2V7Y


Conserved Protein Domain Family
DnaK

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COG0443: DnaK 
Molecular chaperone DnaK (HSP70) [Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 440212
Aligned: 748 rows
Threshold Bit Score: 159.218
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2V7Y_A         4 II------GIDLGTTNSCVAVL---E-GG---E-----------------VK--VIp---nPE----G----NRTTPSVV 40  
WP_012069756  11 RV------GIDLGTTNCVVSYV---P-VA---Dhsnana-----pallpiPQ--VM-----AD----GsvqeFTYLPSAI 61  
WP_012609911   9 IV------GIDLGTTNSALSYV---D-LT---Gkntask-----ikmfrtPQ--VF-----AP----GelarLSVLPSFL 59  
WP_032124101   8 II------GIDLGTTNCTLAYT---P-IQ---Aeghavps----itqaelPQ--II-----GA----NtqgaPLSLPSFI 59  
WP_013907166   5 VV------GIDLGTTNCALAYA---D-LK---Etgpeln-----vkvfqiPQ--LV-----GA----GrlgkRETLPSFL 55  
WP_012910889  22 VV------GIDLGTTNSAVCYV---D-CE---Rntsrv-------evlaiPQ--FT-----AA----NvvekLDTLPSFL 70  
WP_015217826   7 SLnycnyyGFDCGTTNWRIFQVsgtE-SN---Qads-----------isePQ--PVslticDSa--------RHSLSAAL 61  
WP_011682755  14 KI------GIDLGTTNSALAYI---D-ER---Eaedrdfp---plhifetPQ--LV-----AA----GrvepRRTLPSFL 66  
WP_129190469  21 AL------GIDLGTTYTTVTRT---EwSGvpgDt----------------PTldVVp---iRQwttaGld-sVPIVPSVV 71  
WP_077024249  17 VV------GIDLGTTNSAVCYV---D-TS---AtetsdnhdtwdvrtlkvPQ--LV-----AP----GqvehRDTLPSFH 72  
2V7Y_A        41 AF-KNGE----------------R-LVGEVAKRQAITN-----P--NTIISIKRHMGTDYKv------------EIe--- 80  
WP_012069756  62 YVlASDEigkidpvlpwrhhdkeR-IVGVGALALGQRR-----Ag-QLVQSAKSWLSHRQVdrrsai-lpwaseFP---- 129 
WP_012609911  60 YLpGQYDvdrenlkl-pwkdeeiG-IVGTFAREQGSKV-----Pg-RLVSSAKSWLCHSKVdrtapilpwnadkEV---- 127 
WP_032124101  60 YYpLEEElsarvaai-ewdlsrpY-AIGAFARDRGSEL-----Pa-RLVASAKSWLCHTGIdrrqailpfeseeIA---- 127 
WP_013907166  56 YLpGELEaqedlgl--pwdnsrrF-AVGTYARDHGALV-----Ps-RLVSSAKSWLCHGGVdrtakilpwgsgdDV---- 122 
WP_012910889  71 YQpAADRaalgklp---wnddsqP-IVGAMARDAGAIS-----Ag-RVISSAKSWLCHRGVdrladvlpwqaapDV---- 136 
WP_015217826  62 LLnEDSQ----------------IlACGERAYEDSSIGv-------NLLDAFKLCFGNnq-------------tvIasdp 105 
WP_011682755  67 FLee------------------gE-PVGVYAREQGALV-----Pt-RLVHSAKSWLSNPDVdrtakilpwdsqeTG---- 117 
WP_129190469  72 AVtNSGS----------------V-VVGLEATESALNGelspiPgkNYFAATKNEIGlrr-----------qypRAph-- 121 
WP_077024249  73 YQpAAGEfsdgelqlpwsnafagH-FVGTLARDHGIHV-----Pg-RMISSAKSWLCHPGVdrtagilpwqggdDV---- 141 
2V7Y_A        81 gKQYTPQEI-------SAIILQYLKSYAEDYL--G--E-PV--TRAVITVPAYFNDAQRQATKDAGRIAGL--------- 137 
WP_012069756 130 -KKLSPLEA-------SKILLLHIKQSWNHRf----aDaPLesQSIALTLPASFDEEARALTLEAAKLAGL--------- 188 
