Conserved Protein Domain Family
SirB1

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COG2912: SirB1 
Regulator of sirC expression, contains transglutaminase-like and TPR domains [Signal transduction mechanisms]
Statistics
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PSSM-Id: 442156
Aligned: 170 rows
Threshold Bit Score: 168.85
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_007991606   1 MQsle---------------qaIQSNQLLCAGLLASRHs-VGVDTDISDCLQQLDRWARQAQIHAHISQPDHSAFLRLLT 64 
WP_011200364   1 MK--------------------YYQKALYDEMTSFYLItcDDEGDKLGRIRSLIGGLVRKARQVIGQEGDDKVRIHQLLQ 60 
WP_010944796   1 MDdiiqqlfkeverpqltvneqALQQYLYREIVRLTLLv--EPTISKPQIIGLLSALVKKARHYVNAD-NQAECIQQLLD 77 
WP_012340567   1 MK--------------------YYHKALYDEMTSFYLIthDNSSKEIRRIRGMIGGLVREARKKIDSNWETKRKIHHLLQ 60 
WP_041603131   1 MDniindifqeikkpksvvnkvQLQKFLYRELVRLTLMi--DDNLSEPQVLGLMSALVKRARYDVNGE-SDEERLHQLLR 77 
NP_439707      1 MK--------------------YYRRALYDKFVHFYLVi-SDDGSSEAQLRGKMGGLVRKARKKISPDWPKEEQIHQLLQ 59 
WP_013746989   1 MEknriidnde--alrialereKAGKYLLNQLISFNQIi--DADFKKSSIYSRLGHLIREFGKFIEGETDVKMRVHLLLQ 76 
WP_015433044   1 MEqinfqpp------fskkervALQQFLYRELIRISLLl--DNNLTAPQLYGKMAALVKKVRYAVNAD-TDLARIEQLLA 71 
WP_006249579   1 MDdiieellkeledpkvtisetELKKFLYREILRLTTLi--DKNVSEQQVFGQMSALVKKARYNVNGE-GDEERINQLLH 77 
WP_015674537   1 MDdiiqellkeledpkveisrsELQKYLYREMVRLTLLi--DNSLSEPQVLGLMSALVKKARYQVNAT-SDAERIQQLLD 77 
WP_007991606  65 FFYQELAFTGAHDSADTCQPNLLHEVFAYRNGTPVTLAVILSHVAQRLGFNARCVNFPGHFLVRCDivckedkalpdsfa 144
WP_011200364  61 LFYGDWGFHCDPEHYFEAENLYLAYVLETHSGMPVSLGALLLYLADSLKLPLYPVNFPTQLILRAEvd------------ 128
WP_010944796  78 LVYQEWRFHCDYQEYFYTDNLLLHRVIRSHRGMPLSIGAIVLYLAAKLQLPIYPVNFPTQLILRAEites---------- 147
WP_012340567  61 LMYGEWGFFCDPERYFALENLYLDQVLTQRRGMPVTLGAIVLYLAERLNLPIYPVNFPTQLILRADvd------------ 128
WP_041603131  78 LVYQEWGFHCHHAEYFYTDNLLINKVIRKFRGMPVSLGAVVLYLAASLNLPLYPVNFPTQLILRAElkne---------- 147
NP_439707     60 LFYGDWGFHCDPEDYFYARNLYLPYVFEHRQGMPVTLGAMVFYLAEALDLPIYPVNFPTQLILRAEvr------------ 127
WP_013746989  77 FFYGEKGFFCDRETYFHASNLMLPHVFATKEGTPAVLGSILLFIAANFHLPIRGVNFPTQFLLRVDvd------------ 144
WP_015433044  72 FFYQEQGFYCHHAEYYHSQNLMLNQVLDLKRGMPVSLGAVLLQLASVLDLPLYPVNFPTQLLLRAEmtle---------- 141
WP_006249579  78 LVYREWGFHCYYEDYFHTENLLLNQVIRKRRGMPVSLGAVALYLSAVLDLPLYPVNFPTQLVLRAEihqp---------- 147
