDI-------LYVRID---RRRKMPATVLLKALGY-SAEQLLNYYY 231 
83319487   223 LNrKT----GEMI--YFADIIPSRGTWLEYETDSKKIgsdainpLYVKID---KSRKTTATSLLLAFGI-SKDDILNIF- 291 
42561522   223 LNr----KTGEMI--YFADIIPSRGTWLEYETDSKKIgndainpLYVKID---KSRKTTATSLLLAFGI-SKDDILNIF- 291 
13357745   163 SSiKLngSRKRLFegKICEIYPSKGTLML-GYIPKDRhn---iqIVARDSsgdNAQTFSVTTLLKAFGL-TSAEILKIFN 237 
170761945  163 SSiKLngSRKRLFegKICEIYPSKGTLML-GYIPKDRhn---iqIVARDSsgdNAQTFSVTTLLKAFGL-TSAEILKIFN 237 
162447041  150 LDkKI----NQIK--YSAQVIPTRGAWIEFEQGSKEI-------LYAKLD---RSKKVPLTTFIRALGFtTKKDIEETFG 213 
39938746   150 FDsKL----NRTT--YSGQVIPSRGAWIEYEEGSKEI-------LYAKLD---RSKKIPLSNFIYALGF-DSKEAIENVF 212 
197294699  150 FDvKL----NKNL--YSGQVIPARGAWIEYEEGSKEI-------LYVKLD---RSKKIPLSNFIYALGF-NNREIIEKVF 212 
85057741   150 FDiKL----NRTI--YSGQVIPSRGAWIEYEEGSKEI-------LYAKLD---RSKKIPLSNFIYALGF-DSKEAIENVF 212 
50365415   223 INn----KTGESL--YNGDIIPSRGTWLEFETDTKKTaet-tnsLFVKID---KSRKTTATSFLKILGL-DRDTILNIYD 291 
118579112  232 KSEEIFltgetpsksidaelltlqkalvdvvdpksgevivkanrkftkasirkmvehdiKAVPITFDSIIGRYASSDVID 311 
83319487   292 -----D-------------------------------------------------------------------------- 292 
42561522   292 -----D-------------------------------------------------------------------------- 292 
13357745   238 NEKEIResleiekya-----------------------------------peyifensqENEIIFKIYSDAHDIHEKADR 282 
170761945  238 NEKEIResleiekya-----------------------------------peyifensqENEIIFKIYSDAHDIHEKADR 282 
162447041      --------------------------------------------------------------------------------     
39938746   213 G------------------------------------------------------------------------------- 213 
197294699  213 GKSPLL-------------------------------------------------------------------------- 218 
85057741   213 G------------------------------------------------------------------------------- 213 
50365415       --------------------------------------------------------------------------------     
118579112  312 PATGEVLLECNEEVTAEKfdeikakgves--------frllfidnlhITSSF--RDTLLMD-----K----ISTNDEALI 372 
83319487   293 -----------------------------------------------NDEVL--VETLQQDsiigdF----KIDWSNQVQ 319 
42561522   293 -----------------------------------------------NDEVL--VETLQQDsiigdF----KIDWSNQVQ 319 
13357745   283 RESNNKLKEEYIEQGSPLlsklkqlifnyvekndeidallhenkdveDASFIknNKKLY-DereeiInciiSEKAAKDIV 361 
170761945  283 RESNNKLKEEYIEQGSPLlsklkqlifnyvekndeidallhenkdveDASFIknNKKLY-DereeiInciiSEKAAKDIV 361 
162447041  214 -----------------------------------------------RSSLI--TNTFEKD-----E----TKSPNEAVI 235 
