Conserved Protein Domain Family
ZnMc_MMP_like_1

?
cd04279: ZnMc_MMP_like_1 
Zinc-dependent metalloprotease; MMP_like sub-family 1. A group of bacterial, archaeal, and fungal metalloproteinase domains similar to matrix metalloproteinases and astacin.
Statistics
?
PSSM-Id: 239806
Aligned: 27 rows
Threshold Bit Score: 82.1191
Created: 22-Jun-2006
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
 
active site
Feature 1:active site [active site]
Evidence:
  • Comment:consensus motif: HEXXHXUGUXH U= bulky hydrophobic
  • Comment:coordinates zinc, contains catalytic Glu
  • Citation:PMID 8253063
  • Comment:Based on similarity to sequences with known structures.

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                      
ABG51092    81 QFPIKVYVEssdnd---------------------------esrsRQWVKTVVDAIWEWNIYl----PLQVVDSPe---- 125  Trichodesmium er...
YP_526977   40 TLTIPVCWEnpea-----------------------------fpvEEQAWVRKAVERTWEQE-----SLVRFTGWgecg- 84   Saccharophagus d...
CAE79162    29 GFVQNVYGEriswksdapv-----------------tmqlhssipDSMVPAILRAAETWERTag-rkLINIIQYPrysgp 90   Bdellovibrio bac...
YP_630894   29 TRTQCLYWTsnrvvwnqs------------------tygnpdtagDSEFDAIRASFQSWQDIfaecgNLTLVEGPrvder 90   Myxococcus xanth...
NP_633757   12 TYNGRYWHSgfaqvd------------------------kdssipSSWSNSLTQAMSAWNNAg---aNFFFYQIG----- 59   Methanosarcina m...
BAE55462    55 PVPQNFKHDpaaimvglgtevprwrpgsvikwtawrmgydsqddaNYAAAQLQQAAEEWNKLn---iGVTFEFVPla--- 128  Aspergillus oryzae
CAJ74546    43 KDTVTYLINttd-------------------------------gpSGSLDAILAAMQTWTDVd----TSTFVFIDggtts 87   Candidatus Kuene...
XP_388268   48 PTILRWYLNastfp--------------------------deeeaNFAAVALNQAAREWNNVn----FGVAVQQTtnk-- 95   Gibberella zeae ...
YP_501914  333 VTSVNYYINpg--------------------------------siIGSLTAIQNAANSWNGQs----SFKFNYAGtsstt 376  Methanospirillum...
YP_436624   41 GNAIKWNGNqttmyis----------------------ttsfpagSTWDSRLQNAMWHWNNVk----GSRFLYYVnrdtd 94   Hahella chejuens...
Feature 1                                                                                      
ABG51092   126 ---------vADIKIFNkrp-------------plRAGNLRARSAearyqls---------------------edengil 162  Trichodesmium er...
YP_526977   85 -------andDGIRILVddvg----------phvkQLGSRLDGYVngm------------------------------vl 117  Saccharophagus d...
CAE79162    91 i----vphkdGQNIIYLmdtwesnraseqgrtsvyWIGDLIKEADi---------------------------------r 133  Bdellovibrio bac...
YP_630894   91 evgyrrqgtnTNLVLFRtrdcnsv----vpatdacWADDTCANTHdcwddddntiaitlttydersgiiydsdisfnaar 166  Myxococcus xanth...
NP_633757   60 ----------CENKLYYts---------------lGSSGPLATTTetysgtsmtk----------------civrfnsdk 98   Methanosarcina m...
BAE55462   129 --------kdANFVLSHg----------------gNKGTVLASAYf---------------------------------- 150  Aspergillus oryzae
CAJ74546    88 kk--nhgepdGINIIDFgtike--------egvlgQNSFWFYTSGemfdsdi----------------------rfntkn 135  Candidatus Kuene...
XP_388268   96 --------neANFNLIFkk--------------ksHIEGLLAYAFfpg-----------------------------qkp 124  Gibberella zeae ...
YP_501914  377 -----ksgadGKNVLLFrd---------------lGSSGPIAQATywfssgi----------------------iseadv 414  Methanospirillum...
YP_436624   95 g---shndnnGRNEVYLdn---------------sLGGGVLAVTVtryhcyw---------------------lfgyqyg 135  Hahella chejuens...
Feature 1                                          ##  #     #                                 
ABG51092   163 SHNFVIWLSPMqv--------------gkYLPAAARHEFGHALGIWGHSPEk-------tDVMYYSQVAEPp-------- 213  Trichodesmium er...
YP_526977  118 NHTFQNWGTSCsyr------------rqyCAEVIAVHEFGHALGFAHEQNRdd------tDDMCAAEAQGTdg------- 172  Saccharophagus d...
CAE79162   134 LNAYDFNFYWNnqrlttavnparktsgevNIEALVLHEMGHVLGLKHKDGAg--------SVMATYLSSGDd-------- 197  Bdellovibrio bac...
YP_630894  167 FSFTTANGGTCfppvtt-------hcvatDVQNTATHEVGHLIGLDHTRATg--------STMNPSAPPGEvs------- 224  Myxococcus xanth...
NP_633757   99 SWSTTGASGYF------------------DVQSAATHEFGHWLSLGHSSNTe--------ATMYSTMSTGEtk------- 145  Methanosarcina m...
BAE55462   151 PNNKDLNFVYVysfafq-------pdwkpFLWRVFTHELGHVIGLRHEFAMnpgp--yfeGDAVQINERNPlsvmnyrre 221  Aspergillus oryzae
CAJ74546   136 TWSTDGSSDKF------------------DVQNIGTHELGHSLSLADLYSNs--------DSEKTMYGYGFagdt----s 185  Candidatus Kuene...
XP_388268  125 MNIVVMAFGMDlph-------------rlQLKNTFLHELGHVFGLRHEFAIekeq-kgaqLWSVPNEDSVMayk-----p 185  Gibberella zeae ...
YP_501914  415 EFNTYYSWTTDtasg-----------glkNIEAIAIHELGHWLNLKDLYGWvpgfpsdlsPIMKVMFGYNGdvign--tn 481  Methanospirillum...
YP_436624  136 IDETDIGFNNNiswnlgsln-ysnlgspySFESVALHELGHALGLLHENRWma-----tmNSYYPNSGPLGhyk------ 203  Hahella chejuens...
Feature 1                       
ABG51092   214 --PISSRDINTLKRIYL 228  Trichodesmium erythraeum IMS101
YP_526977  173 diYVGAWDLDSVLNYCN 189  Saccharophagus degradans 2-40
CAE79162   198 --RVNLAEVDSSALQCE 212  Bdellovibrio bacteriovorus HD100
YP_630894  225 krVVDSGSRGFVCDAYP 241  Myxococcus xanthus DK 1622
NP_633757  146 krSLHSDDIAGICYIYP 162  Methanosarcina mazei Go1
BAE55462   222 ppEIQQSDVEATKKFYS 238  Aspergillus oryzae
CAJ74546   186 qrTLHQDDMDGITYLYP 202  Candidatus Kuenenia stuttgartiensis
XP_388268  186 apQIQESDMTGIRTFYG 202  Gibberella zeae PH-1
YP_501914  482 lkTLSASEIAGIKWIYG 498  Methanospirillum hungatei JF-1
YP_436624  204 ewDPLADDRLGSRVIYP 220  Hahella chejuensis KCTC 2396

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap