6W6L


Conserved Protein Domain Family
DUF2053

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pfam09767: DUF2053 
Predicted membrane protein (DUF2053)
This entry is of the conserved N-terminal 150 residues of proteins conserved from plants to humans. The function is unknown although some annotation suggests it to be a transmembrane protein.
Statistics
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PSSM-Id: 462890
Aligned: 33 rows
Threshold Bit Score: 130.862
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6W6L_4         2 TLFHFGNCFALAYFPYFITY-----------KCSGLSEY-NAFWKCVQAGVTYLFVQLCKMLFL---------------- 53 
XP_015791013   2 SFYYFVNCISLTFLPLFFVY-----------KFTPLSEY-GSIYRCSFALFAYLVVQIVKLTIM---------------- 53 
XP_001608878   7 A-----TCLVLIVSPYWIVY-----------TKSSLAQNvNNGWTALRSCGYYVAANAVKVFIM---------------- 54 
EDL44650       2 ALFHFVNCSLTAFTPYYIIY-----------DGFKLSKNaGSTKLFFLVCFYYIVSQILKLFTL---------------- 54 
A0C428        30 AFSHLINCLLLAFGPFFVVY-----------KARSLAEQ-GAYKTVLISILGCLLTQFCKLFLL---------------- 81  Paramecium tetr...
XP_003284712   2 TFLIFTSCALLIFGPIFVVA-----------NASVLSQV-KYGHYFLFGFLSNLGWQIAKLFIL---------------- 53 
Q54BM6         2 TFLYFSSCLLITFSPFYIIY-----------KSLKLNEI-KSNQLILYGFIGCIFTQFLKMLII---------------- 53  Dictyostelium d...
XP_004359663  65 TFLYFTSNLLVTYAPFYLLY-----------KSTSLNEF-KSFNIILQALCGNLITQVAKMMLL---------------- 116
EFA83128       2 TVLHFLSCVSITYIPLYIAY-----------KSTKVGEF-KALSTVGYGLIGNILTQLAKMMFL---------------- 53 
EFC41026       2 TFSHFISTFALSFISPYIVYfskqssskgekENSSIGTE-RRFSNVVLGIMAFGLTMFCKMFLIaivirgnenqqlqsga 80 
6W6L_4        54 ---------ATF-FPTW--EGGIYdfiGEFMKASVDVADLIGLNLVMSR-NAGKG---E---YKIMVAA--LGWATAELI 112
XP_015791013  54 ---------ATLpLPAFlfDH---------------LIDCLGLYYVLVK--QQKAsliQ---VKILGVA--VGWSFGESI 102
XP_001608878  55 ---------ATG-IPELv---GNYiftEDIVMAILNSALYLGIMLPLRG-KTNAStnvN---NIVLGIG--IGWSVPENI 115
EDL44650      55 ---------AFFsIGLL----QNMnlfNIIFQECANFIDLAGLYYILSH-KHTNTinlK---ERILSVG--LSWGFYESV 115
A0C428        82 ---------ASL---------SVIteqLIHIKLLFDLIDCYGIIL-----VAKQKtniDdkiSRVFAIA--IGWALMDCV 136 Paramecium tetr...
XP_003284712  54 ---------GSF-YPFF--DMEIYdpvQEIIKIVGMISEIIIVYFTLRY-LLKEKnkaNiskHKIIVLGftLGWFTVGSL 120
Q54BM6        54 ---------ATF-LPSF--NTTSIgiyPEIIKIICNVIDLFSMSLVLK--FAEFSgskD---YRILGIG--IGWSFSHAI 114 Dictyostelium d...
XP_004359663 117 ---------ATF-FPSF--DTSTFslyQGLVQCLSVVMDLFAIYF-----VTGFS-------QSKFAIA--TGWALADAL 170
EFA83128      54 ---------ATF-LPSF--DSTIFsvlQELVRLVNVLIDLFSIYTLLQMsHAPKD-------VRAFGIG--LGWVIAD-V 111
EFC41026      81 infddnkqiATLgFGFFi---------TEILKTLIGSLDLIGMFFILSS-----KwllGdqtSQLYGCA--IGWTMGDNL 144
6W6L_4       113 MSRCIPLWVGARGIEFDWKYIQMSIDSNISLVHYIVASAQVWM 155
XP_015791013 103 LTRLIDFYVNAKSMQFDWRHIISAMDANVTLIQTICTCTLIWN 145
XP_001608878 116 GRTVFQTVSTLSNADETNMFLYEAFQAHLHILVSIIVTALLFL 158
EDL44650     116 ATNFFPFFIGGRSMDFSLKHIYRSISANTFMFSNLSKTCLLFM 158
A0C428       137 MKHLFTFIPNATTDEFTWTFILRGFTANLEFFETLFLVGLLqs 179 Paramecium tetraurelia
XP_003284712 121 LTQFLPLF-NTLGVEFNWVYTFNALDNNIKLLEQFALNTCIYL 162
Q54BM6       115 MSQLIPLLMGTLSISFDFSYYLDSIESNFIAIQQLVVFKLLYL 157 Dictyostelium discoideum AX4
XP_004359663 171 -QRLPQLWLGSLPLEFDSIHLIRSFESNTHTAHVIAIILLIgh 212
EFA83128     112 LPRFFSLWVGALPLEFDANQLIGSLQSNVNCAHTVAIVLLLas 154
EFC41026     145 FNRLLPLWFSTRGLQFELKSLQMGVYSNIVMLEWIAVATFVFL 187
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