1XDO


Conserved Protein Domain Family
poly_P_kin

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TIGR03705: poly_P_kin 
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polyphosphate kinase 1
Members of this protein family are the enzyme polyphosphate kinase 1 (PPK1). This family is found in many prokaryotes and also in Dictyostelium. Sequences in the seed alignment were taken from prokaryotic consecutive two-gene pairs in which the other gene encodes an exopolyphosphatase. It synthesizes polyphosphate from the terminal phosphate of ATP but not GTP, in contrast to PPK2. [Central intermediary metabolism, Phosphorus compounds]
Statistics
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PSSM-Id: 274734
Aligned: 41 rows
Threshold Bit Score: 915.759
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1XDO_A         6 YIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFAELKRRIIISEEQGSNS---HSRHLLGKIQSR 82  Escherichia coli
KGH43777       9 YTNRELSWLDFNYRVLDEARDKDNPLLERVRFLGITQSNLDEFFTVRVASLRKLMSVNYTKPDPAg-lTAADQVSAISDK 87  Lactobacillus p...
WP_011679151  10 YVNREMSWLAFNKRVLEEGRDTQNPILERANFLAITQKNMDEWFMVRVASLQQQMFVGHDKVDASg-lSPKQQLIKISAA 88  Leuconostoc mes...
WP_011217483   7 YIEKELSWLSFNERVLQEAADKSVPLIERVRFLGIFSSNTDEFYKVRFADIKRRILINQVQGGDD---VAKHLLSKIQSR 83  Photobacterium ...
WP_011706631   7 YEEKELSWLSFNERVLQEAMDKTVPLIERVRFLGIFSSNQDEFFKVRVSDVKRRILINEVHGGDD---EAKVLLRAIQQK 83  Aeromonas hydro...
WP_001271572   7 YIDKELSWLSFNERVLQEAADKTVPLIERIRFLGIFSNNLDEFYKVRFADVKRQILINRERGGND---ISKHLLSRMQSK 83  Vibrio cholerae
WP_000245004   9 YIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFAELKRRIIISEEQGSNS---HSRHLLGKIQSR 85  Escherichia coli
WP_011626401   9 SIDKEISWLSFNERVLQEACDPNVPIVERVRFLGIFSNNMDEFFRVRVAAVRRSILLSALQEGRSn---SRHLMAKIQTK 85  Shewanella sp. ...
WP_011576058   8 YFSREISWLAFNQRVLQEAADRKNPIVERIRFLGIYSSNMDEFYRVRVADVKRKIYIHLDEGDNEkaeQTKILMEQIQEK 87  Pseudoalteromon...
WP_011107315  12 YVERDISWMYFNQRILLEAARPEVPLLERLTFLGIYSNNLDEFFRVRVATLNRIIEYADKNIQKEq-eTATRTLKQISKL 90  Bacteroides
1XDO_A        83 VLKADQEFDGLYNE-LLLEMARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILI-NPDTdLVQFLKDDYTYLAVEI 160 Escherichia coli
KGH43777      88 AHEMVKRQYNTLNRsLLPLLEQHAIHLLSMADLNEEQHAFVKNYFDDELYPALTPMAD-DSSR-PFPFIGNNTLNIALRI 165 Lactobacillus p...
WP_011679151  89 AGEQIKNQYQVLNRsIIPTMKKLGFSLVHKNDLTNAQVNFLKKFFEKELRPVLTPMAI-DSTR-PFPFLANDTLNIGVRL 166 Leuconostoc mes...
WP_011217483  84 VLKMNQDFDTLYNE-ILLEMARRHIFLVNDLQLDVNQQNWLRRYFHDSILPHITPILLtDDIE-LLQFLKDEYSYLAIEM 161 Photobacterium ...
WP_011706631  84 VMALGEAFDNTYKE-LLIALARHNIFLVNEYQLSESIQQWLRVFFKEKVLRHIIPILL-NKEVnPVKFLKDEYTYLAIEM 161 Aeromonas hydro...
