7AS8


Conserved Protein Domain Family
RqcH

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COG1293: RqcH 
Ribosome quality control (RQC) protein RqcH, Rqc2/NEMF/Tae2 family, contains fibronectin-(FbpA) and RNA- (NFACT) binding domains [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 440904
Aligned: 280 rows
Threshold Bit Score: 273.254
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7AS8_0         1 MSFDGMFTYGMTHELnEKIMGGRITKIHQPYKHDVIFHIRAKGK-NQKLLLsaHPSySRVHITAQAYENPSEPPMFCMLL 79 
EHR76108       3 ATMSGFDLRAVAQEL-DVFAGAYVKKAYMPHYEQIVLRINPKEQdQFDLVL--VRG-SRIYTSQRDRPMPMTPPPFAMVL 78 
WP_010917693   3 DKESSLDFYAFTGIYrERLVGSFVKKVYQTGPDDFLIQLYRSDLkRFDMLV--SLK-KGIFFK--SEETPDTASQTAMVL 77 
WP_010901821   3 DKESSIDFYAFVNIYrDRFVGSFVKKVYQVGPDDFMVQIYRSDIkRMDVLI--SLK-HGIFFK--TVETPETATQTAMVL 77 
WP_015492984   3 KEMSSFDVSSVVREM-AILEDAHMDKIYQWGEGNVLFRINTKNDgKADLFF--KDK-KWLFLSPDRPETPETPTSFATFM 78 
WP_020448059   3 DEMNAFDILAMTSEL-QAIVGGYVDKIFHWDKRNVLLRVNSP-DgRKEVLL--KDL-KWLYIAPGKPDIPDIPSEFAVNL 77 
WP_048111109   3 KEMSSFDVRSIVSEM-ASLEGAHIDKIFHWGAGNVLFRLNVQGDgKRELFF--RDK-KWLYLSPTRPETPETPTSFATFL 78 
WP_066073239   3 KEMSSFDVSSLVTEM-AALEDAHLDKTYQWD-NNVLFRINAKGNgKVDLFF--KDK-KWLFLSPDRPETPTTPTSFATFM 77 
WP_015505481   3 KEMSSFDVRSVVTEM-AALENAHMDKIFQWGAGNVLFRINTK-NgKEDLFF--KDK-KWLFLSPDRPDTPVTPTSFATFL 77 
WP_021789816  42 DKESSVDIYAFVNNKrKDLQDSFVKKIYDLGGGKFIFQIHSPTLkKGSFYI--DVK-KGICLM--DAERGQDAGNLAMFL 116
7AS8_0        80 RKHIEGGFIEKIEQAGLDRIMIFHIKsrneigdeTVRKLYVEIMGRHsNIILTDaAENVIIDGLKHLSPsmnSYRTVLPG 159
EHR76108      79 RKHLKNARMTGVRQLGFDRVLGFDFDtk-----hGSYHLYVEVFRDG-NIILTD-QEGVIIQPLTHASY---AGRTLKKG 148
WP_010917693  78 RKTISDRRIVSVEQVNFDRVVKFVFH--------TGQALILELFRDG-NLIATD-GD-KITFVLKPRRW---RNRDLEVG 143
WP_010901821  78 RKTISDRRIVGIRQINFDRVVEFTFH--------TGQKLILELFREG-NLIATD-GD-RITFVLRPRKW---KNRDLEVG 143
WP_015492984  79 RKYLTNARIGKASQIGFDRIVTLEVFka-----dADYQIIFEMFGGG-NVLLV--QDGKIVNCLTQRTF---RDRATRPG 147
WP_020448059  78 RKHLSNLRVVKVSQREFDRIVLIDLEra-----eAKYQLIIELFSGG-NLILV--SEGKILNSIISRKW---RHREVRPG 146
WP_048111109  79 RKYITNARIGKTTQAGFDRVTVTEVFks-----dGEYRLIFEMFGGG-NVLLV--QDGKIVNCLTHKTF---RDRATRPG 147
WP_066073239  78 RKYLTNARIGKTRQVGFDRIVIMEVFka-----eADYSLIFEMFGGG-NVLLV--QDGKIVNCLTQRTF---RDRATRPG 146
WP_015505481  78 RKYLTNARIGKTRQIGFDRIVEMQVFka-----eGEYLLIFEMFGGG-NVLLV--QDGKIVNCLTQRTF---RDRTTRPG 146
