1T9K,2YRF,6A34


Conserved Protein Domain Family
MtnA

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COG0182: MtnA 
5-methylthioribose/5-deoxyribulose 1-phosphate isomerase (methionine salvage pathway), a paralog of eIF-2B alpha subunit [Amino acid transport and metabolism]
Statistics
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PSSM-Id: 439952
Aligned: 462 rows
Threshold Bit Score: 378.229
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1T9K_A         5 LKTKTXEWS----G--NSLKLLDQRKLPFIEEYVECKTHEEVAHAIKEXIVRGAPAIGVAAAFGYVLGLRDYktgsl--t 76 
WP_011753897   1 -MVLALQWQ----EdaQTIRLLDQTLLPVEERYLDVDTVDALVAAIQSLAVRGAPALGAVGALGVVVAMRQAeregw-dd 74 
WP_015792152   1 --MRTLDWE----D--GALVTIDQCALPHREDILRLRTVDEVVEAIKRLAIRGAPALGVAGAFGVAIAARTHdadgrvde 72 
WP_012852322   2 tELQAVSWT----G--DALRLIDQTLLPHRLEHLEIREVDALVDAIVRLAVRGAPALGVAGAYGVALAMLQAeregw-dr 74 
NP_627236     15 TGIPALRWEeppeG--PVLVLLDQTRLPAEEVELVCTDPAALVEAIRSLAVRGAPLLGIAGGYGVALAAVRGfe------ 86 
WP_014985139   1 --MRTIDWV----D--GKVVILDQTLLPHREVVVTVTTAAQLAGEIARLAVRGAMALGVAGALGVALAALRAvergesle 72 
WP_014987742   1 MDDSSLIWD----D--GALVTIDQRGLPHEVRELRLRTVDEVIDAIRVLAIRGAPAIGIAGAFGVVLATAAHtvdgvvdt 74 
WP_095671559   3 SGFEAIVWK----E--NKIVLLDQTQIPISETYISYDELAPYIDAIQRLVVRGAPALGVAGAYGVVLVIDEAarkgh-sa 75 
WP_107257282   1 --MRTIDWV----D--GAVELIDQTALPARLTVLRLSTVEELVAAIQRLAVRGAPALGVAGALGVALAAHQPgd------ 66 
WP_114914309  19 PPLRPLRWDdspgG--PALLLLDQTRLPAEEREIVCTGVPTLIDAIQRLAVRGAPLLGLAGAYGVALAAARGcs------ 90 
1T9K_A        77 dwxKQVKETLARTRPTAVNLFWALNRXEKVFFenadre-----nlfeiLENEALKXAYEDIEVNKAIGKNGAQLIKD--- 148
WP_011753897  75 erlQVEVDRIRLARPTAVNLAWGVDQVRAAMPsgp-----------etVLKMAKAVVEEDEAANRTLSRLGADWILGrtg 143
WP_015792152  73 aavRAEAERLASARPTAVNLRWGVDQALAALSdgp-----------daVLAAALRVMDEDDRMNHQATVNAADVIVGlcp 141
WP_012852322  75 arlEAALERIRTARPTAVNLAGGVDRVRPLVDagl-----------aaVLEEAGRVLEEDVAANRAIGVHGAQWICArvp 143
NP_627236     87 --vEEAAAALAGARPTAVNLAVGVRRAQAAHRealagtgd-trqaaraALAAARALHREDTEASARMAAHGLALLDEllp 163
WP_014985139  73 ralDAAAVIMTEARPTAVNLAWGVEQVLAVRDggp-----------naILAAALAVRDADITANRTIGARGTDLLAG--- 138
WP_014987742  75 aavHADADRIAAARPTAVNLAWAVRRVRAEVErga-----------daVLAATLDLLAEDGRVNRAAATHAADLVQRlca 143
WP_095671559  76 qelEHNLDLLRDARPTAVNLAWAVEKIRKHLPegr-----------daVLAAAHQLASEDKQSSTDMGNIGADWLINklg 144
WP_107257282  67 --vASAVRRLETARPTAVNLARGVRRAAARLPega-----------daVLAEALAVRDEEIAASEAMARLGADLLAElc- 132
WP_114914309  91 --vGDAAEQLARARPTAVNLALGVRRAYDAHQahlaakpgdldgasaaTLAAARALHREDAAASAAMADHGLALLERlvp 168
1T9K_A       149 --GSTILTHCNAGALATVDY-GTALGVIRAAVESGKRIRVFADETRPYLQGARLTAWELXKDGIEVYVITDNXAGWLXKR 225
WP_011753897 144 reRVRVVTHCNTGALATSAW-GTAYGIIHELHDRGALEVVYVDETRPLLQGARLTSWELTRDEIPHLLEVDGAASSTIVR 222