WP_001271572  84 ALKLNQDFDNLYNE-LILEMARRRIFLVNETQLDEIQLKWVKKYFHKEVLPHVTPIML-RDDIdVMQFLKDEYAYIAVEM 161 Vibrio cholerae
WP_000245004  86 VLKADQEFDGLYNE-LLLEMARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILI-NPDTdLVQFLKDDYTYLAVEI 163 Escherichia coli
WP_011626401  86 VMALQERFDSIYVE-LMRELVRRNILLINEKQLSEFHSNWLKKHFRDHFKRHIAPLIV-NNNRdLVKHINDDATYLCVCL 163 Shewanella sp. ...
WP_011576058  88 VLGMTEDFERVRED-VVARLARYNIFLLENEKLSDYQTTWLKNYFKNKILRHIAPILL-HGKVnLVSRLNDSATYLYVAI 165 Pseudoalteromon...
WP_011107315  91 HNRFYEQFEETFAS-IMEELKKENICVIKDTEMTDDQKTFITSFYRNKLNGSTTPLFL-NGAR-PLDDQTDEDIYLAIRL 167 Bacteroides
1XDO_A       161 IR----GDT--IRYALLEIP-SdKVPRFVNLPPEAP-R-RrK-PMILLDNILRYCLDDIFKGffdY---DALNAYSMKMT 227 Escherichia coli
KGH43777     166 YKng-dKKD--RKFATVQVP-D-VFPRVVVLPGAP------N-QFILIEEIIKAFVGSLFIN---Y---TVKETSCYRVM 227 Lactobacillus p...
WP_011679151 167 KKnd-eKSE--KYIAVLQVP-E-TSGRVIALPEE-------N-QVILVEDVVQLFLDALFPG---Y---TIKESNVFHIL 227 Leuconostoc mes...
WP_011217483 162 QQ----GEK--KRHALIEIPtD-QLPRFIELPEPKG-K-R-KkTLILLDNIIRFCLDDIFNGffeY---DSLAAYSMKMT 228 Photobacterium ...
WP_011706631 162 KKn---GQV--IQYALVEVPtD-DLPRFFQLPPEGT-R-R-KkQIIILDNVIRFCLDEIFKGffdY---DEIAAYAVKLT 229 Aeromonas hydro...
WP_001271572 162 r----sGDE--FKYALIEIPtD-QLPRFVMLPEQKG-K-RrK-TIILLDNIIRLCLDEIFRGfydY---DTLNGYAMKMT 228 Vibrio cholerae
WP_000245004 164 IR----GDT--IRYALLEIPsD-KVPRFVNLPPEAP-R-RrK-PMILLDNILRYCLDDIFKGffdY---DALNAYSMKMT 230 Escherichia coli
WP_011626401 164 FTks------rRQYALVEVPtK-NVPRFIELPAEKS-KaK-K-YLILLDNIIRHCVDDLFGPffeY---EAIEVYSMKLT 230 Shewanella sp. ...
WP_011576058 166 nn---sGKN--TQYATIEVP-SkALSRFVVIPPENSrK-K-K-YIILLDDIIRLNLESIFKG---FvdfESGEAYSFKMT 233 Pseudoalteromon...
WP_011107315 168 LRkdetGKIkeKDYAVIELPtE-EYGRFIQLPDSEG-K---T-YLMFLDDVIRYCLPLIFVGm-kY---TDYEAYTFKFT 237 Bacteroides
1XDO_A       228 RDAEYDL-VHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVLREKLTISRYDSIVPGGRYhNFKDFINFPN-V 305 Escherichia coli
KGH43777     228 RDLDLDV-AEEDTSDLLKEVQKQLKMRERGKVMRLEVEKSMSKHQRTRLAKALGINESALYVINGPL-NLTFLSKLVKaV 305 Lactobacillus p...
WP_011679151 228 RDMELDVaDDEDTPNILQEVQSKLQERERGRVIRVIVSANTGKMLMTQLIKALQVPDDRIYEVSGPI-DLTFISSWLKvI 306 Leuconostoc mes...
