Conserved Protein Domain Family
TpcC

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pfam12642: TpcC 
Conjugative transposon protein TcpC
This family of proteins are annotated as conjugative transposon protein TcpC. The transfer clostridial plasmid (tcp) locus is part of some conjugative antibiotic resistance and virulence plasmids. TcpC was one of five genes whose products had low-level sequence identity to Tn916 proteins, having similarity to ORF13 homologs from Tn916, Tn5397, and CW459tet. This family of proteins is found in bacteria. Proteins in this family are typically between 302 and 351 amino acids in length.
Statistics
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PSSM-Id: 463652
Aligned: 25 rows
Threshold Bit Score: 103.707
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CGS-ASRI:BpOF4_21899  98 YTRDFVSEYINISADEEEreqrldELERYFVSGFDVSSLEDTsef----agsRNVTSIRLLDIKRA-GQNE---ANVHYL 169
CCF62141              57 FAQEFVVTYLSSNDSQKE------RLAEFVADSSRMRLPKTG----------RQVTDSAVVFVRRTdVQGSldiWTVTVS 120
CAQ03328              94 YAVGYVGAWLSSTRDDSA------SLSNYFAGSTLSLS--------------TTPFEYRNIAVASLtPSTAgdlMTVVVA 153
EST18077              99 FAQLYVAAYVEAGKGTEA------SLAPYYPLMRDISLQAEPg--------aQHVDRLAAVRVTQA-SPGY---WSVTVA 160
CDA69612              93 FAQNFTKEYLTY--ENRKeeeyksRLKPYVTSGLLTGSLVDCtad----aeaGYVQAYRIEDYTE--EQKD---VYVFAE 161
Q82YS9               118 dgMKLVDRLFTVSSKLEGkeyweaQITPYLAAGLRAEDLGLDktnd--drvaRNVRFIRLETVDY--KESL---YSLYYD 190 Enteroc...
EST17975             100 VAARFARAYLGWDESKAAer--eqLLAAVLPPDTDTTMGWDGhgr----qdvLAVQPGAVTTTKNAqARVR---VEVLIR 170
CBG71115             177 FAEQYATLCLTYSPETASdr--raALARYTSAGVDPECGWSGegtrkaltatWDGTSEKLPEYND--------------- 239
Q82EW2                58 FAEQYAMLCLTYSPDGASkr--rdSLARYASSGVDPECGWSGegtskavsavWDGTSEKLAEYGD--------------- 120 Strepto...
jgi:Theco_4006        89 FAADFASEYFTWSDDNFSer--ssRLAPFISNISQDAGLKSFdik-----gsSRVLSAEVYDAKKI-NDSQ---VDVTVV 157
CGS-ASRI:BpOF4_21899 170 VAydiketeevekevtkeegegedkkevtetvMEEEERVTSHDIEMVIPL-TTDGEG-FAITGYPSLANSH-----Mkst 242
CCF62141             121 VR------------------------------LGGSGNTAGARHFYRVAV-SLTEGR-LRALGLPAAVTPPglgldL--- 165
CAQ03328             154 ADvkd------------------------eqlSDSKKAPSWPRRYFQVAV-STSGST-LAALTLPAPVAGPgstt----- 202
EST18077             161 ALitpssktga-------------asdktqggSQDEAGAGPVLRYFQVPVkTAGTGGgYEAAALPAEVAAPatggeApql 227
CDA69612             162 VCytgrs--------------------lnedgQTYTTRETKNTVTLRVPV-YAKGGS-YIIEDLPLMVEDEsiyipEykt 219
Q82YS9               191 VRf--------------------------------tEGKEWRQVQVILPV-SYAENE-LKLLDRPTLMNLAkt--sEsnk 234 Enteroc...