WP_012609911 128 -QKVSPVFA-------SGSYLKHLRIAWNHQa-kGvdEkFLenQFVIITVPASFDEVARDFTMEAARTAGI--------- 189 
WP_032124101 128 -SKISPLEA-------CSEILRHLREAWDF----NksEaPFvdQHILITVPASFDPNARQLVQEAAEKAGY--------- 186 
WP_013907166 123 -EKVSPVEA-------SARYLEHLKEAWNYEIasDdpEkRLenQLVILTVPASFDEVARELTLQAAQMAGL--------- 185 
WP_012910889 137 -ERMSPVEA-------SSRYLAHIRAAWNH----QfkGaPLeeQEIVLTLPASFDEVARELTISAAQRAGL--------- 195 
WP_015217826 106 nRRYTHVEAlsytgklLSKVLDRLLEEKQNFL--G--N-N---NQFIFTHPVHWGKTKNNGEIEGTILNDFavtirayfp 177 
WP_011682755 118 -RVLSPVEV-------SARFIAKFRDEWDKa-----kGiPLaeQDIVLTVPASFDEEARELTVMAARDAGI--------- 175 
WP_129190469 122 -gLQSPVDI-------AAHILKFVLAGVRESFp----D-DVw-DRVVVTVPASFQLGQRADTVEAATRAGL--------- 178 
WP_077024249 142 -DRLSPVEV-------SSRLLAHVVDVWNH----QfpDePLadQTVVLTIPASFDEVARNLTIQASQKAGL--------- 200 
2V7Y_A       138 ----EV--ERIINEPTAAALAYGLDK--------Ee--DQTILVYDLGGGTFDVSILELGDGV-------FEVKATAGDN 194 
WP_012069756 189 ----ND--LYLLEEPQAACYHYISDdekl--aalVd--KKMLLVVDIGGGTSDFSLVAIQPTSakaksvsLKRIAVGEHL 258 
WP_012609911 190 ----GE--VTLLEEPLAAFYSWLVFHendwenyvKp--GELILAVDVGGGTTDFTLITLREVDgs---prFERIAVGDHL 258 
WP_032124101 187 ----PE--IVLLEEPQAAFYAWLHAHaknwrevlKv--GDCVLVVDIGGGTTDFSLIGVEEIEgn---ltLKRLAVGSHL 255 
WP_013907166 186 -----E--VILLEEPTAALYAWLSQNeknwyeklNp--GEHVLICDIGGGTSDFTVVEVREGQeg---pyLERIAVGDHI 253 
WP_012910889 196 ----PR--VVLLEEPQAAFYAWIAKHrdtwqaelKv--GQKILICDVGGGTTDFTLIRVRQDEtgq--iqLHRIAVGDHL 265 
WP_015217826 178 dqlhEN--IHFVSEPEAALLSLVQTKq------lQklvKGYSLIVDIGGGTTDLVAGQWTSEG-------LQDIRYFGAA 242 
WP_011682755 176 ----EK--LTLLEEPAAAFYSWIANNlaasrkklFd--GQIVLVCDVGGGTSDFSLIRVSREGdl---vnFTRTAVGKHL 244 
WP_129190469 179 ----SVlpNDLLDEPVAALLTRMATApt-----tQg--THRVAVVDFGGGTCDVALLEHTQRAhgg--vdLEFRGTSRYC 245 
WP_077024249 201 ----PR--VLLIEEPQAAFYAWIDRHrgdwedrvQp--GQKILVCDVGGGTTDFTLIRVKSGAdnk--vlFHRVAVGEHL 270 
2V7Y_A       195 HLGGDDFDQVII-DYLVNQFKQEhGiDlsKDK------MAL-QRLKDAAEKAKKELSGV---TQ----TQISLpfis--a 257 
WP_012069756 259 LLGGDNLDQALA-FQLDPKQi-----Sa-LSA------TRL-AALVQQTRQAKETLLGKdapES----LSITVlg----- 315 
WP_012609911 259 ILGGDNMDLALA-RKTEASFKKApS-Qs-LNA------NRW-QALCHQCRQAKEAILGGe-vDK----KTVTLmg----- 318 
WP_032124101 256 LLGGDNIDLGLA-YLAKQKLEEQ-G-Hl-IDA------WQL-QALVHQCRQAKEMLMGEkppAK----IDITVlg----- 315 
WP_013907166 254 LLGGDNIDLALA-KLAEKKLP---T-Kr-LDF------ARF-QTLTFLCRELKERLLSPdgpEE----DAVRLtg----- 311 
WP_012910889 266 ILGGDNFDLALA-KHLEEKLAAT---Kg-LDA------RQW-DTLLRASRSSKEELLSQaspTE----RTISIas----- 324 
WP_015217826 243 -YGGNHFDQAIA-DYIANKFKldelqQlsLD-----------RQLRYYGRKFKENLSQQ---ARinyhQPVNLiv----- 301 
WP_011682755 245 LLGGDNLDLTLA-WLVENKL----G-Vp-LSI------RQR-SGLRRQCSAAKEKLLNDpnlKS----VEITVlg----- 301 