WP_011217483 229 RDAEYDL-SQEVEHSLLEQMSEGLNQRITAMPVRFVYQRDMPGNMIDVLCGLLKVSRYDSIIPGGRYhNFKDFIGFPN-V 306 Photobacterium ...
WP_011706631 230 RDAEYDL-SDQLDLSLVDKMSDGLKQRLTAMPVRFVYEREMPAAMISFLKLKLQISSYDAIMPGGRYhNFKDFIGFPN-V 307 Aeromonas hydro...
WP_001271572 229 RDAEYDL-RHEVEYSLLEQMSEGLSQRLTALPVRFVYEREMPEAMLKFLCYKLKISHYDSLIPGGRYhNFKDFISFPN-V 306 Vibrio cholerae
WP_000245004 231 RDAEYDL-VHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVLREKLTISRYDSIVPGGRYhNFKDFINFPN-V 308 Escherichia coli
WP_011626401 231 RDAEFDI-TDELEQTQLEKMTKGLKKRLTAEPVRLVYDKEMPEHMLEMLKENLNISSTECLIPGGRYhSFKDFIGFPNp- 308 Shewanella sp. ...
WP_011576058 234 RDSEYSI-NDEIEESYVEKMSESMKQRLIAEPVRVVYDEQMPSDMVRNLKKRLKISSYDSLIAGGTYrNFKDFIGFPN-V 311 Pseudoalteromon...
WP_011107315 238 KDAEMEI-DSDLRTGVLQKISKGVKSRKRGEPIRFVYDEQIPKDLLKRLVDRLNVDKNDTRVAGGRYhNFKDLMKFPV-C 315 Bacteroides
1XDO_A       306 -GKANLVNKPLPRLRHIWFDkaQFRNGFDAIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDS 384 Escherichia coli
KGH43777     306 qGHEDLNYPKYHAYYPAKYR--E-RSIFDLIKDHDILMQYPYDDFKPVVDFIHEAAEDEDVLAIKMTLYRVSADSPIIKY 382 Lactobacillus p...
WP_011679151 307 -DAPTLEYTSFHGYENPDLT---ADKIFESIRKRDYLLHHPYDSFKPVVQFIQTAAIDDDVLAIKMTLYRVSGNSPIIKA 382 Leuconostoc mes...
WP_011217483 307 -GRKYLENASLPPIQSYHFT--QARNAFDAIKAQDILLYYPYHTFNHVTEFIRQASYDPKVRSIKINIYRVAKHSRVIDS 383 Photobacterium ...
WP_011706631 308 -GRDYLENPKLPALDCRDFD--GFVNAFDAITKQDILLYYPYHKFHHFTELVRQAAFDPAVSAIRINIYRVAKKSRIIHS 384 Aeromonas hydro...
WP_001271572 307 -GRDYLENKPLPPMTCADFE--GYANAFDAIRAQDILLHYPYHSFEHMTELVRQASFDPKVVSIKINIYRVAKDSKLMNS 383 Vibrio cholerae
WP_000245004 309 -GKANLVNKPLPRLRHIWFDkaQFRNGFDAIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDS 387 Escherichia coli
WP_011626401 309 -SRDYLENEKLPALNSSGFG--RSANSFDAIKMGDIMVNYPYHKFSHFTEMVRQAAYDPAVRFIRINLYRVAKKSHVMQS 385 Shewanella sp. ...
WP_011576058 312 -GRDYLENPKLPAITSSDFA--RHNTVFDAISEKDILLYYPYHRFLHVTEFVRQAAFDPKVKQIKLNIYRVAKNSRIIDS 388 Pseudoalteromon...
WP_011107315 316 -GRYDLKYPVWEPVFKPELN--GKESLLTLIRQKDRSLHYPFHSFDTFIRVLREAAISKEVKSIKMTLYRLAKESKVIKA 392 Bacteroides
1XDO_A       385 MIHAAHNGKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVVRYAHIGTGNFNEKTA 464 Escherichia coli
KGH43777     383 LGQAAQNGKQVTVLVEVKARFDEENNVHWAKKLEEMGCHVIYGLIGLKTHCKLALVVRRENEGIKRYMHMGTGNYNDVTA 462 Lactobacillus p...