39938746   214 -----------------------------------------------KSAII--DSVFDKE-----T----DMDSDNALV 235 
197294699  219 -----------------------------------------------NSSFV--KEE---D-----------MDTGNALI 235 
85057741   214 -----------------------------------------------KSAIL--DSVFDKE-----T----DMDSDNALV 235 
50365415   292 -----------------------------------------------KDKVI--VETLKNDndtgdT----YADWAQHVQ 318 
118579112  373 EI----YRRLRPGDPPTLKSSLALFENLFFNPERYDLSAVGRLKLNFKLGLkvwpectvlnapcmfgaediasfdelfrl 448 
83319487   320 EI----YKKIRQGETATSEGASKFINSILFDKRKYDLTKAGRFKLKQKLSIknrilnkviaedildannnvliakdtevt 395 
42561522   320 EI----YKKITQGETATSEGASKFINSILFDKRKYDLTKAGRFKLKQKLSIknrilnrviaedivdannnvliakdtevn 395 
13357745   362 ELlginIKNIETLRHLGKASYQIALQQHFFNKRLYDISSAGRYKFEKKLLLserlyqkviandiidkknnilipkdtlit 441 
170761945  362 ELlginIKNIETLRHLGKASYQIALQQHFFNKRLYDISSAGRYKFEKKLLLserlyqkviandiidkknnilipkdtlit 441 
162447041  236 DL----YSKLRQGEKVPADAAREFIRMRLFDARRYDLAKVGRYKFIKKLDVlaraegtylandiildgevlvakdthltk 311 
39938746   236 EL----YSKIRQGEKVPVDTARDFIRTRLFDQKKYDLAKVGRYKFNKKLDVltraentylacdfvnpetqeiiiaqdell 311 
197294699  236 EL----YSKIRQGEKVPVDTARDFIRKRLFDQKKYDLTTVGRYKFNKKLDVlaraektylvhdfvnletkeiilpkhtfl 311 
85057741   236 EL----YSKIRQGEKVPVDTARDFIRTRLFDQKKYDLAKVGRYKFNKKLDVltraentylacdfvnpenqeimiaqdell 311 
50365415   319 EI----YKKIRQGETATSDGASKYINGLLFDRRKYDLTKAGRFKLQQKLAVknrlmgrilaedivdasgkilvaknteis 394 
118579112  449 l------------------------------------------------------------------------------- 449 
83319487       --------------------------------------------------------------------------------     
42561522       --------------------------------------------------------------------------------     
13357745   442 kehielikkes--------------------------------------------------------------------- 452 
170761945  442 kehielikkes--------------------------------------------------------------------- 452 
162447041  312 eviqilaqnrdafrkqlitkennlqnetadeilattlpeggntly-----------------akenvvnlktgevlvkkn 374 
39938746   312 tkekiailkqnrhfllqeifdakhnlenetdeeilaykkdpqknelftktniinsrtgevlvakdtlvnddiinhlrhni 391 
197294699  312 tkdkieilrknrhfllqelfdaqhnlenetdeeiltykkdpqsrelyiktnilnfrtgeiifpkdtlvtdevikrlrksi 391 
85057741   312 tkekiailkqnrhfllqeifdakhnlenetdeeilaykkypqknelftktniinsrtgevlvakdtlvnddiinhlrhni 391 
50365415   395 kanikevsdalsq------------------------------------------------------------------- 407 
118579112  450 -------------------------laadnrfsqyvlarlpedfvkvlrkhepsQpVAEKLreqllkelNN--------- 495 
