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SARS-CoV-like_RdRp: Severe acute respiratory syndrome coronavirus RNA-dependent RNA polymerase, also known as non-structural protein 12, and similar proteins from betacoronaviruses in the B lineage: responsible for replication and transcription of the viral RNA genome
This group contains the RNA-dependent RNA polymerase (RdRp) of Severe acute respiratory syndrome cor...
View in Cn3D Specific ProteinProteinSuperfamilySuperfamily MembersPubMed
betaCoV_Nsp2_SARS-like: betacoronavirus non-structural protein 2 (Nsp2) similar to SARS-CoV Nsp2, and related proteins from betacoronaviruses in the B lineage
Non-structural proteins (Nsps) from Severe acute respiratory syndrome coronavirus (SARS-CoV) and bet...
TM_Y_SARS-CoV-like_Nsp3_C: C-terminus of non-structural protein 3, including transmembrane and Y domains, from Severe acute respiratory syndrome-related coronavirus and betacoronavirus in the B lineage
This model represents the C-terminus of non-structural protein 3 (Nsp3) from betacoronavirus in the ...
betaCoV_Nsp14: nonstructural protein 14 of betacoronavirus
Nonstructural protein 14 (Nsp14) of coronavirus (CoV) plays an important role in viral replication a...
betaCoV_Nsp13-helicase: helicase domain of betacoronavirus non-structural protein 13
This model represents the helicase domain of non-structural protein 13 (Nsp13) from betacoronavirus,...
CoV_Methyltr_2: Coronavirus 2'-O-methyltransferase
This domain covers the NSP16 region of the coronavirus polyprotein. The SARS-CoV RNA cap SAM-depende...
View in Cn3D
betaCoV_Nsp5_Mpro: betacoronavirus non-structural protein 5, also called Main protease (Mpro)
This subfamily contains the coronavirus (CoV) non-structural protein 5 (Nsp5) also called the Main p...
betaCoV_PLPro: betacoronavirus papain-like protease
This model represents the papain-like protease (PLPro) found in non-structural protein 3 (Nsp3) of b...
cv_Nsp4_TM: coronavirus non-structural protein 4 (Nsp4) transmembrane domain
Nsp4 may be involved in coronavirus-induced membrane remodeling. In order to assemble the replicatio...
betaCoV-Nsp6: betacoronavirus non-structural protein 6
Coronaviruses (CoV) redirect and rearrange host cell membranes as part of the viral genome replicati...
CoV_NSP8: Coronavirus replicase NSP8
Viral NSP8 (non structural protein 8) forms a hexadecameric supercomplex with NSP7 that adopts a hol...
bCoV_NSP3_N: Betacoronavirus replicase NSP3, N-terminal
This domain family corresponds to the N-terminal domain of NSP3 (non-structural protein 3, also know...
View in Cn3D ProteinSuperfamilySuperfamily MembersPubMed
NendoU_cv_Nsp15-like: Nidoviral uridylate-specific endoribonuclease (NendoU) domain of coronavirus Nonstructural Protein 15 (Nsp15) and related proteins
Nidovirus endoribonucleases (NendoUs) are uridylate-specific endoribonucleases, which release a clea...
CoV_Nsp10: coronavirus non-structural protein 10
This model represents the non-structural protein 10 (Nsp10) of alpha-, beta-, gamma- and deltacorona...
bCoV_SUD_M: Betacoronavirus single-stranded poly(A) binding domain
This domain identifies non-structural protein NSP3, the product of ORF1a in group 2 coronavirus. It ...
SARS-CoV-like_Nsp1_N: N-terminal domain of non-structural protein 1 from Severe acute respiratory syndrome-related coronavirus and betacoronavirus in the B lineage
This model represents the N-terminal domain of non-structural protein 1 (Nsp1) from betacoronaviruse...
SARS-CoV-like_Nsp3_betaSM: betacoronavirus-specific marker of non-structural protein 3 from Severe acute respiratory syndrome-related coronavirus and betacoronavirus in the B lineage
This model represents the betacoronavirus-specific marker (betaSM), also called group 2-specific mar...
Macro_cv_SUD-N_Nsp3-like: SUD-N macrodomain (or Mac2 domain) of the SARS Unique Domain (SUD) of SARS-CoV non-structural protein 3 and related macrodomains
This subfamily includes the macrodomain referred to as SUD-N (N-terminal subdomain) of the SARS-uniq...
SARS-CoV-like_Nsp3_NAB: nucleic acid binding domain of non-structural protein 3 from Severe acute respiratory syndrome-related coronavirus and betacoronavirus in the B lineage
This model represents the nucleic acid binding (NAB) domain of non-structural protein 3 (Nsp3) from ...
ZBD_cv_Nsp13-like: Cys/His rich zinc-binding domain (CH/ZBD) of coronavirus SARS NSP13 helicase and related proteins
Helicases catalyze NTP-dependent unwinding of nucleic acid duplexes into single strands and are clas...
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