3CJM,3P09,4EWF


Conserved Protein Domain Family
Beta-lactamase2

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pfam13354: Beta-lactamase2 
Beta-lactamase enzyme family
This is the catalytic domain of class A beta-lactamases. It is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.
Statistics
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PSSM-Id: 463854
Aligned: 76 rows
Threshold Bit Score: 82.3223
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3CJM_A         53 GISYLDLE-----TGEQ---RSVNGQH-EFYTASTIKVPLTXLVADTVASGQ-KKWTDLIPYNAEeDYEeGTGIIAY--- 119 Enterococcus f...
BAH18702       38 GVYVNDLT-----DKQK---LSYNEEL-LFPYASTFKVINSALLIEKLGMNN---LDKEVKVSER-DIVlYSPIIEKykn 104
3P09_B         40 GIYTLNTD-----DKTN---IKYNESY-HFPICSVFKFLLVGAILDYDXHNQ-GFLDKKIPINQD-DI--GKLGYAPita 106 Francisella tu...
Q5NGZ5         43 GVYTINRN-----DWSN---FAVNASF-YFPICSTYKFLVVGAILKQSMTDN-KLLNQKIKISKN-QIVeYSPITRR--- 108 Francisella tu...
Q112T9        194 MITVCNLQre---------cLDLNGNKpPASAASLIKVPIAVALMQKVSKEN-ISLDTPVYVSRGnFTEdGSKI------ 257 Trichodesmium ...
Q5FIM3         98 QIVVQDL------NNSNrfaVVSNTNK-SHDANKAMKLFLLIALYENEQQGK-MGSKTAIKIKKS-DKAsGDRMFQVnm- 167 Lactobacillus ...
Q55G30         60 EWGVTDFK-----SFSI---LSENSQN-SQQTASTIKLWVLLSVFKDIEAGL-YTLEKQIECSTGl-------------- 115 Dictyostelium ...
jgi:Haur_3723  13 GQWSVDFR-----SCTGaiyYQYQPSL-QLPSASLIKLFLAWQWYTTNQPGFdVLISEQLIVDLD-----GSLAQAIgs- 80 
Q04F03         17 KSLDKQLQlsfylSNSEn-cFSFHGNR-VMPSASLIKLMIADYYCSNFSLADlQKQTQKISQGVG-----GSGVIQIldq 89  Oenococcus oen...
WP_015510117   15 ENYQTTLEmglwiGTPTeclVDYQSQK-SFSAASISKLVLYAYYLEQINEEK-IDPQQLIGVNAV-DLTgGAGVIRLfp- 90  Enterococcus c...
3CJM_A        120 -NIQpeYPLKTLQEYAITYSDNIAKNXLYDTLGgdaKAKREXYQRYLhktps-----------------------ieepq 175 Enterococcus f...
BAH18702      105 kN----VSLKMLIEAALLYSDNTANNLIIEELGg--LKEVEKRLSALgikgvnvnrkeva--------lnfydpkknedt 170
3P09_B        107 kNVGktLTISQLNYAAIL-SDSPASNILVRELGg--LQNLNKFIKKLgdndtiitadepe--------inytqphsnink 175 Francisella tu...
Q5NGZ5        109 -HINqiMTVKQLCQASMQ-GDNTATNILIEKLGg--LKNLNKFILSLadhatkvanlepk--------vnhvslttnenk 176 Francisella tu...
Q112T9        258 -RARkrYPLKTLVGEMIDHSSNIATNQLIDYLG---QPYINKVLKDDgykiirvnyklmgn------rirpknpgrgrnr 327 Trichodesmium ...
Q5FIM3        168 -----aYGVAYLREAMLK-GNKTASNALIRKIG---VNNVDSVAKRMgatqttiak---------------nfngssygk 223 Lactobacillus ...