WP_129190469 246 RLGGSDLDRAIAvEHLLPRLAKAnGvn-aSDwdyagkaAVLiPSLAPVAEDLKIKLSGAm---R----RRVRLgqpysdl 317 
WP_077024249 271 ILGGDNLDLALA-YFIEGRFREE-GvSq-LTP------RQW-SVLVRVARQVKEALLSPdapNQ----FTVSLpg----- 331 
2V7Y_A       258 nenG---------PL-H----L---E-MTLTRAKFEELS----AHLVE---------------RTMGPV--RQAL----- 293 
WP_012069756 316 --gGsr-----liGG-S----Q---K-FDVSREALLEQIrngfFPLVKsd------------dKVQKS---DYAMhtlgl 364 
WP_012609911 319 --eGrg-----liAN-T----L---S-ATLTRDQVEETIldgfFPVVDsd------------sQAPTAR--KGGItefgl 368 
WP_032124101 316 --rGsk-----liGN-T----L---K-TELTQKEAHQFVldgfIPLIGpd------------eRSPVER--RTGIqqigl 365 
WP_013907166 312 --rGra-----liAD-T----L---V-ARITRDEVLSLIlkdfFPEVTfn------------qALARVEsvPRGMrdwgl 363 
WP_012910889 325 --gGsr-----liGG-S----L---Q-TTITRDEAATLLvegfFPKVPrd------------aRPQAR---RSGFqefgl 373 
WP_015217826 302 -----------vlAApTetnvLr--QaISLTCAEFEKIT----TDGQK---------------YLHDSL--LASL----- 342 
WP_011682755 302 --tGss-----liGK-S----L---K-TEILREEALELAlegfLPVSQrg------------eLPKDEK--RSLFrelgl 351 
WP_129190469 318 vvhGssdfavtlrGA-Ty--hLdhsQ-ISLSTAEFDRIL----GPYLDaerlkprfgeyfeqgSVFAPL--LEVL----- 382 
WP_077024249 332 --sGsk-----liGG-A----L---Q-TQVTKQQVTDVLlegfLPQTTft------------dVPQSN---QSGFrefgl 380 
2V7Y_A       294 ---QD-------AG-LTP-----AD--I-----------------DKVILVGGSTRIPAVQEAIKRELGK-------EP- 330 
WP_012069756 365 pyeSDpaftrhlAAfLQQhgaviEAatgs-------------impDAVLFNGGLFNSPVLKARLLEQLNTws----sKPi 427 
WP_012609911 369 pyeQDpavtrhmCKfLERhaqsvKD--Mlgke---------vpfpDLLLFNGGSLKPEVIQTRIREGVKYwfk--sdRLp 435 
WP_032124101 366 pyvQDpriscqlAKfLSMtgeseTA--Gmdqf----------impTAVLFNGGTLKAAALRKQLMALLNRwakelkkPAv 433 
WP_013907166 364 pyaREqaitrhlGAfLYKnkiekV---------------------EVILFNGGALKPPIFRERLKEEVARwfn---lnSl 419 
WP_012910889 374 pyaADpaitrylAQfLARhryadVD--PpadpqaiptppldpakpDLVLLNGGVFSSPLLVSRLLETIGEwftgdraTPw 451 
WP_015217826 343 ---EE-------ME-LNS-----GD--I-----------------GQIILVGGGARLFIVSNILREIFGN-------SIp 380 
WP_011682755 352 pyvSDpavtrhlNEfLEPtgq----------------------ipDAILFNGGFFIPEILRERVADVVAHwygr------ 403 
WP_129190469 383 ---ER-------TG-WSS-----ES--L-----------------DELLLAGGSSALPPVADALANQLGV-------SVs 420 
WP_077024249 381 pyaADsaitrylAEfLRThaetaAEneMlrddd-------haarpDIVLFNGGLFESALLKQRMTEVLSSwfsegdrEWe 453 
2V7Y_A       331 ----H-KG--VNPDEVVAIGAAIQGGVIA--Ge-V-KdvvlldV---TPL--SLGIETmggvFTKLIE-------RNTTI 387 
WP_012069756 428 l--aC-SA--DEPNDAVAKGAAMYLNALA--GesT-R------IesgVAHslYLKVGEn---------------eFVGIL 478 
WP_012609911 436 g--vL-EN--PDLDLAVARGAAYYGLVKS--Glgvkvgsgsargyylevsgaegqngkgkalcllergveegtrinlsqr 508 
