Conserved Protein Domain Family
Methyltransf_21

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pfam05050: Methyltransf_21 
Methyltransferase FkbM domain
This family has members from bacteria to human, and appears to be a methyltransferase.
Statistics
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PSSM-Id: 428282
Aligned: 113 rows
Threshold Bit Score: 52.5677
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9XXL6             85 NCVYPKlrplkgkyveffDEFSSLT-E--ECDNLKAYnaLDIRHVYNkdetk-yialpRNQSQ---LLtm--vTLGIGHD 155 Caenorhabd...
WP_013109532       49 QIGACDgm---------rFDPIHDFiKanSSTIEGVV----VEPLPDlyaa---lcrtYAACQgirPI-----NCAIHNS 107 Planctopir...
Q39T64             42 QIGANDgv---------sFDELYSFvT--SRKCRGVV----VEPLKIyfek---lkqnYSRYPdiiPV-----NCAVHQN 98  Geobacter ...
jgi:Sfum_3336      10 QIGANNgv---------dEDPLRKHiL--RWNLKGIL----VEPLPDiyeel--iqnyKDQAQlhfE------NAAVAGH 66 
jgi:FraEuI1c_2459  62 QIGANDge---------mGDPIHDAiV--NHGWRGVV----VEPLPHlfta---lansYRGVPgisCE-----RTAIGTE 118
jgi:Aazo_5155       8 HVGVHTg-----------QDTEF------YLKKGFRV--VRIEAHPDicestkrrlnsYIESGqltFL-----NVAVSSK 63 
Q8XZA7             34 DSGASNgr---------kGSNTWLLeS--RYGWSGIC----VEPNAE-----------AFRQLranRG-----CVCLDCC 82  Ralstonia ...
WP_012628740       51 EAGAANgk---------dASSCYLLeK--EFGWTGIC----IEPNNY-----------FFDQLvhnRPnsiceNICLSNS 104 Cyanothece...
EEC48409           83 EMGALDgr---------lYSNSFAFhK--ALDWKGLL----VELTPEsylrl--venrPSELAvv--------nAAVCDQ 137
NP_001164122      126 ECGALDge---------tRSNTLYFeR--YYGWVGLL----IEADPLnfvkm--lkkgRRAYLsp-------tCLSVNPY 181
Q9XXL6            156 ImgeislkelhpntqfygadpspevnkILYEDKLGGK------YYRYAVSGETGVQKS----SIYTe------------q 213 Caenorhabd...
WP_013109532      108 A--------------------------TTMPLHRVRS------SSLGTLPEWAIGISSfdrsHLHRlg----------ip 145 Planctopir...
Q39T64             99 K--------------------------KKAVLHYVDP------AKLDLLPEWVQGIGSldpnHYKQsg----------lp 136 Geobacter ...
jgi:Sfum_3336      67 D--------------------------GKISMWRHEThdtlrlKALSKTASLHREIAF----KRLNtnp---------qf 107
jgi:FraEuI1c_2459 119 E--------------------------GTATMYAVHW----------KPSDPVWVIGL----SSLRrevvleskelipdi 158
jgi:Aazo_5155      64 E--------------------------DPITFYANLD------RSFWGTISPDRVISS----DRSF-------------- 93 
Q8XZA7             83 L--------------------------YDRDGAVDFLea--agVYGGIMEAYDPRHLSftrrMLGErw----------pe 124 Ralstonia ...
WP_012628740      105 T--------------------------RTVTYIEGSEnt--vsPYLGGIKSNLEQVKY----MGKEv------------- 139 Cyanothece...
EEC48409          138 P--------------------------KKIHYYSKQRqpavsgVWEFAPTEFRELWWP----GIT--------------- 172
NP_001164122      182 P--------------------------EIVSFLQRSNmgrianDEVVEDEVISDDYGKk--kS----------------- 216
Q9XXL6            214 KEELAYRTETTEHIAvdYF-FKYIlNKSLIDILWIDVEQNE---FPIMeqlhrNGaidnAGV-TICQMNIevhsgvfeqP 288 Caenorhabd...
WP_013109532      146 DSAIEEVPVPCQSLA--EL-VEKT-GFSSVELLQIDTEGYD---AEIIl---------sIDF-SSFRPTV---------I 199 Planctopir...
Q39T64            137 SDYIVSEEVECVHLM--EL-IRDN-KFEHVNLLQIDVEGYD---GEVIk---------mIDF-DVIRPKM---------I 190 Geobacter ...
jgi:Sfum_3336     108 GDYLREIVVTSISLS--SL-FAKY-GISRLSLLFIDAEGYD---WKIVr---------eALS-IGIKPSI---------I 161
jgi:FraEuI1c_2459 159 EDRIEEIEVPVMRLE--TL-LVKH-GIVHIDLLQVDTEGFD---YEIIr---------qIDFgSPWAPRH---------L 213
jgi:Aazo_5155      94 STRSVEMTLTGRRFK--SI-LEEF---GIPYYLKVDIEGSDlcpISEL-----QQ--------LDTKPQF---------I 145
Q8XZA7            125 GAPAPTVSKAARTIR--SV-LRSAgAPRTIDYWSLDTEGSE---LALLk---------nFPF-DEYRVRV---------L 179 Ralstonia ...
WP_012628740      140 VQKGKAVEKPATTLE--AL-LKKHkAPAVIDYAAFDIEGSE---LDVLe---------tFPF-DDYVFLA---------L 194 Cyanothece...
EEC48409          173 --LADTQEIDCRPLR--EIiATNVgEPAFFDFFSFDIEGSE---FMALq---------gLDF-SKVGFGI---------I 226
NP_001164122      217 ----PIVNVQCFPFY--TYlLALN--ITVIDYFSLDVEGSE---LNVLk---------tIPF-DKINIRT---------L 266
Q9XXL6            289 IGEKQmfhdfvwrvledrryimlrsyYADPFIRT--FMinvgdEECRNPL 336 Caenorhabditis elegans
WP_013109532      200 RFEHSrnsq-------------gmpdNIYHQVID--HL-----HAGGYEV 229 Planctopirus limnophila
Q39T64            191 KYEHQsl-----------------kkEEQQEITI--LL-----ESHGYEV 216 Geobacter metallireducens GS-15
jgi:Sfum_3336     162 YFEHLn-------------------lEQGEKIESrtRL-----LQNGYQY 187
jgi:FraEuI1c_2459 214 IYEAChl------------------gVDLEKARA--LL-----RDAGYKI 238
jgi:Aazo_5155     146 SIESKesnk--------------afwNALLEELE--FL-----KKLGYQK 174
Q8XZA7            180 TVEHNn-------------------gPIRAPIRG--FL-----EARGYVR 203 Ralstonia solanacearum
WP_012628740      195 SLECDg--------------------SIRAPISQ--LL-----ESNGYRQ 217 Cyanothece sp. PCC 7425
EEC48409          227 FIERQpn-----------------npMKNLAIRT--IM-----ERNGYIY 252
NP_001164122      267 SVEFFhv------------------kEGDDGVRT--YL-----EDKGYIV 291
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