6XP5


Conserved Protein Domain Family
Med21

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pfam11221: Med21 
Subunit 21 of Mediator complex
Med21 has been known as Srb7 in yeasts, hSrb7 in humans and Trap 19 in Drosophila. The heterodimer of the two subunits Med7 and Med21 appears to act as a hinge between the middle and the tail regions of Mediator.
Statistics
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PSSM-Id: 463241
Aligned: 79 rows
Threshold Bit Score: 80.3271
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6XP5_U         1 DRLTQLQEAMDELLEMFLSAFFWVERHHDLKTFGPNDKipdl-kadQPK----------------EVDTKSPEEYKAGQL 63  Chaetomium ther...
Q7PTL0         3 DRLTQLQDTVNQQAEHFCNSIGILQQCSVPSKFAGFERtgsqtpqqqv--------hqqqqlpqqQQQQQQPQQQEDFPQ 74  African malaria...
CDS38069       3 DRLTELQDAINLQAENLGNAVGVIQQLAQPSLFRelnhngrrekewASNp--------------eFQALLQSQSQEDNAH 68 
XP_002117348   3 DRLSQLQDAVNQLAQHLCDSVGVLQQSAPLSYFDefeshdrgllsiQWMqtnqilysntvsylavHNPTTNGENVENNLD 82 
XP_004995796   3 DRVTQLQELLQALMEHYRNAVGVLHMQAGEAAME-PAPssakkqpqkq-------pqkqqnngeeGAVASARQQVQQTVD 74 
EFJ18896       2 DIITQLQDQVNKIAFLAFNSVGSLQRDAAPVRLSQNYPdpqalapgapp-----lpgqqqqqqqqAQQSQQPQQQQEQAP 76 
XP_009114546   2 DIISQLQEQVNSIAAITFNAFGTLQRDAPPVQLSPNYPeppaaaa-------------tttttttATDGDATAAFPEQPK 68 
Q8W0T0         2 DIITQLQDQLDEMAVLAVNTFGTLQRDAPPDRLSNSYPdplnpnpkpedvstkpqvqgqpgapppAQAQPPAPDLSEQPK 81  sorghum
EFJ52925       4 DLLTELQRQLRDVNDQFAIVIEQLIHIAPPAPLEGDSGqivaeep----------------------savshaELQVKAL 61 
ESS28669      10 DPVTRLQQLLTNFSRHLYDVVQQVPELAPPLPLSPTDSssssass--------------ssaspaSGEAEKRSQVESFLL 75 
6XP5_U        64 QLARDIIVKEQQIEYLISTLPGLDNSEREQIQLLRELED-DLVTAEAQRQEALKER-DEVLGKLDALLRGLER 134 Chaetomium thermophilu...
Q7PTL0        75 LFSTLISRCAKDIDTLIESLPSEESSIELQVQSLQRLEA-ENKESAEKLEEIVRKG-ELLLEKIQAALSDIAQ 145 African malaria mosquito
CDS38069      69 KFAVTIATTAKQIELLINSLPAEEASLELQDEVTRQLLS-DYRKESAKLVHLITKSfQTRLSKVRQLLSKIAe 140
XP_002117348  83 VFATLITRTAQDIDYIITSLPDIRVSQQNQEKAIERLQE-ENAQARQQLVEAITRA-EGVLLKVKQIKNQVAa 153
XP_004995796  75 VTKHAILQTVKDINLFCDHLPDIKQATNTNDDDLDELHR-KNAEAASLLRTKVQLA-EERLALLRGRITDITN 145
EFJ18896      77 EMASTLVQAAKQFDALVAALPIAEGGEEAQLKRIAELQQaENEEIGKELQLELDLA-EEELKLMRELFHTAad 148
XP_009114546  69 QLSADLVKAAKQFDALVAALPLSEGGEEAQLKRIAELQV-ENDLIGQELQKQLEAA-EKELKQVQELFGQAAD 139
Q8W0T0        82 AMSHALVLAAKKFDALVAALPLS--SEEDQVKRIQELQA-ENEVVGLELQKQLEAA-ERELKQVEVLFNEATd 150 sorghum
EFJ52925      62 ELSKGIAQRFKDINTIISKLPDAYEPPEKQDARIGVLLH-EHHALRKELGLVMQEA-ERKLEEIHGCYEAIAQ 132
ESS28669      76 RSANNVAAIMHAIETEIGNLPSSLRTREETQRRIAFLEK-ENDRAAKELQAVAAEA-TRVREALRQLLRhsit 146
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