Conserved Protein Domain Family
GCOM2

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pfam15328: GCOM2 
Putative GRINL1B complex locus protein 2
This protein family is named Putative GRINL1B complex locus protein 2. GRINL1B is short for: glutamate receptor, ionotropic, N-methyl D-aspartate-like 1B. The name indicates what sort of receptor it is thought to be, a ligand gated ion channel specific to the neurotransmitter Glutamate. This family of proteins is found in eukaryotes. Proteins in this family are typically between 325 and 463 amino acids in length. The protein is thought to be the product of a pseudogene with a role in helping assemble a gene transcription unit.
Statistics
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PSSM-Id: 464649
Aligned: 32 rows
Threshold Bit Score: 112.167
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_012657417         27 MLKRQERLLRNEKFICKLPDKGKKILDSVAKLKAAIAEHEEVRGKSKLFHPVSIDCKLRQKAVA---------------- 90 
EGI69710             26 LLERQKKILANKKFISKLPDKGEKIINFYNKIQKELEHRNEVEEAANVLSRLNIASEGKMAMSKlewtgkynerddenmt 105
EDS29103             41 LKLRQELLLNNKGRVAKLPDKGAKIRLFYEQIVKQLEAHCNVDRAAELFSELNIASVGKRSLTKlewsgql---gggred 117
EDV98627             34 IKDRQSHLLASKNRLQMLPDKGRRIRESYEKLLAEIHSRDEVEATAKLLGELNIASKGKITLNNlewqgrts-dpdsnas 112
XP_001999387         34 MRDRQSNILASKKRLESLPDKGRRIRESHEKLLAEIQRRNDVEATANLLGELNIASKGKVTLNNlewhgkts-pgksdvt 112
WGS:AANI:GJ22715-PA  34 IKDRQSNLLASKKRLQSLPDKGKRIQESYEKLLAEIQRRNDVEATANLFGELNIASKGKRTLNNlewhgraa-vdssnls 112
WGS:AAQB:GK13803-PA  40 MKERQGKFLTFKKRLDQLPDKGRRLKESYDKLLDEITRRDDVEAAARMLSELNIASKGRVALDNlewngkm---tddhva 116
EDW38512             38 IRDRQSKFLSFKKRLLQLPDKGRRLQESYDKLLDEIRRRDDVEATAQMLSELNIASKGKIALNNlewngreivdegahve 117
XP_002043333         38 IKDRQSHFLSFKKRLHQLPDKGKRLQESYDKLLAEIRRRDEVEEATRMLSGLNIVEKGKIALNNlewngrnt-degahvd 116
WGS:AAPP:GF16542-PA  38 MRDRQAHFLSFKKRLLQLPDKGKRLQESYDKLLDEIRKRDEVEQATRLLSGLNIAEKGKVALSNlewngrta-degahvd 116
XP_012657417         91 -EvdVNADKAQNSDQILDTSSLV---PGSSSVDNIKSSQTTSqKQELGHPTHRGDEETPEA------ECTVNECPASRnT 160
EGI69710            106 kIidLDSDDEE--DPLKILAQPTgtgVHKKKIIHMVPEENLIkPEDIAEIETFKTD------------------------ 159
EDS29103            118 dG--VDSDDEEETDPLKILAQST---HTEKVVLVAKPEPSLItEQDLKDIEELKQEQQVE-------------------- 172
EDV98627            113 dL--LDSDDEQEMDPLRVIAQGS---LHQRQVKILPPHATLItHEDLAEIESFR----LDSldsfrtDQSASSSCSGQaD 183
XP_001999387        113 dL--LDSDDEQDIDPLRIIAQGT---MHQRQVKVLPPPATLItPEDVVDIASFRQEQPSDSldssqtNESASS--SGQ-D 184
WGS:AANI:GJ22715-PA 113 dL--LDSDDEQEMDPLRVIAQGT---MHQRQVKVLPPPATLItPEDVADIASFRQT--PNSldstltDQSASSSLSGQ-E 184
WGS:AAQB:GK13803-PA 117 dI--LDSDDELEMDPLKIIAQGT---MHEKKVKVLPAEVTLItAEDLAEIETFKGASTSPD------------------- 172
EDW38512            118 dI--LDSDDEL--DPLRIIAQGT---MHEKRVKVLPPPESLItAGDLADINTFKKT--ADSpdsaleGQSATS------- 181
XP_002043333        117 dI--LDSDDEVEMDPLRIIAQGT---MHEKKVKVIPPPTSLItADDLADIEEFKKP--TDSpdsalaGHSDTS------- 182
WGS:AAPP:GF16542-PA 117 dI--LDSDDELEMDPLKIIAQGT---MHEKKVKVIPPSASLItAEDLAEIEDFKKP--TDSpdsalhDHSDTS------- 182
XP_012657417        161 ARVPSSSAASEHFPGHCVSRQAEDNFSSSD-------SLFIDKFQRITIEDQGEHNSEENTSAENLTglsglcsgtqkKP 233
EGI69710            160 --------------------------------------LLDTEHVKYIVDKVE---KVQEVKKREPF-----------KP 187
EDS29103            173 ---CAPAELIEVD----VAKSVGKLSSILEkrqqavvNELYDGHAIYICNKER------STAQKSKY-----------LP 228
EDV98627            184 GSNAVAAEIIEIDVVTLVGKPPATM---------------LEQHALYLIEKTE---LQATATEREKF-----------KP 234
XP_001999387        185 DSKIIPAEIIEIDVGKLVGNRPTEAT--------------LEQHALYLIDKTE---LH-AVKDREKF-----------LP 235
WGS:AANI:GJ22715-PA 185 CSKTIPAEIIEIDAATLVDKHSPGTT--------------LEQHALYLIEKTE---LPVSATAREKF-----------RP 236
WGS:AAQB:GK13803-PA 173 --STVPADLIEVKLSRLALTKESNDSAPAP-------TLPLEQHALYLIDKTEHQRSDNDPPVREKF-----------KP 232
EDW38512            182 ---SIPAEFVELDACLVAAKYPQESRS----------YPPVDQHSLYLIDITE---PKERSAGREKF-----------RP 234
XP_002043333        183 ---SLPAEIVEIDASQVAAKLSKEL--------------PPDQHALYLIDKTE---TNVNTP-REKF-----------MP 230
WGS:AAPP:GF16542-PA 183 ---SLPAEIIEVDASIVAAKLGKEE--------------PLEQHARYLIDKTE---VNINPSAREKF-----------KP 231
XP_012657417        234 HymevlemRAKN 245
EGI69710            188 Y-------KTTK 192
EDS29103            229 F-------RTTK 233
EDV98627            235 F-------RTTV 239
XP_001999387        236 F-------RTTV 240
WGS:AANI:GJ22715-PA 237 F-------RTTI 241
WGS:AAQB:GK13803-PA 233 F-------RTTV 237
EDW38512            235 F-------RTTI 239
XP_002043333        231 F-------RTTK 235
WGS:AAPP:GF16542-PA 232 F-------RTTV 236
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