WP_021789816 117 RKKFMDKKIKAIYQINFDRVVRVDFY--------NGSSFVMELFRDG-NLIVLQ-DD-VIEYALNPREW---KNRKIIRN 182
7AS8_0       160 QDYKLPPAqdKISPLEASEDDILRHLSFQEGRLDKQIVDHfSGVSPLFAKEAVHRAGL-----------ANKVTLPKALL 228
EHR76108     149 VVYQPPPA--AMDPHELDVATLSELFSTSDRDLVSTLGGK-ANLGGTHANAVCDLAQLepnma---tqdaNVEDVHTALQ 222
WP_010917693 144 AIYI-PPS--SSDPTKMTDEEFVNTVRQSKANAVQTLATR-FNLGGDLAEEVLFRIGLpkdgav-ddlenRANDVRRSLA 218
WP_010901821 144 GTYQ-PPS--SFDPSSASPEDMSKIISGSSANIVQTLATR-LNLGGELAEEILYRAGIdketpa-rdaagRSADIRSMLD 218
WP_015492984 148 EDYVMPKE--RFNPLAATEEEFSDEFRTSEGDTVRTLATV-TNLGGQYAEEVCARSGVdktlpaaeqgdGEIKSMYEALH 224
WP_020448059 147 VEYAFPQT--KFNPRNMDYGSFSQTVAASSSDAVRTLATE-INIGGQYAEEACLRAGImkntkaaelteENIRTLYDQIE 223
WP_048111109 148 EEYIMPKS--RFDPVISSLDDFKGVFRTSQSDTVRTLATV-VNLGGQYSEELCKRSGIdkskpspevgdDDLAKMYSSLR 224
WP_066073239 147 EDYVMPKE--RFNPLTSTEEEFSRVFRTSESDTVRTLATV-NNLGGQYAEEVCKRAGCeknvpaaevtdEALSQMYKAMN 223
WP_015505481 147 EEYVMPKE--RFNPLTSDEDSFKNLFRSSDSDTVRTLATV-NNLGGQYAEEVCKRAGVdktvpakdaddASVHALHSAVM 223
WP_021789816 183 EKYI-PPS--LVDPLSLKSENKIEILEKSKASIVQTMATR-FNLGGELSEEILNRAGIdknlda-kqctdLIGQIDEKLN 257
7AS8_0       229 ALFAEVKEhRFIPNIT-T-VN--G------K------------------EYFYLLELTHLKG-EARRFDSLSELLDRFYF 279
EHR76108     223 TLLGHLg-eQRQGILLmKpSDemGvealeqKaasmeanglrdrffeahaSEATPTILPSHAGmAQAKFATLCEAVDAWKG 301
WP_010917693 219 EILQES---LLNSAYYyE--Dq---------------------------GTVSPVPMKHFGEy-tRKFDDFNEGLVFLLS 265
WP_010901821 219 ELLKES---LANRSYYyK--Sq---------------------------GLVSPCEMKHFGD-PDRIFDDLNEGLLFVLT 265
WP_015492984 225 AIVEDIKE-HPQPTVFrY--D--G------Ki-----------------EDIAPVDMKVHDGcEKQPYDSISKAIGAFIA 276
WP_020448059 224 LMFSEAQN-SISAREIiI--N--E------El-----------------EDVSPIPLKQHEGfETVQYENFSTAIHHYVQ 275
WP_048111109 225 EIVDRVIK-NGEPTVFrK--D--G------Ei-----------------VDVAPINLKIYEDtEPEKVQSMSLAIDALLK 276
WP_066073239 224 DIVSQINV-KSQPMIFrR--D--G------Ki-----------------EDIAPVDLQIYEDcEKESAETMSLAIGKLMA 275
WP_015505481 224 EIADYVMR-EPHPTIFrQ--E--G------Ki-----------------VDIAPMDLHIYEDcVKEPMPTISEAIGKFMG 275
WP_021789816 258 ECLRETe--ENKGYFY-E--Ee---------------------------QLVSPIRLTFLNRePDRIMEDFNDSLQMMME 305
7AS8_0       280 GKAerdrvkqqAQDLERFVV---------NERKKNANKIKKLEKTLEY-SENAKEFQLYGELLTANLYMLK-------KG 342
EHR76108     302 AHDag----alARREAEKLDiaapgrghsTDVERLERRKVQQEKALSGfSKKIEKQQMIGHTIQNNWTHVEslliqvtEA 377
