2JRF


Conserved Protein Domain Family
p25-alpha

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pfam05517: p25-alpha 
p25-alpha
This family encodes a 25 kDa protein that is phosphorylated by a Ser/Thr-Pro kinase. It has been described as a brain specific protein, but it is found in Tetrahymena thermophila.
Statistics
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PSSM-Id: 461670
Aligned: 63 rows
Threshold Bit Score: 102.727
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2JRF_A        11 EESFRKFAIHGdpKASGQEMNGKNWAKLCKDCKVADgKSVTGTDVDIVFSKVKGKSA-RVINYEEFKKALEELATKrfkG 89 
XP_001613902   2 ENAFYIYTKN------EADMDSRTFVKILKDAKLLS-KKLTAVDADLTFAKVKAKGA-KRINYDQFVEAVKHLVDK---H 70 
Q8I557         2 ENAFYVYTKN------LPDMDSRTFVKILKDAKLLN-KKFTTVDADLIFAKVKSKGA-KRINYDQFLEAVKCIVEK---N 70  Plasmodium falc...
ESS29883       5 DAVFKSFTHD------APAMDGRTFVKLCKDCKAFD-KNYTTTDADLIFTKVKAKGA-KTITFAEFEAAIDLIAEK---K 73 
XP_004035172   7 ETCFKAFTSG------KAEMDGKTFAKVTKDCHLQD-KKLTSTDVDLIFAKVKTSSAvRTITFKQFESGLSQIAAK---K 76 
Q244Y3         6 EGVFKKFTGG------KIEMDGKTFAKFAKDTGLLD-KKLTATDVDLIFAKVKGSSAiRCINIRQFEEGINQFAAK---K 75  Tetrahymena the...
Q244Y1         6 EGVFKKFTAN------KADMDGKTFAKFAKDCGLLD-KKLTATDIDLIFAKVKTSSAvRTITFAQFEKGLDQMATK---K 75  Tetrahymena the...
A0CF04         6 QQVFLQFTAN------KPEMDGKTFAKVSKDCHLLD-KKLTSTDVDLIFAKIKPTPAaRSITYAQFEKGLQMMAEK---K 75  Paramecium tetr...
Q22LY3         4 SAAFKKFTNQ------RSTMDSKTFVNTLADSGIFN-FKITTHQSEQIFEKVKNSPNlRGINYQQFETCLSLVASQ---T 73  Tetrahymena the...
CBN76132       5 EQIFLDFTSFGagQSGSSEMDSAKFVKLAKDCKLVG-KNLSTTDLDLIFTKVKDKTA-KKINFDTFVEAVELISEK---L 79 
2JRF_A        90 KSKEEAFdaICQLVAGK--EPANV-GvtkaKTGGAVDRLTDTSRYTGSHKE----RFD-ESGKGKGIAGRQDILdDSGYV 161
XP_001613902  71 KLDYDQF--VEKLCNEAssGPILY-G----TKAANVRFHDDKSTYTGVHKMggptTVDkNKTHFSDISEITDR--SECNI 141
Q8I557        71 KLNYDKF--VETLCQEAskGPILY-G----TKTENVRFFDDKSTFTGVHKQggpsIIDkNKTQFSDLSEITDR--SEYDI 141 Plasmodium falc...
ESS29883      74 KVSAQEL--AAQISSAS--GPVYS-G----TKALPNKFHDDKSLYTGVHANggpsTVD---GNVNDISQILDR--SAATV 139
XP_004035172  77 GVSVEDV--IKNITSAG--GPQFQ-G----TKADYVKFHDDKSQYTGVYANggptNVD--KDKISDISQTCNR--QAADV 143
Q244Y3        76 GISAQDL--REKVTASN--GPSYS-G----TKADAVRFHDDKSLYTGVYANggpsTIDiGSGKISDISQLCDR--TSADV 144 Tetrahymena the...
Q244Y1        76 GISLDAL--KEKVTSAG--GPTFT-G----TKADAVKFHDDKSLYTGVYANggpsTVDiGNGKISDISQLCDR--TGADV 144 Tetrahymena the...
A0CF04        76 GVGVQDV--HNQILNAG--GPHFQ-G----TKADAVKFHDDKNLYTGVHANggpsTIDkNHGGLNTI---CDR--SQADV 141 Paramecium tetr...
Q22LY3        74 GCTRQQI--EGLVLEYS---KKFT-T----KQADPSRFFYDKSTYTGVHTKggpsTLD--NNGYSQLSQLCDR--SSANV 139 Tetrahymena the...
CBN76132      80 GKSKDDV--ILLIVSAK--GPTTGaA----TVADNVRFHDDKSTFTGVHNNggptNID---GHNVDMANQLDRS-EGADV 147
2JRF_A       162 SAYKN 166
XP_001613902 142 RGVNL 146
Q8I557       142 RGVKM 146 Plasmodium falciparum 3D7
ESS29883     140 RGTKM 144
XP_004035172 144 RGTLK 148
Q244Y3       145 RGVKH 149 Tetrahymena thermophila SB210
Q244Y1       145 RGVKK 149 Tetrahymena thermophila SB210
A0CF04       142 RGSQK 146 Paramecium tetraurelia
Q22LY3       140 RGIKN 144 Tetrahymena thermophila SB210
CBN76132     148 RGVKE 152
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