83319487   396 -------------------------knniqeiskildqdvmsidlkylsdipgnR-KVQKI--------RV--------- 432 
42561522   396 -------------------------khnikqiseildqdvmsidlnylsdipgtR-KVQKI--------KV--------- 432 
13357745   453 -----------------rdknikwtkkinllptaleseieqfleyesiavykdndlRDETT--------EIvglasgckl 507 
170761945  453 -----------------rdknikwtkkinllptaleseieqfleyesiavykdndlRDETT--------EIvglasgckl 507 
162447041  375 eaiteevltnlrknrhsidekvikyfltedvykkeslrqgviseildvyvyddagdKSNVI--------RIigsdqredr 446 
39938746   392 htldekvskfflgtkdiyqkeadrqgvfneilevytskdesgklyhkvkligndQ-RE-TK--------KH--------- 452 
197294699  392 qlldgkviefflrskdvyqkdlertgvfneilevylskdehdnlqhkvqivgnnQkETKKH------------------- 452 
85057741   392 htldekvskfflgtkdiyqkeadrqgvfneilevytskdesgklynkvkligndQ-RE-TK--------KH--------- 452 
50365415   408 ------------dgvmvssieyredipgsrqiqkvkvyqdnnskdetftivgitPnSKEEH------------------- 456 
118579112  496 --LvkdpdfyqkelftglalsqqtvalTeaieggvfeenrrvievlrrnrmifedlyapvvltspKNDILEIVRYLIDLK 573 
83319487   433 --YkdselktdttcligltnssneefiT-------------------------------------VADILSTVSYLLNLK 473 
42561522   433 --YkdselktdttcligltsssneefiT-------------------------------------VADILSTVSYLLNLK 473 
13357745   508 qtL------------------------T-------------------------------------VADLVATTSYIYNLN 526 
170761945  508 qtL------------------------T-------------------------------------VADLVATTSYIYNLN 526 
162447041  447 ifV------------------------A-------------------------------------VSDIVASISYFLNLY 465 
39938746   453 --I------------------------T-------------------------------------LSDVIASINYYLNLY 469 
197294699  453 --I------------------------T-------------------------------------LSDIIASISYYLNLY 469 
85057741   453 --I------------------------T-------------------------------------LSDVIASINYYLNLY 469 
50365415   457 --I------------------------T-------------------------------------VVDIVATVSYLLGLE 473 
118579112  574 NGRGAIDDIDHLGNRRVRAVGELLENQYRIGLVRMERAIKERMSLQE--VEN---------------------------- 623 
83319487   474 YNIGEIDDIDNLGNRRVRTVGELLQNQFRMGLNRIDKNVKEKLATSD--LYK---------------------------- 523 
42561522   474 YNIGEIDDIDNLGNRRVRTVGELLQNQFRMGLNRIDKNVKEKLATSD--LYK---------------------------- 523 
13357745   527 YEIGEFDDIDHLGNKRLKLIHELLRARIATSMARIEKFINEKLAISDgsSNNitnvndkgidteldreieesdmsdeekk 606 
170761945  527 YEIGEFDDIDHLGNKRLKLIHELLRARIATSMARIEKFINEKLAISDgsSNNitnvndkgidteldreieesdmsdeekk 606 
162447041  466 DGLGNVDDIDHLGNRRLRLIGELLKNQFRIGLARAEKNIKDKMSTTN--FND---------------------------- 515 
