4WJ3,4RMF


Conserved Protein Domain Family
AspS

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COG0173: AspS 
Aspartyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
Aspartyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Statistics
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PSSM-Id: 439943
Aligned: 692 rows
Threshold Bit Score: 828.87
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4WJ3_M         9 MMRSHYCGQLNESLDGQEVTLCGWVHRRRDHGGVIFLDVRDREGLAQVVFDPDr--A-----ETFAKADRVRSEFVVKIT 81 
NP_972193      4 MQRTVTCGGLNKDFAGKTVVLNGWIHRKRDHGGITFLNLRDRYGLTQVVVDDDa-sE-----DLKALAVSLKQEFCIAVE 77 
NP_212580      1 MFKVIKCNELNEKLIDKKVEINAWVKKIRHHGKFIFLNIRDRYEKAQVLVNEE---------KLLKIAEKIKLEYCIKIQ 71 
WP_013252932   4 MKRTATCGELNSSRVGETVTLNGWVHRNRDHGGILFINLRDRYGITQVVIDEDa-sA-----PLKEKAKELKFEYCIAVV 77 
WP_014270669   7 SQRTATCGALTKADNGKTVILNGWVHRDRNHGALHFINLRDRYGITQVVVDDDa-sI-----ELQDTAKELRMEFCIAVT 80 
WP_015492849   1 MRRTNTCGELRASDIGKEVCLEGWVRFSRDHGGVRFIDLADRYGITQVVFDPEdlpSnanrdAIAKTMDTFSRESCVLIN 80 
WP_020448299   1 MMRTHTCGELRSSDIGKDVTIAGWIRFSRDHGGVLFFDVADTYGITQAVYDPEsitAdg-yaELGDILKTFSRESVIKVV 79 
WP_024266507   4 YKRSHTCGELTAAQAGERVTLNGWVHRNRNHGGVHFINLRDRYGITQVVIDEDa-sA-----DLRDTAESLKYEYCIAVE 77 
WP_014342679   4 PRRTIACGELRRCHVGTVVVLNGWVHRKRSHGTVSFFNMRDRSGIVQVIVSQEe-nA-----SLWSTVNRIRLECCLAVE 77 
WP_048111220   1 MRRTNTCGELRSRDIGKKVCLQGWVRFSRDHGGVAFVDLADRYGITQIVFDPEdvpKgtdvnNLSNIMRTFTRESVVSVN 80 
4WJ3_M        82 GKVRLRPEGARNPNMASGSIEVLGYELEVLNQAETPPFPLDEYSD---VGEETRLRYRFIDLRRPEMAAKLKLRARITSS 158
NP_972193     78 GLVRPRPDSMINKEMATGEIEVKALKIEVLSKSEVLPFQIDEKTN---ANEDLRLKYRYLDLRSKAMQEHIMLRSKFTFA 154
NP_212580     72 GLLIKRPPNMINANMKTGHFEILAKNIEIISKCNELPFMIEDDNN---ASENSKLEYRYLDLRRDSLKNKIILRCQATHL 148
WP_013252932  78 GIVRRRPDEMVNKDMNTGEIEVAASQIEILTKCDVLPFMIDEKSD---AKEDLRLKYRYLDLRSFSMQRKIRLRTDVTFA 154
WP_014270669  81 GIVRLRPDSMVNPEMATGEIEVKAEKIEILSKCAPLPFQIDDGNE---PREDLRLKYRYLDLRTQGMQQRMKLRNDFIFS 157
WP_015492849  81 GKVRARVEGTAVESNPTGEIEVLITHAELLSKSKLPPFEIGDQKEgvlPDEDTRMKYRYLDLRRTDMIRTMEFRSRLVHL 160
WP_020448299  80 GTVRNRVPGTEDCRNNTGEVEVLIKTAELLNSSKPLPFEVAEQKGsmlPSEDLRLKYRYLDLRRHVMAENLRFRHSVVTS 159
WP_024266507  78 GTVRRRPDSMVNTDMTTGEVEIQADTIVVLTTCETLPFMIDERSE---TNEDLRLKYRYLDLRSFSMQRKIKLRADVSYR 154
WP_014342679  78 GVVRERPPSMINRALHTGEVEVHARTLYVLSENAVLPFRVDDVVH---AHEDIRLKYRYLDLRSQRMQERIALRSRVALA 154
WP_048111220  81 GIVRKRVEGTDDGRNPTGEIEVLITEAELLNRSNSPPFELGDQKEgvlPNEDTRMRYRYLDLRRTEMVQAIETRSKFVHL 160
4WJ3_M       159 IRRYLDDNGFLDVETPILGRPTPEGARDYLVPSRTYPGHFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQP 238
NP_972193    155 VREFLTSKDFLEIETPTFIKSTPEGARDYLVPSRLYPGKFYALPQSPQIYKQILMVSGFDKYFQIARCYRDEDARGDRQP 234
NP_212580    149 IRNFLIKRKFLELETPTFVKSTPEGARDFVIPSRIHKGSFYALPQSPQLYKQLIMIAGFDKYFQIARCYRDEDSRGDRQP 228
WP_013252932 155 AREFLIGKGFMEIETPTMIKSTPEGARDFLVPSRIHAGKFYALPQSPQLYKQILMVSGFDRYFQIAHCFRDEDARGDRQP 234
WP_014270669 158 IRKYLEEKNFLEIETPTLIKSTPEGARDFVVPSRIYPGKFYALPQSPQLFKQILMVGGIDKYFQIARCYRDEDARGDRQL 237
WP_015492849 161 ARVYLESQGFLEIETPVLGRSTPEGARDYIIPSRVHPGTFYALPQSPQQFKQMLMVGGMDRYYQVARCFRDEDSRKDRQP 240
WP_020448299 160 LRTALNSRGFTEIETPMLVRSTPEGARDFIVPSRTSPGDFYALPQSPQMYKQMLMVGGMDRYFQLARCFRDEDSRSDRQP 239
WP_024266507 155 VREYLGTEGFLEIETPTMIRSTPEGARDFLIPSRLNPGSFYAMPQSPQLFKQILMVSGFDKYFQLAHCFRDEDLRGDRQP 234
WP_014342679 155 IRQFLSMKGFIEIETPTFICSTPEGARDFVVPSRVCPGRFYALPQSPQLYKQLLMVAGFDRYFQLARCYRDEDARGDRQP 234
WP_048111220 161 IRQYMEKNGFLDIETPILARSTPEGARDYLVPSRVHPGTFYALPQSPQLFKQMLMVGSMDRYYQIARCFRDEDSRKDRQP 240
4WJ3_M       239 EFTQIDIETSFLDESDIIGITEKMVRQLFKEVLDVEFDE-FPHMPFEEAMRRYGSDKPDLRIPLELVDVADQLKEVEFKV 317
NP_972193    235 EFTQIDLEMSFASREDVLSLTEGMMQYAFKKSINVDLPKtFERISYDEAIDIYGTDKPDLRFEMKMQDAAFMAEIGNFAV 314
NP_212580    229 EFTQLDLEMSFVKKENIFKLIENMLFLIFKNCININLPKkFKKITYKKAMNKYGSDKPDTRFELELQDISRNLKNSEFNI 308
WP_013252932 235 EHTQIDMEMSFVSKDDVFEVVEGMMSHIFDKTLGVKLEIpFQRLPYDDALNRFGSDKPDLRFGLEMKTVDELASKSGFNA 314
WP_014270669 238 EFTQLDIEMSFVKRDDVLLLIEELFNHVFKEVMDYDLPAhFTRLSYHESMNTYGCDKPDLRFDIPMFDVDDLASKSSFGT 317
WP_015492849 241 EFTQLDIEMSFCDSKDIQDLIEGMVSYMWKGLYGTELKTpFPHIGYRDAMERFGSDKPDMRYGLEFTKLTDVVRDVPYKI 320
WP_020448299 240 EFTQIDMEMSFVDMSDIQETIEFMLSEMWKNVYGEELKTpFPRVSFYDAMHKYGTDAPDIRYGLELHDVTEIVRNANYEI 319
WP_024266507 235 EHTQVDIEMSFVDQDDIFRLIEGLMEHVFKHTLNIDLKTpFPRISYDDAMNLYGSDKPDLRFDMEMQDFNAHVPGSGFGV 314
