Conserved Protein Domain Family
BLOC1_2

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pfam10046: BLOC1_2 
Biogenesis of lysosome-related organelles complex-1 subunit 2
Members of this family of proteins play a role in cellular proliferation, as well as in the biogenesis of specialized organelles of the endosomal-lysosomal system.
Statistics
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PSSM-Id: 462951
Aligned: 57 rows
Threshold Bit Score: 61.0657
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
OWR50444      42 THLFKKTNDYLQGEMSAGQDHYNLLEEINRLTITKYTDLRNLTVNLSKTLSEYNEMYNiLIKPLLLQIDDIDAQVSQFEI 121
Q3ASD7        86 GRDIAASIRYIDSTLAASRNLVQKLEEQNRTSTYRVESLDRLVAELQVAINVRDR----EVKALKGQVKKLGGQVASLVA 161 Chlorobium chlo...
Q6CEB6         4 EKTVKAAENLIDAQTDYTVTWLDSLEVVNRKQTHKYKQLAESTKGLENDREYLEGLNN-ENARYVDQLKQVRGHLDTLEK 82  Yarrowia lipoly...
XP_013936770  31 RNSYECMRKILELDTQSTLTNFNVMETLNNSTILRYRELEPYLDSLESETSKIRALDQ-ELAKNKPKLEQLEERTKKLAL 109
XP_002615500  53 GRALTQARKLVESDTEVSTIDLNLLGNLNTNQSLNYIKLESQLTSLEKDAEQREALTQ-ELHSLEDELTLIEKSVASLGE 131
XP_007375164  12 SLALNAASKIVESDTNVSTIDLNLLENLNTNQSLNYIKLEKNLDDMETNSNQLKQLKA-EFESHSQELISIENKIAILEE 90 
CCE43639      10 EHALTTLSKVIESDTNISTIDLNLLENLNTNQSLNYIKLENNLNDLEANGKHLKLLKE-EFDQHANLLVDIEKKVMRLEE 88 
Q6BR74        12 GNSLNVLSKLVEADTEISTIDLNIIENLNTNQSLNYIKLEQKLNNLEDNANSLEGLNN-EFKSFNTTLLEIENQINKIEI 90  Debaryomyces ha...
XP_011123396  35 QTVLSSLENLIEADSSAILGDLDLLHKINEAARERYKAMTEAAVGLETDSEYLRGRYA-ELKKYTKQVDDIDERVGDLEK 113
XP_002836154  11 NDVLATLENVIRADTEATVGDLDLLNRVNLHATERYKAIADAAVGLETDSEYLGQKYA-EIEKYKQQVDNLDERVGDLEA 89 
OWR50444     122 NAYRLDNYTKQLKARFK 138
Q3ASD7       162 TVDVLDEYIDTQESEYY 178 Chlorobium chlorochromatii CaD3
Q6CEB6        83 LVGEVDEWSKELEVKVR 99  Yarrowia lipolytica
XP_013936770 110 LVEQMDEWSAELEVKSR 126
XP_002615500 132 LVEELDQWSREVARERE 148
XP_007375164  91 ITTELDQWSKQLEHNVE 107
CCE43639      89 IVNELNSWSKELEMDLK 105
Q6BR74        91 ITKELDGLSIELSSKVK 107 Debaryomyces hansenii
XP_011123396 114 LVKELDEWCSELEVKIK 130
XP_002836154  90 IVKELEEWTGELEIKVR 106
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