39938746   470 ENVGTVDDIDHLGNRRLRLIGELLKNQFRIGLTRAEKNIKDMISTSK--FSE---------------------------- 519 
197294699  470 EGIGNVDDIDHLGNRRLRLIGELLKNQFRIGLTRAEKHIKDMISVSK--FSE---------------------------- 519 
85057741   470 ENVGTVDDIDHLGNRRLRLIGELLKNQFRIGLTRAEKNIKDMISTSK--FGE---------------------------- 519 
50365415   474 YNIGEYDDIDNLANRRVRTVGELLQNQFRMGLTRIDKNVKEKLSTSD--LYK---------------------------- 523 
118579112  624 --L-MPHDLINSKPVSAVVKEFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRVCPIET 700 
83319487   524 --V-KTSTIINAKPLTAIIGEFFNLSQLSQFMDQINPLSELTNKRRLTALGPGGLSRDRAGLEVRDVHPSHYGRICPIET 600 
42561522   524 --V-KTSTIINAKPLTAIIGEFFNLSQLSQFMDQINPLSELTNKRRLTALGSGGLSRDRAGLEVRDVHPSHYGRICPIET 600 
13357745   607 kaI-SVKSIINTKQFQSLVKDFFNSHQLIQFIDQQNPLAELTNKRRISAMGPGGISREDPNLDIRDVHHSHSSRICPIET 685 
170761945  607 kaI-SVKSIINTKQFQSLVKDFFNSHQLIQFIDQQNPLAELTNKRRISAMGPGGISREDPNLDIRDVHHSHYSRICPIET 685 
162447041  516 --A-TPANVINMTPLVGAIKTFFGSSQLSQFMDQINPLAELTQKRRVSALGTGGIARDRAGVEVRDVHNSHYGRLCPIET 592 
39938746   520 --VnGPGDLVNFTFLMSVIKTFFTSSRLSQFMDQINPLAELTQKRRVSALGIGGINRDRAGIEVRDVHNSHYGRLCPIET 597 
197294699  520 --V-GPGELVNFGFLNGVIKTFFANSRLSQFMDQINPLAELTQKRRVSALGVGGINRDRAGVEVRDVHNSHYGRLCPIET 596 
85057741   520 --VnGPGDLVNFTFLMSVIKTFFTNSRLSQFMDQINPLAELTQKRRVSALGIGGINRDRAGIEVRDVHNSHYGRLCPIET 597 
50365415   524 --V-KVSTIINAKPLTAVIGEFFNLSQLSQFMDQINPLAELTNKRRLTALGPGGLSRDRASLEVRDVHPSHYGRICPIET 600 
118579112  701 PEGPNIGLIASLSTYARINDHGFVETPYRIVLD----GKL-TNEVRFFSALEEEGHAIAQANAEVDAEGRFVNDYVSARK 775 
83319487   601 PEGPNIGLINNLSTYARVNEYGFITTPYRKVIN----GIIqNDQVEYLTADQEKNFIIAQSNVNQDENGKILDEIIVSRF 676 
42561522   601 PEGPNIGLINNLSTYARVNEYGFITTPYRKVIN----GIIqNDQVEYLTADQEKNFIIAQSNVNQDENGKILDEIIVSRF 676 
13357745   686 PEGMNIGLIMSLASLAKVDENGFIVAPYYVVED----GVV-KEDYKYLTAHEDDNYIIAESSVQLDENKRILDEQVVARY 760 
170761945  686 PEGMNIGLIMSLASLAKVDENGFIVAPYYVVED----GVV-KEDYKYLTAHEDDNYIIAESSVQLDENKRILDEQVVARY 760 
162447041  593 PEGPSIGLISSLATYAKVDEYGFIKTPFLKVVQngneTSV-TKEVIYLTADEESDHVIASAATPMDEHGLFIESRVIARR 671 
39938746   598 PEGPSIGLITSLSTYAKVNKYGFIQTPFFKVLHqdgkTTL-SRHIDYLTADQEKEEIIASAGFVLDANNAFKDKKIIARS 676 
197294699  597 PEGPSIGLIASLAIYAKVDDYGFIQTPFFKVFVqngaSYV-SNQIEYLTADQEKEEIIASSGYELNSDATFQKDKVIARK 675 
85057741   598 PEGPSIGLITSLSTYAKVNKYGFIQTPFFKVLQqdgkTTL-SRDIDYLTADQEKEEIIASAGFVLDANNSFQDKKIIARS 676 
50365415   601 PEGPNIGLINNLSTYAIVDELGFIRTPYLKVID----GVI-QNEHEYLSADEEKEYIISQSNVTKDENGKILDETVVSHY 675 