WP_010917693 266 MSP--------QEE---------------ESEDPIQRRINSQMKSIEEfGKIAEKYRSYGSQIMQNLQTVEmaikdarSG 322
WP_010901821 266 LSK--------DEA---------------EFEDPITRRINSQKKSIEEfEKIANEKQEIGRAIMERLQEIDgairsarSG 322
WP_015492984 277 EAA--------MQQKVERTD---------PEIEKLKRRIEKQQETVDEyTVNAERLKTQADSLYTEYKKVSellavlgEQ 339
WP_020448059 276 NIR--------NDEPQE--D---------KEVSRLKRLYTRQKEAIDAqLAVAEDYSKQAEAIYSQYSDVDaflkkfsKI 336
WP_048111109 277 EMI--------VAEEEAYVD---------PEMEKLKKRIQKQTETVDEyKMESEDLKKRADAIYIEYQKVNdllnvlgKK 339
WP_066073239 276 ETA--------ATEKKEFKD---------PEIEKLKKRIEKQTETVQAyRQSAERLKAQADALYTEYQKVTellkvldEQ 338
WP_015505481 276 ENE--------AEEQREFVD---------PEIEKLKKRIEKQKETVDAyRVEAERLKAQADSLYTEYQKVSelltvlgEQ 338
WP_021789816 306 TEI--------KDT---------------PENLRIRRIVENQEKTIEEyRKASETSREIGVIISSHFQTMKkvlqhlkTS 362
7AS8_0       343 DKQ---------------------------AEViNyydeespTITIPLNPNKTPSENAQAYFTKYQKAKNSVAVVEEQIR 395
EHR76108     378 IEAkgwkevksmaksipwivslnpaersflSVLpDeng-epkGPQATLSIDESVHQNAQRFFTAARKQKDKTKGAVDALE 456
WP_010917693 323 NYPsdkmnk---------------atkhisLKL-G-------EEDIDIDYTKSAGENANRYFDLSKDYRKKIEGAKKAIE 379
WP_010901821 323 NYAgnidra----------------rkvitVDM-D-------GKPVEIDYTVSAGENANRYFSQAKDYRRKIEGAMKAIE 378
WP_015492984 340 SKKlswekltegalkipyvayidpskntvaVRI-G-------LLEIELDYTKNIDANASDIYAKGKEQSEKAANAMKALN 411
WP_020448059 337 VEGktwdeiretvkphsviseidpknhtmkVTV-A-------ERQVLLDYTLSIEGNANMLYSLSKDARAKAKGAQDALA 408
WP_048111109 340 SKEltweklaegarkipyvmnidpsknivtASV-A-------GLKVTMDYTKNIDANASDIYQKSKDIYEKAKRAEDALR 411
WP_066073239 339 SKKlswekltegalkipyvdyinpeklivaVKI-G-------YLTIELNYTKGIDANASDIYAKGKTESEKADNAEKALT 410
WP_015505481 339 CKKlswekltegalkipyvsyidpsknivaMKI-G-------ILEVELDYTKNIDTNASEIYARGKEQNEKADNAQKALD 410
WP_021789816 363 DQErlsfdgfviev-----ksknkaeksaeITF-N-------ENTFKLFYDRSVGENMTSYFDSSKDYLERIEGAKIAME 429
7AS8_0       396 LAQEEIEYFDQliqQLSSASP-RDISeireelvegkylrpkqqKGQKKQKPHNPVLETYESTSGLTILVGKNNRQNEYLT 474
EHR76108     457 DTLLQLQRAQK---KEAKQQAtGKLN-----------------KIKRSKRLWFEHHRWSMITGGHLLVGGKDAKGNDSIV 516
WP_010917693 380 EAEQERIKLQE---KKVK--------------------------SVNRRIFWFETYHWFISSEGYLVIAGRDAKSNEKIV 430
WP_010901821 379 EAEKQRLTEMQ---KAEK--------------------------KKRRKVFWFETYHWFISSEGYLVIAGRDAKSNEKIV 429
WP_015492984 412 DSREELGKKEK---GFEKVKA-AELS-----------------KAAPTKRFWFEAFKWFITSEGRLALAGRDTHSNDSVV 470