WP_014342679 235 EFTQIDLEMSFVSRDDVMRVNEDMLRYVFRTSIGVELPTfFPRLTYAQALDQYGTDKPDMRFKPVLQNADFMGMLGTFTP 314
WP_048111220 241 EFTQIDMEMSFVDAKDIQNMIEGLVAYIWKGLYGKNLKTpFMRIGYKEAMESYGSDKPDLRYGLKFVSLTETVKNAPYDI 320
4WJ3_M       318 FSGPANdPKGRVAALRVPG-----A-A---SMPRSQIDDYTKFVGIYGAKGLAYIKVNErakgvEG--LQSPIVKFIPEA 386
NP_972193    315 FKDAVS-LGGAVKALVVKG-----Q-Ae--AYSRKKIEELEAAAKIYKAKGLAWIKVTE-----GGakLEGGVSKFFEGK 380
NP_212580    309 FKDTLK-NKGSIKILIVKD-----K-Ad--KFSRAKINNLEEIAKLYKTQGLYFTKIEN-----NK--FSGGIAKFLKTE 372
WP_013252932 315 FKSVIA-EGGCVKALVASG-----C-A---GYSRKQISELEDAAKVYGAKGLAWMKVGE-----SG--IEGGVSKFF-DG 376
WP_014270669 318 FGEILA-NGGHVKALCAPKt---eG-V---DFSRKYITELEDAAKIYGAKGLAWIKVGA-----DKa-LSGGVTKFFGGL 383
WP_015492849 321 FQSIMS-EGGIVAGMCIKK-----EmG---EVGRNEVDRYIQYAKKCGLGGLTWMRCEN-----GV--LTSNITKYFTPE 384
WP_020448299 320 FKRILS-KNGKVECVNVKAeytkgG-SeegGVGRNEVDRLIEWAKSQGMGGLTWMRMTP-----EG--LQSNIVKYFSDD 390
WP_024266507 315 FESVVE-NGGAVKVLVAPG-----A-A---GYSRKQITDLEETAKTYGAKGLAWTKVSE-----EGt-LEGGIGKFFTDS 378
WP_014342679 315 FEEVVA-QGGSIRALVLPG-----K-Ar--CYSRRQIEALESIARAHEAHHLFWLKATG-----GG--LEGGIARFFAGV 378
WP_048111220 321 FQRIIK-SGGIVAGINLKA-----NiAg-eKIGRNEVDRYIHQAKKFGLGGLTWMRCKD-----GK--LDSNIVKYFTPE 386
4WJ3_M       387 NLNVILDRVGAVDGDIVFFGA-D-KA-KIVCDALGALRIKVGHDLKLL-T-----REWAPMWVVDFPMFEENDD-GSLSA 456
NP_972193    381 EA-EICSKLGAEKGDLILFVA-D-KY-KIACTALGAVRSKLGKDLGLLnP-----AEFKFAWIVDFPLFEWNEEeNKWDP 451
NP_212580    373 EQ-ELIKTYSLENNDIIFFTA-N-NNwETACKAMGQIRIKIANDLGLIdE-----NKFEFLWVYDFPLFEYDENtKTYSP 444
WP_013252932 377 IADELLASLEAQEGDLILMVG-D-KW-NVACTSLGAVRSKLGKDLGLIeA-----GTFRFCWIVDFPLFEYNEEeQRWEA 448
WP_014270669 384 ES-ELIDRLGANEGDLILFVAhE-NW-KKCCTSLGAVRTKLGKDLKLIr------KSFEFCWIIDFPLFEYNEEeGHWEA 454
WP_015492849 385 ILENIKTTLGAEEGDLCFLIA-G-PW-KSTYEGGGFLRRKIAEDLGMVpD-----NEFMFFWMDQNPMFEIDPVsGKRDA 456
WP_020448299 391 VKDALVAEMDAKDGDLLLYLA-G-SE-IAALKAGGELRRKLAADLGLLeG-----KPHQFVWLVDCPLFQKDSAtGQIEA 462
WP_024266507 379 SE-KILSELSASPGDLLLFVA-D-SW-KVSCTALGAVRKRLGSELELVeKggatpSHFAFAWIVDFPLFEYDEEgEKWEA 454
WP_014342679 379 ES-EVRRRLSAQDEDLLLFVA-DcRH-RVCCVALGAVRSALIRDESFPeK-----ELFSFVWIVDFPLFEWNPAeNKWDP 450