118579112  776 SGEFILVHRDEIELMDVAPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLLRADSPLVGTGMERIVAKDSGVSVIA 855 
83319487   677 NGDDYMAKVEEIHYIDVSPKQIVSVATSGIPFLENDDANRALMGANMQRQAVPLIKPESPIVATGIEFEAARDSGEAIVA 756 
42561522   677 NGDDYMAKVEEIDYIDVSPKQIVSVATSGIPFLENDDANRALMGANMQRQAVPLIKPESPIVATGIEFEAARDSGEAIVA 756 
13357745   761 RGSTGLFSPNEVDFIDIVPKQVVSIAASAIPFIENDDGARALMGSNMQRQATPLIKPYAPIVGTGTEFKIAHDSGMAVVA 840 
170761945  761 RGSTGLFSPNEVDFIDIVPKQVVSIAASAIPFIENDDGARALMGSNMQRQATPLIKPYAPIVGTGTEFKIAHDSGMAVVA 840 
162447041  672 NGETGIYDANEITAMDVSPKQVVSVATSSIPFLEHDDASRALMGANMQRQAVPLLQPTSPIVGTGVEYRAAKDSGAVVIA 751 
39938746   677 NGETGIFERSQITYADVSPKQIVSVATSSIPFLEHNDASRALMGANMQRQAVPLLIPESPIVGTGVEYRAAKDSGCLIIA 756 
197294699  676 NGEIGIYPKEQVTYADISPKQIVSIATASIPFLEHNDSSRALMGSNMQRQAVPLLVTESPIVGTGIEYRAAKDSGSLIIA 755 
85057741   677 NGETGIFERNQITYADVSPKQIVSVATSSIPFLEHNDASRALMGANMQRQAVPLLIPESPIVGTGVEYRAAKDSGCLIIA 756 
50365415   676 KGDDYIAKVSEVQFIDVSPKQIVSVATSAIPFLENDDANRALMGANMQRQAVPTIVPESPFVGTGIEFEAARDSGVCIVA 755 
118579112  856 RHNGVVESVDASRIVVKIdeSEVDETGTGV---------------------------DIYNLIKFARSNQNTCINNKPVV 908 
83319487   757 KEDAIVKYVDSKTIITDG--------ESGI---------------------------RTYILSDYERSNNGTSLTQSPIV 801 
42561522   757 KEDAIVKYVDSKTIITDG--------ESGI---------------------------RTYILSDYERSNNGTSLTQSPIV 801 
13357745   841 KNDGVVEFVDSQKIIIRN-------DNDKL---------------------------DDYKLIKYRKSNQDTCNNQIPIV 886 
170761945  841 KNDGVVEFVDSQKIIIRN-------DNDKL---------------------------DDYKLIKYRKSNQDTCNNQIPIV 886 
162447041  752 KNSGYVTYVDGKKIIITP--EPTDTIKSGSktlykvggefdyg-iakklyetksvqnDQYDLVQFFRSNQDTLILQKPIV 828 
39938746   757 RESGFVTYVDAQKIIITK--KPNQNVSLNGktlydttqeftyaqakalyennykehqAEYTLINFAKSNQDTLVLQKPIV 834 
197294699  756 SQPGIVTYVDAKKIVTSD--------QEGNk--------------------------KEYQLTTFEKSNQDTLILQKPIV 801 
85057741   757 RESGFVTYVDAQKIIITK--KPNQTVSLNGktlydttqeftytqakvlyennhkeyqAEYTLINFAKSNQDTLVLQKPIV 834 
50365415   756 TENGIVKYVDAKQITVES--------KAGI---------------------------KTYTLANFERSNNGSSIVQKPIV 800 
118579112  909 KVGDVVKRHDVIADGPSTDMGELALGQNIVVAFMPWGGYNFEDSILVSEKLVKDDRYTSIHIEEYECVARDTKL--GKEE 986 
83319487   802 KVGDVVKKGEIIADGPSMDQGELAIGQNVVVAFSTYNGYNFEDAIVMSERIVIDDRFTSIHIDEYTLEVRNTKQ--GQEE 879 
42561522   802 KVGDVVKKGEIIADGPSMDQGELAIGQNVVVAFSTYNGYNFEDAIVMSERIVIDDRFTSTHIDEYTLEVRNTKQ--GQEE 879 
13357745   887 KVGQRVHKSETIGDGPAMQNGELALGRNILVGYTTWRGYNFEDAIIISERLVDQDVFTSIHIDEHTIQCMKTKN--GDEE 964 
170761945  887 KVGQRVHKSETIGDGPAMQNGELALGRNILVGYTTWRGYNFEDAIIISERLVDQDVFTSIHIDEHTIQCMKTKN--GDEE 964 