WP_020448059 409 DTEKKLAKRVK---ETEKDAS-NSKT-----------------AAVKTKEYWFERYKWFITSNGHLVIAGRDAHSNDKLV 467
WP_048111109 412 ESMTELDKKQK---GIDKAKA-LAAG-----------------KVQPTKQFWFERYKWFITSSGKLVIAGRDAHSNDNVV 470
WP_066073239 411 DSQAELEKKQK---GFDKKVA-AELS-----------------KAAPTKRFWFETFKWFITSEGKLVIAGRDTHSNDSIV 469
WP_015505481 411 DSVAELEKKQK---GFDKKVA-AELA-----------------KAKPTKRFWFESYKWFISSGGRLVIAGRDTHSNDQVV 469
WP_021789816 430 NSIKGIQEQQV---K----------------------------KKKDRPRFWFETYHWFFTPANHLVISGKNTDTNEKVV 478
7AS8_0       475 TRVAARDDIWLHTKDIPGSHVVIRSS-----------------------------EP-DEQTIMEAATIAAYFSKAKDSS 524
EHR76108     517 KKHLSGQDRYLHADLHGAPSCSLRATqgfvvdqhkpahipadvpafrivdklgdeRI-TEEKLLEAATMALCWSRAWAGG 595
WP_010917693 431 KKHLKEGDLYVHADMYGAPSTIIKSEg---------------------------kPMpGEDTIRQAAAFAICFSRAWPAG 483
WP_010901821 430 KKHLQEGDIYVHADMYGAPSTIIKSSg---------------------------kQPpGEATLREAASFAVSFSRAWPAG 482
WP_015492984 471 KKHMKEKDIYAHADIHGAPSVVLKEg----------------------------lSA-TPDEFREACWFALAQSKAWTAG 521
WP_020448059 468 KKHLKATEKFAHADIHGAPSTVIVNg----------------------------aEA-DEEEMEEVCAFALSHSKAWMTG 518
WP_048111109 471 KKHLKEKDVFVHAEVHGAPSVILKEg----------------------------tGA-TPEELREACVFALTQSKAWVAA 521
WP_066073239 470 KKHLKDPDVYVHADIHGAPSVILKDg----------------------------sKA-SDQELREACWFALAQSKAWMAG 520
WP_015505481 470 KKHLKEGDVYAHADIHGAPSVILKDg----------------------------lKA-SEEELREACWFALAQSKAWMAG 520
WP_021789816 479 KKHMGEKDIYIHADMYGAPSTVIRNEdn--------------------------aEI-TEEEITEAAAFAVSFSRAWQNG 531
7AS8_0       525 --SVPVDYTKIRHVKK-PNG----AKPGFVTYDSQHTV-FVTPdadtviKLKK 569
EHR76108     596 gaHGTVYSVKPAQVSKtAQTgefvGKGSFIVRGQRQWFkDLDV------QIGI 642
WP_010917693 484 iaSGTAYWVYPSQVSKtPESgeyvSTGSWIIRGKRNYVtNLKL------ELCI 530
WP_010901821 483 iaSGTAYWVYPSQVSKtPESgeyvATGSWIIRGKRNYItDLKL------ELCI 529
WP_015492984 522 spEGGAFWAYPDQVSKtPNAgefvPRGAFIIRGKRNWEyHIPL------EMGI 568
WP_020448059 519 aqEGTAYWVLPDQVSKmPQSgefvPRGAFVIRGKRNYIyHLPL------ELAV 565
WP_048111109 522 ltEGAAFWAYPDQVSKtPNPgefvPRGAFIVRGKRNYEhHLKI------ELGI 568
WP_066073239 521 ssEGGAFWAYPDQVSKtPNAgefvPRGAFIIRGKRNWEyHLPL------ELAV 567
WP_015505481 521 saEGGAFWAYPDQVSKtPNAgefvPRGAFIIRGKRNYEyHLPL------EMGI 567
WP_021789816 532 ltSGSAYWVSPLQVSKtPESgqyvRKGSWIVRGKRNYLfNLPL------KLSI 578
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