WP_048111220 387 VLDKIKQKMGAEEGDLLFLIA-G-PW-KSTYEGGGALRRKIAEDLDLVpK-----DEMQFLWLVDCPMFDIDPVsGKHDA 458
4WJ3_M       457 LHHPFTSPKC-TPAELEaNPGAALSRAYDMVLNGTELGGGSIRIHDKSMQQAVFRVLGIDEAEQEEKFGFLLDALKYGAP 535
NP_972193    452 AHHMFSAPQEkYIATMEeNPEPVKGDLYDLVLNGYEVASGSIRIHNPELQKRIFKIVGFDESEAEKKFGFLTEAFKYGAP 531
NP_212580    445 AHHMFSLPKKqYIANLEkNPKKTIGEIYDLVLNGVELGSGSIRIHNKELQQRIFKIIGFQKEKSEDRFGFFLKALEYGAP 524
WP_013252932 449 AHHMFTMPQEqYLDTLEeNPGAVKGDLYDLVCNGFELASGSIRIHDPEIQKRIFNIVGFSSEEAENRFGFLLNAFRYGPP 528
WP_014270669 455 AHHMFSMPQIeYLDTLEsDPGSVKGDLYDLVCNGYECASGSIRIHDVELQKRIFRICNFDDETAEERFGFLLNAFRYGPP 534
WP_015492849 457 FHHPFVLPTG---D-L--DDPDCGGACFDLCLNGNELGSGSERIHDAETQIEVFHRLGLSDETIQARFDYFVEALSYGAP 530
WP_020448299 463 FHHMFVCPENmD---LSgEITDIRGLSYDLVLDGSEIGSGSMRCHDPEVQHRILEMIGMSEEKIQDEFGFFIEALSFGAP 539
WP_024266507 455 AHHMFTMPQAkYLDSMEnDPGAVKGALYDLVCNGIELASGSIRIHDPRLQQRIFDIVGFNKEEAERRFGFLMNAFRYGAP 534
WP_014342679 451 AHHMFSAPQEqYLETLEqDPGSVKGDLYDLVLNGYELASGSIRIHDTQLQKRIFKIVGLDPEEAGEKFGFLTEAFKYGAP 530
WP_048111220 459 FHHPFVLPEN---D-L--DAPYVGGACFDLCLNGNELGSGSIRIHNPELQREVFRKIGMSDEKIEADFGFFIEALGYGAP 532
4WJ3_M       536 PHGGLAFGLDRLVMLMTGASSIREVIAFPKTQSAGDVMTQAPGSVDGKALRELHIRLReQp---------KA 598
NP_972193    532 PHGGIAPGLDRIVMIMAGETSIKEVIAFPKNSFAVSPMDDSPSEVDQKQLDELHLVIKe------------- 590
NP_212580    525 NHGGIAIGIDRLIMLMTKSTSIKDVILFPKNSFAASPLDNSPSKISNEQLKELGINIVdGdn---------- 586
WP_013252932 529 PHGGIAPGLDRLVMIMAGENSIKEVIAFPKNNQAYSPMDDSPSLVDEDQLKMLHIKLDmPe---------KE 591
WP_014270669 535 PHGGIAPGIDRMVMIMSEQTSIHEVIAFPKNTAAVSPMDDSPSELDQQQLDDLHLIINkPk---------QK 597
WP_015492849 531 PHGGIAIGIDRLCAILLNKDTIREVIAFPKNKRAVSLLDGSPSPVDDEKLQELQIISLaGdfdisdaeefNP 602
WP_020448299 540 PHGGIALGVDRLISLLLGCESIRDVIAFPKNKKFQSLVDGAPASVEEEKLSELQLLSLaGedfddsdfee-- 609
WP_024266507 535 PHGGIAPGLDRLVMLMSGESTIREVMAFPKNTQGINPMDDSPSPVDPAQLKELGLELKlPd---------RE 597
WP_014342679 531 PHGGIAHGLDRLVMLMTGSESIRDVIAFPKNTLAASPLDNCPSVLDKRQLDELHLTVHv------------- 589
WP_048111220 533 PHGGMALGVDRFVTLLLGKETIRDVIAFPKNKKAISLLDKSPAKVDESKLEELQIISMaIgdidf-dnleNT 603
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