Q55G30        116 ------ITVEQCIALMIGVSDNCATYSLTALTK---IESVNSLFSELgmndsqfiewcfstcvgysdpcpnvsggsgnnv 186 Dictyostelium ...
jgi:Haur_3723  81 -----kFSSDHMIYLMLNQSENNATNVLLAQLGg--IQAANSWLQQAgyqatrwgrvml---------dfqarqqgleny 144
Q04F03         90 ----kvLSLSDLISMMLSLSDNTAANTLIDIVG---LNSLSVWIKGHysatslsrkf-------------mdfsqkkdnl 149 Oenococcus oen...
WP_015510117   91 --qKkgWTISELLTAMIAVSDNTATNVLLDLVG---LPTLQAWIQEPeiqferymm---------------rpikdkenr 150 Enterococcus c...
3CJM_A        176 FSSEDALVILQKLY-----TEkatKPDYQAIYDSXKQSVF-HERXETPT------TQGKVAHKIGSy-------dEF--I 234 Enterococcus f...
BAH18702      171 ISAKNMSKALIKMLtg-dvLE---YKEQIFLIDLMKKNKTgTTLIKKGMd-----KKFIVGDKSGQga-----nyGV--R 234
3P09_B        176 TTPKAITKDIYKLAfg-niLD---KKHKDIFIKYLQDNNTgANRIAFSXp-----KDWIIGDKTGTc-------gQYaaT 239 Francisella tu...
Q5NGZ5        177 TTPKIMARDINKLAfsddiLD---KKHRLMFKQWLIASNTsNNRIAAEVp-----DEWEVGDKTGTcq------yGT--T 240 Francisella tu...
Q112T9        328 LTSNELTDMMVSIYnn-------eYPNSDVLIEALANQ---KDRLLGYAgleklpEAKWLGEKTGE-------------- 383 Trichodesmium ...
Q5FIM3        224 TTANDLAKTMIGLYqg-rvLN---RQHASRVLSTLASSKP-RPSLVNGI--------------SGGvya--------igD 276 Lactobacillus ...
Q55G30        187 LSSHDVIHGLTLLHqg-siLN---QTMTEMTYKYLLTAHG-WQPMIGYY------VPAPVAHKSGWlpadegfdpFT--E 253 Dictyostelium ...
jgi:Haur_3723 145 TSAEELTRLLHTMTd---aIAk-gGSMASTLVKSLVNSAS-DDKIAASLp-----PAVVCAHKSGEl-------aDV--E 205
Q04F03        150 TDANDAAHALRRLIe--------fPLTKRALLKQQSTNKFeLNFVESNN------QKIYFYNKTGE---------GSgiD 206 Oenococcus oen...
WP_015510117  151 LTPSAAAKLL---------LRcvkREEAALGFSPLNQQQF-QEGLAGNFaet-aqPACRIFNKTGRl-------dRI--E 210 Enterococcus c...
3CJM_A        235 HDXGI---LETP---HPF-ALAIFT 252 Enterococcus faecalis V583
BAH18702      235 NDIAV---VYKKqsnKPI-IVVVFT 255
3P09_B        240 NDVAI---IWPKn-qQPI-ALGILY 259 Francisella tularensis subsp. tularensis SCHU S4
Q5NGZ5        241 NDVAI---IWPDd-nRAV-IMAIFY 260 Francisella tularensis subsp. tularensis
Q112T9        384 NSRALgttLGFSingQVY-VMTVID 407 Trichodesmium erythraeum IMS101
Q5FIM3        277 NDFAV---AIVQgrgNAY-CISAWS 297 Lactobacillus acidophilus
Q55G30        254 NDEAI---VFSe--cGDYgASIMIT 273 Dictyostelium discoideum AX4
jgi:Haur_3723 206 HDAAL---IYs---aGMWdSLVIMA 224
Q04F03        207 HDAIIfryQNRQ-------ILAVLM 224 Oenococcus oeni PSU-1
WP_015510117  211 HDVAY---LQa---nETTiIIAAFS 229 Enterococcus casseliflavus
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