WP_015792152 142 drPLRLLTHCNAGALATAGLrGTALGAVFELAERKLVEFVIVDETRPLLQGARLTSWELGKAGIPHRLCVDSAAASLMGR 221
WP_012852322 144 rrPLRILTHCNTGALATAGW-GTALGVVRELHARGLVEVVYADETRPLLQGSRLTAWELAHEGIPHYVLADGAAAGTILR 222
NP_627236    164 agGHRVLTHCNTGSLVSGGE-GTAFAVALAAHRSGRLRRLWVDETRPLLQGARLTAYEAARNDMAYTLLTDNAAGSLFAA 242
WP_014985139 139 --ARRILTHCNAGALAGVEC-GTALSVIGALDVANKLELVYACETRPLLQGSRLTAWELGRAGIAHTVIVDGAAAGMIVH 215
WP_014987742 144 drPLRLLTHCNTGRLATSAF-GTAIGALRVLAERGAVADVLVDETRPLLQGARLTAWELAEAGIPHRLTIDAAAAWAMAT 222
WP_095671559 145 skPMTLLTHCNTGSLATTGT-GTALGVIKEMHKRGFVKEVYADETRPLLQGSRLTAWELMKSDIPYHIEPDGAAAMAILS 223
WP_107257282 133 gaRPRLLTHCNTGALAAVVG-GTALGAILELHRRDALGAVLASETRPLLQGARLTAWELGRAGVPYRVAVDGAGPFLMAR 211
WP_114914309 169 ggGHRLLTHCNTGALVSGGE-GTALAVALAAHRAGRLRRLWVDETRPLLQGARLTAYEAARAGMPYSLLADNAAGSLLAA 247
1T9K_A       226 GLIDAVVVGADRIALNGDTANKIGTYSLAVLAKRNNIPFYVAAPVSTIDPTIRSGEEIPIEERRPEEVTHCG-------- 297
WP_011753897 223 GLVDVAIIGADRITANGDTANKVGSLALALACQRAGIPFVVAAPSSTVDLATAHGDDIAIEERDAAEVLSLG-------- 294
WP_015792152 222 GLVDCVVVGADRITANGDVANKIGTYGLAVSAAYHGIPIVVVAPESTVDESMGDGKLIEVEERDADEVRRVL-------- 293
WP_012852322 223 GLVDVAIIGADRIAANGDTANKIGSVGVALACADAGVPFVVAAPWSTVDLATATGADIPIESRAEEEVLCWQ-------- 294
NP_627236    243 GEVDAVLIGADRIAADGSVANKVGSYPLAVLARYHHVPFVVVAPVTTVDPDTPDGASIEVEQRPGYEVTEVTapqvpvag 322
WP_014985139 216 GRVDAVVVGADRIAANGDVVNKVGTLSHALAAARVGIPFVVAAPEATIDLTCPSGAEVPIEERAATEVLELG-------- 287
WP_014987742 223 GQVDCVLVGADRVTANGDVANKIGTYPLALAARHHGIPFIVVAPESTRDPNTVTGRDIVVEERAADEVTGFG-------- 294
WP_095671559 224 GRIDAALIGADRIAKNGDSANKIGSLSVALACHAAGIPFLVVAPESTVDRSIKTGSEIHIEIRGDEELTHFK-------- 295
WP_107257282 212 GEVDAVVLGADRICANGDVVNKIGTYAHALGARRAGIPFVVVAPESTVDLDTADGAQVEIEDRGAAEVLRYG-------- 283
WP_114914309 248 GQVDAVLVGADRIAADGSTANKVGSYPLAVLARHHGVPFVVVAPSTTVDPDTADGEAIVVEQRAAHEVAEFA-------- 319
1T9K_A       298 ---GNRIA---PEGVKVLNPAFDVTENTLITAIITEKGVIRPPFEE---NIK 340
WP_011753897 295 ---GHPTA---LPSTRVYNPAFDVTPHDLISAIVTDRGVVEPAARPapnLLA 340
WP_015792152 294 ---GMPVA---PEATEAFNPAFDVTPAELITAVVTEARVMRPQGAV----AG 335
WP_012852322 295 ---GVRVA---PEGSRGLNPAFDVTPARLIDALVTERGVLEPAHGR---TPA 337
NP_627236    323 aggGIPVA---PLGTQAYNPAFDVTPPELVTAIVTEEGVVSPVTTE---ALA 368
WP_014985139 288 ---GARIA---PAASTACNPAFDVTPADLVTAIVTEDRVITPSGq----SIG 329
WP_014987742 295 ---GVATA---PAGTAVFNPAFDVTPGDLVTAVVTELGVVHRGAGL---PPL 337
WP_095671559 296 ---GIQVA---PIGAKTFNPAFDVTPAKYISAVITEKHSYEIAEGQ---TL- 337
WP_107257282 284 ---GNPEAdpgPDTVDAVNPAFDVTPYELVTAIVTERRVIRLDRGE---RV- 328
WP_114914309 320 ---GVQVA---PPGATAYNPAFDVTPPGLISAIVTEKGVVSPVDVT---GMT 362
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