5Z39


Conserved Protein Domain Family
DUF758

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pfam05527: DUF758 
Domain of unknown function (DUF758)
Family of eukaryotic proteins with unknown function, which are induced by tumour necrosis factor.
Statistics
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PSSM-Id: 461672
Aligned: 45 rows
Threshold Bit Score: 126.529
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5Z39_A         4 SGLK-KLIPEEGRELIGSVKKIIKR-VS-NEEKANEMEKNILKILIKVFFYIDS--KAIQIG-DLAKVDRALRDGFNHLD 77  Dictyostelium d...
XP_016661720  26 NVIK-LFIHERNANILDNLYRLAKIyTG-NKKESEKLTKNIIKIIVKLSILYRN--DQFDSN-ELELANNFKDKFRELTM 100
Q16HN3        32 NVAK-VFIDGTTASLLDNVYRLAKThTG-SKKDAERLVKNIIKIVIKIAVLHRN--NQFNAD-ELKLADRFRAKFQTLQM 106 yellow fever mo...
XP_021205891  55 SSARaLVLDEHAAKLLDQFLIVLR--ERvEKREAEKLVKHVIKSAVKLGVLRRH--SQLSAA-DDRALEAFRSKFHTVLM 129
PDM69629      35 KRLGkQVLPERAAALFDSLHALLRDcCA-EKEQADKLAKYAMKLTLKVGVLAKN--GLLDGErEQERLVKVKNHCHALAL 111
EFO15564      48 NNAK-LFVDDVTIRLFDYLYQILK--TAyNKVIAEKVVKNIIKLVVKLGVVLRN--EQFTAE-QQNQLAKIQRQMRQLCL 121
CCD77140      41 GIIK-LFLDDSSARLFENIFRLIKQyTG-NNKLAAYLTKQAIKLNVKALILISN--DILSDE-QLNHAYEFHEKCHQIAE 115
BAN39847     134 SGSAsFVMNDEMNNLLKAIEKLIEI-DA-GKEEAKKYEKFIMKLVAKCYMEWQH--KNISNE-QIYALDKPLRNAFTMFD 208
CDS42377     101 RKFAlAMLHPFSAAVMNDIHYLLKAhIT-PKAHFRKVDHIILRSLIKVGIVSEKllDDRSAVlQMRRVERLSRNFGLIFS 179
EGG21978     149 SGLK-KLIPEEGRDLISSVKKIIKR-VS-NEEKANEIEKNIIKILVKVFFQIDN--KTIEIQ-EFAKVDKALREAFNQLD 222
5Z39_A        78 RAFRYYGvk----kaADLVviLEKA--STAL-KEAEQETVTLLTPFFRPHNIQLIRNTFAFLGSLDFFTKVW----DDLe 146 Dictyostelium d...
XP_016661720 101 ITVSFYE--------IEFS--YDKNylINYL-FKCREILKELTKRHLTDKTLSRVDKIFDFFSNSVFLDSIFinpaVSE- 168
Q16HN3       107 AIISFYE--------VDYS--FDLNylLKSL-QEVHGLLKSCVDRHLTDKSLGRIEEVFAFFSDPTLLETAFr--qESP- 172 yellow fever mo...
XP_021205891 130 AVVSFCE--------VEFS--YDRGflQDAL-RDSHQSLKSVVERHLSDKSVSRLAGVFALASRGELLDSLF----SGQ- 193
PDM69629     112 AVCSFAT--------VAYS--YERDyiMPLC-GSLRAELAPIVDYQLSDKSSARLAYFFDTLCTPAVMDELFr--pA--- 175
EFO15564     122 TVISFGK--------VAFS--YDYTylNALL-KETYRRLLPLVEQILSDKSKQRLDMIFEHLCKDSVLDSLFr--aDGQ- 187
CCD77140     116 IALRLGRpkrrlmpgVEPS--IDKl--IQTM-KEANQTLIEAVKHHISQQSQDKFKEFSDFFCRREFVVEVFt--nKVK- 187
BAN39847     209 QLFRYFGlkkaeylqAGFKn------lVDLLnNEIKTQLIQTLRPCLSPKNLSKLRDLFSLFFNVEFFERVWsktdPKDe 282
CDS42377     180 DLSSAAEeatvlpstSSPScrLDVSvlLDTL-KKLQEALNTLIESQLSPNSINQMNSVFEELQDARLWQYIFdhsiASSd 258
EGG21978     223 RAFRFYGvk----kgTDLLpiFDKS--AAAL-KEAENEAVTLFSPYLRPHNLQKLKSTFAFLGSADFFIKVW----DDMe 291
5Z39_A       147 IEDDLFLLISALNKYTQIE 165 Dictyostelium discoideum
XP_016661720 169 LTETVQILINDLKELLDKD 187
Q16HN3       173 YRDLMDKIIADLNKAMENG 191 yellow fever mosquito
XP_021205891 194 VDEDVLKLSRMLRKELDRG 212
PDM69629     176 HDKLLKRFAADIDALIESQ 194
EFO15564     188 HWKLLPKIIIDLEVLIDRK 206
CCD77140     188 YSTHMEKIYDDLEDMMDRG 206
BAN39847     283 VSDHLFNIVQSMNQYNSFP 301
CDS42377     259 EWQLVRNLRNSFHKLIEAK 277
EGG21978     292 IEDDLFLLISALNKYTQIE 310
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