WP_015674537  78 LVYQEWKFNCDYEGYFHTDNLLLNQVIRRHQGMPVSVGAIVLYLAAALDLPLYPVNFPTQLILRAEmkde---------- 147
WP_007991606 145 lstalnqahchktsdAehkqthSVMVDPINGHLLSVDVLKQKYFSVIEDIdnECMPKEALDPASNDEVVVHMLHQVKSSL 224
WP_011200364 129 --------------------neVAFIDPWNGHYLSQAHLQKLYEGAFGFG--AEISSEELERADVNTLLNRFRQLAKNAL 186
WP_010944796 148 ------------sgkKt-----VRFINPWDGQFLPLELLLKWLEGEVGYG--VELSPELLRRADPAELLERVETVFKMVL 208
WP_012340567 129 --------------------eeVAFIDPWNGQYMTYSQLKKLYEGAFGFG--TELSLEILEVADVQELTNRFCQLAKHAL 186
WP_041603131 148 ------------qgrTe-----VKFINPWDGSELSREKLEKWLEGEMGYG--VELNQEYLRIAEEDELLERLETVFKMAL 208
NP_439707    128 --------------------deVAFIDPWDGTYISQEKLQQLYEGAFGFG--AKIQPEELDRADLSLLYSRFEQLAKNAL 185
WP_013746989 145 --------------------deVAFIDPWNGKYVSQETIQTWLEGYLGFG--TPLSEEYVGVGDLIDLEDRMYQVLKSAL 202
WP_015433044 142 ------------ngrKe-----SRFIDLWNGTYLSFEQMEKLLEGEMGAS--TSLARQHLKIAEPSELLERLETVLKMAL 202
WP_006249579 148 ------------ngaTk-----VRFINPWNGEFLTIEMLNKWLEGEMGFG--VEVTPDLLRRAEPQELLERVETVFKMAL 208
WP_015674537 148 ------------kgkTt-----VRFINPWDGSFLPMELLIKWLEGEVGYG--VELSPDLLRKAQPNELLERVETVFKMAL 208
WP_007991606 225 INAKRYEHALRSIDLLIHLCPNNPYERRDRGVLLHELDCPQLAIVDYQYFIRQCPQDPAASLLAQQVKHMDITpp----v 300
WP_011200364 187 IRENRNDAAYRYIASLLRYHPEDPYEIRDRGLVLAQMGCYQAAAEDLQYFVDQCPQDPTSFLLTAQLAELKDHfs----e 262
WP_010944796 209 TREGKYEQTLRLIEYRLAENPDDPYEIRDRGMVLASMDCYQAAYDDLSYFIDQCPDDPSAAILKSEVKGLEQKskq--nq 286
WP_012340567 187 IREFRNNEAYQYIDMLLSRNPDDPYEIRDRGVVLTQMGCMQAALNDFEYFLEKCPEDPTALLLLPQLEYLQLEie----s 262
WP_041603131 209 TREGKYEEALRLIEYRLTISPEDPYEIRDRGMILASMDCYQAAFDDLSYFIDQCPDDPSAMMLKLEIAGLEKQska--sv 286
NP_439707    186 IREEHNDMAYHYIKNLMITDAENPYHIRDRGLVLAQMGAYPSALKDLEFFVEHCPKDPTAAFIRTQLLELKGEinkdtfp 265
WP_013746989 203 IREGRNEQALALIEHRLSETPDDPYEIRDRGVVYGNMECFHLAVPDLTYFVEQCPQDPVAPLIRLQLQDLKHip----ys 278
WP_015433044 203 TREKKFEETLRVIEYRLQEQPDDPYEIRDRGMILASMECYQAAIEDLNYFIDQCPDDPSAMMLKMEIPALEKQgka--fi 280
WP_006249579 209 TREGKYEETLRLIEYRLAFSPEDPYEIRDRGMVLASMDCYQAALEDINYFIDQCPEDPSAEILKMEVKGLQQKsqe--sv 286
WP_015674537 209 TREKKYEETLRVIEYRLAFSPEDPYEIRDRGMVLASMDCYQAAYEDLSYFIDQCPEDPSAVMLKLEMKGLEQKske--sr 286
WP_007991606 301 M 301
WP_011200364 263 L 263
WP_010944796 287 V 287
WP_012340567 263 I 263
WP_041603131 287 L 287
NP_439707    266 L 266
WP_013746989 279 F 279
WP_015433044 281 I 281
WP_006249579 287 V 287
WP_015674537 287 L 287
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