WP_032124101 434 q--eL-PD--ADYDYAVSRGAVYYGVARL--GqaI-R------IrggTSRsyFVGVEE----AAPAVPgispplrAICIV 495 
WP_013907166 420 k--vL-ET--TSLDLAVAIGAAYYGLVKQ--GlgI-R------VgggLPRayYLGVEE----GDKAk--------AVCLA 473 
WP_012910889 452 qprlL-DN--DRLDLAVARGAAYYGLVRR--GlgV-K------IaasLARsyYLGLEGtp-------------pqAICLV 506 
WP_015217826 381 ----IiYG--DPPESTVARGAALWGMRSSllt--------kktI--------------------DILEe-----lVVNPL 421 
WP_011682755 404 rpeiF-EN--SDLDLAVARGAAYYSYVRS--Tgsgvlvrgglprtyyiglgdpkegkfsavclvprgaeegaaieidnda 478 
WP_129190469 421 y--vI-APerQERQTEVGIGAGLQALALAisGapLaRa---------MSGe-HLQMLAadgkWHDLIP-------ANQPL 480 
WP_077024249 454 p-liL-NC--ERLDLAVAQGAACYGMVSR--GigV-R------IsagLPRtyYLGVET---------------------- 498 
2V7Y_A       388 P------TSK---SQVFttaa-----dnqTT-VDIHVLQGe------------RPMA----ADNKSL--GRFQLTgi-pP 433 
WP_012069756 479 Pk------------------------------------------------------------------------------ 480 
WP_012609911 509 qfqvlanqpvsfqvysssyrsgdkagdiididdtltllppintviqfgkkgaqtqipveieahytevgtlslwcksvntd 588 
WP_032124101 496 PfgmeegEEReldNQEFal--------ilGEqATFRFFSHatpklsngvepeaGTIVrnwkQELTELhpIETLLDk---- 563 
WP_013907166 474 PkglkegEKLsl-pKTFkv--------ltNRpVKFPLYTSstrn------dslGDVVel-dENFAELppLSTTLKfg--- 534 
WP_012910889 507 PgsaqpgETItlkQPALel--------lvSQpAQFPLFVSslrl-----adraGEVLpidpEQMSALppIRTALKt---R 570 
WP_015217826 422 Pk-------------------------------------------------------------------NEVIINds--- 431 
WP_011682755 479 lqlvanrpvsfrlyssltrtddqlgqvlefdvadpnlhvhaplnavirfgkkaeerlipvklgarlteigtleswceski 558 
WP_129190469 481 Pfp--------egPVDYlsgsvsgsitsadegLKVQLRKGp-------------------------L--TVFTEEvplpA 525 
WP_077024249     --------------------------------------------------------------------------------     
2V7Y_A       434 APR-GVP-QIEVTFDIDANGIVHVRAKDLgTNKEQ-SITIKsssgl--seeeIQRMI 485 
WP_012069756 481 ---------------------------------------------------gTlkge 486 
WP_012609911 589 hkwrlqfqirkqeaapqvedaqvfeesvveevfskfnevfgkkkgelpperlpnvia 645 
WP_032124101 564 KEGdGKTtRVKLKAKVTELGVLELWCVAP-D-ERKwKLEFD-----------TREDR 607 
WP_013907166 535 rKSgLKEiPVRIEVLLSEVGVLETYCCSL-ETPHRwRLQFN-----------LRIQE 579 
WP_012910889 571 TRGeRGTiAVHLNVLLTEIGTLELWCSEA-EGERQwRLEFD-----------VRSAT 615 
WP_015217826 432 ----------------------------------qpAVIVQis--------tVypth 446 
WP_011682755 559 sdnrwrlqfelrkavkeqpaerkaaavvseqalkssldliesvfsptaksplppeev 615 
WP_129190469 526 GTSiGd--VFTVRTTMDTNQLVTLEIEFSn--RHRhTFQIErpgtyvsnpnvIREKI 578 
WP_077024249 499 -----------------EAGmnavclvpagtepgtdldppeqtfqlqtgrpvefpvl 538 
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