EST17975             171 PVvetepa-------------------kdkkkAETPAQDAARWVGLDVPV-AESGGQ-IVVTGRPGLVGIPkh------- 222
CBG71115             240 -----------------------------------------HGRYLGIQV-RTDDGG-LTTLTVPVYVKNLttgegIria 276
Q82EW2               121 -----------------------------------------HGRYLGIQV-RTDEGD-LTTLTVPVYVKDLasgegMrva 157 Strepto...
jgi:Theco_4006       158 VRrevtlpqdnmssaggp--------asvsavsntnmdravKKAYMVVPV-TITDKG-PVIRSYPRFVTelik------- 220
CGS-ASRI:BpOF4_21899 243 iq-------yepsaLEGA----DTTSQEREVLGD-FLTEFFTSygi-sdETLAFMA------NVDRGLSHKV-------- 295
CCF62141             166 --------------ATTYkttcPADAPVSTVASG-FLAAFLTGs-----GDITRYI------AQGSGITALApppyt--- 216
CAQ03328             203 -----------napPTDYpasvSTADPLGGSVMS-FLTSYLTGq-----GAVEPYT------SPNAGISAITpapyta-- 257
EST18077             228 --------------dygApvpaDTHDPAVATISE-FLAAYLTGg-----GELDRYL------SPGTSLVAVSpapytkvs 281
CDA69612             220 ep----------------yygnAVSDEKASAIKT-SVENFLKAyfeqdeSVINYYLggdcdkQKFTGLNGRFs------- 275
Q82YS9               235 v---------aydeQRFIpkgkEVNEEETKKLTE-FTNRFFELyvk-ndEKLGLIA------NVKGLEHATLe------- 290 Enteroc...
EST17975             223 ------------gpKAPDtpttQTDPELSTQTEG-AVDKFFSAyaagdtEAVTAPG------ASVPALPAGVe------- 276
CBG71115             277 gdvgempmpprsdvPEVDrdseDVDTALGQQLQQtVLPGYFEAwaksdrTTLARFT------AQGATLAATTglsgrlse 350
Q82EW2               158 gdigempmpgranvPELDkddeVVDTSLSQQLQEkVLPGYFEAwgasdsTAMARFT------APGATLSATAglagrltg 231 Strepto...
jgi:Theco_4006       221 -----------getESQApgpsITDTNILNMGKE-LTESFLRSwydgnlSQLKYYY------SDIANIPSSVtks----- 277
CGS-ASRI:BpOF4_21899 296 ------------YQEHQIMESVK-DSDNGEFVVRVNVTyrdQETSIAAIHSFHMSISEENGRFFVQ 348
CCF62141             217 -------kadvvSVNADDSSCGK-SGSKIRVLASVTPS---AAGAEAAALEYPLTMINNGGQWQVQ 271
CAQ03328             258 ------ltpvsiTADAKPVAKPQ-DGSTAAVLATITTQ---NAVSQTLTATYALTLTARANRWEVS 313
EST18077             282 v--tqlaeqggdFAANAPVT----EGARRELLVDVAAT---GTDGQVRPLTYALALKARAGRWEIA 338
CDA69612             276 ------------FENIEKISCYQdTHNN--IVCIVEFKikdAENNVKMLQKINLSMTESGGKFYIQ 327
Q82YS9               291 ------------KVDITSLR----ETGQGVYDVRGTYQf-sYEGKSPLTSNFSLQIEATKDSYFIK 339 Enterococcus faecalis
EST17975             277 ------------YKGLVSWSADAgSGDSRTGTARVSWSlggASVEQVYRVTITQVSSSDAHRWQVD 330
CBG71115             351 pqvndvvalvpkGVQGSAPYSYK-TGQAVELRVVVDWA---DPEGDTARRSYRITVVNTAQGWFIK 412
Q82EW2               232 pkvgtaealvpaNVQDTKPYAYR-AGQSVQVRVVVDWS---EGESRIVRRAYRMTVVNTAQGWFIK 293 Streptomyces avermitilis
jgi:Theco_4006       278 ---------nfvFDKVDSLNMYKvDGQENVMRIYASIIv-kSDIGESFTNSWTLDVTAKDGRLYIl 333
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