Conserved Protein Domain Family
TMEM254
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pfam14934: TMEM254 
Transmembrane protein 254
This family contains proteins found in eukaryotes, including human Transmembrane protein TMEM254 (C10orf57). The exact function of this protein is still unknown, however it is thought to be an integral membrane protein. The protein sequence is 123 amino acids in length and has a mass of approximately 14.2 kDa. The family also includes some longer proteins that possess an N-terminal dehydrogenase domain, pfam01073.
Links
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Statistics
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PSSM-Id: 464385
Aligned: 37 rows
Threshold Bit Score: 71.5225
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EDP07354      14 LLVFGMATGVAGAFFPVTRSWPVIKQtfqLGITLFRSLFGYQVVMGSAIVAHIVEAAIIAYMCAKNKVSTKDTwgWAGYT 93 
EFJ26012     387 GILAAMFALFCSAFVPDPFMGPFECVr-sLGILLHGSVRNLKLVFLTACLAHAAEASYAWKLAKSVDPENAKG--WFWQT 463
EDQ65407     388 FLLGGMFLLFLCVYVPAPFMGPLEFIr-wIGLFIFRSQETLRIILYLACLAHLLEGIYAWIVAMKADRKNARG--WFWQT 464
ERN11556     386 FCIIGMSLLFCSAFIPHPYLGQMEWAr-sLHLFVFRSQFLLRIVFFVAVALHGMEAVYAWYLARRVDPYNANG--WFWQT 462
XP_009386805 387 FSILGMTILFCAAYVPP--VGPFAWTr-aIGLFFFRSVWTLRLVFNVSAALHVSESIYAWYLSRRIDPANSKG--WFWQT 461
NP_001305494 387 FCVIGMSALFAAAYLPD--YGPIPFIr-aVHLFFFRSMLALKVIFVLAAAAHVGEAIYAWNVAKTIDPANARG--WFWQT 461
O22813       386 AVTIGMSALFAAGWLPD--IGPVPFLr-aIHLFFFRTITIVKAVFIVAVVLHVAEGIYAWFLAKRVDPGNAMG--WFLQT 460 thale cress
XP_002887640 383 FCVIGLPSIISVAWLPD--IGPIPLFr-aIALFIFRSMLVLRIASGIVVTTHVSEAVYALWLAKRVDPKNAKA--WFWRT 457
XP_006601383 400 FCVIGMISLFCGAFLPD--IGIMSLLr-tTCLFVFRSMWVTRLVFLLATAAHIAEAIYAWYLAKRVDPANARG--WFWQT 474
XP_002275214 387 FCIIGMFVLFCAAYLPD--IGPVPIFr-aISLFFLRSMAIIRVVFLLATAAHIGEAVYAWHLAKRVDPANARG--WFWQT 461

EDP07354      94 LLIGYGAIHHLK 105
EFJ26012     464 LALGFPSLRLLL 475
EDQ65407     465 LALGYPSLQYLL 476
ERN11556     463 FLLGFFSLRFLL 474
XP_009386805 462 LALGIFSLRFLL 473
NP_001305494 462 FALGIFSLRLLL 473
O22813       461 SALGFFSMRFLL 472 thale cress
XP_002887640 458 LLLATFSLRLLL 469
XP_006601383 475 FALGFFSLRLLL 486
XP_002275214 462 FALGIFSLRFLL 473
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