162447041  829 MQGEYVDAGDVIADGPSTENGELALGRNVTVAFMTWEGYNYEDAVIMSEDLVKHDVYTSIHIDEYEIETRDLKQanGKEE 908 
39938746   835 VLGEQINEGDILVSGPSTSQGELALGRNVTVAFMTWEGYNYEDAIIMSEELVKHDVYTSIHIDKYEVQTRELKKgsGQEE 914 
197294699  802 SLGDNIQKGDILVDGPSTNQGELALGRNILVAFMTWEGYNYEDAIIISEELVKNDVYTSVHINKYSVQTRELKKgsGKEE 881 
85057741   835 VLGEHINEGDILVSGPSTSQGELALGRNVTVAFMTWEGYNYEDAIIMSEELVKHDVYTSIHIDKYEVQTRELKKgsGQEE 914 
50365415   801 KVGDSIEAGQIIADGPSVDNGELALGQNVVVAFTTYNGYNFEDAIVMSERVIMEDKFTSVHIDEYVLEVRNTKQ--GAEE 878 
118579112  987 ITSDIPNLGEEALKDLDESGIIRIGAEVKPGDILVGKITPKGETQLSPEEKLLRAIFGEKAGDVRDTSLTVPPGVEGTVI 1066
83319487   880 VTREIPNMSEQAKRHLDAEGIVAIGTEVKVGDVLVGKVTPKGQVQLSPEDKLLHAIFGEKSRNVKDNSLRVPNGGEGIVQ 959 
42561522   880 VIREIPNMSEQAKRHLDAEGIVAIGTEVKVGDVLVGKVTPKGQVQLSPEDKLLHAIFGEKSRNVKDNSLRVPNGGEGIVQ 959 
13357745   965 ITRDMPNVSDTAKRFLDNQGIVLVGAEVHEGDVLVGKTTPRGNVETAPEDRLLQTIFGDKSKTVKDSSLKVKHGQEGIVA 1044
170761945  965 ITRDMPNVSDTAKRFLDNQGIVLVGAEVHEGDVLVGKTTPRGNVETAPEDRLLQTIFGDKSKTVKDSSLKVKHGQEGIVA 1044
162447041  909 ITREIPNVGQEAIKFLDERGIIVPGSEVKEGDILVGKITPKGVFEPTPSEKLIHAVIGDKAKEYRDSSLRVPHGGGGVVQ 988 
39938746   915 ITREVPNVGADAIKNLDERGIIIPGSEVKEGDILVGKITPQGNIEPSPSEKLIQIVIGEKAREYKDSSLRVPFGEGGIVQ 994 
197294699  882 ITREVPNVGADAIKNLDERGIIIPGSEVKEGDILVGKITPQGNVDPTPQEKLIQIVIGEKAREYKDSSLRVPYGEGGIVQ 961 
85057741   915 ITREVPNVGADAIKNLDERGIIIPGSEVKEGDILVGKITPQGNIEPSPSEKLIQIVIGEKAREYKDSSLRVPFGEGGIVQ 994 
50365415   879 ITSEIPNISDNAKKYLDNEGIVAIGTEVKTGDILVGKVTPKGQTQLSPEDKLLHAIFGEKSRSVKDNSLKVPNGGEGIVQ 958 
118579112 1067 GAKVFSRkgadkdtrteliekaeeeklrkdeqdeiriirqsaegklhrlligkslsvkledgegnlilakgkeitaealk 1146
83319487   960 SIKRFKAks----------------------------------------------------------------------- 968 
42561522   960 SIKRFKAks----------------------------------------------------------------------- 968 
13357745  1045 AVKRIKSs------------------------------------------------------------------------ 1052
170761945 1045 AVKRIKSs------------------------------------------------------------------------ 1052
162447041  989 SVQYFSK------------------------------------------------------------------------- 995 
39938746   995 SVHYFSR------------------------------------------------------------------------- 1001
197294699  962 SVQYFSR------------------------------------------------------------------------- 968 
85057741   995 SVHYFSR------------------------------------------------------------------------- 1001
50365415   959 SVKRFKAks----------------------------------------------------------------------- 967 