WP_011679151 383 LSDAAQRGKQVTVLLEIKARFDEENNVHWARELEQKGVHVVYGLRGLKVHAKMAMVVRRESDTIRRYVHLATGNYNDVTA 462 Leuconostoc mes...
WP_011217483 384 MIDAANNGKRVTVVVELQARFDEEANIEWARRLTEAGVHVVFGVPGLKIHSKLCLITRQEDDKLVRYAHIGTGNFNEKTA 463 Photobacterium ...
WP_011706631 385 LIDAANNGKKVTVVVELRARFDEAANIDWANILTDAGVKVVFGVPSLKIHSKLCLITRHEQGEAVRYAHIGTGNFNEKTA 464 Aeromonas hydro...
WP_001271572 384 LVDAVHNGKRVVVVVELQARFDEEANIEWSRILTDAGVHVIFGVPGMKIHAKLLLITRKEGDEFVRYAHIGTGNFHERTA 463 Vibrio cholerae
WP_000245004 388 MIHAAHNGKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVVRYAHIGTGNFNEKTA 467 Escherichia coli
WP_011626401 386 LIDAVKNGKQVTAVIELRARFDEQSNIEWTRVLAEAGVKVHHGITSLKVHSKLCLIGREEQGEMKLYCHVGSGNFNEGTA 465 Shewanella sp. ...
WP_011576058 389 LIDAVDNGKKVTVVVELRARFDEEANIGWSKTMTDAGIKVVFGMHALKIHSKLCLVSREEKGELIHYAHFGTGNFNEKTA 468 Pseudoalteromon...
WP_011107315 393 LICAAKNGKKVTVVIELLARFDEASNINWSKRMQDAGIHVIFGVEGLKIHSKLVHIGTRHGD----IACISTGNFHEGNA 468 Bacteroides
1XDO_A       465 RLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQNSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGL 544 Escherichia coli
KGH43777     463 HFYTDMGLFTADTDMGIDASNIFNMLSGYSEPPYFHKLHISPDGIRDFINEKLDDEIAIAKAGQPAVVKMKMNSLSDPQI 542 Lactobacillus p...
WP_011679151 463 NFYTDLGLLTVDSELGADVASIFNILTGYSDPSFFHQLHMSPNGIREFIYEKINVEIKNAKAGKPSGIKMKFNSLSDERM 542 Leuconostoc mes...
WP_011217483 464 RIYTDFSLMTCNTEIADEVRQVFSYIQNPYRPVEFTHLIVSPRNSRSRLYDLIDREIAHAKQSLPSGITLKVNNLVDKGL 543 Photobacterium ...
WP_011706631 465 KIYTDFSLLTRHPDITAEVEGVFEYIEYPYRRYKFNHLLVSPINSRRQLYRLIDNELANAKAGQPSGITLKINNLVDRDL 544 Aeromonas hydro...
WP_001271572 464 RIYTDFALLTANQELAAEVRAVFGYIENPFRPVKFNHLIVSPRNSRTQIYRLLDSEIANAKAGKKAAITLKVNNLVDKGL 543 Vibrio cholerae
WP_000245004 468 RLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQNSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGL 547 Escherichia coli
WP_011626401 466 RVYTDLSLFTANQEIAREVEQVFDLIEHPYRRDNFQHLIVSPYDARQKLTHLIDNEIVNAQSHIKAAITLKLNNLLDESL 545 Shewanella sp. ...
WP_011576058 469 KIYTDFSLFTRNQELALEAENVFNFIQQPYRRQKFQHLQISPINARTKIQLLIRQEIQNVKEGLSAGITLKLNNLDDQLL 548 Pseudoalteromon...
