Conserved Protein Domain Family
C6_DPF

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pfam10170: C6_DPF 
Cysteine-rich domain
This is the N-terminal approximately 100 amino acids of a family of proteins found from nematodes to humans. It contains between six and eight highly conserved cysteine residues and a characteriztic DPF sequence motif. One member is putatively named as receptor for egg jelly protein but this could not confirmed.
Statistics
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PSSM-Id: 431108
Aligned: 29 rows
Threshold Bit Score: 110.016
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_003137814  30 FTCFLCGLTENCRYGLVEV-SGrTHNYRYKDEMYYMLDPFRNRNTvnerrltrtkantcsktsgsktasilDILVLGAIC 108
EFN87745       9 FACSFCSLKEHYDYKGTRP-PF-ARQLVYLEECYVMKDPFSLPSRg-------------------------EVLVLGGDC 61 
XP_003244737  58 FVCKNCNLTERYDCFNDHV-SF-NRKVGTKVDYYLARDPFSPRSKr-------------------------QFLILGSVC 110
XP_001900545  30 FTCFLCGLTENCRYGLVEV-SGrTHTYQYKDEMYYMLDPFRNRNVnerrltrtktdid-nkpsgsktanifDILVLGAIC 107
EFJ45950       2 FACSLCGFEAPFKHFGASL-PS-VCS--FLEEGWLAVDPFSIQAR---------------------------PVFLGAPC 50 
EFX74840      18 FQCALCGWSERYHGHGTSL-PF-ARGINFNEDAYVMRDPFVPYAQn-------------------------LYFFLGAPC 70 
XP_004343823  38 TQCSLCAHPVPYDYTGKTP-PF-APRVVFLEDVFAIRDPFAVAAQtaslaa---------------aslpkRCLAMGARC 100
EEH55089      21 FECKCCGIEINYEYKGRTP-PY-EPSIVFLEDGYFRRDPFADVKR---------------------------PLFIGADC 71 
XP_002111369  42 SRCNVCKLQLAYEYFGQRP-PFgKKTIALLENAYVIHDPFDADGS---------------------------HLILGSHC 93 
1_pfamImport   1 FTCDVCEVTFSYKFHGRYLdDLgIKDIELLEEAFVILDPFVPTKD---------------------------FLVLGGHC 53 
XP_003137814 109 SICGQPVCIGedCGVFYAKAFCIVCINREKAHFPKNFIEQID 150
EFN87745      62 STCGHAVCLG--CSIFYTKRFCPKCASSNMHNLPNKLHGKIS 101
XP_003244737 111 SMCDKDVCIKpeCSIFYSKFFCSICARKYISNFPTSIQEKIK 152
XP_001900545 108 SICGQSVCIDedCSVFYTKTFCIICVNREKTHFPKSFVEQID 149
EFJ45950      51 SACGRAVCTAeaCSVFYSKRFCRPCARSNAEAFPAAVRKAAP 92 
EFX74840      71 SACQRLVCAN--CSLFYSKRFCGECANKNVQHFPVEVQKKIH 110
XP_004343823 101 AECNRIVCMQatCSLFYQKRFCALCAKQWANCFPSQLKPDLE 142
EEH55089      72 NVCSRPVCAQptCSLFFTKRFCAACAKQYAEGFPLELRPDLE 113
XP_002111369  94 SECGAAVCVDqkCSLFYVKRFCCQCCIARNEDFPTEVQKEIK 135
1_pfamImport  54 SVCNAVVCVDrnCSLFYCRRFCRRCALSNSQEFPTAITKELK 95 
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