118579112 1147 slsindmgaisvsddgqtddnvskvidtlnrqieliqsvfedkiqkLRRGDDLPPGVIKMVKVYIAIKRKLQVGDKMAGR 1226
83319487   969 --------------------------------------------alNPDGIELPADIIEVIKVYVVQKRKIQEGDKMSGR 1004
42561522   969 --------------------------------------------alNPDGIELPADIIEVIKVYVVQKRKIQEGDKMSGR 1004
13357745  1053 ----------------------------------------------DENGSELPDDVIEIIKVYIVQKRKIQVGDKMAGR 1086
170761945 1053 ----------------------------------------------dENGSELPDDVIEIIKVYIVQKRKIQVGDKMAGR 1086
162447041  996 -----------------------------------------------KNGDQLPTGVNEQIRVYIAKKRKITEGDKMAGR 1028
39938746  1002 -----------------------------------------------KNGDVLPAGVNENIRVFIAKKRKINEGDKMAGR 1034
197294699  969 -----------------------------------------------KNGDILPPGVNENIRVFIAKKRKISEGDKMAGR 1001
85057741  1002 -----------------------------------------------KNGDVLPAGVNENIRVFIAKKRKINEGDKMAGR 1034
50365415   968 --------------------------------------------aaNPDGIDLPADVLEVIKVYIVQKRKIQEGDKMSGR 1003
118579112 1227 HGNKGVVSRILPEEDMPYMEDGRPVEIVLNPLGVPSRMNVGQILETHLGWAAKGIGWRieemlqkqtsaeslkaylkdvy 1306
83319487  1005 HGNKGIISRILPIEDMPHLEDGTPVDIILNPQGVPSRMNIGQILEIHLGMAAKKLNQK---------------------- 1062
42561522  1005 HGNKGIISRILPVEDMPHLEDGTPVDIILNPQGVPSRMNIGQILEIHLGMAAKKLNQK---------------------- 1062
13357745  1087 HGNKGIVSKVVPIQDMPFLKDGTPLDIMLNPLGVPSRMNIGQILELHLGYAAAEIGKKqliqiaidqlgyekyislfgin 1166
170761945 1087 HGNKGIVSKVVPIQDMPFLKDGTPLDIMLNPLGVPSRMNIGQILELHLGYAAAEIGKKqliqiaidqlgyekyislfgin 1166
162447041 1029 HGNKGVISKILPREDMPYLADGTYVDIMLNPLGVPSRMNIGQILEIHLGISAQKLGIK---------------------- 1086
39938746  1035 HGNKGVISRILPKEDLPYMADGTPIDIMLNPLGVPSRMNIGQILEIHLGMAAKKLGIK---------------------- 1092
197294699 1002 HGNKGVISRILPKEDLPFMEDGTTIDVMLNPLGVPSRMNIGQILEIHLGMSAKNLNIK---------------------- 1059
85057741  1035 HGNKGVISRILPKEDLPYMADGTPIDIMLNPLGVPSRMNIGQILEIHLGMAAKKLGIK---------------------- 1092
50365415  1004 HGNKGIISKVLPVEDMPHLEDGTPVDILLNPQGIPSRMNIGQILEIHLGMAAKKLGVK---------------------- 1061
118579112 1307 gdde-------------------vgtfidgmdqeelmlvcrrlqrgvsMASPVFEGASEDKIKSMLGKAGFH---SSGQV 1364
83319487  1063 ------------------------------------------------VITPVFEGLNEKELEEIMAEAGMT---NYGKV 1091
42561522  1063 ------------------------------------------------VITPAFEGLNEKELEEIMAEAGMT---NYGKV 1091
13357745  1167 eiiakklyenisnlikhkqakqakdidlidvtiilkelglsyddigikISTPVFDGANHDDIVSIMNEANIDienNKGKQ 1246
170761945 1167 eiiakklyenisnlikhkqakqakdidlidvtiilkelglsyddigikISTPVFDGANHDDIVSIMNEANIDienNKGKQ 1246