WP_011107315 469 RMYTDYTIMTAHRPLVREVNAVFDFIEKPYTPVNFKELLVSPNDMRKRLIALISKEIKNKEQGKEAYILAKVNHITDRAL 548 Bacteroides
1XDO_A       545 VDRLYAASSSGVPVNLLVRGMCSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEVA 624 Escherichia coli
KGH43777     543 ISKLYEASHAGVKIQLIIRGICCLRTGIKGISDNIEVHSIIGRLLEHSRIYYFSNDGEPQIYLSSADMMTRNLNRRVELL 622 Lactobacillus p...
WP_011679151 543 IRHLYEASEAGVPVELIVRGITMLKVGIPKVSETIAVHSIVGRFLEHSRVFIFHNDDSPQVYLSSADLMTRNLDRRVELL 622 Leuconostoc mes...
WP_011217483 544 INMLYQASNNGVNIKLIVRGMCALIPGLKGISENITAISIVDRFLEHPRVAVFNNNNDPDVMISSADWMTRNIDNRIEVG 623 Photobacterium ...
WP_011706631 545 INRLYAAGQAGVPIQMIIRGMCALRPGVPGLSENIRVISIIDRFLEHPRVMVFHNKGNPQLYISSADWMSRNIDGRIEVG 624 Aeromonas hydro...
WP_001271572 544 INKLYGASAAGVKIRMIIRGMCSLVPGVEGVSDNIEIISIIDRFLEHPRVLVVHNDGNPQVFISSADWMERNIDHRIEVM 623 Vibrio cholerae
WP_000245004 548 VDRLYAASSSGVPVNLLVRGMCSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEVA 627 Escherichia coli
WP_011626401 546 VQKLYEASAAGVKIKLLIRGMCSLIPQIPGISDNIEIYSIVDRFLEHSRVMLFHAGGENKLFISSADWMSRNIDNRVEVS 625 Shewanella sp. ...
WP_011576058 549 IDDLYKASQAGVEVRLIIRGMCSLVPGVKGLSENISVISIVDRFLEHPRVMVFENAGEKRVFISSADWMTRNMDFRIEVG 628 Pseudoalteromon...
WP_011107315 549 IEKLYEASTAGVQVELVVRGNCSLVTGIAGISENIHINGIIDRYLEHSRIFIFANGGEEKYYIGSADWMPRNLDNRIEVL 628 Bacteroides
1XDO_A       625 TPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYvPRGNRR---KVRAQLAIYDY 679 Escherichia coli
KGH43777     623 FPLLQPEISHRAMTIFETMWADTVKTRILQPDNTYARvDGRGLE---VLDSQAEFIRE 677 Lactobacillus plantarum CMPG5300
WP_011679151 623 FPIRNAGLSQQVINIFEIMWADNVKTRVLQPDGSFDKiDRRGLS---SVNAQEMFIAE 677 Leuconostoc mesenteroides
WP_011217483 624 CLINDPALKKKIIDILNIQLTDTVKARILDKAMSNQYvPRGNRR---KIRSQIAIYDY 678 Photobacterium profundum
WP_011706631 625 TPIYDERLKQRILDILELQLSDTCKARVIDADQQNEYvKRGNRR---KIRSQVAIYDY 679 Aeromonas hydrophila
WP_001271572 624 APIRDERLKQRIIDILNIQFIDTVKARRIDKEMSNQYvERGNRR---KVRSQIAIYDY 678 Vibrio cholerae
WP_000245004 628 TPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYvPRGNRR---KVRAQLAIYDY 682 Escherichia coli
WP_011626401 626 VPIYDPRLKQMVMDILSLQFNDNTKARIINKEQSNPYrNRGNKR---KVRSQIAIYQY 680 Shewanella sp. MR-7
WP_011576058 629 CPIYEPKLIKQILDILEIQFQDTLKARIIDQHQSNKYvRRGNRK---KLRSQIETYEY 683 Pseudoalteromonas atlantica
WP_011107315 629 APVYDKEIQADLKRIVCYGYRDTAKGRIVDGTGENRPwENRPSTlckDFTPALAEAET 686 Bacteroides
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