162447041 1087 ------------------------------------------------VASPVFDGVTNDELGAIMEEAGIA---PDGKT 1115
39938746  1093 ------------------------------------------------VATPVFDGVNDYDLKEIMKEANLD---PDGKM 1121
197294699 1060 ------------------------------------------------VATPVFDGVNDQDLKEISQEANLE---LDGKK 1088
85057741  1093 ------------------------------------------------VATPVFDGVNDYDLKEIMKEANLE---PDGKM 1121
50365415  1062 ------------------------------------------------IATPVFEGVNSNDLDEIMAEAGME---NYGKV 1090
118579112 1365 TLFDGRSGDPFKHKVTVGVMYVLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRLGEMEVWAMEAYGAAYALQEF 1444
83319487  1092 TLIDGQTGEPFDKPIAVGVMYMLKLSHMVDDKIHARNVGPYSLITQQPLGGKAQNGGQRFGEMEVWALEAYGAAHTLREI 1171
42561522  1092 TLIDGQTGEPFDKPIAVGVMYMLKLSHMVDDKIHARNVGPYSLITQQPLGGKAQNGGQRFGEMEVWALEAYGAAHTLREI 1171
13357745  1247 VLYDGRTGEPFDGLISVGLTYMLKLDHMVDDKIHSRSVGPYSKITQQPLGGKSQNGGQRFGEMEVWALEAYGAAYNLLEI 1326
170761945 1247 VLYDGRTGEPFDGLISVGLTYMLKLDHMVDDKIHSRSVGPYSKITQQPLGGKSQNGGQRFGEMEVWALEAYGAAYNLLEI 1326
162447041 1116 TLYDGRTGEPYNNRISVGVMYMIKLSHMVDDKLHARNVGPYTLVTQQPMGGKAQNGGQRFGEMEVWALYAYGAAHTLQEM 1195
39938746  1122 VLYDGRTGEPYDSRISVGVMYMVKLSHMVDDKLHARNVGPYTLVTQQPMGGKVQNGGQRFGEMEVWALYAYGAAHTLQEI 1201
197294699 1089 VLYDGRTGEPYENRISVGVMYMIKLSHMVDDKLHARNVGPYTLVTQQPMRGKIREGGQRYGEMENWAVHAHGAAYTLQEF 1168
85057741  1122 VLYDGRTGEPYDSRISVGVMYMVKLSHMVDDKLHARNVGPYTLVTQQPMGGKVQNGGQRFGEMEVWALYAYGAAHTLQEI 1201
50365415  1091 KLIDGQTGEAIDKPISVGVMYMLKLSHMVDDKLHARSVGPYSLITQQPLGGKAQNGGQRFGEMEVWALEAYGAAHTLREI 1170
118579112 1445 LTVKSDDVSGRTRMYEAIVKGKHTLEPGLPESFNVLIKELQSLCLDVELLEG----------------------EDE 1499
83319487  1172 LTIKSDDIKGRSKTYEAIVRSKRIPEPGIPESFNVLSKEIMGLGFNMYMIDEtgeksainaydkkdfeidnyddEIL 1248
42561522  1172 LTIKSDDIKGRSKTYEAIVRSKKIPEPGIPESFNVLSKEIMGLGFNMYMIDEtgeksvinaydkknfdadnyedDEI 1248
13357745  1327 LTIKSDDVQGRNQAYNAIIKGHDVVADGMPESFKLLTKQMQGLGLCITVETKddrmvdiney--tlnqnrlnndDDE 1401
170761945 1327 LTIKSDDVQGRNQAYNAIIKGHDVVADGMPESFKLLTKQMQGLGLCITVETKddrmvdiney--tlnqnrlnndDDE 1401
162447041 1196 LTIKSDDMIGRNKVYYAITHGQEIPKASIPESFRVLTRELQALGLYVELIDAnkgeneaikslvdnsskgfnkgrf- 1271
39938746  1202 LTVKSDDIVGRNKTYSAIVQGTPLPKPSIPESFRVFIKELQSLGLYVELIKTdtkenevnkslidykkegyn----- 1273
197294699 1169 LTIKSDDIIGRNQTYSAIVQGKQLPKPNIPESFRVLIKELQALGLYVELIKTdtkenevnkslidykkegyn----- 1240
85057741  1202 LTVKSDDIVGRNKTYSAIVQGTQLPKPSIPESFRVFIKELQSLGLYVELIKTd---------------------TKE 1257
50365415  1171 LTIKSDDLKGRTKTYEAIVRSKNIPTPGTPESFNVLSKEIMGLGFDIYLLDNk---------------------GNK 1226
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